Aarhus University Seal / Aarhus Universitets segl

Lars Sottrup-Jensen

  1. 2014
  2. Published

    Crystallization and preliminary X-ray diffraction analysis of eukaryotic α2-macroglobulin family members modified by methylamine, proteases and glycosidases. / Goulas, T; Garcia-Ferrer, I; García-Piqué, S; Sottrup-Jensen, Lars; Gomis-Rüth, F X.

    In: Molecular Oral Microbiology, Vol. 29, No. 6, 01.01.2014, p. 354-364.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Purification of human complement protein c5. / Sottrup-Jensen, Lars; Andersen, Gregers Rom.

    The Complete System: Mehods and Protocols. Vol. 1100 Springer, 2014. p. 93-102 (Methods in Molecular Biology).

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  4. 2012
  5. Published

    Structural basis for activation of the complement system by component C4 cleavage. / Kidmose, Rune T; Laursen, Nick S; Dobó, József; Kjaer, Troels R; Sirotkina, Sofia; Yatime, Laure; Sottrup-Jensen, Lars; Thiel, Steffen; Gál, Péter; Andersen, Gregers Rom.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 38, 18.09.2012, p. 15425-15430.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The Crystal Structure of Human α(2) -Macroglobulin Reveals a Unique Molecular Cage. / Marrero, Aniebrys; Duquerroy, Stephane; Trapani, Stefano; Goulas, Theodoros; Guevara, Tibisay; Andersen, Gregers Rom; Navaza, Jorge; Sottrup-Jensen, Lars; Gomis-Rüth, F Xavier.

    In: Angewandte Chemie International Edition, Vol. 51, No. 14, 2012, p. 3340-44.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. 2011
  8. Published

    Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. / Laursen, Nick Stub; Andersen, Kasper Røjkjær; Braren, Ingke; Spilllner, Edzard; Sottrup-Jensen, Lars; Andersen, Gregers Rom.

    In: E M B O Journal, Vol. 30, No. 3, 02.02.2011, p. 606-616.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Synergistic activation of eIF4A by eIF4B and eIF4G. / Nielsen, Klaus Hvid; Behrens, Manja Anette; He, Yangzi; Oliveira, Cristiano Luis Pinto de; Sottrup-Jensen, Lars; Hoffmann, Søren Vrønning; Pedersen, Jan Skov; Andersen, Gregers Rom.

    In: Nucleic Acids Research, Vol. 39, No. 7, 2011, p. 2678-2689.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2010
  11. Published

    Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus. / Laursen, Nick Stub; Gordon, Natasha; Lorenz, Natalie; Jackson, Nicola; Wines, Bruce; Spillner, Edzard; Christensen, Jesper Bjerg; Jensen, Morten; Fredslund, Folmer; Bjerre, Mette; Sottrup-Jensen, Lars; Fraser, John; Andersen, Gregers Rom.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, No. 8, 2010, p. 3681-3686.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. 2008
  13. Published

    Structure of and influence of a tick complement inhibitor on human complement component 5. / Fredslund, Folmer; Laursen, Nick S; Roversi, Pietro; Jenner, Lasse Bohl; Oliveira, Cristiano L P; Pedersen, Jan S; Nunn, Miles A; Lea, Susan M; Discipio, Richard; Sottrup-Jensen, Lars; Andersen, Gregers Rom.

    In: Nature Immunology, Vol. 9, No. 7, 07.2008, p. 753-60.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Den rummelige opbygning af proteiner fra immunforsvaret. / Fredslund, Folmer; Laursen, Nick Stub; Sottrup-Jensen, Lars; Andersen, Gregers Rom.

    In: Dansk Kemi, Vol. 89, 2008, p. 44-48.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  15. 2006
  16. Published

    The structure of bovine complement component 3 reveals the basis for thioester function. / Fredslund, Folmer; Jenner, Lasse Bohl; Husted, Lise B; Nyborg, Jens; Andersen, Gregers Rom; Sottrup-Jensen, Lars.

    In: Journal of Molecular Biology, Vol. 361, No. 1, 04.08.2006, p. 115-127.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules. / Boldt, Henning Bünsow; Glerup, Simon; Overgaard, Michael Toft; Sottrup-Jensen, Lars; Oxvig, Claus.

    In: Protein Expr Purif., Vol. 48, No. 2, 2006, p. 261-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Physical Biochemistry Module 1. Introductory notes to chromatography, hydrodynamics, and HPLC. / Sottrup-Jensen, Lars.

