Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs. / Xiang, Xi; Zhao, Xiaoying; Pan, Xiaoguang; Dong, Zhanying; Yu, Jiaying; Li, Siyuan; Liang, Xue; Han, Peng; Qu, Kunli; Jensen, Jonas Brorson; Farup, Jean; Wang, Fei; Petersen, Trine Skov; Bolund, Lars; Teng, Huajing; Lin, Lin; Luo, Yonglun.
In: Molecular Therapy - Nucleic Acids, Vol. 24, 06.2021, p. 403-415.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
GNL-Scorer : A generalized model for predicting CRISPR on-target activity by machine learning and featurization. / Wang, Jun; Xiang, Xi; Bolund, Lars; Zhang, Xiuqing; Cheng, Lixin; Luo, Yonglun.
In: Molecular and Cellular Biology, Vol. 12, No. 11, 11.2020, p. 909-911.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis. / Rohlenova, Katerina; Goveia, Jermaine; García-Caballero, Melissa; Subramanian, Abhishek; Kalucka, Joanna; Treps, Lucas; Falkenberg, Kim D; de Rooij, Laura P M H; Zheng, Yingfeng; Lin, Lin; Sokol, Liliana; Teuwen, Laure-Anne; Geldhof, Vincent; Taverna, Federico; Pircher, Andreas; Conradi, Lena-Christin; Khan, Shawez; Stegen, Steve; Panovska, Dena; De Smet, Frederik; Staal, Frank J T; Mclaughlin, Rene J; Vinckier, Stefan; Van Bergen, Tine; Ectors, Nadine; De Haes, Patrik; Wang, Jian; Bolund, Lars; Schoonjans, Luc; Karakach, Tobias K; Yang, Huanming; Carmeliet, Geert; Liu, Yizhi; Thienpont, Bernard; Dewerchin, Mieke; Eelen, Guy; Li, Xuri; Luo, Yonglun; Carmeliet, Peter.
In: Cell Metabolism, Vol. 31, No. 4, 04.2020, p. 862-877.e14.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-Cell Transcriptome Atlas of Murine Endothelial Cells. / Kalucka, Joanna; de Rooij, Laura P M H; Goveia, Jermaine; Rohlenova, Katerina; Dumas, Sébastien J; Meta, Elda; Conchinha, Nadine V; Taverna, Federico; Teuwen, Laure-Anne; Veys, Koen; García-Caballero, Melissa; Khan, Shawez; Geldhof, Vincent; Sokol, Liliana; Chen, Rongyuan; Treps, Lucas; Borri, Mila; de Zeeuw, Pauline; Dubois, Charlotte; Karakach, Tobias K; Falkenberg, Kim D; Parys, Magdalena; Yin, Xiangke; Vinckier, Stefan; Du, Yuxiang; Fenton, Robert A; Schoonjans, Luc; Dewerchin, Mieke; Eelen, Guy; Thienpont, Bernard; Lin, Lin; Bolund, Lars; Li, Xuri; Luo, Yonglun; Carmeliet, Peter.
In: Cell, Vol. 180, No. 4, 02.2020, p. 764-779.e20.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation. / Dumas, Sébastien J; Meta, Elda; Borri, Mila; Goveia, Jermaine; Rohlenova, Katerina; Conchinha, Nadine V; Falkenberg, Kim; Teuwen, Laure-Anne; de Rooij, Laura; Kalucka, Joanna; Chen, Rongyuan; Khan, Shawez; Taverna, Federico; Lu, Weisi; Parys, Magdalena; De Legher, Carla; Vinckier, Stefan; Karakach, Tobias K; Schoonjans, Luc; Lin, Lin; Bolund, Lars; Dewerchin, Mieke; Eelen, Guy; Rabelink, Ton J; Li, Xuri; Luo, Yonglun; Carmeliet, Peter.
In: Journal of the American Society of Nephrology : JASN, Vol. 31, No. 1, 01.2020, p. 118-138.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates. / Goveia, Jermaine; Rohlenova, Katerina; Taverna, Federico; Treps, Lucas; Conradi, Lena-Christin; Pircher, Andreas; Geldhof, Vincent; de Rooij, Laura P M H; Kalucka, Joanna; Sokol, Liliana; García-Caballero, Melissa; Zheng, Yingfeng; Qian, Junbin; Teuwen, Laure-Anne; Khan, Shawez; Boeckx, Bram; Wauters, Els; Decaluwé, Herbert; De Leyn, Paul; Vansteenkiste, Johan; Weynand, Birgit; Sagaert, Xavier; Verbeken, Erik; Wolthuis, Albert; Topal, Baki; Everaert, Wouter; Bohnenberger, Hanibal; Emmert, Alexander; Panovska, Dena; De Smet, Frederik; Staal, Frank J T; Mclaughlin, Rene J; Impens, Francis; Lagani, Vincenzo; Vinckier, Stefan; Mazzone, Massimiliano; Schoonjans, Luc; Dewerchin, Mieke; Eelen, Guy; Karakach, Tobias K; Yang, Huanming; Wang, Jian; Bolund, Lars; Lin, Lin; Thienpont, Bernard; Li, Xuri; Lambrechts, Diether; Luo, Yonglun; Carmeliet, Peter.
In: Cancer Cell, Vol. 37, No. 1, 2020, p. 21-36.e13.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
An atlas of the protein-coding genes in the human, pig, and mouse brain. / Sjöstedt, Evelina; Zhong, Wen; Fagerberg, Linn; Karlsson, Max; Mitsios, Nicholas; Adori, Csaba; Oksvold, Per; Edfors, Fredrik; Limiszewska, Agnieszka; Hikmet, Feria; Huang, Jinrong; Du, Yutao; Lin, Lin; Dong, Zhanying; Yang, Ling; Liu, Xin; Jiang, Hui; Xu, Xun; Wang, Jian; Yang, Huanming; Bolund, Lars; Mardinoglu, Adil; Zhang, Cheng; von Feilitzen, Kalle; Lindskog, Cecilia; Pontén, Fredrik; Luo, Yonglun; Hökfelt, Tomas; Uhlén, Mathias; Mulder, Jan.
In: Science, Vol. 367, No. 6482, 5947, 2020.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Haplotyping by CRISPR-mediated DNA circularization (CRISPR-hapC) broadens allele-specific gene editing. / Yu, Jiaying; Xiang, Xi; Huang, Jinrong; Liang, Xue; Pan, Xiaoguang; Dong, Zhanying; Petersen, Trine Skov; Qu, Kunli; Yang, Ling; Zhao, Xiaoying; Li, Siyuan; Zheng, Tianyu; Xu, Zhe; Liu, Chengxun; Han, Peng; Xu, Fengping; Yang, Huanming; Liu, Xin; Zhang, Xiuqing; Bolund, Lars; Luo, Yonglun; Lin, Lin.
In: Nucleic Acids Research, Vol. 48, No. 5, e25, 2020.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development. / Leng, Lizhi; Sun, Jiya; Huang, Jinrong; Gong, Fei; Yang, Ling; Zhang, Shuoping; Yuan, Xuye; Fang, Fang; Xu, Xun; Luo, Yonglun; Bolund, Lars; Peters, Brock A; Lu, Guangxiu; Jiang, Taijiao; Xu, Fengping; Lin, Ge.
In: Cell Stem Cell, Vol. 25, No. 5, 07.11.2019, p. 697-712.e6.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
LION : a simple and rapid method to achieve CRISPR gene editing. / Xiang, Xi; Luo, Lidan; Nodzyński, Michał; Li, Conghui; Han, Peng; Dou, Hongwei; Petersen, Trine Skov; Liang, Xue; Pan, Xiaoguang; Qu, Kunli; Yang, Ling; Dang, Yonghui; Liu, Xin; Bolund, Lars; Zhang, Xiuqing; Tong, Guangdong; Xing, Yufeng; Luo, Yonglun; Lin, Lin.
