Kasper Thorsen

  1. 2021
  2. Published

    Exploring associations between constipation, severity of neurofibromatosis type 1 and NF1 mutational spectrum. / Ejerskov, Cecilie; Gaustadnes, Mette; Ostergaard, John R.; Krogh, Klaus; Thorsen, Kasper; Borglum, Anders D.; Haagerup, Annette.

    In: Scientific Reports, Vol. 11, 9179, 12.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2018
  4. Published

    Genetic analysis of Charcot-Marie-Tooth disease in Denmark and the implementation of a next generation sequencing platform. / Væth, Signe; Christensen, Rikke; Dunø, Morten; Lildballe, Dorte Launholt; Thorsen, Kasper; Vissing, John; Svenstrup, Kirsten; Hertz, Jens Michael; Andersen, Henning; Jensen, Uffe Birk.

    In: European Journal of Medical Genetics, 11.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    A Rare Case of Embryonal Carcinoma in a Patient with Turner Syndrome without Y Chromosomal Material but Mutations in KIT, AKT1, and ZNF358 Demonstrated Using Exome Sequencing. / Gravholt, Claus H; Dollerup, Ole L; Duval, Lone; Mejlgaard, Else; Stribolt, Katrine; Vang, Søren; Laursen, Britt E; Knudsen, Michael; Thorsen, Kasper; Hersmus, Remko; Looijenga, Leendert H J; Stochholm, Kirstine.

    In: Sexual Development, Vol. 11, No. 5-6, 2018, p. 262-268.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2017
  7. Published

    Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome. / Thorsen, Kasper; Dam, Vibeke S.; Kjaer-Sorensen, Kasper; Pedersen, Lisbeth N.; Skeberdis, V. Arvydas; Jurevičius, Jonas; Treinys, Rimantas; Petersen, Ida M.B.S.; Nielsen, Morten S.; Oxvig, Claus; Morth, J. Preben; Matchkov, Vladimir V.; Aalkjær, Christian; Bundgaard, Henning; Jensen, Henrik K.

    In: Nature Communications, Vol. 8, No. 1, 1696, 01.12.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Enrichment of Genetic Variants in the Glucocorticoid Receptor Signalling Pathway in Autoimmune Hepatitis with Failure of Standard Treatment. / Eriksen, Peter Lykke; Kreutzfeldt, Martin; Grønbaek, Henning; Thorsen, Kasper; Vang, Søren; Jessen, Niels; Vilstrup, Hendrik.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 121, No. 3, 09.2017, p. 189-194.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. / Møller, Andreas Buch; Kampmann, Ulla; Hedegaard, Jakob; Thorsen, Kasper; Nordentoft, Iver; Vendelbo, Mikkel Holm; Møller, Niels; Jessen, Niels.

    In: Scientific Reports, Vol. 7, 43775, 02.03.2017, p. 1-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2015
  11. Published

    AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice. / Fentz, Joachim; Kjøbsted, Rasmus; Birk, Jesper B.; Jordy, Andreas B.; Jeppesen, Jacob; Thorsen, Kasper; Schjerling, Peter; Kiens, Bente; Jessen, Niels; Viollet, Benoit; Wojtaszewski, Jørgen F P.

    In: F A S E B Journal, Vol. 29, No. 5, 01.05.2015, p. 1725-1738.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. / Kjær, Thomas Nordstrøm; Thorsen, Kasper; Jessen, Niels; Stenderup, Karin; Pedersen, Steen Bønløkke.

    In: PLOS ONE, Vol. 10, No. 5, e0126599, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. 2014
  14. Published

    Mutational context and diverse clonal development in early and late bladder cancer : Genomic changes in bladder cancer. / Nordentoft, Iver Kristiansen; Lamy, Philippe; Birkenkamp-Demtröder, Karin; Shumansky, Karey ; Vang, Søren; Hornshøj, Henrik; Juul, Malene ; Villesen, Palle; Hedegaard, Jakob; Roth, Andrew; Thorsen, Kasper; Høyer, Søren; Borre, Michael; Reinert, Thomas; Fristrup, Niels; Dyrskjøt, Lars; Shah, Sohrab; Pedersen, Jakob Skou; Ørntoft, Torben Falck.

    In: Cell Reports, Vol. 7, No. 5, 12.06.2014, p. 1649–1663.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Charcot-Marie-Tooth disease: The development of a diagnostic platform using next generation sequencing. / Christensen, Rikke; Væth, Signe; Thorsen, Kasper; Rikke, Kristiansen; Dunø, Morten; Jensen, Uffe Birk.