    2006. 200 p.

    Research output: Book/anthology/dissertation/reportCompendium/lecture notesEducation

  19. 2005
  20. Published

    Introductory notes to Circular Dichroism (CD). / Sottrup-Jensen, Lars.

    2005. 60 p.

    Research output: Book/anthology/dissertation/reportCompendium/lecture notesEducation

  21. Published

    Physical Biochemistry. Laboratory course on Reverse-Phase High Performance Liquid Chromatography (RP-HPLC). / Sottrup-Jensen, Lars.

    2005. 27 p.

    Research output: Book/anthology/dissertation/reportCompendium/lecture notesEducation

  22. Published

    Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP is a multistep process of intra- and intermolecular disulfide rearrangements). / Glerup, Simon; Boldt, Henning Bünsow; Overgaard, Mikael; Sottrup-Jensen, Lars; Giudice, Linda C.; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 9823-9832.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. 2004
  24. Published

    The Lin12-Notch Repeats of Pregnancy-associated Plasma Protein-A Bind Calcium and Determine Its Proteolytic Specificity. / Boldt, Henning B; Kjaer-Sorensen, Kasper; Overgaard, Michael T; Weyer, Kathrin; Poulsen, Christine B; Sottrup-Jensen, Lars; Conover, Cheryl A; Giudice, Linda C; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 279, No. 37, 10.09.2004, p. 38525-38531.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module. / Weyer, Kathrin; Overgaard, M T; Laursen, Lisbeth Schmidt; Nielsen, Claus Gyrup; Schmitz, Alexander; Christiansen, M; Sottrup-Jensen, Lars; Giudice, L C; Oxvig, Claus.

    In: F E B S Journal, Vol. 271, 2004, p. 1525-1535.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase. / Overgaard, Michael Toft; Glerup, Simon; Boldt, Henning Bünsow; Rodacker, Vivien; Marie Olsen, Inger; Christiansen, Michael; Sottrup-Jensen, Lars; Giudice, Linda C.; Oxvig, Claus.

    In: F E B S Letters, Vol. 560, 2004, p. 147-152.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase. / Overgaard, M.T.; Glerup, S.; Boldt, H.B.; Olsen, I.M.; Christiansen, M.; Sottrup-Jensen, L.; Giudice, L.C.; Oxvig, C.

    In: F E B S Letters, Vol. 560, 2004, p. 147-152.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Pappalysin-1 (pregnancy-associated plasma protein-A). / Oxvig, C.; Overgaard, M.T.; Sottrup-Jensen, L.; Barrett, A.J. (Editor); Rawlings, N.D. (Editor); Woessner, J.F. (Editor).

    Handbook of proteolytic enzymes, 2nd ed. ISBN 0-12-079610-4. ed. London : Academic Press, 2004. p. 12259-12254.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  29. Published

    Screening for Down's syndrome in early and late first and second trimester using six maternal serum markers. / Christiansen, M.; Larsen, S.O.; Oxvig, C.; Qin, Q.-P.; Wagner, J.M.; Overgaard, M.T.; Gleich, G.J.; Sottrup-Jensen, L.; Nørgaard-Pedersen, B.

    In: Clin. Genet., Vol. 65, 2004, p. 11-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2003
  31. Published

    4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is not specific for labeling of sulfhydryl groups in proteins as it may also react with phenolic hydroxy groups and amino groups. / Husted, L.B.; Sørensen, E.S.; Sottrup-Jensen, L.

    In: Anal. Biochem., Vol. 314, 2003, p. 166-168.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  32. Published

    Complex of pregnancy-associated plasma protein-A and the proform of the eosiniphil major basic protein: Disulphide structure and carbohydrate attachment. / Overgaard, M.T.; Sørensen, E.S.; Stachowiak, D.; Boldt, H.B.; Kristensen, L.; Sottrup-Jensen, L.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 278, 2003, p. 2106-2117.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. 2002
  34. Published

    Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats. / Laursen, Lisbeth S; Overgaard, Michael T; Weyer, Kathrin; Boldt, Henning B; Ebbesen, Peter; Christiansen, Michael; Sottrup-Jensen, Lars; Giudice, Linda C; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 277, No. 49, 06.12.2002, p. 47225-34.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity. / Søe, R.; Overgaard, M.T.; Thomsen, A.R.; Laursen, L.S.; Olsen, I.M.; Sottrup-Jensen, L.; Haaning, J.; Giudice, L.C.; Conover, C.A.; Oxvig, C.

