Department of Biomedicine

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Maria Andreasen

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  1. 2021
  2. Published

    Modulating kinetics of the amyloid-like aggregation of s. Aureus phenol-soluble modulins by changes in ph. / Zaman, Masihuz; Andreasen, Maria.

    In: Microorganisms, Vol. 9, No. 1, 117, 01.2021, p. 1-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. 2020
  4. Published

    Cross-talk between individual phenol- soluble modulins in staphylococcus aureus biofilm enables rapid and efficient amyloid formation. / Zaman, Masihuz; Andreasen, Maria.

    In: eLife, Vol. 9, e59776, 12.2020, p. 1-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  5. 2019
  6. Published

    Hyperosmotic stress induces cell-dependent aggregation of α-synuclein. / Fragniere, Alexandra M.C.; Stott, Simon R.W.; Fazal, Shaline V.; Andreasen, Maria; Scott, Kirsten; Barker, Roger A.

    In: Scientific Reports, Vol. 9, 2288, 12.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  7. Published

    Fabrication and Characterization of Reconstituted Silk Microgels for the Storage and Release of Small Molecules. / Liu, Xizhou; Toprakcioglu, Zenon; Dear, Alexander J.; Levin, Aviad; Ruggeri, Francesco Simone; Taylor, Christopher G.; Hu, Mengsha; Kumita, Janet R.; Andreasen, Maria; Dobson, Christopher M.; Shimanovich, Ulyana; Knowles, Tuomas P.J.

    In: Macromolecular Rapid Communications, Vol. 40, No. 8, 1800898, 04.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  8. Published

    Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation. / Rasmussen, Casper B.; Christiansen, Gunna; Vad, Brian S.; Lynggaard, Carina; Enghild, Jan J.; Andreasen, Maria; Otzen, Daniel.

    In: Protein Science, Vol. 28, No. 3, 01.03.2019, p. 633-642.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  9. Published

    Physical Determinants of Amyloid Assembly in Biofilm Formation. / Andreasen, Maria; Meisl, Georg; Taylor, Jonathan D; Michaels, Thomas C T; Levin, Aviad; Otzen, Daniel E; Chapman, Matthew R; Dobson, Christopher M; Matthews, Steve J; Knowles, Tuomas P J.

    In: mBio, Vol. 10, No. 1, e02279-18, 08.01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. 2018
  11. Published

    Corneal dystrophy mutations drive pathogenesis by targeting TGFBIp stability and solubility in a latent amyloid-forming domain. / Stenvang, Marcel; Schafer, Nicholas P; Malmos, Kirsten Gade; Pérez, Adriana-Michelle Wolf; Niembro, Olatz; Sormanni, Pietro; Basaiawmoit, Rajiv Vaid; Christiansen, Gunna; Andreasen, Maria; Otzen, Daniel E.

    In: Journal of Molecular Biology, Vol. 430, No. 8, 13.04.2018, p. 1116-1140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  12. 2017
  13. Published

    Absolute Quantification of Amyloid Propagons by Digital Microfluidics. / Pfammatter, Manuela; Andreasen, Maria; Meisl, Georg; Taylor, Christopher G.; Adamcik, Jozef; Bolisetty, Sreenath; Sánchez-Ferrer, Antoni; Klenerman, David ; Dobson, Christopher M; Mezzenga, Raffaele; Knowles, Tuomas P J; Aguzzi, Adriano ; Hornemann, Simone.

    In: Analytical Chemistry, Vol. 89, No. 22, 2017, p. 12306.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  14. 2016
  15. Published

    Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones. / Taylor, Jonathan D.; Hawthorne, William J. ; Lo, Joanne; Dear, Alexander ; Jain, Neha; Meisl, Georg; Andreasen, Maria; Fletcher, Catherine ; Koch, Marion ; Darvill, Nicholas ; Scull, Nicola ; Escalera-Maurer, Andrés ; Sefer, Lea; Wenman, Rosemary ; Lambert, Sebastian ; Jean, Jisoo; Xu, Yingqi ; Turner, Benjamin ; Kazarian, Sergei G.; Chapman, Matthew R. ; Bubeck, Doryen ; de Simone, Alfonso ; Knowles, Tuomas P J; Matthews, Steve J.

    In: Scientific Reports, Vol. 6, 24656 , 21.04.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  16. Published

    Near-complete 1H, 13C, 15N resonance assignments of dimethylsulfoxide-denatured TGFBIp FAS1-4 A546T. / Kulminskaya, Natalia V; Yoshimura, Yuichi; Runager, Kasper; Sørensen, Charlotte S; Bjerring, Morten; Andreasen, Maria; Otzen, Daniel E; Enghild, Jan J; Nielsen, Niels Christian; Mulder, Frans A A.

    In: Biomolecular N M R Assignments, Vol. 10, No. 1, 2016, p. 25-29.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  17. 2015
  18. Published

    Scaffolded multimers of hIAPP20-29 peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP20-29 peptide fragment. / Christoffersen, Heidi F; Andreasen, Maria; Zhang, Shuai; Nielsen, Erik Holm; Christiansen, Gunna; Dong, Mingdong; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 12, 12.2015, p. 1890-1897.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. Published

    Interactions between misfolded protein oligomers and membranes : A central topic in neurodegenerative diseases? / Andreasen, Maria; Lorenzen, Nikolai; Otzen, Daniel.