    2014. Poster session presented at Next Generation Sequencing Data Congress, London, United Kingdom.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Mnk2 alternative splicing modulates the p38-MAPK pathway and impacts Ras-induced transformation. / Maimon, Avraham; Mogilevsky, Maxim; Shilo, Asaf; Golan-Gerstl, Regina; Obiedat, Akram; Ben-Hur, Vered; Lebenthal-Loinger, Ilana; Stein, Ilan; Reich, Reuven; Beenstock, Jonah; Zehorai, Eldar; Andersen, Claus Lindbjerg; Thorsen, Kasper; Orntoft, Torben F; Davis, Roger J; Davidson, Ben; Mu, David; Karni, Rotem.

    In: Cell Reports, Vol. 7, No. 2, 24.04.2014, p. 501-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Hypermethylation of the GABRE~miR-452~miR-224 Promoter in Prostate Cancer Predicts Biochemical Recurrence after Radical Prostatectomy. / Kristensen, Helle; Haldrup, Christa; Strand, Siri; Mundbjerg, Kamilla; Mortensen, Martin M; Thorsen, Kasper; Ostenfeld, Marie Stampe; Wild, Peter J; Arsov, Christian; Goering, Wolfgang; Visakorpi, Tapio; Egevad, Lars; Lindberg, Johan; Grönberg, Henrik; Høyer, Søren; Borre, Michael; Orntoft, Torben F; Sørensen, Karina Dalsgaard.

    In: Clinical Cancer Research, Vol. 20, No. 8, 15.04.2014, p. 2169-81.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Genome and RNA sequencing identifies fusion transcripts in bladder cancer. / Nordentoft, Iver Kristiansen; Birkenkamp-Demtröder, Karin; Lamy, Philippe; Reinert, Thomas; Vang, Søren; Hedegaard, Jakob; Thorsen, Kasper; Dyrskjøt, Lars; Pedersen, Jakob Skou; Ørntoft, Torben Falck.

    2014. Abstract from AACR Annual Meeting 2014, San Diego, California, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  19. Published

    The toxic effects of single-walled carbon nanotubes are linked to the phagocytic ability of cells. / Foldbjerg, Rasmus; Irving, Eveline S; Wang, Jing; Thorsen, Kasper; Sutherland, Duncan S; Autrup, Herman; Beer, Christiane.

    In: Toxicology Research, Vol. 3, 2014, p. 228-241.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2013
  21. Published

    Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells : KRT23 in human colon cancer . / Birkenkamp-Demtröder, Karin; Hahn, Stephan; Mansilla, Francisco; Thorsen, Kasper; Maghnouj, Abdelouahid ; Christensen, Rikke; Øster, Bodil; Ørntoft, Torben Falck.

    In: P L o S One, Vol. 8, No. 9, 09.09.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer. / Christensen, Lise Lotte; Tobiasen, Heidi; Holm, Anja; Schepeler, Troels; Ostenfeld, Marie Stampe; Thorsen, Kasper; Rasmussen, Mads Heilskov; Birkenkamp-Demtröder, Karin; Sieber, Oliver M; Gibbs, Peter; Lubinski, Jan; Lamy, Philippe; Laurberg, Søren; Øster, Bodil; Hansen, Kristian Qvist; Hagemann-Madsen, Rikke; Byskov, Kristina; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: International Journal of Cancer, Vol. 133, No. 1, 07.2013, p. 67-78.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Whole genome and transcriptome analysis reveals novel genomic alterations in bladder cancer. / Nordentoft, Iver Kristiansen; Lamy, Philippe; Birkenkamp-Demtröder, Karin; Vang, Søren; Reinert, Thomas; Hedegaard, Jakob; Thorsen, Kasper; Fristrup, Niels; Borre, Michael; Andersen, Lars Dyrskjøt; Pedersen, Jakob Skou; Ørntoft, Torben Falck.

    2013. Poster session presented at American Association for Cancer Research, Washington, DC, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  24. Published

    The splicing factor SRSF6 is amplified and is an oncoprotein in lung and colon cancers. / Cohen-Eliav, Michal; Golan-Gerstl, Regina; Siegfried, Zahava; Andersen, Claus L; Thorsen, Kasper; Orntoft, Torben F; Mu, David; Karni, Rotem.

    In: Journal of Pathology, Vol. 229, No. 4, 03.2013, p. 630-639.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    TOX3 (TNRC9) overexpression in bladder cancer cells decreases cellular proliferation and triggers an interferon-like response. / Birkenkamp-Demtröder, Karin; Mansilla, Francisco; Andersen, Lars Dyrskjøt; Thorsen, Kasper; Fristrup, Niels; Brems-Eskildsen, Anne Sofie; Madsen, Pia Pinholt; Sørensen, Karina Dalsgaard; Borre, Michael; Ørntoft, Torben Falck.

