Lars Jørgen Østergaard

Home screening for sexually transmitted diseases in high-risk young women: randomised controlled trial.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Robert L Cook, Denmark
  • Lars Østergaard
  • Sharon L Hillier, Denmark
  • Pamela J Murray, Denmark
  • Chung-Chou H Chang, Denmark
  • Diane M Comer, Denmark
  • Roberta B Ness, Denmark
  • DAISY study team
  • The Department of Infectious Diseases
OBJECTIVE: Home screening tests could eliminate several barriers to testing sexually transmitted diseases (STDs). AIM: To determine whether offering repeated home screening tests would increase the rate of testing for chlamydia and gonorrhoea in a high-risk sample of young women. METHODS: In this randomised controlled trial, 403 young women (mean age 18.9 years, 70% black) with a recent STD or with STD-related risk factors were enrolled. Participants were recruited from clinics and high-prevalence neighbourhoods and then randomly assigned to receive either a home testing kit or an invitation to attend a medical clinic for testing at 6, 12 and 18 months after enrollment. Over 80% of women were followed for 2 years. The trial is registered with, number NCT 00177437. RESULTS: Of 197 women in the intervention group, 140 (71%) returned at least one home test and 25 of 249 (10%) home tests were positive. Women who received home screening tests completed significantly more STD tests overall (1.94 vs 1.41 tests per woman-year, p<0.001) and more STD tests in the absence of symptoms (1.18 vs 0.75 tests per woman-year, p<0.001). More women in the intervention group completed at least one test when asymptomatic (162 (82.2%) vs 117 (61.3%), p<0.001). The intervention was most effective among women recruited outside medical clinics. There was no significant difference in the overall rate of STDs detected. CONCLUSIONS: Home screening significantly increased the utilisation of chlamydia and gonorrhoea testing in this sample of high-risk young women, and thus represents a feasible strategy to facilitate STD testing in young women.
Udgivelsesdato: 2007-Jul
Original languageEnglish
JournalSexually Transmitted Infections
Pages (from-to)286-91
Number of pages5
Publication statusPublished - 2007

    Research areas

  • Adolescent, Adult, Chlamydia Infections, Chlamydia trachomatis, Female, Gonorrhea, Home Care Services, Humans, Mass Screening, Patient Acceptance of Health Care, Risk Factors, Sensitivity and Specificity

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