Lars Henrik Fugger

  1. 2020
  2. Published

    Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient. / Attfield, Kate; Iversen, Astrid Kn; Gold, Ralf; Fugger, Lars; Haghikia, Aiden.

    In: Multiple sclerosis (Houndmills, Basingstoke, England), Vol. 26, No. 10, 09.2020, p. 1261-1264.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Inflammation-related plasma and CSF biomarkers for multiple sclerosis. / Huang, Jesse; Khademi, Mohsen; Fugger, Lars; Lindhe, Örjan; Novakova, Lenka; Axelsson, Markus; Malmeström, Clas; Constantinescu, Clara; Lycke, Jan; Piehl, Fredrik; Olsson, Tomas; Kockum, Ingrid.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 23, 09.06.2020, p. 12952-12960.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    A novel neurodegenerative spectrum disorder in patients with MLKL deficiency. / Faergeman, Soren L.; Evans, Hayley; Attfield, Kathrine E.; Desel, Christiane; Kuttikkatte, Subita Balaram; Sommerlund, Mette; Jensen, Lise Torp; Frokiaer, Jorgen; Friese, Manuel A.; Matthews, Paul M.; Luchtenborg, Christian; Brügger, Britta; Oturai, Annette Bang; Dendrou, Calliope A.; Fugger, Lars.

    In: Cell Death and Disease, Vol. 11, 303, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases. / Fugger, Lars; Jensen, Lise Torp; Rossjohn, Jamie.

    In: Cell, Vol. 181, No. 1, 04.2020, p. 63-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  6. Published

    B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2. / du Pré, M Fleur; Blazevski, Jana; Dewan, Alisa E; Stamnaes, Jorunn; Kanduri, Chakravarthi; Sandve, Geir Kjetil; Johannesen, Marie K; Lindstad, Christian B; Hnida, Kathrin; Fugger, Lars; Melino, Gerry; Qiao, Shuo-Wang; Sollid, Ludvig M.

    In: The Journal of Experimental Medicine, Vol. 217, No. 2, e20190860, 03.02.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Identifying cross-disease components of genetic risk across hospital data in the UK Biobank. / Cortes, Adrian; Albers, Patrick K; Dendrou, Calliope A; Fugger, Lars; McVean, Gil.

    In: Nature Genetics, Vol. 52, No. 1, 01.2020, p. 126-134.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2019
  9. Published

    A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity. / Ooi, Joshua D; Jiang, Jhih-Hang; Eggenhuizen, Peter J; Chua, Ling L; van Timmeren, Mirjan; Loh, Khai L; O'Sullivan, Kim M; Gan, Poh Y; Zhong, Yong; Tsyganov, Kirill; Shochet, Lani R; Ryan, Jessica; Stegeman, Coen A; Fugger, Lars; Reid, Hugh H; Rossjohn, Jamie; Heeringa, Peter; Holdsworth, Stephen R; Peleg, Anton Y; Kitching, A Richard.

    In: Nature Communications, Vol. 10, No. 1, 3392, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2018
  11. Published

    HLA variation and disease. / Dendrou, Calliope A; Petersen, Jan; Rossjohn, Jamie; Fugger, Lars.

    In: Nature Reviews. Immunology, Vol. 18, No. 5, 05.2018, p. 325-339.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  12. 2017
  13. Published

    Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank. / Cortes, Adrian; Dendrou, Calliope A; Motyer, Allan; Jostins, Luke; Vukcevic, Damjan; Dilthey, Alexander; Donnelly, Peter; Leslie, Stephen; Fugger, Lars; McVean, Gil.

    In: Nature Genetics, Vol. 49, No. 9, 09.2017, p. 1311-1318.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Structural and regulatory diversity shape HLA-C protein expression levels. / Kaur, Gurman; Gras, Stephanie; Mobbs, Jesse I; Vivian, Julian P; Cortes, Adrian; Barber, Thomas; Kuttikkatte, Subita Balaram; Jensen, Lise Torp; Attfield, Kathrine E; Dendrou, Calliope A; Carrington, Mary; McVean, Gil; Purcell, Anthony W; Rossjohn, Jamie; Fugger, Lars.

    In: Nature Communications, Vol. 8, 26.06.2017, p. 15924.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. / Ooi, Joshua D; Petersen, Jan; Tan, Yu H; Huynh, Megan; Willett, Zoe J; Ramarathinam, Sri H; Eggenhuizen, Peter J; Loh, Khai L; Watson, Katherine A; Gan, Poh Y; Alikhan, Maliha A; Dudek, Nadine L; Handel, Andreas; Hudson, Billy G; Fugger, Lars; Power, David A; Holt, Stephen G; Coates, P Toby; Gregersen, Jon W; Purcell, Anthony W; Holdsworth, Stephen R; La Gruta, Nicole L; Reid, Hugh H; Rossjohn, Jamie; Kitching, A Richard.

