Erratum to : Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations (Scientific Reports, (2017), 7, 1, (6774), 10.1038/s41598-017-07057-3). / Nielsen, Helene Myrtue; Andersen, Christen Lykkegaard; Westman, Maj; Kristensen, Lasse Sommer; Asmar, Fazila; Kruse, Torben Arvid; Thomassen, Mads; Larsen, Thomas Stauffer; Skov, Vibe; Hansen, Lise Lotte; Bjerrum, Ole Weis; Hasselbalch, Hans Carl; Punj, Vasu; Grønbæk, Kirsten.
In: Scientific Reports, Vol. 8, No. 1, 17311, 01.12.2018.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate › Research › peer-review
Chronic lymphocytic leukemia patients with heterogeneously or fully methylated LPL promotor display longer time to treatment. / Daugaard, Iben; Hussmann, Dianna; Kristensen, Louise; Kristensen, Thomas; Kjeldsen, Tina E; Nyvold, Charlotte G; Larsen, Thomas S; Møller, Michael B; Hansen, Lise Lotte; Wojdacz, Tomasz K.
In: Epigenomics, Vol. 10, No. 9, 09.2018, p. 1155-1166.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The polymorphic insertion of the luteinizing hormone receptor "insLQ" show a negative association to LHR gene expression and to the follicular fluid hormonal profile in human small antral follicles. / Borgbo, T; Chrudimska, J; Macek, M; Jeppesen, J V; Bøtkjær, Jane Alrø; Kristensen, S G; Macklon, K T; Ernst, E; Hansen, L L; Yding Andersen, C.
In: Molecular and Cellular Endocrinology, Vol. 460, 15.01.2018, p. 57-62.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
miRNA profiling identifies deregulated miRNAs associated with osteosarcoma development and time to metastasis in two large cohorts. / Andersen, Gitte Brinch; Knudsen, Alice; Hager, Henrik; Hansen, Lise Lotte; Tost, Jörg.
In: Molecular Oncology, 02.01.2018.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Methylation-Sensitive High Resolution Melting (MS-HRM). / Hussmann, Dianna; Hansen, Lise Lotte.
In: Methods in molecular biology (Clifton, N.J.), Vol. 1708, 2018, p. 551-571.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research
miR-151a induces partial EMT by regulating E-cadherin in NSCLC cells. / Daugaard, Iben; Sanders, K J; Idica, A; Vittayarukskul, K; Hamdorf, M; Krog, J D; Chow, R; Jury, D; Hansen, L L; Hager, H; Lamy, P; Choi, C L; Agalliu, D; Zisoulis, D G.
In: Oncogenesis, Vol. 6, No. 7, 31.07.2017, p. e366.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Epigenetic changes in myelofibrosis : Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations. / Nielsen, Helene Myrtue; Andersen, Christen Lykkegaard; Westman, Maj; Kristensen, Lasse Sommer; Asmar, Fazila; Kruse, Torben Arvid; Thomassen, Mads; Larsen, Thomas Stauffer; Skov, Vibe; Hansen, Lise Lotte; Bjerrum, Ole Weis; Hasselbalch, Hans Carl; Punj, Vasu; Gronbaek, Kirsten.
In: Scientific Reports, Vol. 7, 6774, 28.07.2017.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The Common Follicle-Stimulating Hormone Receptor (FSHR) Promoter Polymorphism FSHR -29G > A Affects Androgen Production in Normal Human Small Antral Follicles. / Borgbo, Tanni; Klučková, Hana; Macek, Milan; Chrudimska, Jana; Kristensen, Stine Gry; Hansen, Lise Lotte; Andersen, Claus Yding.
In: Frontiers in Endocrinology, Vol. 8, 122, 02.06.2017, p. 122.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The association between miR-34 dysregulation and distant metastases formation in lung adenocarcinoma. / Daugaard, Iben; Knudsen, Alice; Kjeldsen, Tina E; Hager, Henrik; Hansen, Lise Lotte.
In: Experimental and Molecular Pathology, Vol. 102, No. 3, 06.2017, p. 484-491.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma. / Daugaard, Iben; Venø, Morten T.; Yan, Yan; Kjeldsen, Tina E.; Lamy, Philippe; Hager, Henrik; Kjems, Jørgen; Hansen, Lise Lotte.
In: OncoTarget, Vol. 8, No. 16, 2017, p. 27047-27061.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Identification and validation of candidate epigenetic biomarkers in lung adenocarcinoma. / Daugaard, Iben; Dominguez, Diana; Kjeldsen, Tina E; Kristensen, Lasse S; Hager, Henrik; Wojdacz, Tomasz K; Hansen, Lise Lotte.
