Mai Marie Holm

  1. Journal article
  2. Published

    Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam. / Andreasen, Signe Rode; Lundbye, Camilla Johanne; Christensen, Tine Breckling; Thielsen, Karina Dvinge; Schmitt-John, Thomas; Holm, Mai Marie.

    In: Neuroscience Letters, 18.08.2017, p. 85-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologues of AMPA. / Brehm, Lotte; Greenwood, Jeremy R.; Sløk, Frank; Holm, Mai Marie; Nielsen, Birgitte; Geneser, Ulla; Stensbøl, Tine B.; Bräuner-Osborne, Hans; Begtrup, Mikael; Jensen, Jan Egebjerg; Krogsgaard-Larsen, Povl.

    In: Chirality, 2004, p. 452-466.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Sortilin-Related Receptor SORCS3 Is a Postsynaptic Modulator of Synaptic Depression and Fear Extinction. / Breiderhoff, Tilman; Christiansen, Gitte B; Pallesen, Lone T; Vægter, Christian Bjerggaard; Nykjaer, Anders; Holm, Mai Marie; Glerup, Simon; Willnow, Thomas E.

    In: PLOS ONE, Vol. 8, No. 9, 2013, p. e75006.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures. / Bundgaard Christiansen, Gitte; Harbak, Barbara; E. Hede, Susanne; H. Gouliaev, Alex; Olsen, Lars; Frydenvang, Karla; Jensen, Jan Egebjerg; Sandholm Kastrup, Jette; Holm, Mai Marie.

    In: Neuroscience, Vol. 310, 2015, p. 709.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The sorting receptor SorCS3 is a stronger regulator of glutamate receptor functions compared to GABAergic mechanisms in the hippocampus. / Bundgaard Christiansen, Gitte; Andersen, Katrine; Riis, Sarah; Nykjær, Anders; Bølcho, Ulrik; Jensen, Morten Skovgaard; Holm, Mai Marie.

    In: The Hippocampus, 13.02.2017, p. 235-248.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia. / Clarkson, Andrew N; Boothman-Burrell, Lily; Dósa, Zita; Nagaraja, Raghavendra Y; Jin, Liang; Parker, Kim ; van Nieuwenhuijzen, Petra S; Neumann, Silke; Gowing, Emma K; Gavande, Navnath; Ahring, Philip K; Holm, Mai Marie; Hanrahan, Jane R; Nicolazzo, Joseph A; Jensen, Kimmo; Chebib, Mary.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 39, No. 7, 07.2019, p. 1266-1282.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

     Mapping of the spontaneous deletion in the Ap3d1 gene of mocha mice: fast and reliable genotyping. / Drasbek, Kim Ryun; Holm, Mai Marie; Delenclos, Marion; Jensen, Kimmo.

    In: BMC Research Notes, Vol. 1, No. 119, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: Synthesis, modelling and molecular pharmacology. / Frølund, B.; Greenwood, J.R.; Holm, Mai Marie; Jensen, Jan Egebjerg; Madsen, U.; Nielsen, B.; Bräuner-Osborne, H.; Stensbøl, T.B.; Krogsgaard-Larsen, P.

    In: Bioorg. Med. Chem., Vol. 13, 2005, p. 5391-5398.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    SorCS2 is required for BDNF-dependent plasticity in the hippocampus. / Glerup, S; Bolcho, U; Bøggild, S; Vaegter, C B; Smith, A H; Nieto-Gonzalez, J L; Ovesen, P L; Pedersen, L F; Fjorback, A N; Kjolby, Mads; Login, H; Holm, M M; Andersen, O M; Nyengaard, J R; Willnow, T E; Jensen, K; Nykjaer, A; Jensen, Simon Mølgaard.

    In: Molecular Psychiatry, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    A bindingsite tyrosine shapes desensitization and agonist potency at the AMPA receptor GluR2: A mutagenic, kinetic and crystallographic study. / Holm, Mai Marie; Naur, P.; Vestergaard, B.; Geballe, M.T.; Gajhede, M.; Kastrup, J.S.; Traynelis, S.F.; Jensen, Jan Egebjerg.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 35469-35476.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Hippocampal GABAergic dysfunction in a rat chronic mild stress model of depression. / Holm, Mai Marie; Nieto-Gonzalez, Jose Luis; Vardya, Irina; Henningsen, Kim; Jayatissa, Magdalena Niepsuj; Wiborg, Ove; Jensen, Kimmo.

