Lotte Bonde Bertelsen

  1. 2019
  2. Published
  3. Published

    Metabolic consequences of lactate dehydrogenase inhibition by oxamate in hyperglycemic proximal tubular cells. / Wang, Zhimin; Nielsen, Per Mose; Laustsen, Christoffer; Bertelsen, Lotte Bonde.

    In: Experimental Cell Research, Vol. 378, No. 1, 2019, p. 51-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2018
  5. Published

    Hyperpolarized [1-13 C] pyruvate as a possible diagnostic tool in liver disease. / Kjaergaard, Uffe; Laustsen, Christoffer; Nørlinger, Thomas; Tougaard, Rasmus S; Mikkelsen, Emmeli; Qi, Haiyun; Bertelsen, Lotte B; Jessen, Niels; Stødkilde-Jørgensen, Hans.

    In: Physiological Reports, Vol. 6, No. 23, 12.2018, p. e13943.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Renal Energy Metabolism Following Acute Dichloroacetate and 2,4-Dinitrophenol Administration : Assessing the Cumulative Action with Hyperpolarized [1-13C]Pyruvate MRI. / Bertelsen, Lotte Bonde; Nielsen, Per Mose; Qi, Haiyun; Mariager, Christian Østergaard; Lindhardt, Jakob; Laustsen, Christoffer.

    In: Tomography - A Journal for Imaging Research, Vol. 4, No. 3, 09.2018, p. 105-109.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Acute renal metabolic effect of metformin assessed with hyperpolarised MRI in rats. / Qi, Haiyun; Nielsen, Per M; Schroeder, Marie; Bertelsen, Lotte B; Palm, Fredrik; Laustsen, Christoffer.

    In: Diabetologia, Vol. 61, No. 2, 2018, p. 445-454.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2017
  9. Published

    Can hyperpolarized 13C-Urea be used to assess glomerular filtration rate? a retrospective study. / Østergaard Mariager, Christian; Nielsen, Per Mose; Qi, Haiyun; Schroeder, Marie; Bertelsen, Lotte Bonde; Laustsen, Christoffer.

    In: Tomography - A Journal for Imaging Research, Vol. 3, No. 3, 09.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Hyperpolarized C Magnetic Resonance Imaging Can Detect Metabolic Changes Characteristic of Penumbra in Ischemic Stroke. / Xu, Yafang; Ringgaard, Steffen; Mariager, Christian Østergaard; Bertelsen, Lotte Bonde; Schroeder, Marie; Qi, Haiyun; Laustsen, Christoffer; Stødkilde-Jørgensen, Hans.

    In: Tomography - A Journal for Imaging Research, Vol. 3, No. 2, 06.2017, p. 67-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Acute renal metabolic effect of metformin treatment assessed with hyperpolarized magnetic resonance imaging. / Qi, Haiyun; Nielsen, Per Mose; Schroeder, Marie; Bertelsen, Lotte Bonde; Palm, Fredrik; Laustsen, Christoffer.

    ISMRM 2017 Proceedings. 2017.

    Research output: Contribution to book/anthology/report/proceedingConference abstract in proceedingsResearchpeer-review

  12. Published
  13. Published

    Fumarase activity : an in vivo and in vitro biomarker for acute kidney injury. / Nielsen, Per Mose; Eldirdiri, Abubakr; Bertelsen, Lotte Bonde; Jørgensen, Hans Stødkilde; Ardenkjaer-Larsen, Jan Henrik; Laustsen, Christoffer.

    In: Scientific Reports, Vol. 7, 17.01.2017, p. 40812.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Antioxidant treatment attenuates lactate production in diabetic nephropathy. / Laustsen, Christoffer; Nielsen, Per Mose; Nørlinger, Thomas Stokholm; Qi, Haiyun; Pedersen, Uffe Kjærgaard; Bertelsen, Lotte Bonde; Østergaard, Jakob Appel; Flyvbjerg, Allan; Ardenkjær-Larsen, Jan Henrik; Palm, Fredrik; Stødkilde-Jørgensen, Hans.

    In: American Journal of Physiology: Renal Physiology, Vol. 312, No. 1, 01.01.2017, p. F192-F199.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published
  16. Published
  17. Published

    The potential of hyperpolarized (13)C magnetic resonance spectroscopy to monitor the effect of combretastatin based vascular disrupting agents. / Iversen, Ane B; Busk, Morten; Bertelsen, Lotte B; Laustsen, Christoffer; Munk, Ole L; Nielsen, Thomas; Wittenborn, Thomas R; Bussink, Johan; Lok, Jasper; Stødkilde-Jørgensen, Hans; Horsman, Michael R.