    In: Nature, Vol. 545, No. 7653, 11.05.2017, p. 243-247.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Severe B-cell-mediated CNS disease secondary to alemtuzumab therapy. / Haghikia, Aiden; Dendrou, Calliope A; Schneider, Ruth; Grüter, Thomas; Postert, Thomas; Matzke, Mike; Stephanik, Heike; Fugger, Lars; Gold, Ralf.

    In: Lancet Neurology, Vol. 16, No. 2, 02.2017, p. 104-106.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Immunomodulation in multiple sclerosis : promises and pitfalls. / Dendrou, Calliope A; Fugger, Lars.

    In: Current Opinion in Immunology, Vol. 49, 2017, p. 37-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  18. 2016
  19. Published

    Neuroinflammation - using big data to inform clinical practice. / Dendrou, Calliope A; McVean, Gil; Fugger, Lars.

    In: Nature Reviews. Neurology, Vol. 12, No. 12, 12.2016, p. 685-698.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. / Dendrou, Calliope A; Cortes, Adrian; Shipman, Lydia; Evans, Hayley G; Attfield, Kathrine E; Jostins, Luke; Barber, Thomas; Kaur, Gurman; Kuttikkatte, Subita Balaram; Leach, Oliver A; Desel, Christiane; Faergeman, Soren L; Cheeseman, Jane; Neville, Matt J; Sawcer, Stephen; Compston, Alastair; Johnson, Adam R; Everett, Christine; Bell, John I; Karpe, Fredrik; Ultsch, Mark; Eigenbrot, Charles; McVean, Gil; Fugger, Lars.

    In: Science Translational Medicine, Vol. 8, No. 363, 02.11.2016, p. 363ra149.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination. / Grodeland, Gunnveig; Fredriksen, Agnete Brunsvik; Løset, Geir Åge; Vikse, Elisabeth; Fugger, Lars; Bogen, Bjarne.

    In: Journal of Immunology, Vol. 197, No. 9, 01.11.2016, p. 3575-3585.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Inhibitory Interplay between Orexin Neurons and Eating. / González, J Antonio; Jensen, Lise T; Iordanidou, Panagiota; Strom, Molly; Fugger, Lars; Burdakov, Denis.

    In: Current Biology, Vol. 26, No. 18, 26.09.2016, p. 2486-91.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions. / Jönsson, Peter; Southcombe, Jennifer H; Santos, Ana Mafalda; Huo, Jiandong; Fernandes, Ricardo A; McColl, James; Lever, Melissa; Evans, Edward J; Hudson, Alexander; Chang, Veronica T; Hanke, Tomáš; Godkin, Andrew; Dunne, Paul D; Horrocks, Mathew H; Palayret, Matthieu; Screaton, Gavin R; Petersen, Jan; Rossjohn, Jamie; Fugger, Lars; Dushek, Omer; Xu, Xiao-Ning; Davis, Simon J; Klenerman, David.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 20, 17.05.2016, p. 5682-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2015
  25. Published

    Immunopathology of multiple sclerosis. / Dendrou, Calliope A; Fugger, Lars; Friese, Manuel A.

    In: Nature Reviews. Immunology, Vol. 15, No. 9, 15.09.2015, p. 545-58.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. / Taylor, Jenny C; Martin, Hilary C; Lise, Stefano; Broxholme, John; Cazier, Jean-Baptiste; Rimmer, Andy; Kanapin, Alexander; Lunter, Gerton; Fiddy, Simon; Allan, Chris; Aricescu, A Radu; Attar, Moustafa; Babbs, Christian; Becq, Jennifer; Beeson, David; Bento, Celeste; Bignell, Patricia; Blair, Edward; Buckle, Veronica J; Bull, Katherine; Cais, Ondrej; Cario, Holger; Chapel, Helen; Copley, Richard R; Cornall, Richard; Craft, Jude; Dahan, Karin; Davenport, Emma E; Dendrou, Calliope; Devuyst, Olivier; Fenwick, Aimée L; Flint, Jonathan; Fugger, Lars; Gilbert, Rodney D; Goriely, Anne; Green, Angie; Greger, Ingo H; Grocock, Russell; Gruszczyk, Anja V; Hastings, Robert; Hatton, Edouard; Higgs, Doug; Hill, Adrian; Holmes, Chris; Howard, Malcolm; Hughes, Linda; Humburg, Peter; Johnson, David; Karpe, Fredrik; Kingsbury, Zoya; Kini, Usha; Knight, Julian C; Krohn, Jonathan; Lamble, Sarah; Langman, Craig; Lonie, Lorne; Luck, Joshua; McCarthy, Davis; McGowan, Simon J; McMullin, Mary Frances; Miller, Kerry A; Murray, Lisa; Németh, Andrea H; Nesbit, M Andrew; Nutt, David; Ormondroyd, Elizabeth; Oturai, Annette Bang; Pagnamenta, Alistair; Patel, Smita Y; Percy, Melanie; Petousi, Nayia; Piazza, Paolo; Piret, Sian E; Polanco-Echeverry, Guadalupe; Popitsch, Niko; Powrie, Fiona; Pugh, Chris; Quek, Lynn; Robbins, Peter A; Robson, Kathryn; Russo, Alexandra; Sahgal, Natasha; van Schouwenburg, Pauline A; Schuh, Anna; Silverman, Earl; Simmons, Alison; Sørensen, Per Soelberg; Sweeney, Elizabeth; Taylor, John; Thakker, Rajesh V; Tomlinson, Ian; Trebes, Amy; Twigg, Stephen R F; Uhlig, Holm H; Vyas, Paresh; Vyse, Tim; Wall, Steven A; Watkins, Hugh; Whyte, Michael P; Witty, Lorna; Wright, Ben; Yau, Chris; Buck, David; Humphray, Sean; Ratcliffe, Peter J; Bell, John I; Wilkie, Andrew O M; Bentley, David; Donnelly, Peter; McVean, Gilean.