    In: The Hippocampus, Vol. 21, 2011, p. 422-433.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Accepted/In press

    Insulin as a potent bidirectional regulator of GABAergic signaling in the hippocampus of an Alzheimer’s disease mouse model. / Holm, Mai Marie.

    In: Acta Physiologica, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus. / Holm, Mai Marie; Nieto-Gonzales, Jose Luis; Vardya, Irina; Vægter, Christian Bjerggaard; Nykjær, Anders; Jensen, Kimmo.

    In: Journal of Neuroscience, Vol. 29, No. 40, 2009, p. 12412-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2. / Holm, Mai Marie; Lunn, M.L.; Traynelis, S.F.; Kastrup, J.S.; Jensen, Jan Egebjerg.

    In: Proc. Natl. Acad. Sci., Vol. 102, 2005, p. 12053-12058.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Kinetic analysis of evoked IPSCs discloses mechanism of antagonism of synaptic GABAA receptors by picrotoxin. / Korshoej, A R; Holm, M M; Jensen, K; Lambert, J D C.

    In: British Journal of Pharmacology, Vol. 159, No. 3, 01.02.2010, p. 636-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Kinetic analysis of evoked IPSCs discloses mechanism of antagonism of synaptic GABAA receptors by picrotoxin. / Korshøj, Anders Rosendahl; Holm, Mai Marie; Jensen, Kimmo; Lambert, John D. C.

    In: British Journal of Pharmacology, Vol. 159, 2010, p. 636-649.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741. / Nielsen(Holm), Mai Marie; Krogsgaard-Larsen, Povl; Liljefors, Tommy; Egebjerg, Jan.

    In: Molecular Pharmacology, Vol. 63, 2003, p. 19-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Presynaptic Plasticity as a Hallmark of Rat Stress Susceptibility and Antidepressant Response. / Nieto-Gonzalez, Jose Luis; Holm, Mai Marie; Vardya, Irina; Christensen, Trine; Wiborg, Ove; Jensen, Kimmo.

    In: P L o S One, Vol. 10, No. 3, 05.03.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments. / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Morten Skovgaard; Jensen, Kimmo; Holm, Mai Marie.

    In: P L o S One, Vol. 8(12), No. e82767, 11.12.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. E-pub ahead of print

    Positive modulation of delta-subunit containing GABAA receptors in mouse neurons. / Vardya, Irina; Hoestgaard-Jensen, Kirsten; Nieto-Gonzalez, Jose Luis; Boddum, Kim; Dósa, Zita; Holm, Mai Marie; Wolinsky, T; Jones, K; Dalby, NO; Ebert, B; Jensen, Kimmo.

    In: Neuropharmacology, Vol. 63, No. 3, 2012, p. 469-79.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Ph.D. thesis
  23. Published

    Structure-Function Studies of AMPA and Kainate Receptors. / Holm, Mai Marie.

    2004.

    Research output: Book/anthology/dissertation/reportPh.D. thesis

  24. Book chapter
  25. Published

    Plasticitet og cellulær indlæring i hippocampus. / Holm, Mai Marie; Jensen, Kimmo.

    Den plastiske hjerne. HjerneForum, 2011. p. 25-33.

    Research output: Contribution to book/anthology/report/proceedingBook chapterCommunication

  26. Poster
  27. Published

    Influence of GABA and GHB on intracellular calcium levels in cultured cortical mouse neurons. / Boddum, Kim; Holm, Mai Marie; Hoestgaard-Jensen, Kirsten; Jensen, Kimmo.

    2009. Poster session presented at SPS2009 (The Scandinavian Physiological Society), Uppsala, Sweden.

    Research output: Contribution to conferencePosterResearch

  28. Published

    Desensitization of Recombinant AMPA Receptors, Role of Molecular Pharmacology. / Hede, Susanne E.; Nielsen(Holm), Mai Marie; Guliaev, Alex H.; Varming, Thomas; Egebjerg, Jan.

    2007. Poster session presented at Biophysics, 2002 (Biophysical Journal, 82 (1) 1240), San Francisco, United States.

    Research output: Contribution to conferencePosterResearch

  29. Published

    Presynaptic plasticity as a hallmark of rat stress susceptibility and antidepressant response. / Holm, Mai Marie; Nieto-Gonzalez, Jose Luis; Vardya, Irina; Christensen, Trine; Wiborg, Ove; Jensen, Kimmo.