In: Scientific Reports, Vol. 6, 35807, 26.10.2016.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications. / Bock, Christoph; Halbritter, Florian; Carmona, Francisco J.; Tierling, Sascha; Datlinger, Paul; Assenov, Yassen; Berdasco, María; Bergmann, Anke K.; Booher, Keith; Busato, Florence; Campan, Mihaela; Dahl, Christina; Dahmcke, Christina M.; Diep, Dinh; Fernández, Agustín F.; Gerhauser, Clarissa; Haake, Andrea; Heilmann, Katharina; Holcomb, Thomas; Hussmann, Dianna; Ito, Mitsuteru; Kläver, Ruth; Kreutz, Martin; Kulis, Marta; Lopez, Virginia; Nair, Shalima S.; Paul, Dirk S.; Plongthongkum, Nongluk; Qu, Wenjia; Queirós, Ana C.; Reinicke, Frank; Sauter, Guido; Schlomm, Thorsten; Statham, Aaron; Stirzaker, Clare; Strogantsev, Ruslan; Urdinguio, Rocío G.; Walter, Kimberly; Weichenhan, Dieter; Weisenberger, Daniel J.; Beck, Stephan; Clark, Susan J.; Esteller, Manel; Ferguson-Smith, Anne C.; Fraga, Mario F.; Guldberg, Per; Hansen, Lise Lotte; Laird, Peter W.; Martín-Subero, José I.; Nygren, Anders O H; Peist, Ralf; Plass, Christoph; Shames, David S.; Siebert, Reiner; Sun, Xueguang; Tost, Jörg; Walter, Jörn; Zhang, Kun.
In: Nature Biotechnology, Vol. 34, No. 7, 01.07.2016, p. 726-737.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges. / Thingholm, Louise Bruun; Andersen, Lars; Makalic, Enes; Southey, Melissa C.; Thomassen, Mads; Hansen, Lise Lotte.
In: Frontiers in Genetics, Vol. 7, 01.02.2016, p. 1-13.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors. / Nielsen, Helene Myrtue; How-Kit, Alexandre; Guerin, Carole; Castinetti, Frederic; Vollan, Hans Kristian Moen; De Micco, Catherine; Daunay, Antoine; Taieb, David; Van Loo, Peter; Besse, Celine; Kristensen, Vessela N; Hansen, Lise Lotte; Barlier, Anne; Sebag, Frederic; Tost, Jörg.
In: Endocrine - Related Cancer, Vol. 22, No. 6, 22.12.2015, p. 953-67.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Size matters: Associations between the androgen receptor CAG repeat length and the intrafollicular hormone milieu : Associations between the androgen receptor CAG repeat length and the intrafollicular hormone milieu. / Borgbo, T; Macek, M; Chrudimska, J; Jeppesen, J V; Hansen, L L; Andersen, C Yding.
In: Molecular and Cellular Endocrinology, 25.09.2015, p. 1-6.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The influence of DNA degradation in formalin-fixed, paraffin-embedded (FFPE) tissue on locus-specific methylation assessment by MS-HRM. / Daugaard, Iben Lyster; Kjeldsen, Tina E; Hager, Henrik; Hansen, Lise Lotte; Wojdacz, Tomasz K.
In: Experimental and Molecular Pathology, Vol. 99, No. 3, 2015, p. 632–640.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Effect of the FSH receptor single nucleotide polymorphisms (FSHR 307/680) on the follicular fluid hormone profile and the granulosa cell gene expression in human small antral follicles. / Borgbo, Tanni Kjær; Jeppesen, J V; Lindgren, I; Lundberg Giwercman, Y; Hansen, Lise Lotte; Yding Andersen, C.
In: Molecular Human Reproduction, 17.11.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Heterogeneous and low-level methylation of novel biomarker candidates for breast cancer clinical management. / Wojdacz, Tomasz K.; Windeløv, Johanne Agerlin; Thestrup, Britta Boserup; Damsgaard, Tine Engberg; Overgaard, Jens; Hansen, Lise Lotte.
In: Cancer Research, Vol. 74, No. 19, 10.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Improved reproducibility in genome-wide DNA methylation analysis for PAXgene® fixed samples compared to restored FFPE DNA. / Andersen, Gitte Brinch; Hager, Henrik; Hansen, Lise Lotte; Tost, Jörg.
In: Analytical Biochemistry, Vol. 468C, 29.09.2014, p. 50-58.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Genotyping common FSHR polymorphisms based on competitive amplification of differentially melting amplicons (CADMA). / Borgbo, Tanni; Sommer Kristensen, Lasse; Lindgren, Ida; Yding Andersen, Claus; Hansen, Lise Lotte.
