Lise Torp Jensen

Research output

Research output per year 1995 1995 1996 1997 1998 2006 2008 2009 2011 2020 2022 2024 2024

• 31 Journal article
• 3 Review
• 2 Conference abstract in proceedings
• 1 Comment/debate/letter to the editor

Research output per year

Research output per year

Search results

• 2024

  A repair pathway lost in multiple sclerosis provides a new drug opportunity

  Jensen, L. T., Attfield, K. E. & Fugger, L., Mar 2024, In: Nature Immunology. 25, 3, p. 385-386 2 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  • Multiple Sclerosis 100%
  • New Drugs 100%
  • Repair Pathway 100%
  • Protective Factors 50%
  • HB-EGF 50%
  1 Citation (Scopus)

• Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

  Barrie, W., Yang, Y., Irving-Pease, E. K., Attfield, K. E., Scorrano, G., Jensen, L. T., Armen, A. P., Dimopoulos, E. A., Stern, A., Refoyo-Martinez, A., Pearson, A., Ramsøe, A., Gaunitz, C., Demeter, F., Jørkov, M. L. S., Møller, S. B., Springborg, B., Klassen, L., Hyldgård, I. M. & Wickmann, N. & 11 others, Vinner, L., Korneliussen, T. S., Allentoft, M. E., Sikora, M., Kristiansen, K., Rodriguez, S., Nielsen, R., Iversen, A. K. N., Lawson, D. J., Fugger, L. & Willerslev, E., Jan 2024, In: Nature. 625, p. 321-328 8 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  Open Access

  • Genetic Risk 100%
  • Multiple Sclerosis 100%
  • Immune Response 16%
  • Immune-Related Gene 16%
  • Immunogenetics 16%
  49 Citations (Scopus)
• 2023

  Allosteric TYK2 inhibition: redefining autoimmune disease therapy beyond JAK1-3 inhibitors

  Jensen, L. T., Attfield, K. E., Feldmann, M. & Fugger, L., Nov 2023, In: EBioMedicine. 97, 104840.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  Open Access

  • Cytokine 100%
  • Janus Kinase Inhibitor 100%
  • Genetics 50%
  • Clinical Trial 50%
  • Enzyme Active Site 50%
  26 Citations (Scopus)
• 2022

  Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice

  Viskaitis, P., Arnold, M., Garau, C., Jensen, L. T., Fugger, L., Peleg-Raibstein, D. & Burdakov, D., Apr 2022, In: Current biology : CB. 32, 8, p. 1812-1821.e4 10 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Orexin 100%
  • Nonessential Amino Acid 100%
  • Behavior (Neuroscience) 10%
  • Cholecystokinin 5%
  • Essential Amino Acid 5%
  21 Citations (Scopus)

• Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade

  Kaur, G., Porter, C. B. M., Ashenberg, O., Lee, J., Riesenfeld, S. J., Hofree, M., Aggelakopoulou, M., Subramanian, A., Kuttikkatte, S. B., Attfield, K. E., Desel, C. A. E., Davies, J. L., Evans, H. G., Avraham-Davidi, I., Nguyen, L. T., Dionne, D. A., Neumann, A. E., Jensen, L. T., Barber, T. R. & Soilleux, E. & 5 others, Carrington, M., McVean, G., Rozenblatt-Rosen, O., Regev, A. & Fugger, L., 2022, In: Nature Communications. 13, 1, 25 p., 4398.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  Open Access

  • KIR2DL1 100%
  • Cascade Effect 50%
  12 Citations (Scopus)

• The immunology of multiple sclerosis

  Attfield, K. E., Jensen, L. T., Kaufmann, M., Friese, M. A. & Fugger, L., Dec 2022, In: Nature Reviews. Immunology. 22, 12, p. 734-750 17 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  • Immunology 100%
  • Immunocompetent Cell 100%
  • Multiple Sclerosis 100%
  • Central Nervous System 25%
  • Cell Population 25%
  198 Citations (Scopus)
• 2020

  A novel neurodegenerative spectrum disorder in patients with MLKL deficiency

  Faergeman, S. L., Evans, H., Attfield, K. E., Desel, C., Kuttikkatte, S. B., Sommerlund, M., Jensen, L. T., Frokiaer, J., Friese, M. A., Matthews, P. M., Luchtenborg, C., Brügger, B., Oturai, A. B., Dendrou, C. A. & Fugger, L., May 2020, In: Cell Death and Disease. 11, 303.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  Open Access