    In: Nature Genetics, Vol. 47, No. 7, 07.2015, p. 717-26.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Amiloride Clinical Trial In Optic Neuritis (ACTION) protocol : a randomised, double blind, placebo controlled trial. / McKee, Justin B; Elston, John; Evangelou, Nikos; Gerry, Stephen; Fugger, Lars; Kennard, Christopher; Kong, Yazhuo; Palace, Jacqueline; Craner, Matthew.

    In: BMJ Open, Vol. 5, No. 11, 2015, p. e009200.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2014
  29. Published

    Please mind the gap : axonal transport deficits in multiple sclerosis neurodegeneration. / Dendrou, Calliope A; Fugger, Lars.

    In: Neuron, Vol. 84, No. 6, 17.12.2014, p. 1105-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. / Tenzer, Stefan; Crawford, Hayley; Pymm, Phillip; Gifford, Robert; Sreenu, Vattipally B; Weimershaus, Mirjana; de Oliveira, Tulio; Burgevin, Anne; Gerstoft, Jan; Akkad, Nadja; Lunn, Daniel; Fugger, Lars; Bell, John; Schild, Hansjörg; van Endert, Peter; Iversen, Astrid K N.

    In: Cell Reports, Vol. 7, No. 2, 24.04.2014, p. 448-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Multiple sclerosis : Insights into pathophysiology and novel therapeutic avenues. / Gold, Ralf; Fugger, Lars.

    In: Experimental Neurology, 18.04.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis. / Friese, Manuel A; Schattling, Benjamin; Fugger, Lars.

    In: Nature Reviews. Neurology, Vol. 10, No. 4, 04.2014, p. 225-38.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. 2013
  34. Published

    A clinical conundrum : the detrimental effect of TNF antagonists in multiple sclerosis. / Dendrou, Calliope A; Bell, John I; Fugger, Lars.

    In: Pharmacogenomics, Vol. 14, No. 12, 09.2013, p. 1397-404.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Therapies for multiple sclerosis : translational achievements and outstanding needs. / Haghikia, Aiden; Hohlfeld, Reinhard; Gold, Ralf; Fugger, Lars.

    In: Trends in Molecular Medicine, Vol. 19, No. 5, 05.2013, p. 309-19.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    TCR transgenic mice that shed light on immune and environmental regulators in multiple sclerosis. / Attfield, Kathrine E; Fugger, Lars.

    In: Journal of Immunology, Vol. 190, No. 7, 01.04.2013, p. 3015-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. / Ooi, Joshua D; Chang, Janet; O'Sullivan, Kim M; Pedchenko, Vadim; Hudson, Billy G; Vandenbark, Arthur A; Fugger, Lars; Holdsworth, Stephen R; Kitching, A Richard.

    In: Journal of the American Society of Nephrology, Vol. 24, No. 3, 02.2013, p. 419-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Weighing in on autoimmune disease : Big data tip the scale. / Dendrou, Calliope A; Bell, John I; Fugger, Lars.

    In: Nature Medicine, Vol. 19, No. 2, 02.2013, p. 138-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Targeting ASIC1 in primary progressive multiple sclerosis : evidence of neuroprotection with amiloride. / Arun, Tarunya; Tomassini, Valentina; Sbardella, Emilia; de Ruiter, Michiel B; Matthews, Lucy; Leite, Maria Isabel; Gelineau-Morel, Rose; Cavey, Ana; Vergo, Sandra; Craner, Matt; Fugger, Lars; Rovira, Alex; Jenkinson, Mark; Palace, Jacqueline.

