Manuel Mattheisen

  1. Published

    Schizophrenia risk variants affecting microRNA function and site-specific regulation of NT5C2 by miR-206. / Hauberg, Mads Engel; Holm-Nielsen, Marie Hebsgaard; Mattheisen, Manuel; Askou, Anne Louise; Grove, Jakob; Børglum, Anders Dupont; Corydon, Thomas Juhl.

    In: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 26, No. 9, 09.2016, p. 1522-6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  2. Published

    Schizophrenia genetic variants are not associated with intelligence. / Van Scheltinga, A.F.T.; Bakker, S.C.; Van Haren, N.E.M.; Derks, E.M.; Buizer-Voskamp, J.E.; Cahn, W.; Ripke, S.; Ophoff, R.A.; Kahn, R.S.; Ripke, S.; Sanders, A.R.; Kendler, K.S.; Levinson, D.F.; Sklar, P.; Holmans, P.A.; Lin, D.-Y.; Duan, J.; Ophoff, R.A.; Andreassen, O.A.; Scolnick, E.; Cichon, S.; St Clair, D.; Corvin, A.; Gurling, H.; Werge, Thomas; Rujescu, D.; Blackwood, D.H.R.; Pato, C.N.; Malhotra, A.K.; Purcell, S.; Dudbridge, F.; Neale, B.M.; Rossin, L.; Visscher, P.M.; Posthuma, D.; Ruderfer, D.M.; Fanous, A.; Stefansson, H.; Steinberg, S.; Mowry, B.J.; Golimbet, V.; De Hert, M.; Jönsson, E.G.; Bitter, I.; Pietiläinen, O.P.H.; Collier, D.A.; Tosato, S.; Agartz, I.; Albus, M.; Alexander, M.; Amdur, R.L.; Amin, Farooq; Bass, N.; Bergen, S.E.; Black, D.W.; Børglum, A.D.; Brown, M.A.; Bruggeman, R.; Buccola, N.G.; Byerley, W.F.; Cahn, W.; Cantor, Rita M.; Carr, V.J.; Catts, S.V.; Choudhury, K.; Cloninger, C.R.; Cormican, P.; Craddock, N.; Danoy, P.A.; Datta, Suvra; De Haan, L.; Demontis, Ditte; Dikeos, D.; Djurovic, S.; Donnelly, P.; Donohoe, G.; Duong, Linh Thi Thuy; Dwyer, S.; Fink-Jensen, Anders; Freedman, R.; Freimer, N.B.; Friedl, M.; Georgieva, L.; Giegling, I.; Gill, M.; Glenthøj, Birte Yding; Godard, S.; Hamshere, M.; Hansen, M.; Hansen, T.; Hartmann, A.M.; Henskens, F.A.; Hougaard, D.M.; Hultman, C.M.; Ingason, Andrés; Jablensky, A.V.; Jakobsen, K.D.; Jay, M.; Jürgens, G.; Kahn, R.S.; Keller, M.C.; Kenis, G.; Kenny, E.; Kim, Y.; Kirov, G.K.; Konnerth, H.; Konte, B.; Krabbendam, L.; Krasucki, R.; Lasseter, V.K.; Laurent, C.; Lawrence, J.; Lencz, T.; Lerer, F.B.; Liang, K.-Y.; Lichtenstein, P.; Lieberman, J.A.; Linszen, D.H.; Lönnqvist, J.; Loughland, C.M.; Maclean, A.W.; Maher, B.S.; Maier, W.; Mallet, J.; Malloy, P.; Mattheisen, Manuel; Mattingsdal, M.; McGhee, K.A.; McGrath, J.J.; McIntosh, A.; McLean, D.E.; McQuillin, A.; Melle, I.; Michie, P.T.; Milanova, V.; Morris, D.W.; Mors, Ole; Mortensen, Preben Bo; Moskvina, V.; Muglia, P.; Myin-Germeys, I.; Nertney, D.A.; Nestadt, G.; Nielsen, J.; Nikolov, I.; Nordentoft, Merete; Norton, N.; Nöthen, M.M.; O'Dushlaine, C.T.; Olincy, A.; Olsen, L.; O'Neill, F.A.; Ørntoft, T.F.; Owen, M.J.; Pantelis, C.; Papadimitriou, G.; Pato, M.T.; Peltonen, L.; Petursson, H.; Pickard, B.; Pimm, J.; Pulver, A.E.; Puri, V.; Quested, D.; Quinn, E.M.; Rasmussen, Henrik Berg; Réthelyi, J.M.; Ribble, R.; Rietschel, M.; Riley, B.P.; Ruggeri, M.; Schall, U.; Schulze, T.G.; Schwab, S.G.; Scott, R.J.; Shi, J.; Sigurdsson, Engilbert; Silverman, J.M.; Spencer, C.C.A.; Stefansson, K.; Strange, A.; Strengman, E.; Stroup, T.S.; Suvisaari, J.; Terenius, Lars T.; Thirumalai, S.; Thygesen, J.H.; Timm, S.; Toncheva, D.; Van Den Oord, E.; Van Os, J.; Van Winkel, R.; Veldink, J.; Walsh, D.; Wang, A.G.; Wiersma, D.; Wildenauer, D.B.; Williams, H.J.; Williams, Nigel M.A.; Wormley, B.; Zammit, S.; Sullivan, Patrick F.; O'Donovan, M.C.; Daly, Mark J.; Gejman, P.V.

