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Lisa Maria Wu

Pre-bereavement meaning and post-bereavement distress in mothers of children who underwent haematopoietic stem cell transplantation

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review


  • Lisa Wu
  • George Bonanno
  • ,
  • Katherine N DuHamel
  • ,
  • William H Redd
  • ,
  • Christine Rini
  • ,
  • Jane Austin
  • ,
  • Nancy Nereo
  • ,
  • Jamie Ostroff
  • ,
  • Susan Parsons
  • ,
  • Richard Martini
  • ,
  • Sharon Williams
  • ,
  • Laura Mee
  • ,
  • Sandra Sexson
  • ,
  • Sharon Manne

OBJECTIVES: The purpose of this study was to explore the association of meaning-making with psychological adjustment to bereavement among mothers of children who had undergone haematopoietic stem cell transplantation (HSCT).

DESIGN: A prospective research design was used. Regression analyses were conducted to determine the relations between pre-bereavement variables (distress, searching for meaning, and finding meaning) and distress post-bereavement.

METHODS: Thirty-five mothers of children who had undergone HSCT were interviewed at the time of their child's HSCT and 3 months post-bereavement.

RESULTS: Mothers who reported searching for meaning at HSCT reported greater post-bereavement distress, and mothers who reported finding meaning at HSCT reported less post-bereavement distress. Distress at HSCT and the number of days between the time of death and the post-bereavement time point were also found to be significant predictors of post-bereavement distress.

CONCLUSIONS: This study provides partial support for the role of meaning in adjustment to loss.

Original languageEnglish
JournalBritish Journal of Health Psychology
IssuePt 3
Pages (from-to)419-33
Number of pages15
Publication statusPublished - Sept 2008
Externally publishedYes

    Research areas

  • Anxiety/diagnosis, Attitude to Health, Bereavement, Child, Depression/diagnosis, Female, Hematopoietic Stem Cell Transplantation, Humans, Male, Mothers/psychology, Prospective Studies, Severity of Illness Index, Time Factors

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