Mai Marie Holm

  1. 2019
  2. Published

    The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia. / Clarkson, Andrew N; Boothman-Burrell, Lily; Dósa, Zita; Nagaraja, Raghavendra Y; Jin, Liang; Parker, Kim ; van Nieuwenhuijzen, Petra S; Neumann, Silke; Gowing, Emma K; Gavande, Navnath; Ahring, Philip K; Holm, Mai Marie; Hanrahan, Jane R; Nicolazzo, Joseph A; Jensen, Kimmo; Chebib, Mary.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 39, No. 7, 07.2019, p. 1266-1282.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2017
  4. Published

    Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam. / Andreasen, Signe Rode; Lundbye, Camilla Johanne; Christensen, Tine Breckling; Thielsen, Karina Dvinge; Schmitt-John, Thomas; Holm, Mai Marie.

    In: Neuroscience Letters, 18.08.2017, p. 85-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    The sorting receptor SorCS3 is a stronger regulator of glutamate receptor functions compared to GABAergic mechanisms in the hippocampus. / Bundgaard Christiansen, Gitte; Andersen, Katrine; Riis, Sarah; Nykjær, Anders; Bølcho, Ulrik; Jensen, Morten Skovgaard; Holm, Mai Marie.

    In: The Hippocampus, 13.02.2017, p. 235-248.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2016
  7. Published

    SorCS2 is required for BDNF-dependent plasticity in the hippocampus. / Glerup, S; Bolcho, U; Bøggild, S; Vaegter, C B; Smith, A H; Nieto-Gonzalez, J L; Ovesen, P L; Pedersen, L F; Fjorback, A N; Kjolby, Mads; Login, H; Holm, M M; Andersen, O M; Nyengaard, J R; Willnow, T E; Jensen, K; Nykjaer, A; Jensen, Simon Mølgaard.

    In: Molecular Psychiatry, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2015
  9. Published

    Presynaptic Plasticity as a Hallmark of Rat Stress Susceptibility and Antidepressant Response. / Nieto-Gonzalez, Jose Luis; Holm, Mai Marie; Vardya, Irina; Christensen, Trine; Wiborg, Ove; Jensen, Kimmo.

    In: P L o S One, Vol. 10, No. 3, 05.03.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures. / Bundgaard Christiansen, Gitte; Harbak, Barbara; E. Hede, Susanne; H. Gouliaev, Alex; Olsen, Lars; Frydenvang, Karla; Jensen, Jan Egebjerg; Sandholm Kastrup, Jette; Holm, Mai Marie.

    In: Neuroscience, Vol. 310, 2015, p. 709.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. 2014
  12. Published

    Getting closer to the function of the postsynaptic receptor SORCS3 in synaptic transmission and synaptic plasticity. / Bundgaard Christiansen, Gitte; Breiderhoff, Tilman; Nykjær, Anders; Jensen, Kimmo; Willnow, Thomas; Holm, Mai Marie.

    2014. Abstract from 9th FENS forum of neuroscience , Milan, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  13. 2013
  14. Published

    The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments. / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Morten Skovgaard; Jensen, Kimmo; Holm, Mai Marie.

    In: P L o S One, Vol. 8(12), No. e82767, 11.12.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Hippocampal Hyperexcitability and a Reduced Number of Parvalbumin Positive Interneurons in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS). / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Morten Skovgaard; Jensen, Kimmo; Holm, Mai Marie.

    2013. Poster session presented at SFN annual meeting, 2013, San Diego, CA, United States.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Hyperexcitability and a Reduced Number of Interneurons in the Wobbler Mouse Model of ALS. / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Morten Skovgaard; Jensen, Kimmo; Holm, Mai Marie.

    2013. Poster session presented at The Brain Prize Meeting 2013, MIddelfart, Denmark.

    Research output: Contribution to conferencePosterResearch

  17. Published

    Sortilin-Related Receptor SORCS3 Is a Postsynaptic Modulator of Synaptic Depression and Fear Extinction. / Breiderhoff, Tilman; Christiansen, Gitte B; Pallesen, Lone T; Vægter, Christian Bjerggaard; Nykjaer, Anders; Holm, Mai Marie; Glerup, Simon; Willnow, Thomas E.

    In: PLOS ONE, Vol. 8, No. 9, 2013, p. e75006.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2012
  19. Published

    Electrophysiological and structural analyses in the hippocampus of the wobbler mouse model of ALS. / Thielsen, Karina Dvinge; Moser, Jakob Maximilian; Schmitt-John, Thomas; Jensen, Kimmo; Holm, Mai Marie.