    In: Acta oncologica (Stockholm, Sweden), Vol. 56, 2017, p. 1-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2016
  19. Published

    Renal ischemia and reperfusion assessment with three-dimensional hyperpolarized (13) C,(15) N2-urea. / Nielsen, Per Mose; Szocska Hansen, Esben Søvsø; Nørlinger, Thomas Stokholm; Nørregaard, Rikke; Bonde Bertelsen, Lotte; Stødkilde Jørgensen, Hans; Laustsen, Christoffer.

    In: Magnetic Resonance in Medicine, Vol. 76, No. 5, 11.2016, p. 1524-1530.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Establishment and characterization of porcine focal cerebral ischemic model induced by endothelin-1. / Zhang, Rui; Bertelsen, Lotte Bonde; Flø, Christian; Wang, Yan; Stødkilde-Jørgensen, Hans.

    In: Neuroscience Letters, Vol. 635, 20.10.2016, p. 1-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    (13)C dynamic nuclear polarization for measuring metabolic flux in endothelial progenitor cells. / Nielsen, Nathalie; Laustsen, Christoffer; Bertelsen, Lotte Bonde.

    In: Experimental Cell Research, 05.10.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    In situ lactate dehydrogenase activity - a novel renal cortical imaging biomarker of tubular injury? / Nielsen, Per Mose; Laustsen, Christoffer; Bertelsen, Lotte Bonde; Qi, Haiyun; Mikkelsen, Emmeli; Kristensen, Marie Louise Vindvad; Nørregaard, Rikke; Stødkilde-Jørgensen, Hans.

    In: American Journal of Physiology: Renal Physiology, 21.09.2016, p. ajprenal.00561.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Ex vivo hyperpolarized MR spectroscopy on isolated renal tubular cells: A novel technique for cell energy phenotyping. / Juul, Troels; Palm, Fredrik; Nielsen, Per Mose; Bertelsen, Lotte Bonde; Laustsen, Christoffer.

    In: Magnetic Resonance in Medicine, 16.08.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Diabetes induced renal urea transport alterations assessed with 3D hyperpolarized (13) C,(15) N-Urea. / Bertelsen, Lotte B; Nielsen, Per M; Qi, Haiyun; Nørlinger, Thomas S; Zhang, Xiaolu; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    In: Magnetic Resonance in Medicine, 12.05.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    13C Dynamic Nuclear Polarization NMR for Quantifcation of Metabolic Flux of Endothelial Progenitor Cells. / Nielsen, Nathalie; Laustsen, Christoffer; Stødkilde-Jørgensen, Hans; Bertelsen, Lotte Bonde.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  26. Published

    Characterisation of Adipose Tissue-Derived Mesenchymal Stem Cell Using Hyperpolarized MRS. / Bohn, Anja Bille; Nielsen, Nathalie; Laustsen, Christoffer; Stødkilde-Jørgensen, Hans; Bertelsen, Lotte Bonde.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  27. Published

    Early Diabetic Kidney Maintains the Cortico- Medullary Urea and Sodium Gradient. / Qi, Haiyun; Nørlinger, Thomas; Nielsen, Per Mose; Bertelsen, Lotte Bonde; Xu, Yafang; Palm, Fredrik; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  28. Published

    Hyperpolarized 1-13C Pyruvate Imaging of Porcine Cardiac Metabolism shift by GIK Intervention. / Søvsø Szocska Hansen, Esben; Tougaard, Rasmus Stilling; Mikkelsen, Emmeli; Nørlinger, Thomas; Bertelsen, Lotte Bonde; Ringgaard, Steffen; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  29. Published

    Renal ischemia and reperfusion assessment with 3D hyperpolarized 13C urea. / Nielsen, Per Mose; Søvsø Szocska Hansen, Esben; Nørlinger, Thomas; Nørregaard, Rikke; Bertelsen, Lotte Bonde; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition: International Society for Magnetic Resonance in Medicine, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  30. Published

    In Situ lactate dehydrogenase activiy-a novel renal cortical imaging biomarker of tubular injury? / Nielsen, Per Mose; Laustsen, Christoffer; Bertelsen, Lotte Bonde; Qi, Haiyun; Mikkelsen, Emmeli; Kristensen, Marie-Louise vinvad; Nørregaard, Rikke; Stødkilde-Jørgensen, Hans.

    2016. Poster session presented at Experimental biology 2016, San Diego, United States.

    Research output: Contribution to conferencePosterResearch

  31. Published

    Early diabetic kidney maintains the corticomedullary urea and sodium gradient. / Qi, Haiyun; Nørlinger, Thomas S; Nielsen, Per M; Bertelsen, Lotte B; Mikkelsen, Emmeli; Xu, Yafang; Stødkilde Jørgensen, Hans; Laustsen, Christoffer.

