Lene Bastrup

Effect of early supervised progressive resistance training compared to unsupervised home-based exercise after fast-track total hip replacement applied to patients with preoperative functional limitations. A single-blinded randomised controlled trial

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Lone Ramer Mikkelsen
  • I Mechlenburg
  • K Søballe
  • L B Jørgensen
  • S Mikkelsen, Interdisciplinary Research Unit, Elective Surgery Centre, Silkeborg Regional Hospital. Electronic address: soermik@midt.rm.dk., Unknown
  • T Bandholm, Physical Medicine & Rehabilitation Research - Copenhagen (PMR-C), Department of Physiotherapy, Department of Orthopaedic Surgery and Clinical Research Centre, Copenhagen University Hospital, Hvidovre. Electronic address: Thomas.Bandholm@hvh.regionh.dk.
  • ,
  • A K Petersen

OBJECTIVE: To examine if 2 weekly sessions of supervised progressive resistance training (PRT) in combination with 5 weekly sessions of unsupervised home-based exercise is more effective than 7 weekly sessions of unsupervised home-based exercise in improving leg-extension power of the operated leg 10 weeks after total hip replacement (THR) in patients with lower pre-operative function.

METHOD: A total of 73 patients scheduled for THR were randomised (1:1) to intervention group (IG, home based exercise 5 days/week and PRT 2 days/week) or control group (CG, home based exercise 7 days/week). The primary endpoint was change in leg extension power at 10 week follow up. Secondary outcomes were isometric hip muscle strength, sit-to-stand test, stair climb test, 20 meter walking speed and patient-reported outcome (HOOS).

RESULTS: Sixty-two completed the trial (85%). Leg extension power increased from baseline to the 10 week follow up in both groups; mean [95% CI] IG: 0.29 [0.13;0.45] and CG: 0.26 [0.10;0.42]W/kg, with no between-group difference (primary outcome) (P=0.79). Maximal walking speed (P = 0.008) and stair climb performance (P = 0.04) improved more in the IG compared to CG, no other between-group differences existed.

CONCLUSIONS: In this trial, supervised PRT twice a week in addition to 5 weekly sessions of unsupervised exercise for 10 weeks was not superior to 7 weekly sessions of unsupervised home-based exercise for 10 weeks in improving the primary outcome, leg-extension power of the operated leg, at the primary endpoint 10 weeks after surgery in THR patients with lower pre-operative function.


Original languageEnglish
JournalOsteoarthritis and Cartilage
Pages (from-to)2051-2058
Number of pages8
Publication statusPublished - 2014

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