  • Spectrum Disorder 100%
  • Necroptosis 100%
  • Mixed Lineage Kinase 100%
  • Kinase 100%
  • Phosphotransferase 100%
  20 Citations (Scopus)

• Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

  Fugger, L., Jensen, L. T. & Rossjohn, J., Apr 2020, In: Cell. 181, 1, p. 63-80 18 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  • Autoimmune Disease 100%
  • Motivation 100%
  • Host 100%
  • Diseases 50%
  • Side Effect 50%
  253 Citations (Scopus)

• Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions

  Dagkonaki, A., Avloniti, M., Evangelidou, M., Papazian, I., Kanistras, I., Tseveleki, V., Lampros, F., Tselios, T., Jensen, L. T., Möbius, W., Ruhwedel, T., Androutsou, M. E., Matsoukas, J., Anagnostouli, M., Lassmann, H. & Probert, L., Nov 2020, In: Frontiers in Immunology. 11, 575451.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  Open Access

  • Allergic Encephalomyelitis 100%
  • Clonal Anergy 40%
  • T-Cell Tolerance 40%
  17 Citations (Scopus)
• 2017

  Structural and regulatory diversity shape HLA-C protein expression levels

  Kaur, G., Gras, S., Mobbs, J. I., Vivian, J. P., Cortes, A., Barber, T., Kuttikkatte, S. B., Jensen, L. T., Attfield, K. E., Dendrou, C. A., Carrington, M., McVean, G., Purcell, A. W., Rossjohn, J. & Fugger, L., 26 Jun 2017, In: Nature Communications. 8, p. 15924 15924.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Infectious Disease 100%
  • Peptide-Binding Cleft 100%
  • Cell Surface 100%
  • Immune Response 100%
  • Phylogeny 100%
  82 Citations (Scopus)
• 2016

  Inhibitory Interplay between Orexin Neurons and Eating

  González, J. A., Jensen, L. T., Iordanidou, P., Strom, M., Fugger, L. & Burdakov, D., 26 Sept 2016, In: Current Biology. 26, 18, p. 2486-91 6 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Feeding Behavior 100%
  • Orexin 100%
  • Energy Intake 50%
  • Cell Activity 5%
  • Behavior (Neuroscience) 2%
  103 Citations (Scopus)
• 2012

  Convergent inputs from electrically and topographically distinct orexin cells to locus coeruleus and ventral tegmental area

  González, J. A., Jensen, L. T., Fugger, L. & Burdakov, D., 2012, In: The European journal of neuroscience. 35, 9, p. 1426-32 7 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Zona Incerta 100%
  49 Citations (Scopus)
• 2011

  Activation of central orexin/hypocretin neurons by dietary amino acids

  Karnani, M. M., Apergis-Schoute, J., Adamantidis, A., Jensen, L. T., de Lecea, L., Fugger, L. & Burdakov, D., 2011, In: Sensory Neuron. 72, 4, p. 616-29 14 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Amino Acids 100%
  • Orexin 100%
  • Brain Slice 100%
  • Macronutrient 42%
  • Essential Amino Acid 14%
  135 Citations (Scopus)

• Direct and indirect control of orexin/hypocretin neurons by glycine receptors

  Karnani, M. M., Venner, A., Jensen, L. T., Fugger, L. & Burdakov, D., 1 Feb 2011, In: Journal of Physiology. 589, 3, p. 639-651

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Glycine Receptor 100%
  • Strychnine 7%
  • Perforated Patch Clamp 3%
  • Gramicidin 3%
  • Glycine Receptor Antagonist 3%
  28 Citations (Scopus)

• Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels

  Venner, A., Karnani, M. M., Gonzalez, J. A., Jensen, L. T., Fugger, L. & Burdakov, D., 2011, In: Journal of Physiology. 589, Pt 23, p. 5701-8 8 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Orexin 100%
  • Oligomycin 30%
  • Metabolic Pathway 30%
  • Adenosine Triphosphate 10%
  • Feeding Behavior 10%
  59 Citations (Scopus)

• Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells

  Du Pré, M. F., Kozijn, A. E., van Berkel, L. A., ter Borg, M. N. D., Lindenbergh-Kortleve, D., Jensen, L. T., Kooy-Winkelaar, Y., Koning, F., Boon, L., Nieuwenhuis, E. E. S., Sollid, L. M., Fugger, L. & Samsom, J. N., 1 Aug 2011, In: Gastroenterology. 141, 2, p. 610-620.e2

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Regulatory T Cell 100%
  • Mouse 100%
  • Coeliac Disease 100%
  56 Citations (Scopus)
• 2009

  Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons

  González, J. A., Jensen, L. T., Doyle, S. E., Miranda-Anaya, M., Menaker, M., Fugger, L., Bayliss, D. A. & Burdakov, D., 2009, In: European Journal of Neuroscience. 30, 1, p. 57-64 7 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Orexin 100%
  • Excitability 100%
  • Patch Clamp Technique 11%
  • Green Fluorescent Protein 11%
  • Brain Slice 11%
  56 Citations (Scopus)

• T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides

  Harkiolaki, M., Holmes, S. L., Svendsen, P., Gregersen, J. W., Jensen, L. T., McMahon, R., Friese, M. A., van Boxel, G., Etzensperger, R., Tzartos, J. S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E. D., Palace, J., Esiri, M. M., van der Merwe, P. A., Jones, E. Y. & Fugger, L., 2009, In: Immunity. 30, 3, p. 348-57 9 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • T Cell Receptor 100%
  • T Cell 100%
  • T Cell-Mediated Autoimmune Disease 100%
  • Autoantigen 33%
  • Receptor Binding 33%
  145 Citations (Scopus)
• 2008

  Adaptive sugar sensors in hypothalamic feeding circuits.

  Williams, R. H., Alexopoulos, H., Jensen, L. T., Fugger, L. & Burdakov, D., 2008, In: Proceedings of the National Academy of Sciences (PNAS). 105, 33, p. 11975-80 5 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Feeding Behavior 100%
  • Orexin 100%
  • Wakefulness 33%
  • Energy Balance 33%
  103 Citations (Scopus)

• Metabolism-independent sugar sensing in central orexin neurons.

  González, J. A., Jensen, L. T., Fugger, L. & Burdakov, D., 2008, In: Diabetes. 57, 10, p. 2569-76 7 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Glucosamine 100%
  • Glucokinase 49%
  • Patch Clamp Technique 49%
  • Alpha Methylglucoside 49%
  • Alloxan 49%
  104 Citations (Scopus)

• Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

  Friese, M. A., Jakobsen, K. B., Friis, L., Etzensperger, R., Craner, M. J., McMahon, R. M., Jensen, L. T., Huygelen, V., Jones, E. Y., Bell, J. I. & Fugger, L., 2008, In: Nature Medicine. 14, 11, p. 1227-35 8 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Cytotoxic T-Cell 100%
  • Multiple Sclerosis 100%
  • Major Histocompatibility Complex 75%
  • HLA-A 37%
  • T-Helper Cell 25%
  161 Citations (Scopus)
• 2007

  Control of hypothalamic orexin neurons by acid and CO2

  Williams, R. H., Jensen, L. T., Verkhratsky, A., Fugger, L. & Burdakov, D., 19 Jun 2007, In: Proceedings of the National Academy of Sciences (PNAS). 104, 25, p. 10685-90 6 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Orexin 100%
  • Wakefulness 18%
  • Firing Rate 18%
  • Behavior (Neuroscience) 9%
  • Narcolepsy 9%
  264 Citations (Scopus)
• 2006

  A role for tandem-pore K+ channels in hypothalamic sensing of glucose.

  Burdakov, D., Jensen, L. T., Alexopoulos, H., Gerasimenko, O., Fugger, L. H. & Verkhratsky, A., 2006, In: Neuron. 50, p. 711-722

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  259 Citations (Scopus)

• Humanized mouse models for organ-specific autoimmune diseases.

  Friese, M. A., Jensen, L. T. & Fugger, L. H., 2006, In: Curr Opinion Immunol. 18, 6, p. 704-9

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  24 Citations (Scopus)

• Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose

  Burdakov, D., Jensen, L. T., Alexopoulos, H., Williams, R. H., Fearon, I. M., O'Kelly, I., Gerasimenko, O., Fugger, L. & Verkhratsky, A., 1 Jun 2006, In: Neuron. 50, 5, p. 711-22 12 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Orexin 100%
  • Potassium Channel 100%
  • Metabolic Pathway 50%
  • Behavior (Neuroscience) 25%
  • Adenosine Triphosphate 25%
• 2003

  Inherited deficiency of mannan-binding lectin-associated serine protease 2

  Stengaard-Pedersen, K., Thiel, S., Gadjeva, M., Møller-Kristensen, M., Sørensen, R., Jensen, L. T., Sjøholm, A. G., Fugger, L. & Jensenius, J. C., 2003, In: The New England Journal of Medicine. 349, 6, p. 554-60 7 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
• 1998

  A mosaic gene structure is displayed by the vaa gene of Mycoplasma hominis

  Boesen, T., Emmersen, J. M. G., Jensen, L. T., Ladefoged, S., Thorsen, P., Birkelund, S. & Christiansen, G., 1998, IOM Lett. Vol. 5. 1 p.