    In: Brain, Vol. 136, No. Pt 1, 01.2013, p. 106-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. 2012
  41. Published

    Genomewide association studies and common disease--realizing clinical utility. / Fugger, Lars; McVean, Gil; Bell, John I.

    In: Briefings from the New England Journal of Medicine (Spanish Edition), Vol. 367, No. 25, 20.12.2012, p. 2370-1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon. / Armitage, Andrew E; Deforche, Koen; Chang, Chih-Hao; Wee, Edmund; Kramer, Beatrice; Welch, John J; Gerstoft, Jan; Fugger, Lars; McMichael, Andrew; Rambaut, Andrew; Iversen, Astrid K N.

    In: PLoS genetics, Vol. 8, No. 3, 2012, p. e1002550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Autoimmunity's next top models. / Wekerle, Hartmut; Flügel, Alexander; Fugger, Lars; Schett, Georg; Serreze, David.

    In: Nature Medicine, Vol. 18, No. 1, 2012, p. 66-70.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Bridging the gap from genetic association to functional understanding : the next generation of mouse models of multiple sclerosis. / Attfield, Kathrine E; Dendrou, Calliope A; Fugger, Lars.

    In: Immunological Reviews, Vol. 248, No. 1, 2012, p. 10-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Convergent inputs from electrically and topographically distinct orexin cells to locus coeruleus and ventral tegmental area. / González, J Antonio; Jensen, Lise T; Fugger, Lars; Burdakov, Denis.

    In: The European journal of neuroscience, Vol. 35, No. 9, 2012, p. 1426-32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Misfiring in multiple sclerosis : Cerebellar Channelopathy, a Potential Novel Target? / Craner, Matt J; Fugger, Lars.

    In: Annals of Neurology, Vol. 71, No. 4, 2012, p. 437-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Natural killer cells and their receptors in multiple sclerosis. / Kaur, Gurman; Trowsdale, John; Fugger, Lars.

    In: Brain, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. Published

    TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. / Gregory, Adam P; Dendrou, Calliope A; Attfield, Kathrine E; Haghikia, Aiden; Xifara, Dionysia K; Butter, Falk; Poschmann, Gereon; Kaur, Gurman; Lambert, Lydia; Leach, Oliver A; Prömel, Simone; Punwani, Divya; Felce, James H; Davis, Simon J; Gold, Ralf; Nielsen, Finn C; Siegel, Richard M; Mann, Matthias; Bell, John I; McVean, Gil; Fugger, Lars.

    In: Nature, Vol. 488, No. 7412, 2012, p. 508-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. / Ooi, Joshua D; Chang, Janet; Hickey, Michael J; Borza, Dorin-Bogdan; Fugger, Lars; Holdsworth, Stephen R; Kitching, A Richard.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 109, No. 39, 2012, p. E2615-24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Use of calcium channel blockers and Parkinson's disease. / Pasternak, Björn; Svanström, Henrik; Nielsen, Nete M; Fugger, Lars; Melbye, Mads; Hviid, Anders.

    In: American Journal of Epidemiology, Vol. 175, No. 7, 2012, p. 627-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 2011
  52. Published

    Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells. / Du Pré, M Fleur; Kozijn, Anne E; van Berkel, Lisette A; ter Borg, Mariëtte N D; Lindenbergh-Kortleve, Dicky; Jensen, Lise Torp; Kooy-Winkelaar, Yvonne; Koning, Frits; Boon, Louis; Nieuwenhuis, Edward E S; Sollid, Ludvig M; Fugger, Lars; Samsom, Janneke N.

    In: Gastroenterology, Vol. 141, No. 2, 01.08.2011, p. 610-620.e2.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG. / Rigaud, Stéphanie; Lopez-Granados, Eduardo; Sibéril, Sophie; Gloire, Geoffrey; Lambert, Nathalie; Lenoir, Christelle; Synaeve, Cindy; Stacey, Maria; Fugger, Lars; Stephan, Jean-Louis; Fischer, Alain; Picard, Capucine; Durandy, Anne; Chapel, Helen; Latour, Sylvain.

    In: Ironic Blood, Vol. 118, No. 2, 14.07.2011, p. 252-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis. / McMahon, Róisín M; Friis, Lone Smidstrup; Siebold, Christian; Friese, Manuel A; Fugger, Lars; Jones, E Yvonne.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 67, No. Pt 5, 01.05.2011, p. 447-54.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Axonal injury in reverse. / Craner, Matt J; Fugger, Lars.