    In: Physiological Reports, Vol. 4, No. 5, 03.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Diabetes induced renal urea transport alterations assessed with 3D hyperpolarized 13C,15N-urea. / Bertelsen, Lotte Bonde; Nielsen, Per Mose; Qi, Haiyun; Nørlinger, Thomas; Zhang, Xiaolu; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    In: Magnetic Resonance in Medicine, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Lactate dehydrogenase activity, a novel renal cortical imaging bio-marker of cortical injury. / Nielsen, Per Mose; Laustsen, Christoffer; Bertelsen, Lotte Bonde; Qi, Haiyun; Mikkelsen, Emmeli; Kristensen, Marie-Louise vinvad; Nørregaard, Rikke; Stødkilde-Jørgensen, Hans.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  34. Published

    Renal Ischemia/Reperfusion necrosis monitoring with hyperpolarized fumarate. / Nielsen, Per Mose; Eldirdiri, Abubakr; Bertelsen, Lotte Bonde; Qi, Haiyun; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    2016. Abstract from ISMRM 2016 Annual Meeting & Exhibition: International Society for Magnetic Resonance in Medicine, Singapore, Singapore.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  35. Published

    Renal Urea Transport Alterations with Prolonged Hyperglycaemia. / Bertelsen, Lotte Bonde; Nielsen, Per Mose; Qi, Haiyun; Nørlinger, Thomas; Zhang, Xiaolu; Stødkilde-Jørgensen, Hans; Laustsen, Christoffer.

    2016. Poster session presented at Experimental biology 2016, San Diego, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. 2015
  37. Published

    Hyperpolarized (13) C urea relaxation mechanism reveals renal changes in diabetic nephropathy. / Laustsen, Christoffer; Nørlinger, Thomas; Christoffer Hansen, David; Qi, Haiyun; Mose Nielsen, Per; Bonde Bertelsen, Lotte; Henrik Ardenkjaer-Larsen, Jan; Stødkilde Jørgensen, Hans.

    In: Magnetic Resonance in Medicine, Vol. 75, No. 2, 19.11.2015, p. 515-518.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Acute porcine renal metabolic effect of endogastric soft drink administration assessed with hyperpolarized [1-13c]pyruvate. / Laustsen, Christoffer; Søvsø Szocska Hansen, Esben; Pedersen, Uffe; Bertelsen, Lotte Bonde; Ringgaard, Steffen; Stødkilde-Jørgensen, Hans.

    In: Magnetic Resonance in Medicine, Vol. 74/2, 01.08.2015, p. 558-563.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Bioreactor for quantification of cell metabolism by MR-hyperpolarization. / Lauritsen, Simon Holm; Bertelsen, Lotte Bonde; Daugård, Preben; Laustsen, Christoffer; Nielsen, Nathalie; Nygaard, Jens Vinge; Stødkilde-Jørgensen, Hans.

    In: Biomedical Physics & Engineering Express, Vol. 1, No. 4, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Low cell number perfusion bioreactor system for hyperpolarized MRS in a MRI setting. / Bertelsen, Lotte Bonde; Lauritsen, Simon Holm; Laustsen, Christoffer; Christensen, Preben Daugård; Zhang, Xiaolu; Stødkilde-Jørgensen, Hans.

    2015. Abstract from ISMRM 2015 23rd Annual Meeting, Toronto, Canada.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  41. Published

    Principle and application of hyperpolarized magnetic resonance spectroscopy. / Qi, Haiyun; Zhang, Xiaolu; Xu, Yafang; Wen, Jianguo; Xu, Yuming; Cheng, Jianliang; Chen, Albert P.; Bertelsen, Lotte Bonde; Ringgaard, Steffen; Laustsen, Christoffer; Stødkilde-Jørgensen, Hans.

    In: Chinese Journal of Magnetic Resonance Imaging , 2015, p. 881-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 2014
  43. Published

    Are endothelial outgrowth cells a potential source for future re-vascularization therapy? / Bertelsen, Lotte B; Bohn, Anja B; Smith, Màiri; Mølgaard, Brian; Møller, Bjarne; Stødkilde-Jørgensen, Hans; Kristensen, Peter.

    In: Experimental Gerontology, Vol. 58, 01.10.2014, p. 132-138.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    In vivo bio-distribution and homing of endothelial outgrowth cells in a tumour model. / Bertelsen, Lotte B; Hagensen, Mette; Busk, Morten; Zhang, Rui; Knudsen, Anne S; Nielsen, Nathalie; Falborg, Lise; Møller, Bjarne K; Horsman, Michael R; Stødkilde-Jørgensen, Hans.