    In: Psychological Medicine, Vol. 43, No. 12, 2013, p. 2563-2570.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Runs of homozygosity implicate autozygosity as a schizophrenia risk factor. / Keller, Matthew C; Simonson, Matthew A; Ripke, Stephan; Neale, Ben M; Gejman, Pablo V; Howrigan, Daniel P; Lee, Sang Hong; Lencz, Todd; Levinson, Douglas F; Sullivan, Patrick F; Schizophrenia Psychiatric Genome-Wide Association Study Consortium ; Mattheisen, Manuel.

    In: PLoS genetics, Vol. 8, No. 4, 2012, p. e1002656.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Role of common and rare APP DNA sequence variants in Alzheimer disease. / Hooli, B V; Mohapatra, G; Mattheisen, Manuel; Parrado, A R; Roehr, J T; Shen, Y; Gusella, J F; Moir, R; Saunders, A J; Lange, C; Tanzi, R E; Bertram, L.

    In: Neurology Alert, Vol. 78, No. 16, 17.04.2012, p. 1250-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Risk loci for chronic obstructive pulmonary disease : a genome-wide association study and meta-analysis. / Cho, Michael H; McDonald, Merry-Lynn N; Zhou, Xiaobo; Mattheisen, Manuel; Castaldi, Peter J; Hersh, Craig P; Demeo, Dawn L; Sylvia, Jody S; Ziniti, John; Laird, Nan M; Lange, Christoph; Litonjua, Augusto A; Sparrow, David; Casaburi, Richard; Barr, R Graham; Regan, Elizabeth A; Make, Barry J; Hokanson, John E; Lutz, Sharon; Dudenkov, Tanda Murray; Farzadegan, Homayoon; Hetmanski, Jacqueline B; Tal-Singer, Ruth; Lomas, David A; Bakke, Per; Gulsvik, Amund; Crapo, James D; Silverman, Edwin K; Beaty, Terri H; NETT Genetics, ICGN, ECLIPSE and COPDGene Investigators.

    In: The Lancet Respiratory Medicine, Vol. 2, No. 3, 03.2014, p. 214-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Retraction for Dixson et al., Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain. / Dixson, Luanna; Walter, Henrik; Schneider, Michael; Erk, Susanne; Schäfer, Axel; Haddad, Leila; Grimm, Oliver; Mattheisen, Manuel; Nöthen, Markus M; Cichon, Sven; Witt, Stephanie H; Rietschel, Marcella; Mohnke, Sebastian; Seiferth, Nina; Heinz, Andreas; Tost, Heike; Meyer-Lindenberg, Andreas.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 37, 16.09.2014, p. 13582.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  7. Published

    Response to Zhu et al. / Christoforou, A.; Giddaluru, S.; Steen, V.M.; Le Hellard, S.; Mattheisen, Manuel.

    In: American Journal of Human Genetics, Vol. 91, No. 5, 02.11.2012, p. 969-970.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  8. Published

    Resequencing and follow-up of neurexin 1 (NRXN1) in schizophrenia patients. / Mühleisen, Thomas W; Basmanav, F Buket; Forstner, Andreas J; Mattheisen, Manuel; Priebe, Lutz; Herms, Stefan; Breuer, Rene; Moebus, Susanne; Nenadic, Igor; Sauer, Heinrich; Mössner, Rainald; Maier, Wolfgang; Rujescu, Dan; Ludwig, Michael; Rietschel, Marcella; Nöthen, Markus M; Cichon, Sven.

    In: Schizophrenia research, Vol. 127, No. 1-3, 04.2011, p. 35-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder : a European multicenter study. / Hammer, C; Cichon, S; Mühleisen, T W; Haenisch, B; Degenhardt, F; Mattheisen, Manuel; Breuer, R; Witt, S H; Strohmaier, J; Oruc, L; Rivas, F; Babadjanova, G; Grigoroiu-Serbanescu, M; Hauser, J; Röth, R; Rappold, G; Rietschel, M; Nöthen, M M; Niesler, B.