    In: Nature Medicine, Vol. 17, No. 4, 01.04.2011, p. 423-6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model. / Vergo, Sandra; Craner, Matthew J; Etzensperger, Ruth; Attfield, Kathrine; Friese, Manuel A; Newcombe, Jia; Esiri, Margaret; Fugger, Lars.

    In: Brain, Vol. 134, No. Pt 2, 01.02.2011, p. 571-84.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Direct and indirect control of orexin/hypocretin neurons by glycine receptors. / Karnani, Mahesh M; Venner, Anne; Jensen, Lise T; Fugger, Lars; Burdakov, Denis.

    In: Journal of Physiology, Vol. 589, No. 3, 01.02.2011, p. 639-651.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain. / Tzartos, John S; Craner, Matthew J; Friese, Manuel A; Jakobsen, Karen Bryde; Newcombe, Jia; Esiri, Margaret M; Fugger, Lars.

    In: American Journal of Pathology, Vol. 178, No. 2, 01.02.2011, p. 794-802.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Activation of central orexin/hypocretin neurons by dietary amino acids. / Karnani, Mahesh M; Apergis-Schoute, John; Adamantidis, Antoine; Jensen, Lise T; de Lecea, Luis; Fugger, Lars; Burdakov, Denis.

    In: Sensory Neuron, Vol. 72, No. 4, 2011, p. 616-29.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels. / Venner, Anne; Karnani, Mahesh M; Gonzalez, J Antonio; Jensen, Lise T; Fugger, Lars; Burdakov, Denis.

    In: Journal of Physiology, Vol. 589, No. Pt 23, 2011, p. 5701-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. 2010
  62. Published

    An alternative conformation of the T-cell receptor beta constant region. / van Boxel, Gijs I; Holmes, Samantha; Fugger, Lars; Jones, E Yvonne.

    In: Journal of Molecular Biology, Vol. 400, No. 4, 2010, p. 828-37.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. / Nika, Konstantina; Soldani, Cristiana; Salek, Mogjiborahman; Paster, Wolfgang; Gray, Adrian; Etzensperger, Ruth; Fugger, Lars; Polzella, Paolo; Cerundolo, Vincenzo; Dushek, Omer; Höfer, Thomas; Viola, Antonella; Acuto, Oreste.

    In: Immunity, Vol. 32, No. 6, 2010, p. 766-77.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. 2009
  65. Published

    Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. / Tenzer, Stefan; Wee, Edmund; Burgevin, Anne; Stewart-Jones, Guillaume; Friis, Lone; Lamberth, Kasper; Chang, Chih-Hao; Harndahl, Mikkel; Weimershaus, Mirjana; Gerstoft, Jan; Akkad, Nadja; Klenerman, Paul; Fugger, Lars; Jones, E Yvonne; McMichael, Andrew J; Buus, Søren; Schild, Hansjörg; van Endert, Peter; Iversen, Astrid K N.

    In: Nature Immunology, Vol. 10, No. 6, 2009, p. 636-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons. / González, J A; Jensen, Lise T; Doyle, Susan E; Miranda-Anaya, Manuel; Menaker, Michael; Fugger, Lars; Bayliss, Douglas A; Burdakov, Denis.

    In: European Journal of Neuroscience, Vol. 30, No. 1, 2009, p. 57-64.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    From genes to function: the next challenge to understanding multiple sclerosis. / Fugger, Lars; Friese, Manuel A; Bell, John I.

    In: Nature Reviews. Immunology, Vol. 9, No. 6, 2009, p. 408-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. / Call, Melissa J; Xing, Xuechao; Cuny, Gregory D; Seth, Nilufer P; Altmann, Daniel M; Fugger, Lars; Krogsgaard, Michelle; Stein, Ross L; Wucherpfennig, Kai W.

    In: Journal of Immunology, Vol. 182, No. 10, 2009, p. 6342-52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Pathogenic CD8(+) T cells in multiple sclerosis. / Friese, Manuel A; Fugger, Lars.

    In: Annals of Neurology, Vol. 66, No. 2, 2009, p. 132-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Stimulation of orexin/hypocretin neurones by thyrotropin-releasing hormone. / González, J Antonio; Horjales-Araujo, Emilia; Fugger, Lars; Broberger, Christian; Burdakov, Denis.

    In: Journal of Physiology, Vol. 587, No. Pt 6, 2009, p. 1179-86.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  71. Published

    T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. / Harkiolaki, Maria; Holmes, Samantha L; Svendsen, Pia; Gregersen, Jon W; Jensen, Lise T; McMahon, Roisin; Friese, Manuel A; van Boxel, Gijs; Etzensperger, Ruth; Tzartos, John S; Kranc, Kamil; Sainsbury, Sarah; Harlos, Karl; Mellins, Elizabeth D; Palace, Jackie; Esiri, Margaret M; van der Merwe, P Anton; Jones, E Yvonne; Fugger, Lars.