    In: Nuclear Medicine and Biology, 01.08.2014, p. 848-855.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    A combretastatin-mediated decrease in neutrophil concentration in peripheral blood and the impact on the anti-tumor activity of this drug in two different murine tumor models. / Bohn, Anja Bille; Wittenborn, Thomas; Brems-Eskildsen, Anne Sofie; Laurberg, Tinne; Bertelsen, Lotte Bonde; Nielsen, Thomas; Stødkilde-Jørgensen, Hans; Møller, Bjarne Kuno; Horsman, Michael R.

    In: PLOS ONE, Vol. 9, No. 10, 2014, p. e110091.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Tracing vasculogenesis in tumours with special emphasis on characterisation and involvement of endothelial outgrowth cells : PhD dissertation. / Bonde Bertelsen, Lotte.

    [Aarhus] : Master of Public health, Aarhus Universitet, 2014. 160 p.

    Research output: Book/anthology/dissertation/reportPh.D. thesisResearch

  47. Published

    Treatment with a vascular disrupting agent does not increase recruitment of indium labelled human endothelial outgrowth cells in an experimental tumour model. / Bertelsen, Lotte B; Bohn, Anja B; Shen, Yuan Yuan; Falborg, Lise; Stødkilde-Jørgensen, Hans; Horsman, Michael R.

    In: B M C Cancer, Vol. 14, 2014, p. 903.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. 2012
  49. Published

    Treatment with the vascular disrupting agent Combretastatin is associated with impaired AQP2 trafficking and increased urine output. / Bohn, Anja Bille; Norregaard, Rikke; Stødkilde-Jørgensen, Lene; Wang, Yan; Bertelsen, Lotte B; Fenton, Robert A; Matchkov, Vladimir V; Bouzinova, Elena V; Horsman, Michael R; Frokiaer, Jorgen; Stødkilde-Jørgensen, Hans.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 2012, p. R186-R198.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. 2011
  51. Published

    Vascular effects of plinabulin (NPI-2358) and the influence on tumour response when given alone or combined with radiation. / Bertelsen, Lotte B; Shen, Yuan Yuan; Nielsen, Thomas; Stødkilde-Jørgensen, Hans; Lloyd, G Kenneth; Siemann, Dietmar W; Horsman, Michael R.

    In: International Journal of Radiation Biology, Vol. 87, No. 11, 11.2011, p. 1126-1134.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. 2010
  53. Published

    Human Herpesvirus 6B Induces Phenotypic Maturation Without IL-10 and IL-12p70 Production in Dendritic Cells. / Bertelsen, Lotte Bonde; Petersen, Charlotte Christie; Kofod-Olsen, E; Øster, Bodil; Höllsberg, P; Agger, R; Hokland, M.

    In: Scandinavian Journal of Immunology, Vol. 71, No. 6, 2010, p. 431-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Magnetisk resonans : et nyt forskningsinstrument. / Bonde Bertelsen, Lotte; Lauridsen, Henrik; Thrysøe, Samuel; Stødkilde-Jørgensen, Hans.

    In: Medicinsk Teknologi & Informatik, Vol. 7, No. 4, 2010, p. 14-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  55. Published

    NPI-2358 Rapidly Inhibit the Blood Flow in Tumour Treatment by Analyzing Dynamic Contrast Enhanced Magnetic Resonance Imaging Parameters. / Shen, Yuan Yuan; Liu, Cheng-Xia; Bertelsen, Lotte Bonde; Nielsen, Thomas; Horsman, Michael Robert; Stødkilde-Jørgensen, Hans.

    In: China Journal of Cancer Prevention and Treatment, Vol. 7, 2010, p. 488-490.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  56. Published

    Time and dose dependent vascular effects of NPI-2358 in mouse tumour models. / Bertelsen, Lotte Bonde; Shen, Yuan Yuan; Bohn, Anja Bille; Nielsen, Thomas; Loyd, GK; Stødkilde-Jørgensen, Hans; Siemann, DW; Horsman, Michael Robert.

    2010. Poster session presented at   Time and dose dependent vascular effects of NPI-2358 in mouse tumour models, .

    Research output: Contribution to conferencePosterResearch

  57. 2009
  58. Published

    Vascular changes induced by the novel vascular disrupting drug NPI-2358 in a murine tumour model monitored with DCE-MRI. / Bertelsen, Lotte Bonde; Shen, Yuan Yuan; Nielsen, Thomas; Lloyd, GK; Stødkilde-Jørgensen, Hans; Horsman, Michael Robert.

    2009. Abstract from Dansk selskab for cancerforsknings årsmøde, Vilvorde, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  59. 2008
  60. Published

    Visualization of endothelial progenitor cells in tumours by inverted MRI signals. / Bertelsen, Lotte Bonde; Ringgaard, Steffen; Horsman, Michael Robert; Stødkilde-Jørgensen, Hans.

    2008. Poster session presented at World Molecular Imaging Congress i Nice i september 2008, Nice, France.

    Research output: Contribution to conferencePosterResearchpeer-review