    2011. Poster session presented at Dansk Psykiatrisk Selskabs Årsmøde 2011, Nyborg, Denmark.

    Research output: Contribution to conferencePosterResearch

  30. Published

    Single axon fiber stimulation in rat hippocampus: Effects of the plant convulsant, picrotoxin, on IPSC amplitude and decay kinetics. / Holm, Mai Marie; Korshøj, Anders Rosendahl; Lambert, John D. C.; Jensen, Kimmo.

    2007. Poster session presented at Neuroscience 2007, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  31. Published

    Blockade of GABAergic IPSCs in cultured hippocampal neurones by picrotoxin: Kinetic analysis provides insight into mechanism. / Korshøj, Anders Rosendahl; Holm, Mai Marie; Jensen, Kimmo; Lambert, John D. C.

    2007. Poster session presented at Neuroscience 2007, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  32. Published

    Comparison of Functional Activity and Structural Binding Modes of Selected AMPA Analogues Complexed With a Recombinant AMPA Receptor Subunit. / Lunn, Marie-Louise; Nielsen(Holm), Mai Marie; Hogner, Anders; Krogsgaard-Larsen, Povl; Kastrup, Jette Sandholm; Egebjerg, Jan.

    2007. Poster session presented at Neuroscience 2001, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  33. Published

    Electrophysiological and structural analyses in the hippocampus of the wobbler mouse model of ALS. / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Kimmo; Holm, Mai Marie.

    2012. Poster session presented at Synaptic wiring specificity and network dynamics in the brain, The Brain Prize and DSfN, Sønderborg, Denmark.

    Research output: Contribution to conferencePosterResearch

  34. Published

    Hippocampal Hyperexcitability and a Reduced Number of Parvalbumin Positive Interneurons in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS). / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Morten Skovgaard; Jensen, Kimmo; Holm, Mai Marie.

    2013. Poster session presented at SFN annual meeting, 2013, San Diego, CA, United States.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Hyperexcitability and a Reduced Number of Interneurons in the Wobbler Mouse Model of ALS. / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Morten Skovgaard; Jensen, Kimmo; Holm, Mai Marie.

    2013. Poster session presented at The Brain Prize Meeting 2013, MIddelfart, Denmark.

    Research output: Contribution to conferencePosterResearch

  36. Published

    Increased synaptic GABAergic inhibition in dentate gyrus of mice deficient of sortilin. Joint meeting of the Scandinavian and German Physiological Societies Mar. 27 2010 - Mar. 30 2010 Copenhagen, Denmark. / Vardya, Irina; Holm, Mai Marie; Dósa, Zita; Nieto-Gonzalez, Jose Luis; Nykjær, Anders; Jensen, Kimmo.

    2010. Poster session presented at Joint meeting of the Scandinavian and German Physiological Societies, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  37. Conference abstract for conference
  38. Published

    Getting closer to the function of the postsynaptic receptor SORCS3 in synaptic transmission and synaptic plasticity. / Bundgaard Christiansen, Gitte; Breiderhoff, Tilman; Nykjær, Anders; Jensen, Kimmo; Willnow, Thomas; Holm, Mai Marie.

    2014. Abstract from 9th FENS forum of neuroscience , Milan, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  39. Published

    Effect of prenatal corticosteroid exposure on the GABAergic inhibition in rat hippocampus. / Dósa, Zita; Nieto-Gonzales, Jose Luis; Hougaard, Karin Sørig; Holm, Mai Marie; Wegener, Gregers; Jensen, Kimmo.

    2011. Abstract from The Brain Prize Meeting, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  40. Published

    Stress-susceptibility and resilience can be distinguished by hippocampal electrophysiological analysis in a chronic mild stress rat model of depression. / Holm, Mai Marie; Nieto-Gonzales, Jose Luis; Vardya, Irina; Christensen, Trine; Wiborg, Ove; Jensen, Kimmo.

    2011. Abstract from The Brain Prize Meeting, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  41. Published

    Abstract from The Brain Prize Meeting, Aarhus, Danmark. / Jensen, Kimmo; Wegener, Gregers; Holm, Mai Marie; Hougaard, Karin Sørig; Nieto-Gonzales, Jose Luis; Dósa, Zita.

    2011.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  42. Review
  43. Published

    Insights from Structure-Function Studies of AMPA Receptor Agonists and Antagonists. / Holm, Mai Marie; Jensen, Kimmo; Egebjerg, Jan.

    Amino Acids Receptor Research. New York : Nova Science Publishers, 2008. p. 99-123.

    Research output: Contribution to book/anthology/report/proceedingReviewResearch