Projects per year
Personal profile
Research
The Danish Mole Project - Genetics in trophoblastic disease
A hydatidiform mole (HM) is an abnormal conceptus, with a surplus of paternally interited genes. A HM cause a significant risk of trophoblastic neoplasia.
We have shown that the risk of cancer is low after triploid HMs - and the international guidelines were changed.
Now we test if
- zygosity and the proteome can predict the prognosis
- the women can have personalized follow-up by using the genetic profile of the HM
Profile
As an external associate professor, I conduct research in genertics in relation to early differentiation and cancer. In am the head of the Danish Mole project.
I am also interested in medical education from the students start at the university to doctors specialized in clinical genetics struggle with “continuous education”.
I am a MD, PhD and specialist in clinical genetics.
Job responsibilities
Resarch
Teaching and examination of medical students
Education/Academic qualification
Medicine, MD, Aarhus University (AU)
Award Date: 12 Jun 1991
External positions
Consultant, Aarhus University (AU)
1 Mar 2012 → …
Keywords
- Genetics
- Pregnancy
- Cancer
- Kidneys and urinary tract
- Learning in work life
Areas of expertise
- Genetics
- Cancer
- Embryology
- Medical education
- Communication
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mapping imprinted genes relevant for early differentiation
Sunde, L. (Participant), Niemann, I. (Participant), Bolund, L. (Participant) & Lund, H. (Participant)
01/01/2005 → …
Project: Research
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The Danish Mole Project
Sunde, L. (Participant), Bolund, L. (Participant), Niemann, I. (Participant), Fisher, R. A. (Collaborator) & Slim, R. (Participant)
01/04/1986 → …
Project: Research
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Hydatidiform mole: Correlation between the macroscopic phenotype, the ploidy, and the clinical outcome
Sunde, L. (Participant), Niemann, I. (Participant) & Bolund, L. (Participant)
31/03/1986 → …
Project: Research
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Y-LAB: Fetal cells as diagnostic tools for trophoblastic diseases
Sunde, L. (Project manager), Uldbjerg, N. (Participant), Schelde, P. (Participant), Hatt, L. (Participant), Singh, R. (Participant), Ravn, K. (Participant) & Baasch Christensen, I. (Participant)
18/05/2019 → 16/05/2020
Project: Research
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Colorectal carcinogenesis in the Lynch syndromes and familial adenomatous polyposis: trigger events and downstream consequences
Møller, P., Ahadova, A., Kloor, M., Seppälä, T. T., Burn, J., Haupt, S., Macrae, F., Dominguez-Valentin, M., Möslein, G., Lindblom, A., sunde, L., Winship, I., Capella, G., Monahan, K., Buchanan, D. D., Evans, D. G., Hovig, E. & Sampson, J. R., Dec 2025, In: Hereditary Cancer in Clinical Practice. 23, 1, 3.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Open Access1 Citation (Scopus) -
Genetik i føtalmedicin
Translated title of the contribution :Genetics in fetal medicine Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research
Open Access1 Citation (Scopus) -
Practical Guidelines for the Treatment of Gestational Trophoblastic Disease: Collaboration of the European Organisation for the Treatment of Trophoblastic Disease (EOTTD)-European Society of Gynaecologic Oncology (ESGO)-Gynecologic Cancer InterGroup (GCIG)-International Society for the Study of Trophoblastic Diseases (ISSTD)
Lok, C., Braicu, E. I., Planchamp, F., Berkowitz, R., Seckl, M. & EOTTD-ESGO-GCIG-ISSTD Guideline Committee, 20 Jun 2025, In: Journal of Clinical Oncology. 43, 18, p. 2119-2128 10 p., JCO-24-02326.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
8 Citations (Scopus) -
Whole Genome Sequencing in Prenatal Diagnostics: The Danish Approach to Guideline Formation and Implementation Within Public Healthcare
Vogel, I., Andreasen, L., Balslev-Harder, M., Becher, N., Ernst, A., Gadsbøll, K., Hjortshøj, T. D., Hvidbjerg, M. S., Larsen, M., Lou, S., Bay Lund, I. C., Pedersen, L. H., Sønderberg Roos, L. K., Sperling, L., Sunde, L., Tørring, P. M., Vedel, C. & Petersen, O. B., 23 Mar 2025, (E-pub / Early view) In: Prenatal Diagnosis.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Aneuploidy is frequent in heterozygous diploid and triploid hydatidiform moles
Walbum, P., Andreasen, L., Geilswijk, M., Niemann, I. & Sunde, L., Mar 2024, In: Scientific Reports. 14, 1, 6876.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access2 Citations (Scopus)