In: Cellular and Molecular Life Sciences, Vol. 76, No. 13, 07.2019, p. 2633-2645.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
CRISPR-C : circularization of genes and chromosome by CRISPR in human cells. / Møller, Henrik Devitt; Lin, Lin; Xiang, Xi; Petersen, Trine Skov; Huang, Jinrong; Yang, Luhan; Kjeldsen, Eigil; Jensen, Uffe Birk; Zhang, Xiuqing; Liu, Xin; Xu, Xun; Wang, Jian; Yang, Huanming; Church, George M; Bolund, Lars; Regenberg, Birgitte; Luo, Yonglun.
In: Nucleic Acids Research, Vol. 46, No. 22, 14.12.2018, p. e131.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Sex Differences in Genetic Associations With Longevity. / Zeng, Yi; Nie, Chao; Min, Junxia; Chen, Huashuai; Liu, Xiaomin; Ye, Rui; Chen, Zhihua; Bai, Chen; Xie, Enjun; Yin, Zhaoxue; Lv, Yuebin; Lu, Jiehua; Li, Jianxin; Ni, Ting; Bolund, Lars; Land, Kenneth C; Yashin, Anatoliy; O'Rand, Angela M; Sun, Liang; Yang, Ze; Tao, Wei; Gurinovich, Anastasia; Franceschi, Claudio; Xie, Jichun; Gu, Jun; Hou, Yong; Liu, Xiao; Xu, Xun; Robine, Jean-Marie; Deelen, Joris; Sebastiani, Paola; Slagboom, Eline; Perls, Thomas; Hauser, Elizabeth; Gottschalk, William; Tan, Qihua; Christensen, Kaare; Shi, Xiaoming; Lutz, Mike; Tian, Xiao-Li; Yang, Huanming; Vaupel, James.
In: JAMA network open, Vol. 1, No. 4, 08.2018.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
WEGO 2.0 : a web tool for analyzing and plotting GO annotations, 2018 update. / Ye, Jia; Zhang, Yong; Cui, Huihai; Liu, Jiawei; Wu, Yuqing; Cheng, Yun; Xu, Huixing; Huang, Xingxin; Li, Shengting; Zhou, An; Zhang, Xiuqing; Bolund, Lars; Chen, Qiang; Wang, Jian; Yang, Huanming; Fang, Lin; Shi, Chunmei.
In: Nucleic Acids Research, Vol. 46, No. W1, 02.07.2018, p. W71-W75.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / Zhao, Xin; Liu, Xiaomin; Zhang, Aiping; Chen, Huashuai; Huo, Qing; Li, Weiyang; Ye, Rui; Chen, Zhihua; Liang, Liping; Liu, Qiong A; Shen, Juan; Jin, Xin; Li, Wenwen; Nygaard, Marianne; Liu, Xiao; Hou, Yong; Ni, Ting; Bolund, Lars; Gottschalk, William; Tao, Wei; Gu, Jun; Tian, Xiao-Li; Yang, Huanming; Wang, Jian; Xu, Xun; Lutz, Michael W; Min, Junxia; Zeng, Yi; Nie, Chao.
In: Aging, Vol. 10, No. 6, 05.06.2018, p. 1206-1222.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases. / Lin, Lin; Liu, Yong; Xu, Fengping; Huang, Jinrong; Daugaard, Tina Fuglsang; Petersen, Trine Skov; Hansen, Bettina; Ye, Lingfei; Zhou, Qing; Fang, Fang; Yang, Ling; Li, Shengting; Fløe, Lasse; Jensen, Kristopher Torp; Shrock, Ellen; Chen, Fang; Yang, Huanming; Wang, Jian; Liu, Xin; Xu, Xun; Bolund, Lars; Nielsen, Anders Lade; Luo, Yonglun.
In: GigaScience, Vol. 7, No. 3, 01.03.2018, p. 1-19.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Central and peripheral nervous system progenitors derived from human pluripotent stem cells reveal a unique temporal and cell-type specific expression of PMCAs. / Chen, Muwan; Laursen, Sofie H.; Habekost, Mette; Knudsen, Camilla H.; Buchholdt, Susanne H.; Huang, Jinrong; Xu, Fengping; Liu, Xin; Bolund, Lars; Luo, Yonglun; Nissen, Poul; Febbraro, Fabia; Denham, Mark.
In: Frontiers in Cell and Developmental Biology, Vol. 6, 5, 06.02.2018.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs. / Shim, Jeong; Poulsen, Christian Bo; Hagensen, Mette; Larsen, Torben; Heegaard, P.M.H.; Christoffersen, Christina; Bolund, Lars; Schmidt, Mette; Liu, Ying; Li, Juan; Li, Rong; Callesen, Henrik; Bentzon, Jacob Fog; Sørensen, Charlotte Brandt.
In: Transgenic Research, Vol. 27, 2018, p. 484.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
BS-virus-finder : virus integration calling using bisulfite sequencing data. / Gao, Shengjie; Hu, Xuesong; Xu, Fengping; Gao, Changduo; Xiong, Kai; Zhao, Xiao; Chen, Haixiao; Zhao, Shancen; Wang, Mengyao; Fu, Dongke; Zhao, Xiaohui; Bai, Jie; Mao, Likai; Li, Bo; Wu, Song; Wang, Jian; Li, Shengbin; Yang, Huangming; Bolund, Lars; Pedersen, Christian N S.
In: GigaScience, 2018.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate non-invasive prenatal testing. / Chen, Fang; Liu, Ping; Gu, Ying; Zhu, Zhu; Nanisetti, Amulya; Lan, Zhangzhang; Huang, Zhiwei; Liu, Jia Sophie; Kang, Xiongbin; Deng, Yuqing; Luo, Liqiong; Jiang, Dan; Qiu, Yong; Pan, Jianchang; Xia, Jun; Xiong, Ken; Liu, Chao; Xie, Lin; Shi, Qianyu; Li, Jing; Zhang, Xiuqing; Wang, Wei; Drmanac, Snezana; Bolund, Lars; Jiang, Hui; Drmanac, Radoje; Xu, Xun.
In: Prenatal Diagnosis, Vol. 37, No. 13, 01.12.2017, p. 1311-1321.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Sequencing and de novo assembly of 150 genomes from Denmark as a population reference. / Maretty, Lasse; Jensen, Jacob Malte; Petersen, Bent; Sibbesen, Jonas Andreas; Liu, Siyang; Villesen, Palle; Skov, Laurits; Belling, Kirstine Christensen; Theil Have, Christian; Izarzugaza, José M G; Grosjean, Marie; Bork-Jensen, Jette; Grove, Jakob; Als, Thomas D; Huang, Shujia; Chang, Yuqi; Xu, Ruiqi; Ye, Weijian; Rao, Junhua; Guo, Xiaosen; Sun, Jihua; Cao, Hongzhi; Ye, Chen; van Beusekom, Johan; Espeseth, Thomas; Flindt, Esben Nørgaard; Friborg, Rune M; Halager, Anders E; Le Hellard, Stephanie; Hultman, Christina M; Lescai, Francesco; Li, Shengting; Lund, Ole; Løngren, Peter; Mailund, Thomas; Matey-Hernandez, Maria Luisa; Mors, Ole; Pedersen, Christian N S; Sicheritz-Ponten, Thomas; Sullivan, Patrick F; Syed, Ali; Westergaard, David; Yadav, Rachita; Li, Ning; Xu, Xun; Hansen, Torben; Krogh, Anders; Bolund, Lars; Sørensen, Thorkild I A; Pedersen, Oluf; Gupta, Ramneek; Rasmussen, Simon; Besenbacher, Søren; Børglum, Anders D; Wang, Jun; Eiberg, Hans; Kristiansen, Karsten; Brunak, Søren; Schierup, Mikkel Heide.