  Research output: Contribution to book/anthology/report/proceeding › Conference abstract in proceedings › Research

• Antigenic and genomic homogeneity of successive Mycoplasma hominis isolates.

  Jensen, L. T., Thorsen, P., Møller, B., Birkelund, S. & Christiansen, G., 1998, In: Journal of Medical Microbiology. 47, 8, p. 659-66 7 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20 Citations (Scopus)

• Mycoplasma contamination of Chlamydia pneumoniae isolates

  Huniche, B., Jensen, L. T., Birkelund, S. & Christiansen, G., 1998, In: Scandinavian Journal of Infectious Diseases. 30, p. 181-7

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Mycoplasma orale 100%
  15 Citations (Scopus)

• The Mycoplasma hominis vaa gene displays a mosaic gene structure

  Boesen, T., Emmersen, J., Jensen, L. T., Ladefoged, S. A., Thorsen, P., Birkelund, S. & Christiansen, G., Jul 1998, In: Molecular Microbiology. 29, 1, p. 97-110 14 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Gene Structure 100%
  • Mosaicism 100%
  • Mycoplasma hominis 100%
  • Nested Gene 50%
  • N-Terminus 50%
  19 Citations (Scopus)
• 1997

  Antigenic variation of Mycoplasma hominis and its role in bacterial vaginosis

  Christiansen, G., Jensen, L. T., Boesen, T., Emmersen, J. M. G., Ladefoged, S. & Birkelund, S., 1997, In: Japanese Journal of Mycoplasmology. 29, p. 16 1 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

• Molecular biology of Mycoplasma

  Christiansen, G., Jensen, L. T., Boesen, T., Emmersen, J. M. G., Ladefoged, S., Schiøtz, L.-K. & Birkelund, S., 1997, In: Wien Klin Wochenschr. 109, 14-15, p. 557-561 5 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Mycoplasma 100%
  • Antigenic Variation 50%
  • Mycoplasma hominis 25%
  • Mycoplasma genitalium 25%
  • Mycoplasma pneumoniae 25%
  12 Citations (Scopus)
• 1996

  Analysis by PCR of various forms of the Mycoplasma hominis gene encoding a variable surface exposed membrane protein, P50, associated with adhesion

  Christiansen, G., Emmersen, J. M. G., Boesen, T., Jensen, L. T., Ladefoged, S. & Birkelund, S., 1996, IOM Lett. Vol. 4. p. 374- 375 2 p.

  Research output: Contribution to book/anthology/report/proceeding › Conference abstract in proceedings › Research

• Analysis of 0.5-kilobase-pair repeats in the Mycoplasma hominis lmp gene system and identification of gene products

  Ladefoged, S., Jensen, L. T., Brock, B., Birkelund, S. & Christiansen, G., May 1996, In: Journal of Bacteriology. 178, 10, p. 2775-84 10 p.

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Gene Product 100%
  • Mycoplasma hominis 100%
  • Surface Property 50%
  • Stop Codon 50%
  • Polymerase Chain Reaction 50%
  22 Citations (Scopus)

• Analysis of 0.5-kilobase-pair repeats in the Mycoplasma hominis lmp gene system and identification of gene products.

  Ladefoged, S., Jensen, L. T., Brock, B., Birkelund, S. & Christiansen, G., 1996, In: J Bacteriol. 178, p. 2775-84

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Gene Sequence 100%
  22 Citations (Scopus)
• 1995

  A 135-kilodalton surface antigen of Mycoplasma hominis PG21 contains multiple directly repeated sequences.

  Ladefoged, S., Birkelund, S., Hauge, S., B., B., Jensen, L. T. & Christiansen, G., 1995, In: Infect Immun. 63, p. 212-23

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Nucleic Acid Base Substitution 100%
  27 Citations (Scopus)

• Selection of Mycoplasma hominis PG21 deletion mutants by cultivation in the presence of monoclonal antibody 552.

  Jensen, L. T., Ladefoged, S., Birkelund, S. & Christiansen, G., 1995, In: Infect Immun. 63, p. 336-47

  Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  • Deletion Mutant 100%
  • Monoclonal Antibody 100%
  • Mycoplasma hominis 100%
  • Surface Property 25%
  • Subcloning 25%
  23 Citations (Scopus)