    In: Immunity, Vol. 30, No. 3, 2009, p. 348-57.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. 2008
  73. Published

    Adaptive sugar sensors in hypothalamic feeding circuits. / Williams, Rhiannan H; Alexopoulos, Haris; Jensen, Lise T; Fugger, Lars; Burdakov, Denis.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 33, 2008, p. 11975-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Dissection of the multiple sclerosis associated DR2 haplotype. / Etzensperger, Ruth; McMahon, Róisín M; Jones, E Yvonne; Fugger, Lars.

    In: Journal of Autoimmunity, Vol. 31, No. 3, 2008, p. 201-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. / Tzartos, JS; Friese, MA; Craner, MJ; Palace, J; Newcombe, J; Esiri, MM; Fugger, Lars Henrik.

    In: American Journal of Pathology, Vol. 172, No. 1, 2008, p. 146-155.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  76. Published

    Metabolism-independent sugar sensing in central orexin neurons. / González, J Antonio; Jensen, Lise T; Fugger, Lars; Burdakov, Denis.

    In: Diabetes, Vol. 57, No. 10, 2008, p. 2569-76.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. / Friese, Manuel A; Jakobsen, Karen B; Friis, Lone; Etzensperger, Ruth; Craner, Matthew J; McMahon, Róisín M; Jensen, Lise Torp; Huygelen, Véronique; Jones, E Yvonne; Bell, John I; Fugger, Lars.

    In: Nature Medicine, Vol. 14, No. 11, 2008, p. 1227-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Redirecting Therapeutic T Cells against Myelin-Specific T Lymphocytes Using a Humanized Myelin Basic Protein-HLA-DR2-{zeta} Chimeric Receptor. / Moisini, Ioana; Nguyen, Phuong; Fugger, Lars; Geiger, Terrence L.

    In: Journal of Immunology, Vol. 180, No. 5, 2008, p. 3601-3611.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. 2007
  80. Published

    Control of hypothalamic orexin neurons by acid and CO2. / Williams, Rhîannan H; Jensen, Lise T; Verkhratsky, Alex; Fugger, Lars; Burdakov, Denis.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 25, 19.06.2007, p. 10685-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. / Friese, MA; Cramer, MJ; Etzensperger, R; Vergo, S; Wemmie, JA; Welsh, MJ; Vincent, A; Fugger, Lars Henrik.

    In: Nat. Med, Vol. 13, No. 12, 2007, p. 1483-1489.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  82. Published

    T cells and microglia as drivers of multiple sclerosis pathology. / Friese, M A; Fugger, Lars Henrik.

    In: Brain, Vol. 130, 2007, p. 2755-2757.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  83. 2006
  84. Published

    Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose. / Burdakov, Denis; Jensen, Lise T; Alexopoulos, Haris; Williams, Rhiannan H; Fearon, Ian M; O'Kelly, Ita; Gerasimenko, Oleg; Fugger, Lars; Verkhratsky, Alexei.

    In: Neuron, Vol. 50, No. 5, 01.06.2006, p. 711-22.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. Published

    A role for tandem-pore K+ channels in hypothalamic sensing of glucose. / Burdakov, D.; Jensen, Lise Torp; Alexopoulos, H.; Gerasimenko, O.; Fugger, Lars Henrik; Verkhratsky, A.

    In: Neuron, Vol. 50, 2006, p. 711-722.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  86. Published

    Characterization of myelin oligodendrocyte glycoprotein epitopes presented by astrocytes from HLA-DR2 and HLA-DR4-transgenic mice. / Kort, J. J.; Fugger, Lars Henrik; Weissert, R.; Forsthuber, T. G.

    In: J. Neuroimmunology, Vol. 173, 2006, p. 23-34.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  87. Published

    Conflicting selective forces affect CD8+ T-cell receptor contact sites in an HLA-A2-immunodominant HIV epitope. / Fugger, Astrid Iversen; Stewart-Jones, G.; Learn, G. H.; Christie, N.; Sylvester-Hviid, C.; Armitage, A. E.; Kaul, R.; Beattie, T.; Lee, J. K.; Li, Y.; Chotiyarnwong, P.; Dong, T.; Xu, X.; Luscher, M. A.; MacDonald, K.; Ullum, H.; Klarund-Pedersen, B.; Skinhøj, P.; Fugger, Lars Henrik; Buus, S.; Mullins, J. I.; Jones, E. Y.; van der Merwe, P. A.; McMichael, A. J.

    In: Nature, Vol. 7, 2006, p. 179-189.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  88. Published

    Functional epistasis on a common MHC haplotype associated with multiple sclerosis. / Gregersen, Jon Waarst; Kranc, Kamil R.; Ke, Xiayi; Svendsen, Pia; Madsen, Lars; Thomsen, Allan Randrup; Cardon, Lon R.; Bell, John I.; Fugger, Lars Henrik.