In: Nature, Vol. 548, 03.08.2017, p. 87-91.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Psoriasiform skin disease in transgenic pigs with high-copy ectopic expression of human integrins α2 and β1. / Staunstrup, Nicklas Heine; Stenderup, Karin; Mortensen, Sidsel; Nascimento Primo, Maria; Rosada, Cecilia; Steiniche, Torben; Liu, Ying; Li, Rong; Schmidt, Mette; Purup, Stig; Dagnæs-Hansen, Frederik; Schrøder, Lisbeth Dahl; Svensson, Lars; Petersen, Thomas Kongstad; Callesen, Henrik; Bolund, Lars; Mikkelsen, Jacob Giehm.
In: Disease Models & Mechanisms, Vol. 10, 01.07.2017, p. 869-880.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Chromatin accessibility and guide sequence secondary structure affect CRISPR-Cas9 gene editing efficiency. / Jensen, Kristopher Torp; Fløe, Lasse; Petersen, Trine Skov; Huang, Jinrong; Xu, Fengping; Bolund, Lars; Luo, Yonglun; Lin, Lin.
In: FEBS Letters, Vol. 591, No. 13, 05.06.2017, p. 1892-1901.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts. / Xiong, Kai; Zhou, Yan; Blichfeld, Kristian Aabo; Hyttel, Poul; Bolund, Lars; Freude, Karla Kristine; Luo, Yonglun.
In: Cellular reprogramming, Vol. 19, No. 3, 06.2017, p. 189-198.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder. / Lescai, F; Als, T D; Li, Q; Nyegaard, M; Andorsdottir, Gudrid; Biskopstø, Marjun; Hedemand, A; Fiorentino, A; O'Brien, Niamh L; Jarram, Alex; Liang, T J; Grove, J; Pallesen, J; Eickhardt, E; Mattheisen, M; Bolund, L; Demontis, D; Wang, A G; McQuillin, A.; Mors, O; Wang, J; Børglum, A D.
In: Translational Psychiatry, Vol. 7, No. 2, 14.02.2017, p. e1034.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Mitochondrial Spare Respiratory Capacity Is Negatively Correlated With Nuclear Reprogramming Efficiency. / Zhou, Yan; Al-Saaidi, Rasha Abdelkadhem; Guerra, Paula Fernandez; Freude, Kristine Karla; Olsen, Rikke Katrine Jentoft; Jensen, Uffe Birk; Gregersen, Niels; Hyttel, Poul; Bolund, Lars; Aagaard, Lars; Bross, Peter; Luo, Yonglun.
In: Stem Cells and Development, Vol. 26, No. 3, 02.2017, p. 166-176.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs. / Shim, Jeong; Poulsen, Christian Bo; Hagensen, Mette K; Larsen, Torben; Heegaard, Peter M H; Christoffersen, Christina; Bolund, Lars; Schmidt, Mette; Liu, Ying; Li, Juan; Li, Rong; Callesen, Henrik; Bentzon, Jacob Fog; Sørensen, Charlotte Brandt.
In: JACC: Basic to translational science, Vol. 2, No. 5, 2017, p. 591-600.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Fusion of SpCas9 to E.coli Rec A protein enhances CRISPR-Cas9 mediated gene knockout in mammalian cells. / Lin, Lin; Petersen, Trine Skov; Jensen, Kristopher Torp; Bolund, Lars; Kühn, Ralf; Luo, Yonglun.
In: Journal of Biotechnology, Vol. 247, 2017, p. 42-29.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B. / Zhang, Yu; Schmid, Benjamin; Nikolaisen, Nanett Kvist; Rasmussen, Mikkel A; Aldana, Blanca I; Agger, Mikkel; Calloe, Kirstine; Stummann, Tina C; Larsen, Hjalte M; Nielsen, Troels T; Huang, Jinrong; Xu, Fengping; Liu, Xin; Bolund, Lars; Meyer, Morten; Bak, Lasse K; Waagepetersen, Helle S; Luo, Yonglun; Nielsen, Jørgen E; Holst, Bjørn; Clausen, Christian; Hyttel, Poul; Freude, Kristine K; FReJA Consortium.
In: Stem Cell Reports, Vol. 8, No. 3, 2017.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells. / Secher, Jan O; Ceylan, Ahmet; Mazzoni, Gianluca; Mashayekhi, Kaveh; Li, Tong; Muenthaisong, Suchitra; Nielsen, Troels T; Li, Dong; Li, Shengting; Petkov, Stoyan; Cirera, Susanna; Luo, Yonglun; Thombs, Lori; Kadarmideen, Haja N; Dinnyes, Andras; Bolund, Lars; Roelen, Bernard A J; Schmidt, Mette; Callesen, Henrik; Hyttel, Poul; Freude, Kristine K.
In: Molecular Reproduction and Development, Vol. 84, No. 3, 2017, p. 229-245.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM). / Xiong, Kai; Zhou, Yan; Hyttel, Poul; Bolund, Lars; Freude, Kristine Karla; Luo, Yonglun.
In: Stem Cell Research, Vol. 17, No. 3, 17.11.2016, p. 665-669.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Production of Pigs by Hand-Made Cloning Using Mesenchymal Stem Cells and Fibroblasts. / Yang, Zhenzhen; Vajta, Gábor; Xu, Ying; Luan, Jing; Lin, Mufei; Liu, Cong; Tian, Jianing; Dou, Hongwei; Li, Yong; Liu, Tianbin; Zhang, Yijie; Li, Lin; Yang, Wenxian; Bolund, Lars; Yang, Huanming; Du, Yutao.
In: Cellular reprogramming, Vol. 18, No. 4, 08.2016, p. 256-63.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Golden Gate Assembly of CRISPR gRNA expression array for simultaneously targeting multiple genes. / Vad-Nielsen, Johan; Lin, Lin; Bolund, Lars; Nielsen, Anders Lade; Luo, Yonglun.
In: Cellular and Molecular Life Sciences, Vol. 73, No. 22, 13.05.2016, p. 4315–4325.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Pig model for diabetes. / Luo, Yonglun (Inventor); Bolund, Lars (Inventor).
Mar 03, 2016.Research output: Patent
Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system. / Zhou, Yan; Liu, Yong; Hussmann, Dianna; Brøgger, Peter; Al-Saaidi, Rasha Abdelkadhem; Tan, Shuang; Lin, Lin; Petersen, Trine Skov; Zhou, Guang Qian; Bross, Peter; Aagaard, Lars; Klein, Tino; Rønn, Sif Groth; Pedersen, Henrik Duelund; Bolund, Lars; Nielsen, Anders Lade; Sørensen, Charlotte Brandt; Luo, Yonglun.
In: Cellular and Molecular Life Sciences, Vol. 73, No. 13, 11.01.2016, p. 2543-63.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Interaction between FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages. / Zeng, Yi; Chen, Huashuai; Ni, Ting; Ruan, Rongping; Nie, Chao; Liu, Xiaomin; Feng, Lei; Zhang, Fengyu; Lu, Jiehua; Li, Jianxin; Li, Yang; Tao, Wei; Gottschalk, William; Lutz, Mike; Land, Kenneth; Yashin, Anatoli I; Tan, Qihua; Yang, Ze; Bolund, Lars; Qi, Ming; Yang, Huanming; Min, Junxia; Willcox, Craig D; Willcox, Bradley; Gu, Jun; Hauser, Elizabeth; Tian, Xiao-Li; Vaupel, James W.
