Manuel Mattheisen

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Michael H Cho, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: remhc@channing.harvard.edu.
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  • Merry-Lynn N McDonald, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Xiaobo Zhou, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Manuel Mattheisen
  • Peter J Castaldi, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Craig P Hersh, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Dawn L Demeo, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Jody S Sylvia, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • John Ziniti, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Nan M Laird, Harvard School of Public Health, Boston, MA, USA.
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  • Christoph Lange, Harvard School of Public Health, Boston, MA, USA.
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  • Augusto A Litonjua, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • David Sparrow, School of Public Health and School of Medicine, Boston University, Boston, MA, USA; Veterans Administration Boston Healthcare System, Boston, MA, USA.
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  • Richard Casaburi, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA, USA.
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  • R Graham Barr, Department of Medicine, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, NY, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
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  • Elizabeth A Regan, National Jewish Health, Denver, CO, USA; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
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  • Barry J Make, National Jewish Health, Denver, CO, USA.
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  • John E Hokanson, Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
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  • Sharon Lutz, Department of Bioinformatics and Statistics, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
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  • Tanda Murray Dudenkov, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
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  • Homayoon Farzadegan, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
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  • Jacqueline B Hetmanski, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
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  • Ruth Tal-Singer, GlaxoSmithKline Research and Development, King Of Prussia, PA, USA.
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  • David A Lomas, University College London, London, UK
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  • Per Bakke, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
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  • Amund Gulsvik, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
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  • James D Crapo, National Jewish Health, Denver, CO, USA.
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  • Edwin K Silverman, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
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  • Terri H Beaty, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
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  • NETT Genetics, ICGN, ECLIPSE and COPDGene Investigators
The genetic risk factors for susceptibility to chronic obstructive pulmonary disease (COPD) are still largely unknown. Additional genetic variants are likely to be identified by genome-wide association studies in larger cohorts or specific subgroups. We sought to identify risk loci for moderate to severe and severe COPD with data from several cohort studies.
Original languageEnglish
JournalThe Lancet Respiratory Medicine
Volume2
Issue3
Pages (from-to)214-25
Number of pages12
ISSN2213-2600
DOIs
Publication statusPublished - Mar 2014

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