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Maria Speed
Investigating the causal relationship between neuroticism and depression via Mendelian Randomization
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Letter › peer-review
Links
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426667/pdf/nihms-1008461.pdf
Accepted manuscript
DOI
- https://doi.org/10.1111/acps.13009
Final published version
- Doug Speed
- Gibran Hemani, University of Bristol ,
- Maria S Speed
- Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium ,
- Anders D Børglum
- Aarhus Institute of Advanced Studies
- Department of Molecular Biology and Genetics - Bioinformatics Research Centre (BiRC)
- Department of Clinical Medicine - Department of Affective Disorders
- Department of Biomedicine - Forskning og uddannelse, Øst
- DANDRITE
- Department of Clinical Medicine - NIDO | Center for Forskning og Uddannelse
- Department of Clinical Medicine - Translational Neuropsychiatry Unit
- Department of Economics and Business Economics
- National Centre for Register-based Research - CIRRAU - Centre for Integrated Register-based Research
- National Centre for Register-based Research
Neuroticism is a heritable personality trait, characterized by negative emotions such as worrying, feelings of guilt, loneliness and being easily hurt. Increased levels of neuroticism are associated with poor mental health - development of depression in particular - but it remains uncertain whether this association represents a causal effect [1]. Here, we use Mendelian randomization (MR) to investigate whether neuroticism is a causal risk factor for development of depression. This article is protected by copyright. All rights reserved.
| Original language | English |
|---|---|
| Journal | Acta Psychiatrica Scandinavica |
| Volume | 139 |
| Issue | 4 |
| Pages (from-to) | 395-397 |
| Number of pages | 3 |
| ISSN | 0001-690X |
| DOIs | |
| Publication status | Published - 2019 |
Bibliographical note
This article is protected by copyright. All rights reserved.
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