Aarhus University Seal / Aarhus Universitets segl

Lisbeth Schmidt Laursen

  1. 2000
  2. Published

    Expression of recombinant human pregnancy-associated plasma protein A and identification of the proform of eosinophil major basic protein as its physiological inhibitor. / Overgaard, M.T.; Haaning, J.; Boldt, H.B.; Olsen, I.M.; Laursen, L.S.; Christiansen, M.; Gleich, G.J.; Sottrup-Jensen, L.; Conover, C.A.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 275, No. 40, 2000, p. 31128-31133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2001
  4. Published

    Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin. / Boldt, H B; Overgaard, M T; Laursen, L S; Weyer, K; Sottrup-Jensen, L; Oxvig, C; Weyer, Kathrin.

    In: Biochemical Journal, Vol. 358, No. Pt 2, 01.09.2001, p. 359-367.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A. / Laursen, L.S.; Overgaard, M.T.; Soe, R.; Boldt, H.B.; Sottrup-Jensen, L.; Giudice, L.C.; Conover, C.A.; Oxvig, C.

    In: F E B S Letters, Vol. 504, 2001, p. 36-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase. / Overgaard, M.T.; Boldt, H.B.; Laursen, L.S.; Sottrup-Jensen, L.; Conover, C.A.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 276, 2001, p. 21849-21853.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. 2002
  8. Published

    Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats. / Laursen, Lisbeth S; Overgaard, Michael T; Weyer, Kathrin; Boldt, Henning B; Ebbesen, Peter; Christiansen, Michael; Sottrup-Jensen, Lars; Giudice, Linda C; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 277, No. 49, 06.12.2002, p. 47225-34.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Substrate specificity of the metalloproteinase PAPP-A assessed by mutagenesis and analysis of synthetic peptides. Substrate residues distant from the scissile bond are critical for proteolysis. / Laursen, L.S.; Overgaard, M.T.; Nielsen, C.G.; Boldt, H.B.; Hopman, K.H.; Enghild, J.J.; Conover, C.A.; Sottrup-Jensen, L.; Giudice, L.C.; Oxvig, C.

    In: Biochem. J., Vol. 367, 2002, p. 31-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity. / Søe, R.; Overgaard, M.T.; Thomsen, A.R.; Laursen, L.S.; Olsen, I.M.; Sottrup-Jensen, L.; Haaning, J.; Giudice, L.C.; Conover, C.A.; Oxvig, C.

    In: European Journal of Biochemistry, Vol. 269, 2002, p. 2247-2256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. 2004
  12. Published

    Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module. / Weyer, Kathrin; Overgaard, M T; Laursen, Lisbeth Schmidt; Nielsen, Claus Gyrup; Schmitz, Alexander; Christiansen, M; Sottrup-Jensen, Lars; Giudice, L C; Oxvig, Claus.

    In: F E B S Journal, Vol. 271, 2004, p. 1525-1535.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. 2005
  14. Published

    Real-time measurement in living cells of insulin-like growth factor activity using bioluminescence resonance energy transfer. / Laursen, Lisbeth Schmidt; Oxvig, Claus.

    In: Biochemical Pharmacology, Vol. 69, 2005, p. 1723-1733.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. 2007
  16. Published

    Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor. / Glerup, Simon; Kløverpris, Søren; Laursen, Lisbeth S; Dagnaes-Hansen, Frederik; Thiel, Steffen; Conover, Cheryl A.; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 282, No. 3, 19.01.2007, p. 1769-1778.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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