    In: European Journal of Biochemistry, Vol. 269, 2002, p. 2247-2256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Localization of carbohydrate attachment sites and disulfide bridges in limulus alpha 2-macroglobulin. Evidence for two forms differing primarily in their bait region sequences. / Husted, L.B.; Sørensen, E.S.; Armstrong, P.B.; Quigley, J.P.; Kristensen, L.; Sottrup-Jensen, L.

    In: Journal of Biological Chemistry, Vol. 277, No. 46, 2002, p. 43698-43706.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Substrate specificity of the metalloproteinase PAPP-A assessed by mutagenesis and analysis of synthetic peptides. Substrate residues distant from the scissile bond are critical for proteolysis. / Laursen, L.S.; Overgaard, M.T.; Nielsen, C.G.; Boldt, H.B.; Hopman, K.H.; Enghild, J.J.; Conover, C.A.; Sottrup-Jensen, L.; Giudice, L.C.; Oxvig, C.

    In: Biochem. J., Vol. 367, 2002, p. 31-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2001
  39. Published

    Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin. / Boldt, H B; Overgaard, M T; Laursen, L S; Weyer, K; Sottrup-Jensen, L; Oxvig, C; Weyer, Kathrin.

    In: Biochemical Journal, Vol. 358, No. Pt 2, 01.09.2001, p. 359-367.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A. / Laursen, L.S.; Overgaard, M.T.; Soe, R.; Boldt, H.B.; Sottrup-Jensen, L.; Giudice, L.C.; Conover, C.A.; Oxvig, C.

    In: F E B S Letters, Vol. 504, 2001, p. 36-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase. / Overgaard, M.T.; Boldt, H.B.; Laursen, L.S.; Sottrup-Jensen, L.; Conover, C.A.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 276, 2001, p. 21849-21853.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 2000
  43. Published

    Expression of recombinant human pregnancy-associated plasma protein A and identification of the proform of eosinophil major basic protein as its physiological inhibitor. / Overgaard, M.T.; Haaning, J.; Boldt, H.B.; Olsen, I.M.; Laursen, L.S.; Christiansen, M.; Gleich, G.J.; Sottrup-Jensen, L.; Conover, C.A.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 275, No. 40, 2000, p. 31128-31133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    The status of half-cystine residues and locations of N-glycosylated asparagine residues in human eosinophil peroxidase. / Thomsen, A.R.; Sottrup-Jensen, L.; Gleich, G.J.; Oxvig, C.

    In: Arch. Biochem. Biophys., Vol. 379, No. 1, 2000, p. 147-152.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. 1999
  46. Published

    Biochemical evidence for heme linkage through esters with Asp93 and Glu214 in human eosinophil peroxidase. The ester with Asp93 is only partially formed in vivo. / Oxvig, C.; Thomsen, A.R.; Overgaard, M.T.; Sørensen, E.S.; Højrup, P.; Bjerrum, M.J.; Gleich, G.J.; Sottrup-Jensen, L.

    In: Journal of Biological Chemistry, Vol. 274, 1999, p. 16953-16958.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and proform of eosinophil major basic protein: Expression in reproductive and nonreproductive tissues. / Overgaard, M.T.; Oxvig, C.; Christiansen, M.; Gleich, G.J.; Sottrup-Jensen, L.; Haaning, J.

    In: Biol. Reprod., Vol. 61, 1999, p. 1083-1089.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. Published

    The crayfish plasma clotting protein: A vitellogenin-related protein responsible for clot formation in crustacean blood. / Hall, M.; Wang, R.; van Antwerpen, R.; Sottrup-Jensen, L.; Söderhäll, K.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, 1999, p. 1965-1970.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    The insulin-like growth factor (IGF)-dependent IFG binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. / Lawrence, J.B.; Oxvig, C.; Overgaard, M.T.; Sottrup-Jensen, L.; Gleich, G.J.; Hays, L.G.; Yates III, J.R.; Conover, C.A.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, 1999, p. 3149-3153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    The proform of eosinophil major basic protein: A new maternal serum marker for Down syndrome. / Christiansen, M.; Oxvig, C.; Wagner, J.M.; Qin, Q.-P.; Nguyen, T.H.; Larsen, S.O.; Sottrup-Jensen, L.; Gleich, G.J.; Nørgaard-Pedersen, B.

    In: Prenatal Diagnosis, Vol. 19, 1999, p. 905-910.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 1998
  52. Published

    Crystal structure of the receptor-binding domain of alpha 2-macroglobulin. / Jenner, L; Husted, L; Thirup, S; Sottrup-Jensen, L; Nyborg, J.