In: Rejuvenation Research, Vol. 19, No. 3, 2016, p. 195-203.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Novel loci and pathways significantly associated with longevity. / Zeng, Yi; Nie, Chao; Min, Junxia; Liu, Xiaomin; Li, Mengmeng; Chen, Huashuai; Xu, Hanshi; Wang, Mingbang; Ni, Ting; Li, Yang; Yan, Han; Zhang, Jin-Pei; Song, Chun; Chi, Li-Qing; Wang, Han-Ming; Dong, Jie; Zheng, Gu-Yan; Lin, Li; Qian, Feng; Qi, Yanwei; Liu, Xiao; Cao, Hongzhi; Wang, Yinghao; Zhang, Lijuan; Li, Zhaochun; Zhou, Yufeng; Wang, Yan; Lu, Jiehua; Li, Jianxin; Qi, Ming; Bolund, Lars; Yashin, Anatoliy; Land, Kenneth C; Gregory, Simon; Yang, Ze; Gottschalk, William; Tao, Wei; Wang, Jian; Wang, Jun; Xu, Xun; Bae, Harold; Nygaard, Marianne; Christiansen, Lene; Christensen, Kaare; Franceschi, Claudio; Lutz, Michael W; Gu, Jun; Tan, Qihua; Perls, Thomas; Sebastiani, Paola; Deelen, Joris; Slagboom, Eline; Hauser, Elizabeth; Xu, Huji; Tian, Xiao-Li; Yang, Huanming; Vaupel, James W.
In: Scientific Reports, Vol. 6, 2016, p. 21243.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells. / Hansen, Stine Ninel; Ehlers, Natasja Spring; Zhu, Shida; Thomsen, Mathilde Borg Houlberg; Nielsen, Rikke Linnemann; Liu, Dongbing; Wang, Guangbiao; Hou, Yong; Zhang, Xiuqing; Xu, Xun; Bolund, Lars; Yang, Huanming; Wang, Jun; Moreira, Jose; Ditzel, Henrik J; Brünner, Nils; Schrohl, Anne-Sofie; Stenvang, Jan; Gupta, Ramneek.
In: B M C Genomics, Vol. 17, No. 1, 2016, p. 442.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Factors Determining the Efficiency of Porcine Somatic Cell Nuclear Transfer : Data Analysis with Over 200,000 Reconstructed Embryos. / Liu, Tianbin; Dou, Hongwei; Xiang, Xi; Li, Lin; Li, Yong; Lin, Lin; Pang, Xinzhi; Zhang, Yijie; Chen, Yu; Luan, Jing; Xu, Ying; Yang, Zhenzhen; Yang, Wenxian; Liu, Huan; Li, Feida; Wang, Hui; Yang, Huanming; Bolund, Lars; Vajta, Gabor; Du, Yutao.
In: Cellular reprogramming, Vol. 17, No. 6, 12.2015, p. 463-71.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Transgenic Wuzhishan minipigs designed to express a dominant-negative porcine growth hormone receptor display small stature and a perturbed insulin/IGF-1 pathway. / Li, Feida; Li, Yong; Liu, Huan; Zhang, Xingju; Liu, Chuxin; Tian, Kai; Bolund, Lars; Dou, Hongwei; Yang, Wenxian; Yang, Huanming; Staunstrup, Nicklas Heine; Du, Yutao.
In: Transgenic Research, Vol. 24, No. 6, 12.2015, p. 1029-42.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions. / Luo, Yonglun; Friis, Jenny Blechingberg; Fernandes, Ana Miguel; Li, Shengting; Fryland, Tue; Børglum, Anders; Bolund, Lars; Nielsen, Anders Lade.
In: BMC Genomics, Vol. 16, 11.2015.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Paternal Hemizygosity in 11p15 in Mole-like Conceptuses : Two Case Reports. / Sunde, Lone; Lund, Helle; J Sebire, Neil; Grove, Anni; Fisher, Rosemary A; Niemann, Isa; Kjeldsen, Eigil; Andreasen, Lotte; Hansen, Estrid Staehr; Bojesen, Anders; Bolund, Lars; Nyegaard, Mette.
In: Medicine (Baltimore), Vol. 94, No. 44, 11.2015, p. e1776.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Identifying Rare Variation in Cases of Schizophrenia in the Isolated Population of the Faroe Islands using Whole-genome Sequencing. / Als, Thomas Damm; Lescai, Francesco; Dahl, Hans; Demontis, Ditte; Wang, August; Andorsdottir, Gudrid; Biskopstø, Marjun; Johansen, Oddbjørg; Grove, Jakob; Nyegaard, Mette; Bolund, Lars; Mors, Ole; Jun, Wang; Børglum, Anders.
2015. Poster session presented at XXIII World Congress of Psychiatric Genetics, Toronto, Canada.Research output: Contribution to conference › Poster › Research
BS-SNPer : SNP calling in Bisulfite-seq data. / Gao, Shengjie; Zou, Dan; Mao, Likai; Liu, Huayu; Song, Pengfei; Chen, Youguo; Zhao, Shancen; Gao, Changduo; Li, Xiangchun; Gao, Zhibo; Fang, Xiaodong; Yang, Huanming; Ørntoft, Torben F; Sørensen, Karina D; Bolund, Lars.
In: Bioinformatics (Online), Vol. 31, 28.08.2015.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Towards personalized regenerative cell therapy : Mesenchymal stem cells derived from human induced pluripotent stem cells. / Lin, Lin; Bolund, Lars; Luo, Yonglun.
In: Current Stem Cell Research & Therapy, 23.07.2015.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Imprinted Genes on Chromosome 6 Are Unlikely to Cause Hydatidiform Mole. A Report of Two Cases. / Scholz, Nanna Brink; Lund, Helle; Bolund, Lars; Sunde, Lone.
In: Journal of Reproductive Medicine, Vol. 60, No. 5-6, 02.07.2015, p. 261-4.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Pig model for atherosclerosis. Europe Patent EP2134847, June 24, 2015. / Bentzon, Jacob Fog (Inventor); Sørensen, Charlotte Brandt (Inventor); Kragh, Peter (Inventor); Mikkelsen, Jacob Giehm (Inventor); Falk, Erling (Inventor); Bolund, Lars (Inventor); Corydon, Thomas Juhl (Inventor).
Jun 24, 2015.Research output: Patent
De novo assembly of a haplotype-resolved human genome. / Cao, Hongzhi; Wu, Honglong; Luo, Ruibang; Huang, Shujia; Sun, Yuhui; Tong, Xin; Xie, Yinlong; Liu, Binghang; Yang, Hailong; Zheng, Hancheng; Li, Jian; Li, Bo; Wang, Yu; Yang, Fang; Sun, Peng; Liu, Siyang; Gao, Peng; Huang, Haodong; Sun, Jing; Chen, Dan; He, Guangzhu; Huang, Weihua; Huang, Zheng; Li, Yue; Tellier, Laurent C A M; Liu, Xiao; Feng, Qiang; Xu, Xun; Zhang, Xiuqing; Bolund, Lars; Krogh, Anders; Kristiansen, Karsten; Drmanac, Radoje; Drmanac, Snezana; Nielsen, Rasmus; Li, Songgang; Wang, Jian; Yang, Huanming; Li, Yingrui; Wong, Gane Ka-Shu; Wang, Jun.