In: Journal of Assisted Reproduction and Genetics, 21.09.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Identification and characterization of locus specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis. / Wojdacz, Tomasz K; Windeløv, Johanne Agerlin; Thestrup, Britta Boserup; Damsgaard, Tine Engberg; Overgaard, Jens; Hansen, Lise Lotte.
In: Breast Cancer Research (Online Edition), Vol. 16, R17, 03.02.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
ELMO3: a direct driver of cancer metastasis? / Kristensen, Lasse Sommer; Søes, Signe; Hansen, Lise Lotte.
In: Cell Cycle, Vol. 13, No. 16, 2014, p. 2483-4.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Hypomethylation and increased expression of the putative oncogene ELMO3 are associated with lung cancer development and metastases formation. / Søes, Signe; Daugaard, Iben Lyster; Sørensen, Brita Singers; Carus, Andreas; Mattheisen, Manuel; Alsner, Jan; Overgaard, Jens; Hager, Henrik; Hansen, Lise Lotte; Kristensen, Lasse Sommer.
In: Oncoscience, Vol. 1, No. 5, 2014, p. 367-74.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A role for immunohistochemical detection of BRAF V600E prior to BRAF-inhibitor treatment of malignant melanoma? / Lade-Keller, Johanne; Kristensen, Lasse Sommer; Riber-Hansen, Rikke; Guldberg, Per; Hansen, Lise Lotte; Steiniche, Torben; Hager, Henrik.
In: Journal of Clinical Pathology, Vol. 66, No. 8, 08.2013, p. 723-5.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary Non-Small Cell Lung Cancers and brain and lymph node metastases. / Søes, Signe; Sørensen, Brita Singers; Alsner, Jan; Overgaard, Jens; Hager, Henrik; Hansen, Lise Lotte; Kristensen, Lasse Sommer.
In: Lung Cancer, Vol. 81, No. 2, 08.2013, p. 180-186.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Author's reply. / Kristensen, Lasse S; Hansen, Lise Lotte; Lade-Keller, Johanne; Riber-Hansen, Rikke; Steiniche, Torben; Hager, Henrik; Guldberg, Per.
In: The Journal of molecular diagnostics : JMD, Vol. 15, No. 4, 07.2013, p. 536-7.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate › Research
The challenges of comparing a clinically validated test to other methods. / Palma, John F; Shieh, Felice; Kristensen, Lasse Sommer; Hansen, Lise Lotte; Lade-Keller, Johanne; Riber-Hansen, Rikke; Steiniche, Torben; Hager, Henrik; Guldberg, Per.
In: Journal of Molecular Diagnostics, Vol. 15, No. 4, 07.2013, p. 535-537.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Evaluation of BRAF mutation testing methodologies in formalin-fixed, paraffin-embedded cutaneous melanomas. / Lade-Keller, Johanne; Rømer, Kirsten M; Guldberg, Per; Riber-Hansen, Rikke; Hansen, Lise Lotte; Steiniche, Torben; Hager, Henrik; Kristensen, Lasse S.
In: The Journal of molecular diagnostics : JMD, Vol. 15, No. 1, 01.2013, p. 70-80.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Chromosome 1q25.3 copy number alterations in primary breast cancers detected by multiplex ligation-dependent probe amplification and allelic imbalance assays and its comparison with fluorescent in situ hybridization assays. / Wiechec, Emilia; Overgaard, Jens; Kjeldsen, Eigil; Hansen, Lise Lotte.
In: Cellular oncology (Dordrecht), Vol. Apr;36, No. 2, 2013, p. 113-120.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing. / Kristensen, Lasse Sommer; Treppendahl, Marianne Bach; Asmar, Fazila; Girkov, Mia Seremet; Nielsen, Helene Myrtue; Kjeldsen, Tina Ellegaard; Ralfkiaer, Elisabeth; Hansen, Lise Lotte; Grønbæk, Kirsten.
In: Scientific Reports, Vol. 3, 2013, p. 2789.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A new workflow for methylation biomarker development : discovery and validation of 20 novel breast cancer methylation biomarkers. / Damsgaard, Tine Engberg; Wojdacz, Tomasz K; Thestrup, Britta Boserup; Overgaard, Jens; Hansen, Lise Lotte.
2012. Abstract from AACR Annual Meeting 2012, Chicago, .Research output: Contribution to conference › Conference abstract for conference › Research
Competitive amplification of differentially melting amplicons (CADMA) enables sensitive and direct detection of all mutation types by high-resolution melting analysis. / Kristensen, Lasse Sommer; Andersen, Gitte B; Hager, Henrik; Hansen, Lise Lotte.