    In: Nature, Vol. 443, 2006, p. 574-577.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. Published

    Humanized mouse models for organ-specific autoimmune diseases. / Friese, M.A.; Jensen, Lise Torp; Fugger, Lars Henrik.

    In: Curr Opinion Immunol, Vol. 18, No. 6, 2006, p. 704-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  90. Published

    MHC class II proteins and disease: a structural perspective. / Jones, E. Y.; Fugger, Lars Henrik; Strominger, J. L.; Siebold, C.

    In: Nat Rev Immunol, Vol. 6, No. 4, 2006, p. 271-282.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  91. Published

    The value of animal models for drug development in multiple sclerosis. / Friese, M.; Montalban, X.; John, I.; Bell, J. I.; Martin, R.; Fugger, Lars Henrik.

    In: Brain, Vol. 129, 2006, p. 1940-1952.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  92. Published

    Therapeutic vaccination against active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules. / Dzhambazov, B.; Nandakumar, K. S.; Kihlberg, J.; Fugger, Lars Henrik; Holmdahl, R.; Vestberg, M.

    In: Journal of Imunology, Vol. 1, 2006, p. 1525-1533.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  93. 2005
  94. Published

    Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? / Friese, M. A.; Fugger, Lars Henrik.

    In: Brain, Vol. 128, 2005, p. 1747-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  95. Published

    Control of autoimmunity by "epitope theft" / Kranc, K. R.; Taylor, A. M.; Wilcox, N.; Fugger, Lars Henrik.

    In: Trends. Mol. Med., Vol. 11, No. 1, 2005, p. 1-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  96. Published

    MHC II molecules in inflammatory diseases: interplay of qualitities and quantities. / Friese, M.A.; Jones, E.Y.; Fugger, Lars Henrik.

    In: Trends Immunol., Vol. 26, No. 11, 2005, p. 559-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  97. Published

    Multiple sclerosis: MHC associataions and therapeutic implications. / Holmes, S.; Siebold, C.; Jones, E. Y.; Friese, M. A.; Fugger, Lars Henrik; Bell, J.

    In: Expert Rev Mol Med, Vol. 7, No. 3, 2005, p. 1-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  98. 2004
  99. Published

    Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice. / Svendsen, Pia; Andersen, Claus B; Willcox, Nick; Coyle, Anthony J; Holmdahl, Rikard; Kamradt, Thomas; Fugger, Lars; Svendsen, Pia.

    In: Journal of Immunology, Vol. 173, No. 11, 01.12.2004, p. 7037-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  100. Published

    Collagen specific Th cells with proinflammatory capacities are detectable only very early in the disease course of callogen induced arthritis. / Svendsen, Pia; Andersen, C.B.; Willcox, N.; Coyle, A.J.; Holmdahl, R.; Kamradt, T.; Fugger, L.

    In: J. Immunol., Vol. 173, 2004, p. 7037-7045.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  101. Published

    Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. / Siebold, C.; Hansen, B.E.; Wyer, J.R.; Harlos, K.; Esnouf, R.; Svejgaard, A.; Bell, J.I.; Strominger, J.L.; Jones, E.Y; Fugger, L.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, 2004, p. 166-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  102. Published

    Efficient purification of unique antibodies using peptide columns. / Brix Jensen, L.; Riise, E.; Nielsen, L.K.; Dziegiel, M.; Fugger, L.; Engberg, J.

    In: J Immunological Methods, Vol. 284, 2004, p. 45-54.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  103. Published

    Humanized animal models for autoimmune diseases. / Gregersen, Jon Waarst; Holmes, S.; Fugger, L.

    In: HLA, Vol. 63, 2004, p. 383-394.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  104. Published
  105. Published

    Myelin oligodendrocyte glycoprotein-35-55 peptide, but not myelin basic protein-87-99 peptide, induces severe chronic experimental autoimmune encephalomyelititis in HLA-DR2 transgenic mice. / Rich, C.; Zamora, A.; Jacobsen, H.; Offner, H.; Jones, R.; Fugger, L.; Vandenbark, A.A.

    In: Eur. J. Immunol., Vol. 34, 2004, p. 1251-1261.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  106. 2003
  107. Published

    Limited protective effect of the CCR5Delta32/CCR5Delta32 genotype on human immunodeficiency virus infection incidence in a cohort of patients with hemophilia and selection for genotypic X4 virus. / Iversen, Astrid K. N.; Christiansen, Claus Bohn; Attermann, Jørn; Eugen-Olsen, Jesper; Schulman, Sam; Berntorp, Erik; Ingerslev, Jørgen; Fugger, Lars; Scheibel, Elma; Tengborn, Lillian; Gerstoft, Jan; Dickmeiss, Ebbe; Svejgaard, Arne; Skinhøj, Peter.