In: Nature Biotechnology, Vol. 33, No. 6, 06.2015, p. 617-22.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The parental origin correlates with the karyotype of human embryos developing from tripronuclear zygotes. / Joergensen, Mette Warming; Labouriau, Rodrigo; Hindkjaer, Johnny; Stougaard, Magnus; Kolevraa, Steen; Bolund, Lars; Agerholm, Inge Errebo; Sunde, Lone.
In: Clinical and Experimental Reproductive Medicine, Vol. 42, No. 1, 03.2015, p. 14-21.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Paradigmeskifte i dansk sundhedsvidenskab: Nye muligheder i diagnostik og behandling. / Bolund, Lars; Brunak, Søren; Brünner, Nils; Børglum, Anders; Pedersen, Oluf Borbye; Danielsen, Inge ; Flindt, Esben Nørgaard; Hansen, Torben; Jespersen, Jørgen; Kristiansen, Karsten; Olesen, Peter; Sørensen, Thorkild; Ørntoft, Torben Falck.
In: Videnskab.dk, 20.01.2015.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Contribution to newspaper - Comment/debate
Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity. / Kang, Ran; Zhou, Yan; Tan, Shuang; Zhou, Guangqian; Aagaard, Lars; Xie, Lin; Bünger, Cody; Bolund, Lars; Luo, Yonglun.
In: Stem Cell Research & Therapy, Vol. 6, No. 1, 2015, p. 144.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. / Besenbacher, Søren; Liu, Siyang; Izarzugaza, José M G; Grove, Jakob; Belling, Kirstine; Bork-Jensen, Jette; Huang, Shujia; Als, Thomas D; Li, Shengting; Yadav, Rachita; Rubio-García, Arcadio; Lescai, Francesco; Demontis, Ditte; Rao, Junhua; Ye, Weijian; Mailund, Thomas; Møllegaard Friborg, Rune; Pedersen, Christian N S; Xu, Ruiqi; Sun, Jihua; Liu, Hao; Wang, Ou; Cheng, Xiaofang; Flores, David; Rydza, Emil; Rapacki, Kristoffer; Damm Sørensen, John; Chmura, Piotr; Westergaard, David; Dworzynski, Piotr; Sørensen, Thorkild I A; Lund, Ole; Hansen, Torben; Xu, Xun; Li, Ning; Bolund, Lars; Pedersen, Oluf; Eiberg, Hans; Krogh, Anders; Børglum, Anders D; Brunak, Søren; Kristiansen, Karsten; Schierup, Mikkel H; Wang, Jun; Gupta, Ramneek; Villesen, Palle; Rasmussen, Simon.
In: Nature Communications, Vol. 6, 5969, 2015.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
SMAP : a streamlined methylation analysis pipeline for bisulfite sequencing. / Gao, Shengjie; Zou, Dan; Mao, Likai; Zhou, Quan; Jia, Wenlong; Huang, Yi; Zhao, Shancen; Chen, Gang; Wu, Song; Li, Dongdong; Xia, Fei; Chen, Huafeng; Chen, Maoshan; Ørntoft, Torben F; Bolund, Lars; Sørensen, Karina D.
In: GigaScience, Vol. 4, 2015, p. 29.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Targeted Porcine Genome Engineering with TALENs. / Luo, Yonglun; Lin, Lin; Golas, Mariola Monika; Sørensen, Charlotte Brandt; Bolund, Lars.
Somatic Genome Manipulation : Advances, Methods and Applications. Springer New York, 2015. p. 17-33.Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review
The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer. / Lin, Xue; Stenvang, Jan; Rasmussen, Mads Heilskov; Zhu, Shida; Jensen, Niels Frank; Tarpgaard, Line S; Yang, Guangxia; Belling, Kirstine; Andersen, Claus Lindbjerg; Li, Jian; Bolund, Lars; Brünner, Nils.
In: B M C Genomics, Vol. 16, 2015, p. 404.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Triploidy-Observations in 154 Diandric Cases. / Scholz, Nanna Brink; Bolund, Lars; Nyegaard, Mette; Faaborg, Louise; Jørgensen, Mette Warming; Lund, Helle; Niemann, Isa; Sunde, Lone.
In: PLOS ONE, Vol. 10, No. 11, 2015, p. e0142545.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
GxE Interactions Between FOXO Genotypes and Tea Drinking Significantly Affect Cognitive Disability at Advanced Ages in China. / Zeng, Yi; Chen, Huashuai; Ni, Ting; Ruan, Rongping; Feng, Lei; Nie, Chao; Cheng, Lingguo; Li, Yang; Tao, Wei; Gu, Jun; Land, Kenneth C; Yashin, Anatoli; Tan, Qihua; Yang, Ze; Bolund, Lars; Yang, Huanming; Hauser, Elizabeth; Willcox, Craig D; Willcox, Bradley J; Tian, Xiao-Li; Vaupel, James W.
In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 03.06.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Efficient construction of rAAV-based gene targeting vectors by Golden Gate cloning. / Luo, Yonglun; Lin, Lin; Bolund, Lars; Sørensen, Charlotte Brandt.
In: BioTechniques, Vol. 56, No. 5, 05.2014, p. 263-8.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Health status and 6 years survival of 552 90+ Italian sib-ships recruited within the EU Project GEHA (GEnetics of Healthy Ageing). / Cevenini, E; Cotichini, R; Stazi, M A; Toccaceli, V; Palmas, M G; Capri, M; De Rango, F; Dato, S; Passarino, G; Jeune, B; Franceschi, C; GEHA Project Consortium ; Bolund, Lars.
In: Age (Omaha), Vol. 36, No. 2, 04.2014, p. 949-66.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Triploid pregnancies, genetic and clinical features of 158 cases. / Joergensen, Mette W; Niemann, Isa; Rasmussen, Anders A; Hindkjaer, Johnny; Agerholm, Inge; Bolund, Lars; Sunde, Lone.
In: American Journal of Obstetrics and Gynecology, 18.03.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method : A time-lapse study. / Joergensen, Mette Warming; Agerholm, Inge; Hindkjaer, Johnny; Bolund, Lars; Sunde, Lone; Ingerslev, Hans Jakob; Kirkegaard, Kirstine.
In: Journal of Assisted Reproduction and Genetics, 24.01.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population. / Li, Shengting; Besenbacher, Soren; Li, Yingrui; Kristiansen, Karsten; Grarup, Niels; Albrechtsen, Anders; Sparsø, Thomas Hempel; Korneliussen, Thorfinn Sand; Hansen, Torben; Wang, Jun; Nielsen, Rasmus; Pedersen, Oluf; Bolund, Lars; Schierup, Mikkel H.
In: European Journal of Human Genetics, 22.01.2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing. / Tan, Yueqiu; Yin, Xuyang; Zhang, Shuoping; Jiang, Hui; Tan, Ke; Li, Jian; Xiong, Bo; Gong, Fei; Zhang, Chunlei; Pan, Xiaoyu; Chen, Fang; Chen, Shengpei; Gong, Chun; Lu, Changfu; Luo, Keli; Gu, Yifan; Zhang, Xiuqing; Wang, Wei; Xu, Xun; Vajta, Gábor; Bolund, Lars; Yang, Huanming; Lu, Guangxiu; Du, Yutao; Lin, Ge.
In: GigaScience, Vol. 3, No. 1, 2014, p. 30.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Effects of high hydrostatic pressure on genomic expression profiling of porcine parthenogenetic activated and cloned embryos. / Lin, Lin; Luo, Yonglun; Sørensen, Peter; Prætorius, Helle; Vajta, Gabor; Callesen, Henrik; Pribenszky, Csaba; Bolund, Lars; Kristensen, Torsten Nygård.