In: Human Mutation, Vol. 33, No. 1, 2012, p. 264-71.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer. / Kristensen, Lasse Sommer; Kjeldsen, Tina Ellegaard; Hager, Henrik; Hansen, Lise Lotte.
In: B M C Cancer, Vol. 12, 2012, p. 548.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
New drugs in melanoma provides new challenges for the pathologist. / Lade-Keller, Johanne; Kristensen, Lasse Sommer; Rømer, Kirsten; Guldberg, Per; Hager, Henrik; Riber-Hansen, Rikke; Hansen, Lise Lotte; Steiniche, Torben.
2012. Poster session presented at DPAS Årsmøde 2012, københavn, Denmark.Research output: Contribution to conference › Poster › Research
Comprehensive genome methylation analysis in bladder cancer;identification and validation of novel methylated genes and application of these as urinary tumor markers. / Reinert, Thomas; Modin, Charlotte; Mansilla Castano, Francisco; Lamy, Philippe; Wojdacz, Tomasz K; Hansen, Lise Lotte; Wiuf, Carsten; Borre, Michael; Andersen, Lars Dyrskjøt; Ørntoft, Torben Falck.
In: Clinical Cancer Research, 25.07.2011.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas : CpG island hypermethylation in colorectal cancer. / Øster, Bodil; Thorsen, Kasper; Lamy, Philippe; Wojdacz, Tomasz K; Hansen, Lise Lotte; Birkenkamp-Demtröder, Karin; Dalsgaard Sørensen, Karina; Laurberg, Søren; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.
In: International Journal of Cancer, 11.03.2011.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
High-resolution melting analysis for mutation screening of RGSL1, RGS16, and RGS8 in breast cancer. / Wiechec, Emilia; Wiuf, Carsten; Overgaard, Jens; Hansen, Lise Lotte.
In: Cancer Epidemiology, Biomarkers & Prevention, Vol. 20, No. 2, 01.03.2011, p. 397-407.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
High Resolution Melting (HRM) analysis for mutation screening of RGSL1,RGS16 and RGS8 in breast cancer. / Wiechec, Emilia; Wiuf, Carsten Henrik; Overgaard, Jens; Hansen, Lise Lotte.
In: Cancer Epidemiology, Biomarkers & Prevention, Vol. Feb;20(2), doi: 10.1158/1055-9965., 20.02.2011, p. 397-407.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Methylation of cancer related genes in tumor and peripheral blood DNA from the same breast cancer patient as two independent events. / Wojdacz, Tomasz K; Thestrup, Britta Boserup; Overgaard, Jens; Hansen, Lise Lotte.
In: Diagnostic Pathology, Vol. 6, No. 1, 2011, p. 116.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
No difference in the frequency of locus-specific methylation in the peripheral blood DNA of women diagnosed with breast cancer and age-matched controls. / Wojdacz, Tomasz K; Thestrup, Britta Boserup; Cold, Søren; Overgaard, Jens; Hansen, Lise Lotte.
In: Future Oncology, Vol. 7, No. 12, 2011, p. 1451-5.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A simple way to evaluate self-designed probes for tumor specific Multiplex Ligation-dependent Probe Amplification (MLPA). / Pedersen, Kristina; Wiechec, Emilia; Madsen, Bo Eskerod; Overgaard, Jens; Hansen, Lise Lotte.
In: BMC Research Notes, Vol. 3, No. 1, 2010, p. 179.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Increased sensitivity of KRAS mutation detection by high-resolution melting analysis of COLD-PCR products. / Kristensen, Lasse S; Daugaard, Iben Lyster; Christensen, Mariann; Hamilton-Dutoit, Stephen; Hager, Henrik; Hansen, Lise Lotte.
In: Human Mutation, Vol. 31, No. 12, 2010, p. 1366-73.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Limitations and advantages of MS-HRM and bisulfite sequencing for single locus methylation studies. / Wojdacz, Tomasz K; Møller, Tine Hørning; Thestrup, Britta Boserup; Kristensen, Lasse Sommer; Hansen, Lise Lotte.
In: Expert Review of Molecular Diagnostics, Vol. 10, No. 5, 2010, p. 575-580.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Methylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNP. / Kristensen, Lasse Sommer; Nielsen, Helene Myrtue; Hager, Henrik; Hansen, Lise Lotte.