    In: Structure, Vol. 6, No. 5, 1998, p. 595-604.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Crystallization of human complement component C5. / Discipio, R G; Jenner, L; Thirup, S; Sottrup-Jensen, L; Nyborg, J; Stura, E.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 54, No. Pt 4, 1998, p. 643-6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. 1997
  55. Published

    Double-monoclonal immunofluorometric assays for pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/proMBP) complex in first-trimester maternal serum screening for Down syndrome. / Qin, Qui-Ping; Christiansen, Michael; Oxvig, Claus; Pettersson, Kim; Sottrup-Jensen, Lars; Koch, Claus; Nørgaard-Pedersen, Bent.

    In: Clinical Chemistry, Vol. 43, No. 12, 12.1997, p. 2323-2332.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Simple and reliable procedure for PCR amplification of genomic DNA from yeast cells using short sequencing primers. / Haaning, J; Oxvig, C; Overgaard, Michael Toft; Sottrup-Jensen, L.

    In: IUBMB Life, Vol. 42, No. 1, 1997, p. 169-72.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. 1996
  58. Published

    Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein. / Jacobsen, Linda; Madsen, Peder; Moestrup, Søren K; Lund, Anders Henrik; Tommerup, Niels; Nykjaer, A; Sottrup-Jensen, L; Gliemann, J; Petersen, C M.

    In: Journal of Biological Chemistry, Vol. 271, No. 49, 06.12.1996, p. 31379-31383.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Conformational changes of the reactive-centre loop and beta-strand 5A accompany temperature-dependent inhibitor-substrate transition of plasminogen-activator inhibitor 1. / Kjøller, L; Martensen, P M; Sottrup-Jensen, L; Justesen, J; Rodenburg, K W; Andreasen, P A.

    In: European Journal of Biochemistry, Vol. 241, No. 1, 01.10.1996, p. 38-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Molecular cloning of a novel human placental aminopeptidase. / Laustsen, P G; Rasmussen, T E; Petersen, K; Moestrup, S; Gliemann, J; Sottrup-Jensen, Lars; Kristensen, Torsten.

    1996. Abstract from 24th Meeting of the Federation of European Biochemical Societies, Barcelona, Spain.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  61. Published

    Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP. / Haaning, Jesper; Oxvig, Claus; Overgaard, Michael Toft; Ebbesen, Peter; Kristensen, Torsten; Sottrup-Jensen, Lars.

    In: European Journal of Biochemistry, Vol. 237, No. 1, 04.1996, p. 159-163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    Identification of residues in alpha-macroglobulins important for binding to the alpha2-macroglobulin receptor/Low density lipoprotein receptor-related protein. / Nielsen, Kåre L.; Holtet, Thor L.; Etzerodt, Michael; Moestrup, Søren Kragh; Gliemann, Jørgen; Sottrup-Jensen, Lars; Thøgersen, Hans Christian.

    In: Journal of Biological Chemistry, Vol. 271, No. 22, 1996, p. 12909-12912.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. 1995
  64. Published

    Low resolution X-ray structure of human methylamine-treated α2-macroglobulin. / Andersen, Gregers R.; Koch, Trine J.; Dolmer, Klavs; Sottrup-Jensen, Lars; Nyborg, Jens.

    In: Journal of Biological Chemistry, Vol. 270, No. 42, 20.10.1995, p. 25133-25141.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma. / Oxvig, Claus; Haaning, Jesper; Kristensen, Lene; Wagner, Jill M; Rubin, Inger; Stigbrand, Torgny; Gleich, Gerald J; Sottrup-Jensen, Lars.

    In: Journal of Biological Chemistry, Vol. 270, No. 23, 09.06.1995, p. 13645-13651.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    Crystallisation and preliminary X-ray analysis of the receptor-binding domain of human and bovine alpha 2-macroglobulin. / Dolmer, K; Jenner, Lasse Bohl; Jacobsen, L; Andersen, Gregers Rom; Koch, T J; Thirup, S; Sottrup-Jensen, L; Nyborg, J.

    In: F E B S Letters, Vol. 372, No. 1, 1995, p. 93-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    Expression and refolding of a high-affinity receptor binding domain from rat alpha(1)-Macroglobulin. / Nielsen, Kåre L; Sottrup-Jensen, Lars; Fey, G.H.; Thøgersen, Hans Christian.