    In: B B A - Molecular and Cell Biology of Lipids, Vol. 1848, No. 9, 09.2015, p. 1897-1907.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20. Published

    Preventing peptide and protein misbehavior. / Arosio, Paolo; Meisl, Georg; Andreasen, Maria; Knowles, Tuomas P J.

    In: Proc. Nat. Acad. Sci, USA (PNAS), Vol. 112, No. 17, 2015, p. 5267–5268.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. 2014
  22. Published

    The Importance of Being Capped : Terminal Capping of an Amyloidogenic Peptide Affects Fibrillation Propensity and Fibril Morphology. / Andreasen, Maria; Skeby, Katrine Kirkeby; Zhang, Shuai; Nielsen, Erik Holm; Klausen, Lasse Hyldgaard; Frahm, Heidi; Christiansen, Gunna; Skrydstrup, Troels; Dong, Mingdong; Schiøtt, Birgit; Otzen, Daniel.

    In: Biochemistry, Vol. 53, No. 44, 21.10.2014, p. 6968-6980.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  23. Published

    High stability and cooperative unfolding of cytotoxic α-synuclein oligomers. / Paslawski, Wojciech; Andreasen, Maria; Nielsen, Søren Bang; Lorenzen, Nikolai; Thomsen, Karen; Kaspersen, Jørn Døvling; Pedersen, Jan Skov; Otzen, Daniel.

    In: Biochemistry, Vol. 53, No. 39, 12.09.2014, p. 6252-6263.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  24. Published

    The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. / Lorenzen, Nikolai; Nielsen, Søren Bang; Buell, Alexander K. ; Kaspersen, Jørn Døvling; Arosio, Paolo; Vad, Brian Stougaard; Paslawski, Wojciech; Christiansen, Gunna; Valnickova Hansen, Zuzana; Andreasen, Maria; Enghild, Jan Johannes; Pedersen, Jan Skov; Dobson, Christopher M; Knowles, Tuomas P J; Otzen, Daniel.

    In: Journal of the American Chemical Society, Vol. 136, No. 10, 16.02.2014, p. 3859-3868.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  25. Published

    The Molecular Basis for TGFBIp-Related Corneal Dystrophies. / Stenvang, Marcel Renè; Andreasen, Maria; Otzen, Daniel.

    Bio-nanoimaging : Protein Misfolding and Aggregation. Elsevier, 2014. p. 179-188.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research

  26. 2013
  27. Published

    Coexistence of ribbon and helical fibrils originating from hIAPP20-29 revealed by quantitative nanomechanical atomic force microscopy. / Zhang, Shuai; Andreasen, Maria; Nielsen, Jakob T; Liu, Lei; Nielsen, Erik H; Song, Jie; Ji, Gang; Sun, Fei; Skrydstrup, Troels; Besenbacher, Flemming; Nielsen, Niels C; Otzen, Daniel E; Dong, Mingdong.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 8, 2013, p. 2798-2803.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  28. 2012
  29. Published

    Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways with Different Oligomeric Intermediates. / Andreasen, Maria; Nielsen, Søren Bang; Runager, Kasper; Christiansen, Gunna; Nielsen, Niels Christian; Enghild, Jan J; Otzen, Daniel.

    In: Journal of Biological Chemistry, Vol. 287, No. 41, 05.10.2012, p. 34730-34742.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  30. Published

    Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone. / Andreasen, Maria; Nielsen, Søren Bang; Mittag, Tina; Bjerring, Morten; Nielsen, Jakob T; Zhang, Shuai; Nielsen, Erik H; Jeppesen, Martin; Christiansen, Gunna; Besenbacher, Flemming; Dong, Mingdong; Nielsen, Niels Christian; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1824, No. 2, 2012, p. 274-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  31. 2011
  32. Published

    Aβ1-16 Can Aggregate and induce the Production of Reactive Oxygen Species, Nitric Oxide, and Inflammatory Cytokines. / Du, Xue-ting; Wang, Li; Wang, Yu-jiong; Andreasen, Maria; Zhan, Da-wei; Feng, Ying; Li, Min; Zhao, Min; Otzen, Daniel; Xue, Di; Yang, Yang; Liu, Rui-tian.

    In: Journal of Alzheimer's Disease, Vol. 27, No. 2, 11.2011, p. 401-413.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  33. Published

    Human Phenotypically Distinct TGFBI Corneal Dystrophies Are Linked to the Stability of the Fourth FAS1 Domain of TGFBIp. / Runager, Kasper; Basaiawmoit, Rajiv V; Deva, Taru; Andreasen, Maria; Valnickova, Zuzana; Sørensen, Charlotte S; Karring, Henrik; Thøgersen, Ida B; Christiansen, Gunna; Underhaug, Jarl; Kristensen, Torsten; Nielsen, Niels Chr; Klintworth, Gordon K; Otzen, Daniel E; Enghild, Jan J.

    In: Journal of Biological Chemistry, Vol. 286, No. 7, 18.02.2011, p. 4951-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  34. Published

    Modulation of Protein aggregation : Biophysical investigation of fibrillation of Fas1-4 and hIAPP20-29. / Andreasen, Maria.

    2011.

    Research output: Book/anthology/dissertation/report › Ph.D. thesis