    In: Journal of Infectious Diseases, Vol. 187, No. 2, 15.01.2003, p. 215-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. Published

    Deficiency of mannan-binding lectin-associated serine protease-2 (MASP-2) in a patient with a history of infections and immunological disease. / Stengaard-Pedersen, K.; Thiel, S.; Jensen, L.T.; Sjöholm, A.G.; Fugger, L.; Jensenius, J.C.

    In: N. Engl. J. Med., Vol. 349, 2003, p. 554-560.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  109. Published

    Inherited deficiency of mannan-binding lectin-associated serine protease 2. / Stengaard-Pedersen, Kristian; Thiel, Steffen; Gadjeva, Mihaela; Møller-Kristensen, Mette; Sørensen, Rikke; Jensen, Lise Torp; Sjøholm, Anders G; Fugger, Lars; Jensenius, Jens Christian.

    In: The New England Journal of Medicine, Vol. 349, No. 6, 2003, p. 554-60.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  110. Published

    Limited protective effect of the CCR5Δ32/CCR5Δ32 genotype on human immunodeficiency virus infection incidence in a cohort of patients with hemophilia and selection for genotypic X4 virus. / Iversen, Astrid K. N.; Christiansen, Claus Bohn; Attermann, Jørn; Eugen-Olsen, Jesper; Schulman, Sam; Berntop, Erik; Ingerslev, Jørgen; Fugger, Lars Henrik; Scheibel, Elma; Tengborn, Lillian; Gerstoft, Jan; Dickmeiss, Ebbe; Svejgaard, Arne; Skinhøj, Peter.

    In: Journal of Infectious Diseases, Vol. 187, No. 2, 2003, p. 215-225.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  111. Published

    Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice. / Vandenbark, A.A.; Rich, C.; Mooney, J.; Zamora, A.; Wang, C.; Huan, J.; Fugger, L.; Offner, H.; Jones, R.; Burrows, G.G.

    In: J. Immunol., Vol. 171, 2003, p. 127-133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  112. Published

    The nature of molecular recognition by T cells. / Davis, S.J.; Ikemizu, S.; Evans, E.J.; Fugger, L.; Bakker, T.R.; Merwe van der, P.

    In: Nature Immunology, Vol. 4, 2003, p. 217-224.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  113. 2002
  114. Published

    A functional and structural basis for T cell receptor crossreactivity in multiple sclerosis. / Lang, H.; Jacobsen, H.; Ikemizu, S.; Andersson, C.; Harlos, K.; Madsen, L.; Hjorth, P.; Søndergaard, L.; Svejgaard, A.; Wucherpfennig, K.; Stuart, D.I.; Bell, J.I.; Jones, E.Y.; Fugger, L.

    In: Nature Immunology, Vol. 3, 2002, p. 940-943.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  115. Published

    A functional and structural basis for TCR cross-reactivity in multiple sclerosis. / Lang, H.L.E.; Jacobsen, H.; Ikemizy, S.; Anderson, C.; Harlos, K.; Madsen, L.; Hjorth, Jens Peter; Søndergaard, L.; Svejgaard, A.; Wucherpfennig, K.; Stuart, D.I.; Bell, J.I.; Jones, E.Y.; Fugger, Lars Henrik.

    In: Nature Immunology, Vol. 3, 2002, p. 940-943.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  116. Published

    Destructive processing by asparagine endopeptidase limits the level of presentation of a dominant T cell epitope in myelin basic protein. / Manoury, B.; Mazzeo, D.; Fugger, L.; Viner, N.; Ponsford, M.; Streeter, H.; Mazza, G.; Wraith, D.C.; Watts, C.

    In: Nature Immunology, Vol. 2, 2002, p. 169-174.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  117. Published

    Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis. / Fridkis-Hareli, M.; Santambrogio, L.; Stern, J.N.; Fugger, L.; Brosnan, C.; Strominger, J.L.

    In: The Journal of Clinical Investigation, Vol. 109, 2002, p. 1635-1643.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  118. Published

    Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis. / Bäcklund, J.; Carlsen, J.; Höger, T.; Holm, B.; Fugger, L.; Kihlberg, J.; Burkhardt, H.; Holmdahl, R.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, 2002, p. 9960-9965.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  119. 2001
  120. Published

    Synthetic peptides that inhibit binding of the myelin basic protein 85-99 epitope to multiple sclerosis-associated HLA-DR2 molecules and MBP-specific T-cell responses. / Fridkis-Hareli, M.; Stern, J.N.; Fugger, Lars Henrik; Strominger, J.L.

    In: Human Immunology, Vol. 62, 2001, p. 753-763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

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