    In: F E B S Letters, Vol. 373, No. 3, 1995, p. 296-298.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published
    Homo sapiens Pregnancy-associated plasma protein-A mRNA, complete cds. Genbank accession U28727. Haaning, J (Producer); Oxvig, Claus (Producer); Overgaard, M T (Producer); Ebbesen, P (Producer); Kristensen, Torsten (Producer); Sottrup-Jensen, Lars (Producer). 1995.

    Research output: Non-textual formDatasetResearch

  69. Published

    The cathodic hemoglobin of Anguilla anguilla. Amino acid sequence and oxygen equilibria of a reverse Bohr effect hemoglobin with high oxygen affinity and high phosphate sensitivity. / Fago, A; Carratore, V; di Prisco, G; Feuerlein, R J; Sottrup-Jensen, L; Weber, R E.

    In: Journal of Biological Chemistry, Vol. 270, No. 32, 1995, p. 18897-902.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. 1994
  71. Published

    Isolation and characterization of circulating complex between human pregnancy-associated plasma protein-A and proform of eosinophil major basic protein. / Oxvig, Claus; Sand, Ole; Kristensen, Torsten; Kristensen, Lene; Sottrup-Jensen, Lars.

    In: BBA General Subjects, Vol. 1201, No. 3, 15.12.1994, p. 415-423.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. Published

    Biochemical properties, activities, and presence in biologic fluids of eosinophil granule major basic protein. / Popken-Harris, Pamela; Thomas, Larry; Oxvig, Claus; Sottrup-Jensen, Lars; Kubo, Hirokazu; Klein, J S; Gleich, Gerald J.

    In: Journal of Allergy and Clinical Immunology, Vol. 94, No. 6 Pt 2, 12.1994, p. 1282-1289.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta. / Bonno, M; Oxvig, Claus; Kephart, G M; Wagner, J M; Kristensen, Torsten; Sottrup-Jensen, L; Gleich, G J.

    In: Laboratory Investigation, Vol. 71, No. 4, 10.1994, p. 560-566.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Structural integrity of the membrane domains in extensively trypsinized Na,K-ATPase from shark rectal glands. / Esmann, Mikael; Karlish, S J; Sottrup-Jensen, L; Marsh, D.

    In: Biochemistry, Vol. 33, No. 26, 05.07.1994, p. 8044-8050.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Location and nature of carbohydrate groups in proform of human major basic protein isolated from pregnancy serum. / Oxvig, Claus; Haaning, J; Højrup, Peter; Sottrup-Jensen, Lars.

    In: Biochemistry and Molecular Biology International, Vol. 33, No. 2, 05.1994, p. 329-336.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    Localization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic protein. / Oxvig, Claus; Gleich, G J; Sottrup-Jensen, Lars.

    In: FEBS Letters, Vol. 341, No. 2-3, 21.03.1994, p. 213-217.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA. / Kristensen, Torsten; Oxvig, Claus; Sand, Ole; Moeller, Niels Peter Hundahl; Sottrup-Jensen, Lars.

    In: Biochemistry, Vol. 33, No. 6, 15.02.1994, p. 1592-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Crystallization of human methylamine-treated complement C3 and C3b. / Dolmer, K.; Thirup, S.; Andersen, G. R.; Sottrup-Jensen, L.; Nyborg, J.

    In: Acta Crystallographica Section D: Biological Crystallography, Vol. 50, No. 5, 01.01.1994, p. 786-789.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    Low-resolution X-ray diffraction data obtained from hexagonal crystals of methylamine-treated alpha2-macroglobulin. / Andersen, G. R.; Thirup, S.; Nyborg, J.; Dolmer, Klaus; Jacobsen, Linda; Sottrup-Jensen, L.

    In: Acta Crystallographica Section D: Biological Crystallography, Vol. 50, No. 3, 01.01.1994, p. 298-301.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  80. Published

    Amino acid sequence of hen ovomacroglobulin (ovostatin) deduced from cloned cDNA. / Nielsen, Kåre L.; Sottrup-Jensen, Lars; Nagase, H.; Thøgersen, Hans Christian; Etzerodt, Michael.

    In: DNA Seq, Vol. 5, No. 2, 1994, p. 111-119.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    Crystallization of proteins of the alpha 2-macroglobulin superfamily. / Andersen, Gregers Rom; Koch, T; Sørensen, A H; Thirup, S; Nyborg, J; Dolmer, K; Jacobsen, L; Sottrup-Jensen, L.