In: Lung Cancer, 2010.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
NimbleGen arrays and LightCycler 480 system: A complete workflow for DNA methylation biomarker discovery and validation. / Wojdacz, Tomasz K; Windeløv, Johanne Agerlin; Thestrup, Britta Boserup; Overgaard, Jens; Hansen, Lise Lotte.
In: Roche Application Note, 2010.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research
Frontiers in Bioscience. / Hansen, Lise Lotte (Editor).
Mangler titel. PO Box 160 Albertson, NY 11507-0160 USA, 2009.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research
Epigenetics and cancer treatment. / Kristensen, Lasse Sommer; Myrtue Nielsen, Helene; Hansen, Lise Lotte.
In: European Journal of Pharmacology, Vol. 625, No. 1 - 3, 2009, p. 131 - 142.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Methylation-Sensitive High Resolution Melting (MS-HRM) on the LightCycler 480 System. / Wojdacz, Tomasz K; Hansen, Lise Lotte.
In: LightCycler Real-Time PCR Systems. Application Manual, 2009, p. 126-133.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research
PCR-based methods for detecting single-locus DNA methylation biomarkers in cancer diagnostics, prognostics, and response to treatment. / Kristensen, Lasse Sommer; Hansen, Lise Lotte.
In: Clinical Chemistry, Vol. 55, No. 8, 2009, p. 1471-83.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Primer design versus PCR bias in methylation independent PCR amplifications. / Wojdacz, Tomasz K; Borgbo, Tanni Kjær; Hansen, Lise Lotte.
In: Epigenetics, Vol. 4, No. 4, 2009, p. 231 234.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM. / Kristensen, Lasse Sommer; Wojdacz, Tomasz K; Thestrup, Britta Boserup; Wiuf, Carsten Henrik; Hager, Henrik; Hansen, Lise Lotte.
In: B M C Cancer, Vol. 9, No. 453, 2009, p. 453.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The effect of genetic variability on drug response in conventional breast cancer treatment. / Wiechec, Emilia; Hansen, Lise Lotte.
In: European Journal of Pharmacology, Vol. 625, No. 1 -3, 2009, p. 122 - 130.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
A fragile site within the HPC1 region at 1q25.3 affecting RGS16, RGSL1 and RGSL2 in human breast carcinomas. / Wiechec, Emilia; Overgaard, Jens; Hansen, Lise Lotte.
In: Genes, Chromosomes & Cancer, Vol. 47, 2008, p. 766-780.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A new approach to primer design for the control of PCR bias in methylation studies. / Wojdacz, Tomasz K; Hansen, Lise Lotte; Dobrovic, Alexander.
In: BMC Research Notes, Vol. 1, No. 54, 2008.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Akt mediated phosphorylation of CDK2 regulates its dual role in cell cycle and apoptosis. / Maddika, S; Ande, SR; Wiechec, Emilia; Hansen, Lise Lotte; Wesselborg, Sebastian; Los, M.
In: Journal of Cell Science, Vol. 121, 2008, p. 979-88.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer. / Madsen, Bo Eskerod; Ramos, Eliana Marisa; Boulard, Mathieu; Duda, Katarzyna; Overgaard, Jens; Nordsmark, Marianne; Wiuf, Carsten; Hansen, Lise Lotte.
In: P L o S One, Vol. 3, No. 6, 2008, p. e2492.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Methylation-sensitive high-resolution melting. / Wojdacz, Tomasz K; Dobrovic, Alexander; Hansen, Lise Lotte.
In: Nature Protocols (Print), Vol. 3, No. 12, 2008, p. 1903.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Conflicting results in SNP genotype assessment. / Hansen, Lise Lotte; Madsen, Bo Eskerod; Pedersen, Kristina; Wiuf, Carsten.
In: BioTechniques, No. 43, 2007, p. 756-762.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Predisposition to, prognosis and treatment regime for breast cancer using genetic markers on chromosome 13. / Hansen, Lise Lotte (Inventor); Overgaard, Jens (Inventor).
Patent No.: 60/884,980.Research output: Patent
Predisposition to, prognosis for and treatment of breast cancer relating to human chromosome 1 (absence). / Hansen, Lise Lotte (Inventor); Overgaard, Jens (Inventor).
Patent No.: PA 2007 00059.Research output: Patent
Predisposition to, prognosis for and treatment of breast cancer relating to human chromosome 1 (presence). / Hansen, Lise Lotte (Inventor); Overgaard, Jens (Inventor).
Patent No.: PA 2007 00060.Research output: Patent
Predisposition to, prognosis for and treatment of breast cancer relating to human chromosome 16. / Hansen, Lise Lotte (Inventor); Overgaard, Jens (Inventor).