    2012. Poster session presented at Synaptic wiring specificity and network dynamics in the brain, The Brain Prize and DSfN, Sønderborg, Denmark.

    Research output: Contribution to conferencePosterResearch

  20. E-pub ahead of print

    Positive modulation of delta-subunit containing GABAA receptors in mouse neurons. / Vardya, Irina; Hoestgaard-Jensen, Kirsten; Nieto-Gonzalez, Jose Luis; Boddum, Kim; Dósa, Zita; Holm, Mai Marie; Wolinsky, T; Jones, K; Dalby, NO; Ebert, B; Jensen, Kimmo.

    In: Neuropharmacology, Vol. 63, No. 3, 2012, p. 469-79.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. 2011
  22. Published

    Abstract from The Brain Prize Meeting, Aarhus, Danmark. / Jensen, Kimmo; Wegener, Gregers; Holm, Mai Marie; Hougaard, Karin Sørig; Nieto-Gonzales, Jose Luis; Dósa, Zita.

    2011.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  23. Published

    Effect of prenatal corticosteroid exposure on the GABAergic inhibition in rat hippocampus. / Dósa, Zita; Nieto-Gonzales, Jose Luis; Hougaard, Karin Sørig; Holm, Mai Marie; Wegener, Gregers; Jensen, Kimmo.

    2011. Abstract from The Brain Prize Meeting, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  24. Published

    Hippocampal GABAergic dysfunction in a rat chronic mild stress model of depression. / Holm, Mai Marie; Nieto-Gonzalez, Jose Luis; Vardya, Irina; Henningsen, Kim; Jayatissa, Magdalena Niepsuj; Wiborg, Ove; Jensen, Kimmo.

    In: The Hippocampus, Vol. 21, 2011, p. 422-433.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Plasticitet og cellulær indlæring i hippocampus. / Holm, Mai Marie; Jensen, Kimmo.

    Den plastiske hjerne. HjerneForum, 2011. p. 25-33.

    Research output: Contribution to book/anthology/report/proceedingBook chapterCommunication

  26. Published

    Presynaptic plasticity as a hallmark of rat stress susceptibility and antidepressant response. / Holm, Mai Marie; Nieto-Gonzalez, Jose Luis; Vardya, Irina; Christensen, Trine; Wiborg, Ove; Jensen, Kimmo.

    2011. Poster session presented at Dansk Psykiatrisk Selskabs Årsmøde 2011, Nyborg, Denmark.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Stress-susceptibility and resilience can be distinguished by hippocampal electrophysiological analysis in a chronic mild stress rat model of depression. / Holm, Mai Marie; Nieto-Gonzales, Jose Luis; Vardya, Irina; Christensen, Trine; Wiborg, Ove; Jensen, Kimmo.

    2011. Abstract from The Brain Prize Meeting, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  28. 2010
  29. Published

    Kinetic analysis of evoked IPSCs discloses mechanism of antagonism of synaptic GABAA receptors by picrotoxin. / Korshoej, A R; Holm, M M; Jensen, K; Lambert, J D C.

    In: British Journal of Pharmacology, Vol. 159, No. 3, 01.02.2010, p. 636-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Increased synaptic GABAergic inhibition in dentate gyrus of mice deficient of sortilin. Joint meeting of the Scandinavian and German Physiological Societies Mar. 27 2010 - Mar. 30 2010 Copenhagen, Denmark. / Vardya, Irina; Holm, Mai Marie; Dósa, Zita; Nieto-Gonzalez, Jose Luis; Nykjær, Anders; Jensen, Kimmo.

    2010. Poster session presented at Joint meeting of the Scandinavian and German Physiological Societies, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  31. Published

    Kinetic analysis of evoked IPSCs discloses mechanism of antagonism of synaptic GABAA receptors by picrotoxin. / Korshøj, Anders Rosendahl; Holm, Mai Marie; Jensen, Kimmo; Lambert, John D. C.

    In: British Journal of Pharmacology, Vol. 159, 2010, p. 636-649.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. 2009
  33. Published

    Influence of GABA and GHB on intracellular calcium levels in cultured cortical mouse neurons. / Boddum, Kim; Holm, Mai Marie; Hoestgaard-Jensen, Kirsten; Jensen, Kimmo.

