Martin Kristian Thomsen

  1. 2022
  2. Published

    Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic. / Duncan, Christopher J A; Skouboe, Morten K; Howarth, Sophie et al.

    In: The Journal of Experimental Medicine, Vol. 219, No. 6, e20212427, 06.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Accepted/In press

    A truncated reverse transcriptase enhances prime editing by split AAV vectors. / Gao, Zongliang; Ravendran, Sujan; Mikkelsen, Nanna S. et al.

    In: Molecular Therapy, 2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2021
  5. Published

    Three-dimensional culture models to study glioblastoma — current trends and future perspectives. / Vareecal Joseph, Justin; Blaavand, Mathilde S. ; Daubon, Thomas et al.

    In: Current Opinion in Pharmacology, Vol. 61, 12.2021, p. 91-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient. / Brinck Andersen, Nanna Sophie; Jørgensen, Sofie Eg; Skipper, Kristian Alsbjerg et al.

    In: Autophagy, Vol. 17, No. 9, 09.2021, p. 2449-2464.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Targeting AP-1 transcription factors by CRISPR in the prostate. / Thomsen, Martin Kristian; Cai, Huiqiang; Stoltze, Iben C. et al.

    In: OncoTarget, Vol. 12, No. 19, 09.2021, p. 1956-1961.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    The CRISPR/Cas9 Minipig—A Transgenic Minipig to Produce Specific Mutations in Designated Tissues. / Berthelsen, Martin Fogtmann; Riedel, Maria; Cai, Huiqiang et al.

    In: Cancers, Vol. 13, No. 12, 3024, 06.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun. / Riedel, Maria; Berthelsen, Martin F.; Cai, Huiqiang et al.

    In: Oncogene, Vol. 40, No. 13, 04.2021, p. 2437–2447.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Comparative analysis of Stk11/Lkb1 versus Pten deficiency in lung adenocarcinoma induced by CRISPR/Cas9. / Berthelsen, Martin F.; Leknes, Siv L.; Riedel, Maria et al.

    In: Cancers, Vol. 13, No. 5, 974, 02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production. / Reinert, Line S; Rashidi, Ahmad S; Tran, Diana N et al.

    In: Journal of Clinical Investigation, Vol. 131, No. 1, e136824, 01.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    FRMD6 has tumor suppressor functions in prostate cancer. / Haldrup, Jakob; Strand, Siri H; Cieza-Borrella, Clara et al.

    In: Oncogene, Vol. 40, No. 4, 01.2021, p. 763–776.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. 2020
  14. Published

    Author Correction : STEEP mediates STING ER exit and activation of signaling (Nature Immunology, (2020), 21, 8, (868-879), 10.1038/s41590-020-0730-5). / Zhang, Bao-cun; Nandakumar, Ramya; Reinert, Line S. et al.

    In: Nature Immunology, Vol. 21, No. 11, 11.2020, p. 1468-1469.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  15. Published

    The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma. / Thomsen, Martin K.; Skouboe, Morten K.; Boularan, Cedric et al.

    In: Oncogene, Vol. 39, No. 8, 02.2020, p. 1652-1664.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    STEEP mediates STING ER exit and activation of signaling. / Zhang, Bao cun; Nandakumar, Ramya; Reinert, Line S. et al.

    In: Nature Immunology, Vol. 21, No. 8, 2020, p. 868-879.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. 2019
  18. Published

    Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling. / Nandakumar, Ramya; Tschismarov, Roland; Meissner, Felix et al.

    In: Nature Microbiology, Vol. 4, 04.2019, p. 701-713.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Dominant negative SERPING1 variants cause intracellular retention of C1-inhibitor in hereditary angioedema. / Haslund, Didde; Ryø, Laura Barrett; Majidi, Sara Seidelin et al.

    In: Journal of Clinical Investigation, Vol. 129, No. 1, CI98869, 2019, p. 388-405.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    cAIMP administration in humanized mice induces a chimerization-level-dependent STING response. / Andersen, Anna H.F.; Olesen, Rikke; Jønsson, Kasper L. et al.