    In: New York Academy of Sciences. Annals, Vol. 737, 1994, p. 444-6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  82. Published

    Receptor-binding domain of human alpha(2)-Macroglobulin. Expression, folding and biochemical characterization of a high-affinity recombinant derivative. / Holtet, Thor L.; Nielsen, Kåre L.; Etzerodt, Michael; Moestrup, Søren Kragh; Gliemann, Jørgen; Sottrup-Jensen, Lars; Thøgersen, Hans Christian.

    In: F E B S Letters, Vol. 344, No. 2-3, 1994, p. 242-246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes. / Andreasen, P A; Sottrup-Jensen, L; Kjøller, L; Nykjaer, A; Moestrup, S K; Petersen, C M; Gliemann, J.

    In: F E B S Letters, Vol. 338, No. 3, 1994, p. 239-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    Recombinant alpha(2)M receptor binding domain binds to the alpha(2)M receptor with high affinity. / Holtet, Thor L.; Nielsen, Kåre L.; Etzerodt, Michael; Moestrup, Søren Kragh; Gliemann, Jørgen; Sottrup-Jensen, Lars; Thøgersen, Hans Christian.

    In: Ann. N. Y. Acad. Sci., Vol. 737, 1994, p. 480-482.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  85. 1993
  86. Published

    Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein. / Oxvig, Claus; Sand, Ole; Kristensen, Torsten; Gleich, Gerald J; Sottrup-Jensen, Lars.

    In: Journal of Biological Chemistry, Vol. 268, No. 17, 15.06.1993, p. 12243-12246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha(2)-Macroglobulin receptor containing a cluster of eight complement-type repeats. / Moestrup, Søren Kragh; Holtet, Thor L.; Etzerodt, Michael; Thøgersen, Hans Christian; Nykjær, Anders; Andreasen, Peter; Rasmussen, H.H.; Sottrup-Jensen, Lars; Gliemann, Jørgen.

    In: Journal of Biological Chemistry, Vol. 268, No. 18, 1993, p. 13691-13696.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Assignment of the human gene for pregnancy-associated plasma protein A (PAPPA) to 9q33.1 by fluorescence in situ hybridization to mitotic and meiotic chromosomes. / Silahtaroglu , A N; Tümer, Z; Kristensen, Torsten; Sottrup-Jensen, Lars; Tommerum, N.

    In: Cytogenetics and Cell Genetics, Vol. 62, No. 4, 1993, p. 214-216.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. 1992
  90. Published
    Homo sapiens PAPP-A mRNA for pregnancy associated plasma protein-A. Genbank accession X68280. Sand, Ole (Producer); Kristensen, Torsten (Producer); Gleich, G J (Producer); Møller, N P (Producer); Sottrup-Jensen, Lars (Producer). 1992.

    Research output: Non-textual formDatasetResearch

  91. Published

    Occlusion of Rb+ after extensive tryptic digestion of shark rectal gland Na,K-ATPase. / Esmann, Mikael; Sottrup-Jensen, L.

    In: BBA General Subjects, Vol. 1108, No. 2, 27.07.1992, p. 247-252.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. Published

    Complete primary structure of bovine beta 2-glycoprotein I: localization of the disulfide bridges. / Bendixen, Emøke; Halkier, Torben; Magnusson, Staffan; Sottrup-Jensen, Lars; Kristensen, Torsten.

    In: Biochemistry, Vol. 31, No. 14, 14.04.1992, p. 3611-3617.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  93. 1991
  94. Published

    Molecular cloning and mammalian expression of human beta 2-glycoprotein I cDNA. / Kristensen, Torsten; Schousboe, Inger; Boel, Espen; Mulvihill , Eileen M; Hansen, Rita Rosendahl; Møller, Karin Bach; Møller, Niels Peter Hundahl; Sottrup-Jensen, Lars.

    In: FEBS Letters, Vol. 289, No. 2, 09.09.1991, p. 183-186.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    Pregnancy-Associated Plasma Protein A Belongs to the Factor H Superfamily. / Kristensen, Torsten; Sand, O; Folkersen, J; Møller, N P H; Sottrup-Jensen, Lars.

    In: Complement and Inflammation, Vol. 8, No. 3-4, 09.1991, p. 178-178.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  96. Published

    Evidence that the alpha-2-macroglobulin receptor is identical with the newly cloned Low-Density-Lipoprotein-Receptor Related Protein (LRP). / Kristensen, Torsten; Bendtsen, L; Moestrup, S K; Gliemann, J; Sand, O ; Sottrup-Jensen, Lars.