In: Reproduction, Fertility and Development, Vol. 26, 2014, p. 469-484.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Efficient genome engineering using rAAV and TALENs in pigs. / Luo, Yonglun; Viuff, B M; Lin, Lin; Li, Rong; Schmidt, Mette; Rønn, S G; Pedersen, H. D.; Callesen, Henrik; Sørensen, Charlotte Brandt; Brünner, Niels; Klein, Tino; Bolund, Lars.
In: Transgenic Research, Vol. 23, No. 1, 2014, p. 189-190.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference article › Research › peer-review
Enrichment Analysis of Genomic features to Identify Genome-Wide Patterns of Insertions/Deletions in Cases of Psychiatric Disorders from the Faroe Islands. / Eickhardt, Esben Ahlburg; Als, Thomas Damm; Mattheisen, Manuel; Nyegaard, Mette; Demontis, Ditte; Grove, Jakob; Andorsdottir, Gudrid; Biskopstø, Marjun; Wang, August; Mors, Ole; Bolund, Lars; Wang, Jun; Børglum, Anders; Lescai, Francesco.
2014. Poster session presented at XXII World Congress of Psychiatric Genetics, København, Danmark, Denmark.Research output: Contribution to conference › Poster › Research › peer-review
Oesteogenesis of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells on hydroxyapatite contained Nanofibers. / Kang, Ran; Luo, Yonglun; Zou, Lijin; Xie, Lin; Lysdahl, Helle; Jiang, Xiumei; Chen, Chunying; Bolund, Lars; Chen, Menglin; Besenbacher, Flemming; Bunger, Cody Eric.
In: R S C Advances, Vol. 4, No. 11, 2014, p. 5734-5739.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Population Structure & Cryptic Relatedness of the isolated Population of the Faroe Islands. / Als, Thomas Damm; Lescai, Francesco; Dahl, Hans Atli; Grove, Jakob; Demontis, Ditte; Wang, August G.; Andorsdottir, Gudrid; Biskopstø, Marjun; Johansen, Oddbjørg; Nyegaard, Mette; Bolund, Lars; Mors, Ole; Wang, Jun; Børglum, Anders.
2014. Poster session presented at XXII World Congress of Psychiatric Genetics, København, Denmark.Research output: Contribution to conference › Poster › Research › peer-review
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. / Raule, Nicola; Sevini, Federica; Li, Shengting; Barbieri, Annalaura; Tallaro, Federica; Lomartire, Laura; Vianello, Dario; Montesanto, Alberto; Moilanen, Jukka S; Bezrukov, Vladyslav; Blanché, Hélène; Hervonen, Antti; Christensen, Kaare; Deiana, Luca; Gonos, Efstathios S; Kirkwood, Tom B L; Kristensen, Peter; Leon, Alberta; Pelicci, Pier Giuseppe; Poulain, Michel; Rea, Irene M; Remacle, Josè; Robine, Jean Marie; Schreiber, Stefan; Sikora, Ewa; Eline Slagboom, Peternella; Spazzafumo, Liana; Antonietta Stazi, Maria; Toussaint, Olivier; Vaupel, James W.; Rose, Giuseppina; Majamaa, Kari; Perola, Markus; Johnson, Thomas E; Bolund, Lars; Yang, Huanming; Passarino, Giuseppe; Franceschi, Claudio.
In: Aging Cell, 2014.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties. / Lin, Xue; Li, Jian; Yin, Guangliang; Zhao, Qian; Elias, Daniel; Lykkesfeldt, Anne E; Stenvang, Jan; Brünner, Nils; Wang, Jun; Yang, Huanming; Bolund, Lars; Ditzel, Henrik J.
In: Breast Cancer Research (Online Edition), Vol. 15, No. 6, 19.12.2013, p. R119.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
How to classify the oldest old according to their health status : a study on 1160 subjects belonging to 552 90+ Italian sib-ships characterized by familial longevity recruited within the GEHA EU Project. / Cevenini, Elisa; Cotichini, Rodolfo; Stazi, Maria Antonietta; Toccaceli, Virgilia; Scurti, Maria; Mari, Vincenzo; Berardelli, Maurizio; Passarino, Giuseppe; Jeune, Bernard; Franceschi, Claudio; GEHA Project Consortium ; Bolund, Lars.
In: Mechanisms of Ageing and Development, Vol. 134, No. 11-12, 26.11.2013, p. 560-9.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
NLRP7 or KHDC3L genes and the etiology of molar pregnancies and recurrent miscarriage. / Andreasen, L; Christiansen, O B; Niemann, I; Bolund, L; Sunde, Lone.
In: Molecular Human Reproduction, Vol. 19, No. 11, 11.2013, p. 773-81.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Pig model for atherosclerosis. United States Patent US 8,546,643. Oct 1, 2013. / Bentzon, Jacob Fog (Inventor); Sørensen, Charlotte Brandt (Inventor); Kragh, Peter (Inventor); Mikkelsen, Jacob Giehm (Inventor); Falk, Erling (Inventor); Bolund, Lars (Inventor); Corydon, Thomas Juhl (Inventor).
Oct 01, 2013.Research output: Patent
Methylation specific Multiplex Ligation-dependent Probe Amplification : utility for prenatal diagnosis of parental origin in human triploidy. / Joergensen, M W; Rasmussen, A A; Niemann, I; Hindkjaer, J; Agerholm, I; Bolund, Lars; Kolvraa, S; Sunde, L.
In: Prenatal Diagnosis, Vol. 33, No. 12, 24.07.2013, p. 1131-1136.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds. / Zou, Lijin; Luo, Yonglun; Chen, Muwan; Wang, Gang; Ding, Ming; Petersen, Charlotte Christie; Kang, Ran; Dagnaes-Hansen, Frederik; Zeng, Yuanlin; Lv, Nonghua; Ma, Qing; Le, Dang Quang Svend; Besenbacher, Flemming; Bolund, Lars; Jensen, Thomas G; Kjems, Jørgen; Pu, William T; Bünger, Cody.
In: Scientific Reports, Vol. 3, 2243, 22.07.2013.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Tetraploidy in hydatidiform moles. / Sundvall Germeys, Linda Karin M; Lund, Helle; Niemann, Isa; Jensen, Uffe Birk; Bolund, Lars; Sunde, Lone.
In: Human Reproduction, 30.04.2013.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
A lentiviral vector-based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin. / Staunstrup, Nicklas Heine; Bak, Rasmus Otkjær; Cai, Yujia; Svensson, Lars; Petersen, Anette Thomas; Rosada, Cecilia; Stenderup, Karin; Bolund, Lars; Mikkelsen, Jacob Giehm.
In: Experimental Dermatology, Vol. 22, No. 3, 22.03.2013, p. 178-83.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. / Albrechtsen, Anders; Grarup, N; Li, Y; Sparsø, Thomas Hempel; Tian, G; Cao, H; Jiang, Tao; Kim, S Y; Korneliussen, Thorfinn Sand; Li, Q; Nie, C; Wu, Rui; Skotte, Line; Morris, A P; Ladenvall, C; Cauchi, S; Stančáková, A; Andersen, G; Astrup, A; Banasik, Karina; Bennett, A J; Bolund, Lars; Charpentier, G; Chen, Yingke; Dekker, J M; Doney, A S F; Dorkhan, M; Forsen, T; Frayling, T M; Groves, C J; Gui, Y; Hallmans, G; Hattersley, A T; He, K; Hitman, G A; Holmkvist, J; Huang, Shaojun; Jiang, H; Jin, X; Justesen, J M; Kristiansen, K; Kuusisto, J; Lajer, Marianne; Lantieri, O; Li, W; Liang, H; Liao, Q; Liu, X; Lauritzen, T; Pedersen, O; D.E.S.I.R. Study Group.
