Manuel Mattheisen

Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia

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Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia. / Mattheisen, Manuel; Mühleisen, Thomas W; Strohmaier, Jana; Treutlein, Jens; Nenadic, Igor; Alblas, Margrieta; Meier, Sandra; Degenhardt, Franziska; Herms, Stefan; Hoffmann, Per; Witt, Stephanie H; Giegling, Ina; Sauer, Heinrich; Schulze, Thomas G; Rujescu, Dan; Nöthen, Markus M; Rietschel, Marcella; Cichon, Sven.

In: Schizophrenia research, Vol. 141, No. 2-3, 11.2012, p. 262-5.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Mattheisen, M, Mühleisen, TW, Strohmaier, J, Treutlein, J, Nenadic, I, Alblas, M, Meier, S, Degenhardt, F, Herms, S, Hoffmann, P, Witt, SH, Giegling, I, Sauer, H, Schulze, TG, Rujescu, D, Nöthen, MM, Rietschel, M & Cichon, S 2012, 'Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia', Schizophrenia research, vol. 141, no. 2-3, pp. 262-5. https://doi.org/10.1016/j.schres.2012.08.027

APA

Mattheisen, M., Mühleisen, T. W., Strohmaier, J., Treutlein, J., Nenadic, I., Alblas, M., Meier, S., Degenhardt, F., Herms, S., Hoffmann, P., Witt, S. H., Giegling, I., Sauer, H., Schulze, T. G., Rujescu, D., Nöthen, M. M., Rietschel, M., & Cichon, S. (2012). Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia. Schizophrenia research, 141(2-3), 262-5. https://doi.org/10.1016/j.schres.2012.08.027

CBE

Mattheisen M, Mühleisen TW, Strohmaier J, Treutlein J, Nenadic I, Alblas M, Meier S, Degenhardt F, Herms S, Hoffmann P, Witt SH, Giegling I, Sauer H, Schulze TG, Rujescu D, Nöthen MM, Rietschel M, Cichon S. 2012. Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia. Schizophrenia research. 141(2-3):262-5. https://doi.org/10.1016/j.schres.2012.08.027

MLA

Vancouver

Mattheisen M, Mühleisen TW, Strohmaier J, Treutlein J, Nenadic I, Alblas M et al. Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia. Schizophrenia research. 2012 Nov;141(2-3):262-5. https://doi.org/10.1016/j.schres.2012.08.027

Author

Mattheisen, Manuel ; Mühleisen, Thomas W ; Strohmaier, Jana ; Treutlein, Jens ; Nenadic, Igor ; Alblas, Margrieta ; Meier, Sandra ; Degenhardt, Franziska ; Herms, Stefan ; Hoffmann, Per ; Witt, Stephanie H ; Giegling, Ina ; Sauer, Heinrich ; Schulze, Thomas G ; Rujescu, Dan ; Nöthen, Markus M ; Rietschel, Marcella ; Cichon, Sven. / Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia. In: Schizophrenia research. 2012 ; Vol. 141, No. 2-3. pp. 262-5.

Bibtex

@article{6924590f0f064081b24c2caebba6202b,
title = "Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia",
abstract = "Convergent evidence from pharmacological and animal studies suggests a possible role for the synaptic vesicle glycoprotein 2A gene (SV2A) in schizophrenia susceptibility. To test systematically all common variants in the SV2A gene region for an association with schizophrenia, we used a HapMap-based haplotype tagging approach and tested five SNPs in 794 patients and 843 controls. The SNP rs15931 showed evidence for an association with schizophrenia and was followed-up in an independent sample of 2581 individuals (overall p-value=0.0042, OR=0.779). Our study in the German population provides evidence, at a genetic level, for the involvement of the SV2A gene region in schizophrenia.",
author = "Manuel Mattheisen and M{\"u}hleisen, {Thomas W} and Jana Strohmaier and Jens Treutlein and Igor Nenadic and Margrieta Alblas and Sandra Meier and Franziska Degenhardt and Stefan Herms and Per Hoffmann and Witt, {Stephanie H} and Ina Giegling and Heinrich Sauer and Schulze, {Thomas G} and Dan Rujescu and N{\"o}then, {Markus M} and Marcella Rietschel and Sven Cichon",
note = "Copyright {\textcopyright} 2012 Elsevier B.V. All rights reserved.",
year = "2012",
month = nov,
doi = "10.1016/j.schres.2012.08.027",
language = "English",
volume = "141",
pages = "262--5",
journal = "Schizophrenia research",
issn = "1573-2509",
number = "2-3",

}

RIS

TY - JOUR

T1 - Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia

AU - Mattheisen, Manuel

AU - Mühleisen, Thomas W

AU - Strohmaier, Jana

AU - Treutlein, Jens

AU - Nenadic, Igor

AU - Alblas, Margrieta

AU - Meier, Sandra

AU - Degenhardt, Franziska

AU - Herms, Stefan

AU - Hoffmann, Per

AU - Witt, Stephanie H

AU - Giegling, Ina

AU - Sauer, Heinrich

AU - Schulze, Thomas G

AU - Rujescu, Dan

AU - Nöthen, Markus M

AU - Rietschel, Marcella

AU - Cichon, Sven

N1 - Copyright © 2012 Elsevier B.V. All rights reserved.

PY - 2012/11

Y1 - 2012/11

N2 - Convergent evidence from pharmacological and animal studies suggests a possible role for the synaptic vesicle glycoprotein 2A gene (SV2A) in schizophrenia susceptibility. To test systematically all common variants in the SV2A gene region for an association with schizophrenia, we used a HapMap-based haplotype tagging approach and tested five SNPs in 794 patients and 843 controls. The SNP rs15931 showed evidence for an association with schizophrenia and was followed-up in an independent sample of 2581 individuals (overall p-value=0.0042, OR=0.779). Our study in the German population provides evidence, at a genetic level, for the involvement of the SV2A gene region in schizophrenia.

AB - Convergent evidence from pharmacological and animal studies suggests a possible role for the synaptic vesicle glycoprotein 2A gene (SV2A) in schizophrenia susceptibility. To test systematically all common variants in the SV2A gene region for an association with schizophrenia, we used a HapMap-based haplotype tagging approach and tested five SNPs in 794 patients and 843 controls. The SNP rs15931 showed evidence for an association with schizophrenia and was followed-up in an independent sample of 2581 individuals (overall p-value=0.0042, OR=0.779). Our study in the German population provides evidence, at a genetic level, for the involvement of the SV2A gene region in schizophrenia.

U2 - 10.1016/j.schres.2012.08.027

DO - 10.1016/j.schres.2012.08.027

M3 - Journal article

C2 - 23017826

VL - 141

SP - 262

EP - 265

JO - Schizophrenia research

JF - Schizophrenia research

SN - 1573-2509

IS - 2-3

ER -