Patent No.: PA 2007 00052.Research output: Patent
Predisposition to, prognosis for and treatment of breast cancer using genetic markers on chromosome 13. / Hansen, Lise Lotte (Inventor); Overgaard, Jens (Inventor).
Patent No.: PA 2007 00057.Research output: Patent
Predisposition to, prognosis for and treatment regime for breast cancer relating to human chromosome 16. / Hansen, Lise Lotte (Inventor); Overgaard, Jens (Inventor).
Patent No.: 60/884,975.Research output: Patent
LOH rather than genotypes of TP53 codon 72 is associated with disease-free survival in primary breast cancer. / Kyndi, Marianne; Alsner, Jan; Hansen, Lise Lotte; Sørensen, Flemming Brandt; Overgaard, Jens.
In: Acta oncologica (Stockholm, Sweden), Vol. 45, No. 5, 2006, p. 602-609.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: Towards personalized medicine. / Anderson, Judy E.; Hansen, Lise Lotte; Mooren, Frank C.; Post, Markus; Hug, Hubert; Zuse, Anne.
In: Drug Resistance Updates, Vol. 9, 2006, p. 198 - 210.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Molecular Diagnosis of Breast Cancer. / Hansen, Lise Lotte.
Prevention and Treatment of Age Related Diseases. ed. / Suresh Rattan Rattan; Moustapha Kassem. The Netherlands : Springer, 2006. p. 201-234.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research
Reversal of PCR bias for improved sensitivity of the DNA methylation melting curve assay. / Wojdacz, Tomasz Kazimierz; Hansen, Lise Lotte.
In: BioTechniques, Vol. 41, 2006, p. 274-278.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Techniques used in studies of age-related DNA methylation changes. / Wojdacz, Tomasz; Hansen, Lise Lotte.
In: New York Academy of Sciences. Annals, Vol. 1067, 2006, p. 479-487.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Familial cancer associated with a polymorphism in ARLTS1. / Calin, G.A.; Trapasso, F.; Shimizu, M.; Dumitru, C.D.; Yendamuri, S.; Godwin, A.K.; Ferracin, M.; Bernardi, G.; Chatterjee, D.; Baldassarre, G.; Rattan, S.; Alder, H.; Mabuchi, H.; Shiraishi, T.; Hansen, Lise Lotte; Overgaard, Jens; Herlea, V.; Mauro, F.R.; Dighiero, G.; Movsas, B.; Rassenti, L.; Kipps, T.; Baffa, R.; Fusco, A.; Mori, M.; Russo, G.; Liu, C.-G.; Neuberg, D.; Bullrich, F.; Negrini, M.; Croce, C.M.
In: N. Engl. J. Med., Vol. 352, No. 16, 21.04.2005, p. 1667-1676.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Familial cancer associated with a polymorphism in ARLTS1. / Calin, George Adrian; Trapasso, Francesco; Shimizu, Masayoshi; Dumitru, Calin Dan; Yendamuri, Sai; Godwin, Andrew K; Ferracin, Manuela; Bernardi, Guido; Chatterjee, Devjani; Baldassarre, Gustavo; Rattan, Shashi; Alder, Hansjuerg; Mabuchi, Hideaki; Shiraishi, Takeshi; Hansen, Lise Lotte; Overgaard, Jens; Herlea, Vlad; Mauro, Francesca Romana; Dighiero, Guillaume; Movsas, Benjamin; Rassenti, Laura; Kipps, Thomas; Baffa, Raffaele; Fusco, Alfredo; Mori, Masaki; Russo, Giandomenico; Liu, Chang-Gong; Neuberg, Donna; Bullrich, Florencia; Negrini, Massimo; Croce, Carlo M.
In: The New England Journal of Medicine, Vol. 352, No. 16, 21.04.2005, p. 1667-76.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Deconstructing PTI-1: PTI-1 is a truncated, but not mutated, form of translation elongatin factor 1A1, eEF1A1. / Mansilla, F.; Hansen, Lise Lotte; Jakobsen, H.; Kjeldgaard, N.O.; Clark, B.F.C.; Knudsen, C.R.
In: Biochim. Biophys. Acta., Vol. 1727, No. 2, 14.02.2005, p. 116-124.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Prognostic value of genotypes and LOH at TP53 codon 72 and TP53 mutations in primary breast cancer. / Kyndi, Marianne; Alsner, Jan; Hansen, Lise Lotte; Sørensen, Flemming Brandt; Overgaard, Jens.
2005. Poster session presented at The Third International Symposium on the Molecular Biology of Breast Cancer, Molde, Norway.Research output: Contribution to conference › Poster › Research
Prognostic value of genotypes and LOH at TP53 codon 72 and TP53 mutations in primary breast cancer. / Kyndi, Marianne; Alsner, Jan; Hansen, Lise Lotte; Sørensen, Flemming Brandt; Overgaard, Jens.