In: Diabetologia, Vol. 56, No. 2, 02.2013, p. 298-310.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Development of transgenic minipigs with expression of antimorphic human cryptochrome 1. / Liu, Huan; Li, Yong; Wei, Qiang; Liu, Chunxin; Bolund, Lars; Vajta, Gábor; Dou, Hongwei; Yang, Wenxian; Xu, Ying; Luan, Jing; Wang, Jun; Yang, Huanming; Staunstrup, Nicklas Heine; Du, Yutao.
In: PLOS ONE, Vol. 8, No. 10, 2013, p. e76098.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant. / Al-Mashhadi, Rozh H; Sørensen, Charlotte B; Kragh, Peter M; Christoffersen, Christina; Mortensen, Martin B; Tolbod, Lars P; Thim, Troels; Du, Yutao; Li, Juan; Liu, Ying; Moldt, Brian; Schmidt, Mette; Vajta, Gabor; Larsen, Torben; Purup, Stig; Bolund, Lars; Nielsen, Lars B; Callesen, Henrik; Falk, Erling; Mikkelsen, Jacob Giehm; Bentzon, Jacob F.
In: Science Translational Medicine, Vol. 5, No. 166, 2013, p. 166ra1.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
How isolated is the Faroese population & what are the prospects of mapping complex psychiatric disorders? / Als, Thomas Damm; Lescai, Francesco; Grove, Jakob; Mattheisen, Manuel; Demontis, Ditte; Wang, August G.; Andorsdottir, Gudrid; Biskopstø, Marjun; Nyegaard, Mette; Bolund, Lars; Mors, Ole; Wang, Jun; Børglum, Anders.
2013. Poster session presented at XXIst World Congress of Psychiatric Genetics , Boston, Massachusetts, United States.Research output: Contribution to conference › Poster › Research › peer-review
Novel Methods in the Study of the Breast Cancer Genome: Towards a Better Understanding of the Disease of Breast Cancer. / Li, Jian; Lin, Xue; Brünner, Nils Aage; Yang, Huanming; Bolund, Lars.
In: Journal of Cancer Therapy, Vol. 3, 2013, p. 797-809.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
SOAPindel: efficient identification of indels from short paired reads. / Li, Shengting; Li, Ruiqiang; Li, Heng; Lu, Jianliang; Li, Yingrui; Bolund, Lars; Schierup, Mikkel Heide; Wang, Jun.
In: Genome Research, Vol. 23, No. 1, 2013, p. 195-200.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
The sequence and analysis of a Chinese pig genome. / Fang, Xiaodong; Mu, Yulian; Huang, Zhiyong; Li, Yong; Han, Lijuan; Zhang, Yanfeng; Feng, Yue; Chen, Yuanxin; Jiang, Xuanting; Zhao, Wei; Sun, Xiaoqing; Xiong, Zhiqiang; Yang, Lan; Liu, Huan; Fan, Dingding; Mao, Likai; Ren, Lijie; Liu, Chuxin; Wang, Juan ; Li, Kui; Wang, Guangbiao; Yang, Shunlin; Lai, Liangxue; Zhang, Guojie; Li, Yingrui; Wang, Jun; Bolund, Lars; Yang, Huanming; Wang, Jian; Feng, Shutang; Li, Songgang; Du, Yutao.
In: GigaScience, Vol. 1, No. 16, 2013.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer. / Li, Yingrui; Xu, Xun; Song, Luting; Hou, Yong; Li, Zesong; Tsang, Shirly; Li, Fugiang; McGee, Kate; Wu, Kui; Wu, Hanjie; Ye, Xiaofei; Li, Guibo; Wang, Linlin; Zhang, Bo; Liang, Jie; Xie, Wei; Wu, Renhua; Jiang, Hui; Liu, Xiao; Yu, Chang; Zheng, Hancheng; Jian, Min; Nie, Liping; Wan, Lei; Shi, Min; Sun, Xiaojuan; Tang, Aifa; Guo, Guangwu; Gui, Yaoting; Cai, Zhiming; Li, Jingxiang; Wang, Wen; Lu, Zuhong; Zhang, Xiuging; Bolund, Lars; Kristiansen, Karsten; Wang, Jian; Yang, Huanming; Dean, Michael; Wang, Jun.
In: GigaScience, Vol. 1, No. 12, 12.2012, p. 1-14.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Analyses of pig genomes provide insight into porcine demography and evolution. / Groenen, Martien A M; Archibald, Alan L; Uenishi, Hirohide; Tuggle, Christopher K; Takeuchi, Yasuhiro; Rothschild, Max F; Rogel-Gaillard, Claire; Park, Chankyu; Milan, Denis; Megens, Hendrik-Jan; Li, Shengting; Larkin, Denis M; Kim, Heebal; Frantz, Laurent A F; Caccamo, Mario; Ahn, Hyeonju; Aken, Bronwen L; Anselmo, Anna; Anthon, Christian; Auvil, Loretta; Badaoui, Bouabid; Beattie, Craig W; Bendixen, Christian; Berman, Daniel; Blecha, Frank; Blomberg, Jonas; Bolund, Lars; Bosse, Mirte; Botti, Sara; Zhan, Bujie; Bystrom, Megan; Capitanu, Boris; Carvalho-Silva, Denise; Chardon, Patrick; Chen, Celine; Cheng, Ryan; Choi, Sang-Haeng; Chow, William; Clark, Richard C; Clee, Christopher; Crooijmans, Richard P M A; Dawson, Harry D; Dehais, Patrice; De Sapio, Fioravante; Dibbits, Bert; Drou, Nizar; Du, Zhi-Qiang; Eversole, Kellye; Fadista, João; Fairley, Susan; Faraut, Thomas; Faulkner, Geoffrey J; Fowler, Katie E; Fredholm, Merete; Fritz, Eric; Gilbert, James G R; Giuffra, Elisabetta; Gorodkin, Jan; Griffin, Darren K; Harrow, Jennifer L; Hayward, Alexander; Howe, Kerstin; Hu, Zhi-Liang; Humphray, Sean J; Hunt, Toby; Hornshøj, Henrik; Jeon, Jin-Tae; Jern, Patric; Jones, Matthew; Jurka, Jerzy; Kanamori, Hiroyuki; Kapetanovic, Ronan; Kim, Jaebum; Kim, Jae-Hwan; Kim, Kyu-Won; Kim, Tae-Hun; Larson, Greger; Lee, Kyooyeol; Lee, Kyung-Tai; Leggett, Richard; Lewin, Harris A; Li, Yingrui; Liu, Wansheng; Loveland, Jane E; Lu, Yao; Lunney, Joan K; Ma, Jian; Madsen, Ole; Mann, Katherine; Matthews, Lucy; McLaren, Stuart; Morozumi, Takeya; Murtaugh, Michael P; Narayan, Jitendra; Nguyen, Dinh Truong; Ni, Peixiang; Oh, Song-Jung; Onteru, Suneel; Panitz, Frank; Park, Eung-Woo; Park, Hong-Seog; Pascal, Geraldine; Paudel, Yogesh; Perez-Enciso, Miguel; Ramirez-Gonzalez, Ricardo; Reecy, James M; Rodriguez-Zas, Sandra; Rohrer, Gary A; Rund, Lauretta; Sang, Yongming; Schachtschneider, Kyle; Schraiber, Joshua G; Schwartz, John; Scobie, Linda; Scott, Carol; Searle, Stephen; Servin, Bertrand; Southey, Bruce R; Sperber, Goran; Stadler, Peter; Sweedler, Jonathan V; Tafer, Hakim; Thomsen, Bo; Wali, Rashmi; Wang, Jian; Wang, Jun; White, Simon; Xu, Xun; Yerle, Martine; Zhang, Guojie; Zhang, Jianguo; Zhang, Jie; Zhao, Shuhong; Rogers, Jane; Churcher, Carol; Schook, Lawrence B.