    In: Immunology, Vol. 157, No. 2, 2019, p. 163-172.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. 2018
  22. Published

    Virus delivery of CRISPR guides to the murine prostate for gene alteration. / Riedel, Maria; Berthelsen, Martin F.; Bakiri, Latifa et al.

    In: Journal of Visualized Experiments, Vol. 134, e57525, 27.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice. / Skouboe, Morten K; Knudsen, Alice; Reinert, Line S et al.

    In: P L o S Pathogens, Vol. 14, No. 4, e1006976, 02.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2017
  25. Published

    A genetically inducible porcine model of intestinal cancer. / Callesen, Morten Møbjerg; Árnadóttir, Sigrid Salling; Lyskjær, Iben et al.

    In: Molecular Oncology, Vol. 11, No. 11, 11.2017, p. 1616-1629.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation. / Bakiri, Latifa; Hamacher, Rainer; Graña, Osvaldo et al.

    In: Journal of Experimental Medicine, Vol. 214, No. 5, 05.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Pancreas specific expression of oncogenes in a porcine model. / Berthelsen, Martin Fogtmann; Callesen, Morten Møbjerg; Østergaard, Tanja Stenshøj et al.

    In: Transgenic Research, Vol. 26, No. 5, 2017, p. 603-612.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2016
  29. Published

    Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. / Reinert, Line S; Lopušná, Katarína; Winther, Henriette et al.

    In: Nature Communications, Vol. 7, 13348, 10.11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    The CRISPR-Cas9 Minipig. / Berthelsen, Martin Fogtmann; Møller, Simone; Callesen, Henrik et al.

    2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  31. Published

    Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection. / Thomsen, Martin K; Nandakumar, Ramya; Stadler, Daniela et al.

    In: Hepatology, Vol. 64, No. 3, 16.06.2016, p. 746-759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses. / Holm, Christian K; Rahbek, Stine H; Gad, Hans Henrik et al.

    In: Nature Communications, Vol. 7, 10680, 19.02.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. 2015
  34. Published

    An innate antiviral pathway acting before interferons at epithelial surfaces. / Iversen, Marie B; Reinert, Line S; Thomsen, Martin K et al.

    In: Nature Immunology, 30.11.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Loss of JUNB/AP-1 promotes invasive prostate cancer. / Thomsen, M K; Bakiri, L; Hasenfuss, Sebastian C et al.

    In: Cell Death and Differentiation, Vol. 22, No. 4, 04.2015, p. 574-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. 2014
  37. Published

    Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers. / Hasenfuss, Sebastian C; Bakiri, Latifa; Thomsen, Martin K et al.

    In: Cell Metabolism, Vol. 19, No. 1, 07.01.2014, p. 84-95.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism. / Hasenfuss, Sebastian C; Bakiri, Latifa; Thomsen, Martin K et al.

    In: Hepatology, Vol. 59, No. 1, 01.2014, p. 261-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. 2013
  40. Published

    JUNB/AP-1 controls IFN-γ during inflammatory liver disease. / Thomsen, Martin K; Bakiri, Latifa; Hasenfuss, Sebastian C et al.

    In: Journal of Clinical Investigation, Vol. 123, No. 12, 12.2013, p. 5258-68.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma. / Francis, Jeffrey C; Thomsen, Martin K; Taketo, Makoto M et al.

    In: P L o S Genetics, Vol. 9, No. 1, 2013, p. e1003180.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 2010
  43. Published

    Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis. / Francis, Jeffrey C; McCarthy, Afshan; Thomsen, Martin K et al.

    In: P L o S Genetics, Vol. 6, No. 6, 24.06.2010, p. e1000995.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. / Thomsen, Martin K; Ambroisine, Laurence; Wynn, Sarah et al.

    In: Cancer Research, Vol. 70, No. 3, 01.02.2010, p. 979-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. 2008
  46. Published

    The role of Sox9 in prostate development. / Thomsen, Martin K; Francis, Jeffrey C; Swain, Amanda.

    In: Differentiation, Vol. 76, No. 6, 07.2008, p. 728-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Sox9 is required for prostate development. / Thomsen, Martin K; Butler, Christopher M; Shen, Michael M et al.

    In: Developmental Biology, Vol. 316, No. 2, 15.04.2008, p. 302-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review