In: Breast Cancer Research (Online Edition), Vol. 7, No. Suppl 2, 2005, p. P4.49 .Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research
Betaine, a faciliator of PCR amplification of CG rich and repetitive regions : a facilitator of PCR amplificaiton of GC rich and repetitive regions. / Hansen, L.L.; Justesen, Just.
In: Biosystems Solutions, Vol. 9, 2004, p. 26-27.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research
Sensitive and fast mutation detection by solid-phase chemical cleavage of mismatches. / Hansen, Lise Lotte; Justesen, Just; Lambrinakos, Andrea; Cotton, Richard GH.
PCR Primer: A Laboratory Manual. ed. / Carl W Dieffenbach; Gabriela S Dveksler. Second edition. ed. USA : Cold Spring Harbor Laboratory Press, 2003. p. 265-280.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review
A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene. / Smidt, Kamille C J; Hansen, Lise Lotte; Søgaard, T Max M; Petersen, Lone K; Knudsen, Ulla B; Martensen, Pia M.
In: B B A - Proteins and Proteomics, Vol. 1638, No. 3, 30.07.2003, p. 227-34.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene. / Smidt, Kamille; Hansen, Lise Lotte; Søgaard, T Max M; Petersen, Lone Kjeld; Knudsen, Ulla Breth; Martensen, Pia Møller.
In: BBA General Subjects, Vol. 1636, No. 3, 30.07.2003, p. 227-234.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Loss of heterozygosity, a multiplex PCR method to define narrow deleted chromosomal regions of a tumor genome. / Hansen, L. L.; Justesen, J.; Dieffenbach, C.W. (Editor); Dveksler, G.S. (Editor).
PCR Primer: A Laboratory Manual. ed. / Carl W. Dieffenbach; Gabriela S. Dveksler. Vol. 1 second Edition. ed. Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, 2003. p. 223-236.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research
PCR amplification of highly GC-rich regions. / Hansen, Lise Lotte; Justesen, Just; Dieffenbach, C.W. (Editor); Dveksler, G.S. (Editor).
PCR Primer: A Laboratory Manual. New York : Cold Spring Harbor Laboratory Press, 2003. p. -.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Communication
Allelic imbalance in selected chromosomal regions in ovarian cancer. / Hansen, Lise Lotte; Jensen, Lise Lind; Dimitrakakis, Constantine; Michalas, Stylianos; Gilbert, Fred; Barber, Hugh R.K.; Overgaard, Jens; Arzimanoglou, lordanis I.
In: Cancer Genetics and Cytogenetics, Vol. 139, No. 1, 11.2002, p. 1-8.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Frequent LOH at hMLH1, a highly variable SNP in hMSH3, and negligible coding instability in ovarian cancer. / Arzimanoglou, I.I.; Hansen, L.L.; Chong, D.; Li, Z.; Psaroudi, M.C.; Dimitrakakis, C.; Jacovina, A.T.; Shevchuk, M.; Reid, L.; Hajjar, K.A.; Vassilaros, S.; Michalas, S.; Gilbert, F.; Chervenak, F.A.; Barber, H.R.
In: Anticancer Res, Vol. 22, No. 2A, 03.2002, p. 969-975.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment of human NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 (NDUFB3) and of its four pseudogenes to human chromosomes 2q31.3, 1p13.3→p13.1, 9q32→q34.1, 14q22.3→q23.1 and 14q32.2 by radiation hybrid mapping. / Jensen, L. L.; Nielsen, M. M.; Justesen, J.; Hansen, Lise Lotte.
In: Cytogenetics and Cell Genetics, Vol. 93, No. 1-2, 20.08.2001, p. 147-150.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment of human NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 (NDUFB3) and of its four pseudogenes to human chromosomes 2q31.3, 1p13.3 → p13.1, 9q32 → q34.1, 14q22.3 → q23.1 and 14q32.2 byradiation hybrid mapping. / Jensen, L.L.; Nielsen, M.M.; Justesen, Just; Hansen, Lise Lotte.
In: Cytogenetic and Genome Research, Vol. 93, 2001, p. 147-150.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients. / Alsner, Jan; Yilmaz, M; Guldberg, P; Hansen, Lise Lotte; Overgaard, J.
In: Clinical Cancer Research, Vol. 6, No. 10, 10.2000, p. 3923-31.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
TP53 mutation is an independent prognostic marker for poor outcome in both node-negative and node-positive breast cancer. / Overgaard, J; Yilmaz, M; Guldberg, P; Hansen, Lise Lotte; Alsner, J.