In: Nature, Vol. 491, No. 7424, 15.11.2012, p. 393-398.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions. / Blechingberg, Jenny; Luo, Yonglun; Bolund, Lars; Damgaard, Christian Kroun; Nielsen, Anders Lade.
In: P L o S One, Vol. 7, No. 9, 25.09.2012, p. e46251.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Array comparative genomic hybridization of keratoacanthomas and squamous cell carcinomas : different patterns of genetic aberrations suggest two distinct entities. / Li, Jian; Wang, Kai; Gao, Fei; Jensen, Thomas D; Li, Shengting T; Deangelis, Paula M; Kølvraa, Steen; Proby, Charlotte; Forslund, Ola; Bolund, Lars; Clausen, Ole Petter F.
In: Journal of Investigative Dermatology, Vol. 132, No. 8, 2012, p. 2060-6.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin. / Staunstrup, Nicklas Heine; Madsen, Johannes Kjær; Primo, Maria Nascimento; Li, Juan; Liu, Ying; Kragh, Peter M; Li, Rong; Schmidt, Mette; Purup, Stig; Dagnæs-Hansen, Frederik; Svensson, Lars; Petersen, Thomas K; Callesen, Henrik; Bolund, Lars; Mikkelsen, Jacob Giehm.
In: P L o S One, Vol. 7, No. 5, 2012, p. e36658.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Genetic design of pigs as experimental models in the combat between chronic diseases and healthy aging. / Bolund, Lars.
In: Reproduction, Fertility and Development, Vol. 25, No. 1, 2012, p. 321.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Genetically modified pigs for biomedical research. / Luo, Yonglun; Lin, Lin; Bolund, Lars; Jensen, Thomas G; Sørensen, Charlotte Brandt.
In: Journal of Inherited Metabolic Disease, Vol. 35, No. 4, 2012, p. 695-713.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Handmade cloned transgenic piglets expressing the nematode fat-1 gene. / Zhang, Peng; Zhang, Yidi; Dou, Hongwei; Yin, Jingdong; Chen, Yu; Pang, Xinzhi; Vajta, Gabor; Bolund, Lars; Du, Yutao; Ma, Runlin Z.
In: Cellular Reprogramming, Vol. 14, No. 3, 2012, p. 258-66.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Hypercholesterolemic minipigs created by liver-specific expression of a PCSK9 gain-of-function mutant. / Bentzon, Jacob Fog; Sørensen, Charlotte Brandt; Al-Mashhadi, Rozh Husain; Kragh, Peter M; Nielsen, Lars Bo; Li, Juan; Lin, Lin; Liu, Ying; Moldt, Brian; Schmidt, Mette; Thim, Troels; Vajta, Gabor; Purup, Stig; Bolund, Lars; Callesen, Henrik; Mikkelsen, Jacob Giehm; Falk, Erling.
In: Transgenic Research, Vol. 21, No. 4, 2012, p. 910-911.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
Mosaic moles and non-familial biparental moles are not caused by mutations in NLRP7, NLRP2 or C6orf221. / Andreasen, L; Bolund, L; Niemann, I; Hansen, E S; Sunde, L.
In: Molecular Human Reproduction, Vol. 18, No. 12, 2012, p. 593-8.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences. / Luo, Yonglun; Bolund, Lars; Sørensen, Charlotte Brandt.
In: Transgenic Research, Vol. 21, 2012, p. 671-676.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. / Hou, Yong; Song, Luting; Zhu, Ping; Zhang, Bo; Tao, Ye; Xu, Xun; Li, Fuqiang; Wu, Kui; Liang, Jie; Shao, Di; Wu, Hanjie; Ye, Xiaofei; Ye, Chen; Wu, Renhua; Jian, Min; Chen, Yan; Xie, Wei; Zhang, Ruren; Chen, Lei; Liu, Xin; Yao, Xiaotian; Zheng, Hancheng; Yu, Chang; Li, Qibin; Gong, Zhuolin; Mao, Mao; Yang, Xu; Yang, Lin; Li, Jingxiang; Wang, Wen; Lu, Zuhong; Gu, Ning; Laurie, Goodman; Bolund, Lars; Kristiansen, Karsten; Wang, Jian; Yang, Huanming; Li, Yingrui; Zhang, Xiuqing; Wang, Jun.
In: Cell, Vol. 148, No. 5, 2012, p. 873-85.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. / Xu, Xun; Hou, Yong; Yin, Xuyang; Bao, Li; Tang, Aifa; Song, Luting; Li, Fuqiang; Tsang, Shirley; Wu, Kui; Wu, Hanjie; He, Weiming; Zeng, Liang; Xing, Manjie; Wu, Renhua; Jiang, Hui; Liu, Xiao; Cao, Dandan; Guo, Guangwu; Hu, Xueda; Gui, Yaoting; Li, Zesong; Xie, Wenyue; Sun, Xiaojuan; Shi, Min; Cai, Zhiming; Wang, Bin; Zhong, Meiming; Li, Jingxiang; Lu, Zuhong; Gu, Ning; Zhang, Xiuqing; Goodman, Laurie; Bolund, Lars; Wang, Jian; Yang, Huanming; Kristiansen, Karsten; Dean, Michael; Li, Yingrui; Wang, Jun.
In: Cell, Vol. 148, No. 5, 2012, p. 886-95.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Targeted Genome Editing by Recombinant Adeno-Associated Virus (rAAV) Vectors for Generating Genetically Modified Pigs. / Luo, Yonglun; Kofod-Olsen, Emil; Christensen, Rikke; Sørensen, Charlotte Brandt; Bolund, Lars.
In: Journal of Genetics and Genomics, Vol. 39, No. 6, 2012, p. 269-74.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Final Report Pigs and Health 2007-2011. / Bendixen, Christian; Callesen, Henrik; Bolund, Lars; Sørensen, Charlotte Brandt; Aarhus University: Department of Biomedicine & Department of Clinical Medicine; Aarhus University: Department of Molecular Biology and Genetics & Department of Animal Science; University of Copenhagen: Department of Basic Animal and Veterinary Sciences; Technical University of Denmark; LEO Pharma; Ellegaard Göttingen Minipigs A/S; Pixigene A/S; Pig Research Centre, Danish Agriculture and Food Council.
Højteknologifonden, 2011. 29 p.Research output: Book/anthology/dissertation/report › Report › Research
Mosaics and moles. / Sunde, Lone; Niemann, Isa; Hansen, Estrid Staehr; Hindkjaer, Johnny; Degn, Birte; Jensen, Uffe Birk; Bolund, Lars.
In: European Journal of Human Genetics, Vol. 19, No. 10, 08.06.2011, p. 1026-31.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Sequencing bias : Comparison of different protocols of MicroRNA library construction. / Tian, Geng; Gan, Shang Quang; Yin, Xu Yang; Luo, Hong; Xu, Xiao Hong; Bolund, Lars; Zhang, Xiu Qing; Li, Ning.
In: BMC Biotechnology, Vol. 11, 48, 11.05.2011.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate › Research › peer-review