Projects per year
Personal profile
Profile
I lead a translational research program in bladder cancer, focusing on the biological mechanisms of disease development, treatment response, and resistance. My group specializes in biomarker discovery and clinical implementation of liquid biopsy technologies, including ctDNA. We conduct prospective biobank studies and interventional trials aimed at developing and validating biomarkers to guide treatment decisions.
Job responsibilities
As Chair Professor (ledende professor), I am responsible for research at MOMA and lead a multidisciplinary group in translational bladder cancer research. I am part of the department’s leadership and oversee daily research management, supervision of junior researchers, and project development in collaboration with clinical and international partners. I serve as PI on national clinical trials and as vice-director of the DCCC ctDNA Center.
Keywords
- Cancer
- Cancer
- Kidneys and urinary tract
- Bioinformatics
- microarray data
- Genetics
Areas of expertise
- cancer research
- bio markers
- bladder cancer
- circulating tumor DNA
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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PhD project: GreenBladder: Early detection of bladder cancer in residents in Greenland using a urinary marker and a mobile cystoscopy unit
Fryd, N. D. (PI), Jensen, J. B. (PI), Ernst, A. (Participant), Bernth-Andersen, S. O. (Participant) & Dyrskjøt, L. (Participant)
01/04/2023 → 01/03/2026
Project: Research
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DaVulvaRec: Danish Vulva Cancer Recurrence Study
Krog, L. (PI), Fuglsang, K. (Participant), Dyrskjøt, L. (Participant), Paskeviciute Frøding, L. (Participant), Schnack, T. H. (Participant), Grønvold, M. (Participant), Waldstrøm, M. (Participant), Strøm Kahr, H. (Participant), Christensen, P. (Participant), Wulff, C. (Participant), Kristoffersen, K. B. (Participant), Lindved, S. B. (Participant) & Jensen, P. T. (Project manager)
01/02/2023 → …
Project: Research
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The urinary microbiome
Birkenkamp-Demtröder, K. (PI), Gøttler, J. (Participant), Nordentoft, I. K. (Participant) & Dyrskjøt, L. (PI)
01/09/2022 → …
Project: Research
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TOMBOLA: Treatment Of Metastatic Bladder cancer at the time Of biochemical reLApse following radical cystectomy
Birkenkamp-Demtröder, K. (PI), Nordentoft, I. K. (Collaborator), Agerbæk, M. (PI), Jensen, J. B. (PI) & Dyrskjøt, L. (PI)
01/04/2020 → …
Project: Research
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Individualiseret kræft monitorering vha. dyb sekventering af cirkulerende tumor DNA i patienter med avanceret blærekræft
Birkenkamp-Demtröder, K. (Participant), Dyrskjøt, L. (Participant), Jensen, J. B. (Participant) & Agerbæk, M. (Participant)
01/07/2017 → …
Project: Research
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Bladder cancer
Dyrskjøt, L., Hansel, D. E., Efstathiou, J. A., Knowles, M. A., Galsky, M. D., Teoh, J. & Theodorescu, D., Oct 2023, In: Nature Reviews Disease primers. 9, 1, 58.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Open Access281 Citations (Scopus) -
Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma
Christensen, E., Birkenkamp-Demtröder, K., Sethi, H., Shchegrova, S., Salari, R., Nordentoft, I., Wu, H.-T., Knudsen, M., Lamy, P., Lindskrog, S. V., Taber, A., Balcioglu, M., Vang, S., Assaf, Z., Sharma, S., Tin, A. S., Srinivasan, R., Hafez, D., Reinert, T. & Navarro, S. & 14 others, , Jun 2019, In: Journal of Clinical Oncology. 37, 18, p. 1547-1557 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile407 Citations (Scopus)280 Downloads (Pure) -
Molecular correlates of cisplatin-based chemotherapy response in muscle invasive bladder cancer by integrated multi-omics analysis
Taber, A., Christensen, E., Lamy, P., Nordentoft, I., Prip, F., Lindskrog, S. V., Birkenkamp-Demtröder, K., Okholm, T. L. H., Knudsen, M., Pedersen, J. S., Steiniche, T., Agerbæk, M., Jensen, J. B. & Dyrskjøt, L., Sept 2020, In: Nature Communications. 11, 1, 15 p., 4858.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access157 Citations (Scopus) -
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
Lindskrog, S. V., Prip, F., Lamy, P., Taber, A., Groeneveld, C. S., Birkenkamp-Demtröder, K., Jensen, J. B., Strandgaard, T., Nordentoft, I., Christensen, E., Sokac, M., Birkbak, N. J., Maretty, L., Hermann, G. G., Petersen, A. C., Weyerer, V., Grimm, M. O., Horstmann, M., Sjödahl, G. & Höglund, M. & 27 others, , 1 Dec 2021, In: Nature Communications. 12, 1, 18 p., 2301.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access245 Citations (Scopus) -
Field Cancerization Is Associated with Tumor Development, T-cell Exhaustion, and Clinical Outcomes in Bladder Cancer
Strandgaard, T., Nordentoft, I., Birkenkamp-Demtröder, K., Salminen, L., Prip, F., Rasmussen, J., Andreasen, T. G., Lindskrog, S. V., Christensen, E., Lamy, P., Knudsen, M., Steiniche, T., Jensen, J. B. & Dyrskjøt, L., Jan 2024, In: European Urology. 85, 1, p. 82-92 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile33 Citations (Scopus)119 Downloads (Pure)
Activities
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Board member, Scientific Congress Office (SCO) at European Association of Urology
Dyrskjøt, L. (Participant)
2020 → …Activity: Presentations, memberships, employment, ownership and other activities › Other
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Board Member, EAU Section of Urological Research (ESUR)
Dyrskjøt, L. (Participant)
2022 → …Activity: Presentations, memberships, employment, ownership and other activities › Other
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Videnskabeligt udvalg i Dansk Kræftforskningsfond
Dyrskjøt, L. (Member)
2019 → 2023Activity: Presentations, memberships, employment, ownership and other activities › Member of board or management of company or organisation
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Statens Serum Institut
Dyrskjøt, L. (Member)
Jul 2024 → …Activity: Presentations, memberships, employment, ownership and other activities › Member of committee, council or board
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Bio- and Genome Bank Denmark
Dyrskjøt, L. (Member)
Jun 2024 → …Activity: Presentations, memberships, employment, ownership and other activities › Member of committee, council or board
Prizes
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Modtager af Kræftens Bekæmpelses Juniorforskerpris
Dyrskjøt, L. (Recipient), 2011
Prize: Prizes, scholarships, distinctions
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Pris for mest publicerende forsker under 40 på Aarhus Universitetshospital
Dyrskjøt, L. (Recipient), 2009
Prize: Prizes, scholarships, distinctions
Press/Media
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Danske forskere bremser dødelig blærekræft i mus
20/04/2017
1 Media contribution
Press/Media: Press / Media
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