    In: Biological chemistry Hoppe-Seyler, Vol. 372, 03.1991, p. 140-141.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  97. Published

    Expression of wild type human alpha-2-macroglobulin and a bait region mutant in Baby Hamster Kidney fibroblasts. Biol. Chem. Hoppe-Seyler 372, p132. / Boel, E; Kristensen, Torsten; Petersen, C M; Mortensen, S B; Gliemann, J; Møller, N P H; Sottrup-Jensen, Lars.

    In: Biological chemistry Hoppe-Seyler, Vol. 372, 03.1991, p. 132.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  98. Published

    Crystallization and preliminary X-ray analysis of methylamine-treated alpha 2-macroglobulin and 3 alpha 2-macroglobulin-proteinase complexes. / Andersen, Gregers Rom; Jacobsen, L; Thirup, S; Nyborg, J; Sottrup-Jensen, L.

    In: F E B S Letters, Vol. 292, No. 1-2, 1991, p. 267-70.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. 1990
  100. Published

    Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the alpha 2-macroglobulin receptor. / Kristensen, Torsten; Moestrup, Søren Kragh; Gliemann, Jørgen; Bendtsen, Lone; Sand, Ole; Sottrup-Jensen, Lars.

    In: FEBS Letters, Vol. 276, No. 1-2, 10.12.1990, p. 151-155.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published
    Homo sapiens mRNA fragment for alpha-2 macroglobulin receptor. Genbank accession X55077. Kristensen, Torsten (Producer); Moestrup, S K (Producer); Gliemann, Jørgen (Producer); Bendtsen, L (Producer); Sand, O (Producer); Sottrup-Jensen, Lars (Producer). 1990.

    Research output: Non-textual formDatasetResearch

  102. Published
    Homo sapiens mRNA for beta-2-glycoprotein I (apolipoprotein H). Complete cds. Genbank accession X53595. Kristensen, Torsten (Producer); Schousboe, I (Producer); Boel, E (Producer); Mulvihill, E M (Producer); Hansen, R R (Producer); Møller, K B (Producer); Møller, N P (Producer); Sottrup-Jensen, Lars (Producer). 1990.

    Research output: Non-textual formDatasetResearch

  103. Published

    Expression of human alpha 2-macroglobulin cDNA in baby hamster kidney fibroblasts: secretion of high levels of active alpha 2-macroglobulin. / Boel, Esper; Kristensen, Torsten; Petersen, Claus Munck; Mortensen, Steen B; Gliemann, Jørgen; Sottrup-Jensen, Lars.

    In: Biochemistry, Vol. 29, No. 17, 05.1990, p. 4081-4007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. 1989
  105. Published

    Immunosuppressive properties of electrophoretically "slow" and "fast" form alpha 2-macroglobulin. Effects on cell-mediated cytotoxicity and (allo-) antigen-induced T cell proliferation. / Petersen, C M; Ejlersen, E; Moestrup, S K; Jensen, Poul Henning; Sand, O; Sottrup-Jensen, L.

    In: Journal of Immunology, Vol. 142, No. 2, 15.01.1989, p. 629-635.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. 1988
  107. Published

    Receptors for a2-Macroglobulin- and pregnancy zone protein-proteinase complexes in the human placental syncytiotrophoblast. / Jensen, Poul Henning; Moestrup, S K; Sottrup-Jensen, Lars; Petersen, Claus Munch; Gliemann, Jørgen.

    In: Placenta, Vol. 9, No. 5, 09.1988, p. 463-477.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. Published

    Human hepatocytes exhibit receptors for alpha 2-macroglobulin and pregnancy zone protein-proteinase complexes. / Petersen, C M; Christiansen, B S; Jensen, Poul Henning; Moestrup, S K; Gliemann, J; Sottrup-Jensen, L; Ingerslev, J.

    In: European Journal of Clinical Investigation, Vol. 18, No. 2, 1988, p. 184-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. 1987
  110. Published

    Binding and receptor-mediated endocytosis of pregnancy zone protein-proteinase complex in rat macrophages. / Moestrup, S K; Christensen, Erik Ilsø; Sottrup-Jensen, L; Gliemann, J.

    In: BBA General Subjects, Vol. 930, No. 3, 1987, p. 297-303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  111. 1986
  112. Published

    Evidence for binding of human pregnancy zone protein-proteinase complex to a2-Macroglobulin receptors. / Gliemann, Jørgen; Moestrup, Søren Kragh; Jensen, Poul Henning; Sottrup-Jensen, L; Andersen, Hanne Busk; Petersen, Claus Munck; Sonne, Ole; Madsen, Peder.

