Marianne Gerberg Skals

  1. 2020
  2. Published

    Prevention of P2 Receptor-Dependent Thrombocyte Activation by Pore-Forming Bacterial Toxins Improves Outcome in A Murine Model of Urosepsis. / Christensen, Mette G.; Johnsen, Nanna; Skals, Marianne; Hamilton, Aimi D.M.; Rubak, Peter; Hvas, Anne Mette; Praetorius, Helle.

    In: International Journal of Molecular Sciences, Vol. 21, No. 16, 5652, 08.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium. / Christensen, Inga Baasch; Wu, Qi; Bohlbro, Anders Solitander; Skals, Marianne Gerberg; Damkier, Helle Hasager; Hübner, Christian Andreas; Fenton, Robert Andrew; Praetorius, Jeppe.

    In: Fluids and Barriers of the CNS, Vol. 17, No. 1, 2, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2019
  5. Published

    P2X1 receptor blockers reduce the number of circulating thrombocytes and the overall survival of urosepsis with haemolysin-producing Escherichia coli. / Skals, Marianne; Greve, Anne Sofie; Fagerberg, Steen K.; Johnsen, Nanna; Christensen, Mette G.; Praetorius, Helle A.

    In: Purinergic Signalling, Vol. 15, No. 2, 06.2019, p. 265-276.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    α-Haemolysin production, as a single factor, causes fulminant sepsis in a model of Escherichia coli-induced bacteraemia. / Johnsen, Nanna; Hamilton, Aimi D.M.; Greve, Anne Sofie; Christensen, Mette G.; Therkildsen, Jacob R.; Wehmöller, Julia; Skals, Marianne; Praetorius, Helle A.

    In: Cellular Microbiology, Vol. 21, No. 6, e13017, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. 2017
  8. Published

    Loop Diuretics Diminish Hemolysis Induced by α-Hemolysin from Escherichia coli. / Söderström, Carl Martin; Fagerberg, Steen K; Brogaard, Mette B; Leipziger, Jens; Skals, Marianne; Praetorius, Helle A.

    In: Journal of Membrane Biology, Vol. 250, No. 3, 06.2017, p. 301-313.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    P2X1, P2X4, and P2X7 Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli. / Greve, Anne-Sofie; Skals, Marianne; Fagerberg, Steen K; Tonnus, Wulf; Ellermann-Eriksen, Svend; Evans, Richard J; Linkermann, Andreas; Praetorius, Helle A.

    In: Frontiers in cellular and infection microbiology, Vol. 7, 113, 2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2016
  11. Published

    Inhibition of P2X receptors protects human monocytes against damage by leukotoxin from Aggregatibacter actinomycetemcomitans and α-hemolysin from Escherichia coli. / Fagerberg, Steen K; Jakobsen, Martin R; Skals, Marianne; Praetorius, Helle A.

    In: Infection and Immunity, Vol. 84, No. 11, 15.11.2016, p. 3114-3130 .

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. 2015
  13. Published

    [Ca2+]i oscillations and IL-6 release induced by alpha-hemolysin from Escherichia coli require P2 receptor activation in renal epithelia. / Christensen, Mette; Fagerberg, Steen Kåre; de Bruijn, Pauline I.A.; Bjælde, Randi Groslier; Jakobsen, Helle; Leipziger, Jens Georg; Skals, Marianne Gerberg; Prætorius, Helle.

    In: Journal of Biological Chemistry, Vol. 290, No. 23, 2015, p. 14776-84.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2014
  15. Published

    Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore. / Skals, Marianne; Bjaelde, Randi G; Reinholdt, Jesper; Poulsen, Knud; Vad, Brian S; Otzen, Daniel; Leipziger, Jens; Praetorius, Helle A.

    In: Journal of Biological Chemistry, Vol. 289, 04.07.2014, p. 19098-19109.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans. / Munksgaard, Peter Svenssen; Skals, Marianne Gerberg; Reinholdt, Jesper; Poulsen, Knud; Jensen, Maria Risager; Yang, Chuanxu; Leipziger, Jens; Vorup-Jensen, Thomas; Praetorius, Helle A.

    In: Infection and Immunity, Vol. 82, No. 6, 06.2014, p. 2219-28.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. 2013
  18. Published

    Mechanisms of cytolysin-induced cell damage -- a role for auto- and paracrine signalling. / Skals, Marianne Gerberg; Prætorius, Helle.

    In: Acta Physiologica (Print), Vol. 209, No. 2, 2013, p. 95.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    P2X receptor stimulation amplifies complement-induced haemolysis. / Hjel, Julie L; Skals, Marianne Gerberg; Leipziger, Jens Georg; Prætorius, Helle.

    In: Pflügers Archiv - European Journal of Physiology, Vol. 465, 2013, p. 529-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    P2X receptor-dependent erythrocyte damage by α-hemolysin from Escherichia coli triggers phagocytosis by THP-1 cells. / Fagerberg, Steen Kåre; Skals, Marianne Gerberg; Leipziger, Jens Georg; Prætorius, Helle.

