Kristian Stengaard-Pedersen

Insulin-like growth factor I receptor density on CD4+T-lymphocytes from active early steroid- and DMARD-naïve rheumatoid arthritis patients is up-regulated and not influenced by 1 year of clinically effective treatment

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Insulin-like growth factor I receptor density on CD4+T-lymphocytes from active early steroid- and DMARD-naïve rheumatoid arthritis patients is up-regulated and not influenced by 1 year of clinically effective treatment. / Laurberg, Trine Bay; Ellingsen, Torkell; Thorsen, Jonas; Møller, Bjarne Kuno; Hansen, Ib; Tarp, Ulrik; Hetland, Merete Lund; Hørslev-Petersen, Kim; Flyvbjerg, Allan; Frystyk, Jan; Stengaard-Pedersen, Kristian.

In: Rheumatology International, Vol. 32, No. 2, 19.01.2012, p. 501.

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@article{ccaedadc0f9e47e7a69642552ae42a70,
title = "Insulin-like growth factor I receptor density on CD4+T-lymphocytes from active early steroid- and DMARD-na{\"i}ve rheumatoid arthritis patients is up-regulated and not influenced by 1 year of clinically effective treatment",
abstract = "The IGF-IR density on CD4+T-lymphocytes was studied using flow cytometry in 40 early steroid- and DMARD-na{\"i}ve rheumatoid arthritis (RA) patients before and after 52 weeks of treatment with methotrexate+placebo or methotrexate+cyclosporine A and in 15 controls. RA patients had increased IGF-IR density on CD4+T-lymphocytes at week 0 and week 52, irrespective of treatment. IGF-IR-positive CD4+T-lymphocytes fraction decreased during treatment, but neither at week 0 nor at week 52 did it differ from healthy controls. No correlations were found to disease activity parameters.",
author = "Laurberg, {Trine Bay} and Torkell Ellingsen and Jonas Thorsen and M{\o}ller, {Bjarne Kuno} and Ib Hansen and Ulrik Tarp and Hetland, {Merete Lund} and Kim H{\o}rslev-Petersen and Allan Flyvbjerg and Jan Frystyk and Kristian Stengaard-Pedersen",
year = "2012",
month = "1",
day = "19",
doi = "10.1007/s00296-010-1683-z",
language = "English",
volume = "32",
pages = "501",
journal = "Rheumatology International",
issn = "0172-8172",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Insulin-like growth factor I receptor density on CD4+T-lymphocytes from active early steroid- and DMARD-naïve rheumatoid arthritis patients is up-regulated and not influenced by 1 year of clinically effective treatment

AU - Laurberg, Trine Bay

AU - Ellingsen, Torkell

AU - Thorsen, Jonas

AU - Møller, Bjarne Kuno

AU - Hansen, Ib

AU - Tarp, Ulrik

AU - Hetland, Merete Lund

AU - Hørslev-Petersen, Kim

AU - Flyvbjerg, Allan

AU - Frystyk, Jan

AU - Stengaard-Pedersen, Kristian

PY - 2012/1/19

Y1 - 2012/1/19

N2 - The IGF-IR density on CD4+T-lymphocytes was studied using flow cytometry in 40 early steroid- and DMARD-naïve rheumatoid arthritis (RA) patients before and after 52 weeks of treatment with methotrexate+placebo or methotrexate+cyclosporine A and in 15 controls. RA patients had increased IGF-IR density on CD4+T-lymphocytes at week 0 and week 52, irrespective of treatment. IGF-IR-positive CD4+T-lymphocytes fraction decreased during treatment, but neither at week 0 nor at week 52 did it differ from healthy controls. No correlations were found to disease activity parameters.

AB - The IGF-IR density on CD4+T-lymphocytes was studied using flow cytometry in 40 early steroid- and DMARD-naïve rheumatoid arthritis (RA) patients before and after 52 weeks of treatment with methotrexate+placebo or methotrexate+cyclosporine A and in 15 controls. RA patients had increased IGF-IR density on CD4+T-lymphocytes at week 0 and week 52, irrespective of treatment. IGF-IR-positive CD4+T-lymphocytes fraction decreased during treatment, but neither at week 0 nor at week 52 did it differ from healthy controls. No correlations were found to disease activity parameters.

U2 - 10.1007/s00296-010-1683-z

DO - 10.1007/s00296-010-1683-z

M3 - Journal article

C2 - 21246373

VL - 32

SP - 501

JO - Rheumatology International

JF - Rheumatology International

SN - 0172-8172

IS - 2

ER -