    In: BBA General Subjects, Vol. 883, No. 3, 01.10.1986, p. 400-406.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  113. 1985
  114. Published

    Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. / Sottrup-Jensen, Lars; Stepanik, T M; Kristensen, Torsten; Lønblad, P B; Jones, C M; Wierzbicki, D M ; Magnusson, S; Domdey, H; Wetzel, R A; Lundwall, A.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 82, No. 1, 01.1985, p. 9-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  115. 1984
  116. Published

    Partial primary structure of human pregnancy zone protein: extensive sequence homology with human alpha 2-macroglobulin. / Sottrup-Jensen, Lars; Folkersen, J; Kristensen, Torsten; Tack, B F.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 81, No. 23, 12.1984, p. 7353-7357.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  117. Published

    Primary structure of human alpha 2-macroglobulin. I. Isolation of the 26 CNBr fragments, amino acid sequence of 13 small CNBr fragments, amino acid sequence of methionine-containing peptides, and alignment of all CNBr fragments. / Sottrup-Jensen, Lars; Stepanik, T M; Jones, C M; Lønblad, P B; Kristensen, Torsten; Wierzbicki, DM.

    In: Journal of Biological Chemistry, Vol. 259, No. 13, 10.07.1984, p. 8293-8303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  118. Published

    Primary structure of human alpha 2-macroglobulin. IV. Primary structure of two large CNBr fragments, located in the COOH-terminal part and accounting for 337 residues. / Kristensen, Torsten; Wierzbicki, D M; Sottrup-Jensen, Lars.

    In: Journal of Biological Chemistry, Vol. 259, No. 13, 10.07.1984, p. 8313-8317.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  119. Published

    Primary structure of human alpha 2-macroglobulin. V. The complete structure. / Sottrup-Jensen, Lars; Stepanik, Terrence M; Kristensen, Torsten; Wierzbicke, Diane M; Jones, Claire M; Lønblad, Peter B; Magnusson, Staffan; Petersen, Torben Ellebæk.

    In: Journal of Biological Chemistry, Vol. 259, No. 13, 07.1984, p. 8318-8327.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  120. 1983
  121. Published

    The primary structure of alpha2-macroglobulin and localization of a Factor XIIIa cross-linking sitea. / Sottrup-Jensen, Lars; Stepanik, Terrence M; Wierzbicki, Diane M; Jones, Claire M; Lønblad, Peter B; Kristensen, Torsten; Mortensen, Steen B; Petersen, Torben Ellebæk; Magnusson, Staffan.

    In: Annals of The New York Academy of Science, Vol. 421, 12.1983, p. 41-60.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  122. Published

    Partial primary structure of bovine plasma fibronectin: three types of internal homology. / Petersen, Torben Ellebæk; Thøgersen, Hans Christian; Skorstengaard, Karna; Vibe-Pedersen, Karen; Sahl, Preben; Sottrup-Jensen, Lars; Magnusson, Staffan.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 80, No. 1, 1983, p. 137-141.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  123. 1981
  124. Published

    Amino acid sequence of the factor XIIIa acceptor-site in bovine plasma fibronectin. / McDonagh, R. P.; McDonagh, Jan; Petersen, Torben Ellebæk; Thøgersen, Hans Christian; Skorstengaard, Karna; Sottrup-Jensen, Lars; Magnusson, Staffan; Dell, Anne; Morris, Howard R.

    In: F E B S Letters, Vol. 127, No. 2, 1981, p. 174-178.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  125. 1980
  126. Published

    Isolation and N-terminal amino acid sequence of Protein-Z, a gamma-carboxyglutamic acid containing protein from bovine plasma. / Petersen, Torben Ellebæk; Thøgersen, Hans Christian; Sottrup-Jensen, Lars; Magnusson, Staffan; Jörnvall, Hans.

    In: F E B S Letters, Vol. 114, No. 2, 1980, p. 278-282.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  127. 1978
  128. Published

    The N-terminal sequences of blood coagulation factor X1 and X2 light chains. Mass-spectrometric identification of twelve residues of gamma-carboxyglutamic acid in their vitamin K-dependent domains. / Thøgersen, Hans Christian; Petersen, Torben Ellebæk; Sottrup-Jensen, Lars; Magnusson, Staffan; Morris, Howard R.

    In: Biochem. J., Vol. 175, No. 2, 1978, p. 613-627.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review