    2009. Poster session presented at SPS2009 (The Scandinavian Physiological Society), Uppsala, Sweden.

    Research output: Contribution to conferencePosterResearch

  34. Published

    Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus. / Holm, Mai Marie; Nieto-Gonzales, Jose Luis; Vardya, Irina; Vægter, Christian Bjerggaard; Nykjær, Anders; Jensen, Kimmo.

    In: Journal of Neuroscience, Vol. 29, No. 40, 2009, p. 12412-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. 2008
  36. Published

    Insights from Structure-Function Studies of AMPA Receptor Agonists and Antagonists. / Holm, Mai Marie; Jensen, Kimmo; Egebjerg, Jan.

    Amino Acids Receptor Research. New York : Nova Science Publishers, 2008. p. 99-123.

    Research output: Contribution to book/anthology/report/proceedingReviewResearch

  37. Published

     Mapping of the spontaneous deletion in the Ap3d1 gene of mocha mice: fast and reliable genotyping. / Drasbek, Kim Ryun; Holm, Mai Marie; Delenclos, Marion; Jensen, Kimmo.

    In: BMC Research Notes, Vol. 1, No. 119, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2007
  39. Published

    Blockade of GABAergic IPSCs in cultured hippocampal neurones by picrotoxin: Kinetic analysis provides insight into mechanism. / Korshøj, Anders Rosendahl; Holm, Mai Marie; Jensen, Kimmo; Lambert, John D. C.

    2007. Poster session presented at Neuroscience 2007, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  40. Published

    Comparison of Functional Activity and Structural Binding Modes of Selected AMPA Analogues Complexed With a Recombinant AMPA Receptor Subunit. / Lunn, Marie-Louise; Nielsen(Holm), Mai Marie; Hogner, Anders; Krogsgaard-Larsen, Povl; Kastrup, Jette Sandholm; Egebjerg, Jan.

    2007. Poster session presented at Neuroscience 2001, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  41. Published

    Desensitization of Recombinant AMPA Receptors, Role of Molecular Pharmacology. / Hede, Susanne E.; Nielsen(Holm), Mai Marie; Guliaev, Alex H.; Varming, Thomas; Egebjerg, Jan.

    2007. Poster session presented at Biophysics, 2002 (Biophysical Journal, 82 (1) 1240), San Francisco, United States.

    Research output: Contribution to conferencePosterResearch

  42. Published

    Single axon fiber stimulation in rat hippocampus: Effects of the plant convulsant, picrotoxin, on IPSC amplitude and decay kinetics. / Holm, Mai Marie; Korshøj, Anders Rosendahl; Lambert, John D. C.; Jensen, Kimmo.

    2007. Poster session presented at Neuroscience 2007, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  43. 2005
  44. Published

    A bindingsite tyrosine shapes desensitization and agonist potency at the AMPA receptor GluR2: A mutagenic, kinetic and crystallographic study. / Holm, Mai Marie; Naur, P.; Vestergaard, B.; Geballe, M.T.; Gajhede, M.; Kastrup, J.S.; Traynelis, S.F.; Jensen, Jan Egebjerg.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 35469-35476.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2. / Holm, Mai Marie; Lunn, M.L.; Traynelis, S.F.; Kastrup, J.S.; Jensen, Jan Egebjerg.

    In: Proc. Natl. Acad. Sci., Vol. 102, 2005, p. 12053-12058.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: Synthesis, modelling and molecular pharmacology. / Frølund, B.; Greenwood, J.R.; Holm, Mai Marie; Jensen, Jan Egebjerg; Madsen, U.; Nielsen, B.; Bräuner-Osborne, H.; Stensbøl, T.B.; Krogsgaard-Larsen, P.

    In: Bioorg. Med. Chem., Vol. 13, 2005, p. 5391-5398.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. 2004
  48. Published

    Structure-Function Studies of AMPA and Kainate Receptors. / Holm, Mai Marie.

    2004.

    Research output: Book/anthology/dissertation/reportPh.D. thesis

  49. Published

    Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologues of AMPA. / Brehm, Lotte; Greenwood, Jeremy R.; Sløk, Frank; Holm, Mai Marie; Nielsen, Birgitte; Geneser, Ulla; Stensbøl, Tine B.; Bräuner-Osborne, Hans; Begtrup, Mikael; Jensen, Jan Egebjerg; Krogsgaard-Larsen, Povl.

    In: Chirality, 2004, p. 452-466.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. 2003
  51. Published

    The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741. / Nielsen(Holm), Mai Marie; Krogsgaard-Larsen, Povl; Liljefors, Tommy; Egebjerg, Jan.

    In: Molecular Pharmacology, Vol. 63, 2003, p. 19-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review