Line Reinert

  1. 2019
  2. Published

    DNA-stimulated cell death : implications for host defence, inflammatory diseases and cancer. / Paludan, Søren R.; Reinert, Line S.; Hornung, Veit.

    In: Nature Reviews Immunology, Vol. 19, No. 3, 01.03.2019, p. 141-153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  3. 2018
  4. Published

    High-dose vitamin D3 supplementation decreases the number of colonic CD103+ dendritic cells in healthy subjects. / Bak, Nina Friis; Bendix, M; Hald, S; Reinert, L; Magnusson, M K; Agnholt, J.

    In: European Journal of Nutrition, Vol. 57, No. 7, 10.2018, p. 2607-2619.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. / Prabakaran, Thaneas; Bodda, Chiranjeevi; Krapp, Christian; Zhang, Bao-Cun; Christensen, Maria H; Sun, Chenglong; Reinert, Line; Cai, Yujia; Jensen, Søren B; Skouboe, Morten K; Nyengaard, Jens R; Thompson, Craig B; Lebbink, Robert Jan; Sen, Ganes C; van Loo, Geert; Nielsen, Rikke; Komatsu, Masaaki; Nejsum, Lene N; Jakobsen, Martin R; Gyrd-Hansen, Mads; Paludan, Søren R.

    In: E M B O Journal, Vol. 37, No. 8, E97858, 13.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice. / Skouboe, Morten K; Knudsen, Alice; Reinert, Line S; Boularan, Cedric; Lioux, Thierry; Perouzel, Eric; Thomsen, Martin K; Paludan, Søren R.

    In: P L o S Pathogens, Vol. 14, No. 4, e1006976, 02.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. 2017
  8. Published

    Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer. / Thomsen, Mathilde Borg Houlberg; Nordentoft, Iver; Lamy, Philippe; Vang, Søren; Reinert, Line; Mapendano, Christophe Kamungu; Høyer, Søren; Ørntoft, Torben F; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: Scientific Reports, Vol. 7, No. 1, 15.09.2017, p. 11702.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2016
  10. Published

    Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. / Reinert, Line S; Lopušná, Katarína; Winther, Henriette; Sun, Chenglong; Thomsen, Martin K; Nandakumar, Ramya; Mogensen, Trine H; Meyer, Morten; Vægter, Christian; Nyengaard, Jens R; Fitzgerald, Katherine A; Paludan, Søren R.

    In: Nature Communications, Vol. 7, 13348, 10.11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Gene-environmental interactions between genetic variants in antiviral response genes and prenatal maternal infections in schizophrenia. / Manikandan, Veera; Reinert, Line; Paludan, Søren Riis; Grove, Jakob; Nielsen, Philip Finn Rising; Hougaard, David M.; Nordentoft, Merete; Werge, Thomas; Børglum, Anders; Mortensen, Preben Bo; Demontis, Ditte.

    2016. Poster session presented at American Society of Human Genetics 2016, Vancouver, Canada.

    Research output: Contribution to conferencePosterResearch

  12. Published

    HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression. / Christensen, Maria H.; Jensen, Søren B.; Miettinen, Juho J.; Luecke, Stefanie; Prabakaran, Thaneas; Reinert, Line S.; Mettenleiter, Thomas; Chen, Zhijian J.; Knipe, David M.; Sandri-Goldin, Rozanne M.; Enquist, Lynn W.; Hartmann, Rune; Mogensen, Trine H.; Rice, Stephen A.; Nyman, Tuula A.; Matikainen, Sampsa; Paludan, Søren R.

    In: The EMBO Journal, Vol. 35, No. 13, 01.07.2016, p. 1385-1399.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection. / Thomsen, Martin K; Nandakumar, Ramya; Stadler, Daniela; Malo, Antje; Valls, Roser Marin; Wang, Fan; Reinert, Line S; Dagnaes-Hansen, Frederik; Hollensen, Anne Kruse; Mikkelsen, Jacob Giehm; Protzer, Ulrike; Paludan, Søren R.

    In: Hepatology, Vol. 64, No. 3, 16.06.2016, p. 746-759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2015
  15. Published

    An innate antiviral pathway acting before interferons at epithelial surfaces. / Iversen, Marie B; Reinert, Line S; Thomsen, Martin K; Bagdonaite, Ieva; Nandakumar, Ramya; Cheshenko, Natalia; Prabakaran, Thaneas; Vakhrushev, Sergey Y; Krzyzowska, Malgosha; Kratholm, Sine K; Ruiz-Perez, Fernando; Petersen, Steen V; Goriely, Stanislas; Bibby, Bo Martin; Eriksson, Kristina; Ruland, Jürgen; Thomsen, Allan R; Herold, Betsy C; Wandall, Hans H; Frische, Sebastian; Holm, Christian K; Paludan, Søren R.

    In: Nature Immunology, 30.11.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    NKT cell activation by local α-galactosylceramide administration decreases susceptibility to HSV-2 infection. / Iversen, Marie Beck; Jensen, Simon Kok; Hansen, Anne Louise; Winther, Henriette; Issazadeh-Navikas, Shohreh; Reinert, Line; Holm, Christian Kanstrup.

    In: Immunobiology, 21.01.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Functional IRF3 deficiency in a patient with herpes simplex encephalitis. / Andersen, Line Lykke; Mørk, Nanna; Reinert, Line S; Kofod-Olsen, Emil; Narita, Ryo; Jørgensen, Sofie E; Skipper, Kristian A; Höning, Klara; Gad, Hans Henrik; Østergaard, Lars; Ørntoft, Torben F; Hornung, Veit; Paludan, Søren R; Mikkelsen, Jacob Giehm; Fujita, Takashi; Christiansen, Mette; Hartmann, Rune; Mogensen, Trine H.