    In: Translational Psychiatry, Vol. 2, 2012, p. e103.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects. / Erk, Susanne; Meyer-Lindenberg, Andreas; Linden, David; Lancaster, Thomas; Mohnke, Sebastian; Grimm, Oliver; Degenhardt, Franziska; Holmans, Peter; Pocklington, Andrew; Schmierer, Phöbe; Haddad, Leila; Mühleisen, Thomas W; Mattheisen, Manuel; Witt, Stephanie H; Seiferth, Nina; Tost, Heike; Schott, Björn H; Cichon, Sven; Nöthen, Markus M; Rietschel, Marcella; Heinz, Andreas; Walter, Henrik.

    In: NeuroImage, 15.03.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Rare autosomal copy number variations in early-onset familial Alzheimer's disease. / Hooli, B V; Kovacs-Vajna, Z M; Mullin, K; Blumenthal, M A; Mattheisen, Manuel; Zhang, C; Lange, C; Mohapatra, G; Bertram, L; Tanzi, R E.

    In: Molecular Psychiatry, 11.06.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    RICOPILI : Rapid Imputation for COnsortias PIpeLIne. / Lam, Max; Awasthi, Swapnil; Watson, Hunna J.; Goldstein, Jackie; Panagiotaropoulou, Georgia; Trubetskoy, Vassily; Karlsson, Robert; Frei, Oleksander; Fan, Chun Chieh; De Witte, Ward; Mota, Nina R.; Mullins, Niamh; Brügger, Kim; Lee, S. Hong; Wray, Naomi R.; Skarabis, Nora; Huang, Hailiang; Neale, Benjamin; Daly, Mark J.; Mattheisen, Manuel; Walters, Raymond; Ripke, Stephan.

    In: Bioinformatics (Oxford, England), Vol. 36, No. 3, 2020, p. 930-933.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Quick, "imputation-free" meta-analysis with proxy-SNPs. / Meesters, Christian; Leber, Markus; Herold, Christine; Angisch, Marina; Mattheisen, Manuel; Drichel, Dmitriy; Lacour, André; Becker, Tim.

    In: B M C Bioinformatics, Vol. 13, 2012, p. 231.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder. / Trzaskowski, Maciej; Mehta, Divya; Peyrot, Wouter J.; Hawkes, David; Davies, Daniel; Howard, David M.; Kemper, Kathryn E.; Sidorenko, Julia; Maier, Robert; Ripke, Stephan; Mattheisen, Manuel; Baune, Bernhard T.; Grabe, Hans J.; Heath, Andrew C.; Jones, Lisa; Jones, Ian; Madden, Pamela A. F.; McIntosh, Andrew M.; Breen, Gerome; Lewis, Cathryn M.; Borglum, Anders D.; Sullivan, Patrick F.; Martin, Nicholas G.; Kendler, Kenneth S.; Levinson, Douglas F.; Wray, Naomi R.; Major Depress Disorder Working G.

    In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, Vol. 180, No. 6, 09.2019, p. 439-447.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Publisher Correction : Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. / GERAD1 Consortium:.

    In: Nature Genetics, Vol. 51, No. 7, 07.2019, p. 1193-1193.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  16. Published

    Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. / O'Dushlaine, Colm; Rossin, Lizzy; Lee, Phil H.; Duncan, Laramie; Parikshak, Neelroop N.; Newhouse, Stephen; Ripke, Stephan; Neale, Benjamin M.; Purcell, Shaun M.; Posthuma, Danielle; Nurnberger, John I.; Lee, S. Hong; Faraone, Stephen V.; Perlis, Roy H.; Mowry, Bryan J.; Thapar, Anita; Goddard, Michael E.; Witte, John S.; Absher, Devin; Agartz, Ingrid; Akil, Huda; Amin, Farooq; Andreassen, Ole A.; Anjorin, Adebayo; Anney, Richard; Anttila, Verneri; Arking, Dan E.; Asherson, Philip; Azevedo, Maria H.; Backlund, Lena; Badner, Judith A.; Bailey, Anthony J.; Banaschewski, Tobias; Barchas, Jack D.; Barnes, Michael R.; Barrett, Thomas B.; Bass, Nicholas; Battaglia, Agatino; Bauer, Michael; Bayes, Monica; Bellivier, Frank; Bergen, Sarah E.; Berrettini, Wade; Betancur, Catalina; Bettecken, Thomas; Biederman, Joseph; Binder, Elisabeth B.; Black, Donald W.; Mattheisen, Manuel; Meier, Sandra; IIBDGC; Network & Pathway Anal Subgrp Psyc.