In: Acta oncologica (Stockholm, Sweden), Vol. 39, No. 3, 2000, p. 327-33.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1tq14.3 and the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32q34.1 with radiationhybrid mapping. / Hansen, Lise Lotte; Jørgensen, R.; Justesen, Just.
In: Cytogenetic and Genome Research, Vol. 88, 2000, p. 91-92.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1→q14.3 and of the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32→q34.1 with radiationhybrid mapping. / Hansen, L.L.; Jørgensen, R.; Justesen, J.
In: Cytogenetic and Genome Research, Vol. 88, No. 1-2, 2000, p. 91-92.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment(1) of the human postmeiotic segretation increased ( S. cerevisiae) 1 (PMS1) to chromosome 2q31.1 by radiation hybrid mapping. / Alvarez Soria, M.A.; Justesen, Just; Hansen, Lise Lotte.
In: Cytogenetic and Genome Research, Vol. 88, 2000, p. 200-201.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment1 of the human postmeiotic segregation increased (S. cerevisiae) (PMS1) to chromosome 2q31.1 by radiation hybrid mapping. / Alvarez Soria, M.A.; Justesen, J.; Hansen, L.L.
In: Cytogenetic and Genome Research, Vol. 88, No. 3-4, 2000, p. 200-201.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The prognostic value of allelic imbalance at chromosome 16q in primary breast cancer. / Hansen, L.; Pandalai, S.G. (Editor).
Recent Research Development in Cancer. ed. / S. G. Pandalai. Vol. 2 Trivandrum-695 008, India : Transworld Research Network, 2000. p. 167-182.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research
Assignment of the human mitochondrial tryptophanyl-tRNA syntetase (WARS2) to 1p13.1-p13.3. by radiation hybrid mapping. / Martinez-Dominguez, T.M.; Justesen, J.; Kruse, T.A.; Hansen, L.L.
In: Cytogenetics & Cell Genet, Vol. 83, No. 3-4, 1999, p. 249-250.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment of the human peptide chain release factor 3 (GSPT2) to Xp11.23 p11.21 and of the distal marker DXS1039 by radiation hybrid mapping. / Hansen, Lise Lotte; Jakobsen, C.G.; Justesen, Just.
In: Cytogenetic and Genome Research, Vol. 86, 1999, p. 250-251.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment of the human translation termination factor 1 (ETF1) to 5q31.1 and of the proximal marker D5S1995 by radiation hybrid mapping. / Hansen, Lise Lotte; Jakobsen, C G; Justesen, Just.
In: Cytogenetic and Genome Research, Vol. 87, No. 3-4, 1999, p. 256-257.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Assignment1 of the human peptide chain release factor 3 (GSPT2) to Xp11.23 → p11.21 and of the distal marker DXS1039 by radiation hybrid mapping. / Hansen, L.L.; Jakobsen, C.G.; Justesen, J.
In: Cytogenetic and Genome Research, Vol. 86, 1999, p. 250-251.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Structure of the human CpG-island-containing lung Kruppel-like factor (LKLF) gene and its location in chromosome 19p13.11-13 locus. / Kozyrev, S.V.; Hansen, L.L.; Poltaraus, A.B.; Domninsky, D.A.; Kisselev, L.L.
In: F E B S Letters, Vol. 448, No. 1, 1999, p. 149-152.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Allelic loss of 16q23.2-24.2 is an independent marker of good prognosis in primary breast cancer. / Hansen, Lise Lotte; Yilmaz, M; Overgaard, J; Andersen, J; Kruse, T A.
In: Cancer Research, Vol. 58, No. 10, 1998, p. 2166-9.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Molecular genetic analysis of easily accessible breast tumour DNA, purified from tissue left over from hormone receptor measurement. / Hansen, Lise Lotte; Andersen, J; Overgaard, J; Kruse, T A.
In: Acta Pathologica Microbiologica et Immunologica Scandinavica, Vol. 106, No. 3, 1998, p. 371-7.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Refined localization of the pyruvate dehydrogenase E1 alpha gene (PDHA1) by linkage analysis. / Børglum, A D; Flint, T; Hansen, Lise Lotte; Kruse, T A.
In: Human Genetics, Vol. 99, No. 1, 1997, p. 80-2.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Sensitive and fast mutation detection by solid phase chemical cleavage. / Hansen, Lise Lotte; Justesen, Just; Kruse, Torben A.
In: Human Mutation, Vol. 7 , No. 3, 1996, p. 256-263.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review