    In: Toxins, Vol. 5, 2013, p. 472.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. 2012
  22. Published

    Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes. / Munksgaard, Peter Svenssen; Vorup-Jensen, Thomas; Reinholdt, Jesper; Söderström, Carl Martin; Poulsen, Knud; Leipziger, Jens; Praetorius, Helle A; Skals, Marianne.

    In: Cellular Microbiology, Vol. 14, No. 12, 2012, p. 1904-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Purinergic signalling and volume regulation in erythrocytes induced by bacterial toxins. / Skals, Marianne Gerberg.

    Aarhus Universitet, 2012.

    Research output: Book/anthology/dissertation/reportPh.D. thesis

  24. 2011
  25. Published

    Python Erythrocytes Are Resistant to α-Hemolysin from Escherichia coli. / Larsen, Casper Kornbech; Skals, Marianne Gerberg; Nielsen, Tobias Wang; Cheema, Muhammad Umar; Leipziger, Jens Georg; Prætorius, Helle.

    In: Journal of Membrane Biology, Vol. 244, No. 3, 08.11.2011, p. 131-140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Combretastatin-induced hypertension and the consequences for its combination with other therapies. / Busk, Morten; Bohn, Anja Bille; Skals, Marianne; Wang, Tobias; Horsman, Michael R.

    In: Vascular Pharmacology, Vol. 54, No. 1-2, 2011, p. 13-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Haemolysis induced by α-toxin from Staphylococcus aureus requires P2X receptor activation. / Skals, Marianne Gerberg; Leipziger, Jens Georg; Prætorius, Helle.

    In: Pflügers Archiv - European Journal of Physiology, Vol. 462, 2011, p. 669-679.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2010
  29. Published

    Escherichia coli α-hemolysin triggers shrinkage of erythrocytes via KCa3.1 and TMEM16A channels with subsequent phosphatidylserine exposure. / Skals, Marianne; Jensen, Uffe B.; Ousingsawat, Jiraporn; Kunzelmann, Karl; Leipziger, Jens; Praetorius, Helle A.

    In: Journal of Biological Chemistry, Vol. 285, No. 20, 14.05.2010, p. 15557-15565.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET. / Busk, Morten; Munk, Ole Lajord; Jakobsen, Steen; Wang, Tobias; Skals, Marianne; Steiniche, Torben; Horsman, Michael Robert; Overgaard, Jens.

    In: Acta Oncologica, Vol. 49, No. 7, 2010, p. 922-33.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Escherichia coli α-hemolysin triggers shrinkage of erythrocytes via K(Ca)3.1 and TMEM16A channels with subsequent phosphatidylserine exposure. / Skals, Marianne Gerberg; Jensen, Uffe Birk; Ousingsawat, Jiraporn; Kunzelmann, Karl; Leipziger, Jens Georg; Prætorius, Helle.

    In: Journal of Biological Chemistry, Vol. 285, 2010, p. 15557-15565.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. 2009
  33. Published

    α-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis. / Skals, Marianne Gerberg; Jørgensen, Niklas R; Leipziger, Jens Georg; Prætorius, Helle.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, 2009, p. 4030-4035.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. 2006
  35. Published

    Evidence for a respiratory component, similar to mammalian respiratory sinus arrhythmia, in the heart rate variability signal from the rattlesnake, Crotalus durissus terrificus. / Campbell, Hamish A; Leite, Cleo A C; Wang, Tobias; Skals, Marianne Gerberg; Abe, Augusto S; Egginton, Stuart; Rantin, F Tadeu; Bishop, Charles M; Taylor, Edwin W.

    In: Journal of Experimental Biology, Vol. 209, No. Pt 14, 07.2006, p. 2628-36.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Cardiovascular changes under normoxic and hypoxic conditions in the air-breathing teleost Synbranchus marmoratus : importance of the venous system. / Skals, Marianne Gerberg; Skovgaard, Nini; Taylor, Edwin W; Leite, Cleo A C; Abe, Augusto S; Wang, Tobias.

    In: Journal of Experimental Biology, Vol. 209, No. Pt 20, 2006, p. 4167-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. 2005
  38. Published

    Venous tone and cardiac function in the South American rattlesnake Crotalus durissus : mean circulatory filling pressure during adrenergic stimulation in anaesthetised and fully recovered animals. / Skals, Marianne Gerberg; Skovgaard, Nini; Abe, Augusto S; Wang, Tobias.

    In: Journal of Experimental Biology, Vol. 208, No. Pt 19, 2005, p. 3747-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. 2004
  40. Published

    Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia. / Nakayama, Koh; Frew, Ian J; Hagensen, Mette; Skals, Marianne Gerberg; Habelhah, Hasem; Bhoumik, Anindita; Kadoya, Takayuki; Erdjument-Bromage, Hediye; Tempst, Paul; Frappell, Peter B; Bowtell, David D; Ronai, Ze'ev.

    In: Cell, Vol. 117, No. 7, 25.06.2004, p. 941-52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review