    In: Nature Neuroscience, Vol. 18, No. 2, 02.2015, p. 199-209.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. / Le Hellard, S; Mühleisen, T W; Djurovic, S; Fernø, J; Ouriaghi, Z; Mattheisen, Manuel; Vasilescu, C; Raeder, M B; Hansen, T; Strohmaier, J; Georgi, A; Brockschmidt, F F; Melle, I; Nenadic, I; Sauer, H; Rietschel, M; Nöthen, M M; Werge, T; Andreassen, O A; Cichon, S; Steen, V M.

    In: Molecular Psychiatry, Vol. 15, No. 5, 05.2010, p. 463-72.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD. / Guo, W.; Samuels, J. F.; Wang, Y.; Cao, H.; Ritter, M.; Nestadt, P. S.; Krasnow, J.; Greenberg, B. D.; Fyer, A. J.; McCracken, J. T.; Geller, D. A.; Murphy, D. L.; Knowles, J. A.; Grados, M. A.; Riddle, M. A.; Rasmussen, S. A.; McLaughlin, N. C.; Nurmi, E. L.; Askland, K. D.; Culten, B. A.; Piacentini, J.; Pauls, D. L.; Bienvenu, O. J.; Stewart, S. E.; Goes, F. S.; Maher, B.; Pulver, A. E.; Valle, D.; Mattheisen, M.; Qian, J.; Nestad, G.; Shugart, Y. Y.

    In: European Neuropsychopharmacology, Vol. 27, No. 7, 07.2017, p. 657-666.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia : A Danish Population-Based Study and Meta-analysis. / Agerbo, Esben; Sullivan, Patrick F; Vilhjálmsson, Bjarni J; Pedersen, Carsten B; Mors, Ole; Børglum, Anders D; Hougaard, David M; Hollegaard, Mads V; Meier, Sandra; Mattheisen, Manuel; Ripke, Stephan; Wray, Naomi R; Mortensen, Preben B.

    In: J A M A Psychiatry, 07.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis. / Strom, Nora I.; Grove, Jakob; Meier, Sandra M.; Bækvad-Hansen, Marie; Becker Nissen, Judith; Damm Als, Thomas; Halvorsen, Matthew; Nordentoft, Merete; Mortensen, Preben B.; Hougaard, David M.; Werge, Thomas; Mors, Ole; Børglum, Anders D.; Crowley, James J.; Bybjerg-Grauholm, Jonas; Mattheisen, Manuel.

    In: Frontiers in Genetics, Vol. 12, 711624, 08.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease. / Hobbs, Brian D; Foreman, Marilyn G; Bowler, Russell; Jacobson, Francine; Make, Barry J; Castaldi, Peter J; San José Estépar, Raúl; Silverman, Edwin K; Hersh, Craig P; COPDGene Investigators ; Mattheisen, Manuel.

    In: American Thoracic Society. Annals (Online), Vol. 11, No. 9, 11.2014, p. 1387-94.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. / Lee, Jin Hwa; Cho, Michael H; McDonald, Merry-Lynn N; Hersh, Craig P; Castaldi, Peter J; Crapo, James D; Wan, Emily S; Dy, Jennifer G; Chang, Yale; Regan, Elizabeth A; Hardin, Megan; DeMeo, Dawn L; Silverman, Edwin K; COPDGene Investigators ; Mattheisen, Manuel.

    In: Kokyuukika, Vol. 108, No. 10, 10.2014, p. 1469-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. / Gusev, Alexander; Lee, S Hong; Trynka, Gosia; Finucane, Hilary; Vilhjálmsson, Bjarni Jóhann; Xu, Han; Zang, Chongzhi; Ripke, Stephan; Bulik-Sullivan, Brendan; Stahl, Eli; Kähler, Anna K; Hultman, Christina M; Purcell, Shaun M; McCarroll, Steven A; Daly, Mark; Pasaniuc, Bogdan; Sullivan, Patrick F; Neale, Benjamin M; Wray, Naomi R; Raychaudhuri, Soumya; Price, Alkes L; Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members).

    In: American Journal of Human Genetics, Vol. 95, No. 5, 2014, p. 535-52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. / Fullard, John F.; Giambartolomei, Claudia; Hauberg, Mads E.; Xu, Ke; Voloudakis, Georgios; Shao, Zhiping; Bare, Christopher; Dudley, Joel T.; Mattheisen, Manuel; Robakis, Nikolaos K.; Haroutunian, Vahram; Roussos, Panos.

    In: Human Molecular Genetics, Vol. 26, No. 10, 15.05.2017, p. 1942-1951.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    On Association Analysis of Rare Variants Under Population Substructure : An Approach for the Detection of Subjects That Can Cause Bias in the Analysis-Topt : An Outlier Detection Method. / Qiao, Dandi; Mattheisen, Manuel; Lange, Christoph.

    In: Genetic Epidemiology, 14.05.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review