    In: Journal of Experimental Medicine, Vol. 212, No. 9, 2015, p. 1371-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2014
  19. Published

    TRAM is required for TLR2 endosomal signaling to type I IFN induction. / Stack, Julianne; Doyle, Sarah L; Connolly, Dympna J; Reinert, Line S; O'Keeffe, Kate M; McLoughlin, Rachel M; Paludan, Søren R; Bowie, Andrew G.

    In: Journal of Immunology, Vol. 193, No. 12, 15.12.2014, p. 6090-102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2013
  21. Published

    Interleukin-21 Receptor Signalling Is Important for Innate Immune Protection against HSV-2 Infections. / Kratholm, Sine K; Iversen, Marie B; Reinert, Line; Jensen, Simon K; Hokland, Marianne; Andersen, Thomas; Rankin, Andrew; Young, Deborah; Frische, Sebastian; Paludan, Søren R; Holm, Christian K.

    In: PLOS ONE, Vol. 8, No. 12, 2013, p. e81790.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2012
  23. Published

    Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection. / Vibholm, Line; Reinert, Line S; Søgaard, Ole S; Paludan, Søren R; Østergaard, Lars Jørgen; Tolstrup, Martin; Melchjorsen, Jesper.

    In: AIDS Research and Human Retroviruses, Vol. 28, No. 11, 2012, p. 1404-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. / Reinert, Line S; Harder, Louis; Holm, Christian K; Iversen, Marie Beck; Horan, Kristy A; Dagnæs-Hansen, Frederik; Ulhøi, Benedicte P; Holm, Thomas H; Mogensen, Trine H; Owens, Trevor; Nyengaard, Jens R; Thomsen, Allan Randrup; Paludan, Søren Riis.

    In: Journal of Clinical Investigation, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. 2009
  26. Published

    Innate recognition of intracellular pathogens: detection and activation of the first line of defense. / Rasmussen, Simon B; Reinert, Line; Paludan, Søren R.

    In: A P M I S Supplementum, Vol. 117, No. 5-6, 01.05.2009, p. 323-37.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. 2008
  28. Published

    TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain. / Sørensen, Louise Nørgaard; Reinert, Line; Malmgaard, Lene; Bartholdy, Christina; Thomsen, Allan Randrup; Paludan, Søren Riis.

    In: Journal of Immunology, Vol. 181, 2008, p. 8604-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain. / Sørensen, Louise N; Reinert, Line S; Malmgaard, Lene; Bartholdy, Christina; Thomsen, Allan Randrup; Paludan, Søren Riis.

    In: Journal of Immunology, Vol. 181, No. 12, 2008, p. 8604-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2007
  31. Published

    Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations : a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer. / Nielsen, Karsten Bork; Sørensen, Suzette; Cartegni, Luca; Corydon, Thomas Juhl; Doktor, Thomas Koed; Schroeder, Lisbeth Dahl; Reinert, Line Sinnathamby; Elpeleg, Orly; Krainer, Adrian R; Gregersen, Niels; Kjems, Jørgen; Andresen, Brage Storstein.

    In: American Journal of Human Genetics, Vol. 80, No. 3, 01.03.2007, p. 416-432.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Phosphorylation of MCT-1 by p44/42 MAPK is required for its stabilization in response to DNA damage. / Nandi, S; Reinert, Line; Hachem, A; Mazan-Mamczarz, K; Hagner, P; He, H; Gartenhaus, RB.

    In: Oncogene, Vol. 26, 2007, p. 2283-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. 2006
  34. Published

    A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability. / Lützelberger, Martin; Reinert, Line S; Das, Atze T; Berkhout, Ben; Kjems, Jørgen.

    In: Journal of Biological Chemistry, Vol. 281, No. 27, 07.07.2006, p. 18644-18651.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Expression of DNA mismatch repair proteins in transformed non-Hodgkin's lymphoma: relationship to smoking. / Nandi, S; Yu, J; Reinert, Line; Gartenhaus, RB.

    In: Leukemia and Lymphoma, Vol. 47, 2006, p. 1806-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    MCT-1 protein interacts with the cap complex and modulates messenger RNA translational profiles. / Reinert, Line; Shi, B; Nandi, S; Mazan-Mamczarz, K; Vitolo, M; Bachman, KE; He, H; Gartenhaus, RB.

    In: Cancer Research, Vol. 66, 2006, p. 8994-9001.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. 2004
  38. Published

    Homozygosity for a severe novel medium-chain acyl-CoA dehydrogenase (MCAD) mutation IVS3-1G [Formula: see text] C that leads to introduction of a premature termination codon by complete missplicing of the MCADmRNA and is associated with phenotypic diversity ranging from sudden neonatal death to asymptomatic status. / Korman, S.H.; Gutman, A.; Brooks, R.; Sinnathamby, Thayline; Gregersen, N.; Andresen, B.S.

    In: Mol. Genet, No. Metab 82, 2004, p. 121-129.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  39. 2003
  40. Published

     A missense mutation found in patients with MCAD deficiency inactivates an exonic splicing enhancer in the MCAD gene. / Nielsen, Karsten Bork; Sinnathamby, Thayline; Cartegni, Luca; Corydon, Thomas Juhl; Kjems, Jørgen; Krainer, Adrain R; Elpeleg, Orly; Gregersen, Niels; Andresen, Brage Storstein.

    2003. Poster session presented at Annual Meeting of the RNA society, Wien, .

    Research output: Contribution to conferencePosterResearch