    In: Journal of Molecular Biomarkers & Diagnosis, Vol. 4, No. 1, 01.2013, p. 1-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Functional screening identifies miRNAs that induce apoptosis and/or inhibit proliferation in colorectal cancer. / Christensen, Lise Lotte; Holm, Anja; Schepeler, Troels; Rantala, Juha ; Kallioniemi, Olli; Thorsen, Kasper; Rasmussen, Mads Heilskov; Birkenkamp-Demtröder, Karin; Sieber, Oliver M; Gibbs, Peter; Lamy, Philippe; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    2013. Poster session presented at Keystone Symposium, Vancouver, Canada.

    Research output: Contribution to conferencePosterResearchpeer-review

  27. 2012
  28. Published

    Global gene expression profiling of human lung epithelial cells after exposure to nanosilver. / Foldbjerg, Rasmus; Irving, Eveline S; Hayashi, Yuya; Sutherland, Duncan; Thorsen, Kasper; Autrup, Herman; Beer, Christiane.

    In: Toxicological Sciences, Vol. 130, No. 1, 11.2012, p. 145-157.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes. / Schepeler, Troels; Holm, Anja; Halvey, P; Nordentoft, Iver Kristiansen; Lamy, Philippe; Riising, Eva Madi; Christensen, Lise Lotte; Thorsen, Kasper; Liebler, D C; Helin, Kristian; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: Oncogene, 31.05.2012, p. 2750-2760.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    AACR Annual meeting, Chicago, USA: Secreted exosomes from cultured bladder cancer cells are enriched for distinct miRNAs detected in circulation of metastatic bladder cancer patients. / Ostenfeld, Marie Stampe; Jeppesen, Dennis Kjølhede; Morth, Jens Preben; Bui, Khan H; Thorsen, Kasper; Theodorescu, Dan; Borre, Michael; Dyrskjøt, Lars; Ørntoft, Torben Falck.

    2012.

    Research output: Contribution to conferencePosterResearch

  31. Published

    Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways. / Dallosso, A R; Øster, Bodil; Greenhough, A; Thorsen, Kasper; Curry, T J; Owen, C; Hancock, A L; Szemes, M; Paraskeva, C; Frank, M; Andersen, Claus Lindbjerg; Malik, K.

    In: Oncogene, No. 31, 2012, p. 4409-4419.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer. / Oster, Bodil; Linnet, Lene; Christensen, Lise Lotte; Thorsen, Kasper; Ongen, Halit; Dermitzakis, Emmanouil T; Sandoval, Juan; Moran, Sebastian; Esteller, Manel; Hansen, Torben Frøstrup; Lamy, Philippe; Laurberg, Søren; Orntoft, Torben F; Andersen, Claus Lindbjerg.

    In: International Journal of Cancer, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. 2011
  34. Published

    Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis. / Thorsen, Kasper; Schepeler, Troels; Øster, Bodil; Rasmussen, Mads H; Vang, Soren; Wang, Kai; Hansen, Kristian Q; Lamy, Philippe; Pedersen, Jakob Skou; Eller, Asger Østerberg; Mansilla, Francisco; Laurila, Kirsti; Wiuf, Carsten Henrik; Laurberg, Soren; Dyrskjot, Lars; Orntoft, Torben F; Andersen, Claus L.

    In: B M C Genomics, Vol. 12, No. 1, 14.10.2011, p. 505.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published
  36. Published

    Identification of miRNAs associated with recurrence of stage II colorectal cancer. / Christensen, Lise Lotte; Tobiasen, Heidi; Schepeler, Troels; Thorsen, Kasper; Birkenkamp-Demtröder, Karin; Lubinski, Jan; Sieber, Oliver M; Lamy, Philippe; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    2011. Poster session presented at MicroRNAs and Non-coding RNAs and Cancer, Canada.

    Research output: Contribution to conferencePosterResearchpeer-review

  37. Published

    Repression of KIAA1199 attenuates wnt-signalling and decreases the proliferation of colon cancer cells : KIAA1199 in colorectal cancer. / Birkenkamp-Demtröder, Karin; Maghnouj, Abdelouahid; Mansilla, Francisco; Thorsen, Kasper; Øster, Bodil; Andersen, Claus Lindbjerg; Hahn, Stephan; Ørntoft, Torben Falck.

    In: British Journal of Cancer, 2011.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2010
  39. Published

    Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer. / Andersen, Claus Lindbjerg; Lamy, Philippe; Thorsen, Kasper; Kjeldsen, Eigil; Wikman, Friedrik; Villesen, Palle; Øster, Bodil; Laurberg, Søren; Ørntoft, Torben Falck.

    In: International Journal of Cancer, 10.12.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    KIAA1199 depletion targets the wnt/beta catenin signaling pathway and impairs migration and proliferation of human colon cancer cells . / Birkenkamp-Demtröder, Karin; Maghnouj, Abdelouahid ; Mansilla, Francisco; Thorsen, Kasper; Andersen, Claus Lindbjerg; Øster, Bodil; Hahn, Stephan; Ørntoft, Torben Falck.

    2010. Abstract from 101th Annual Meeting of the American Association of Cancer Research (AACR), Washington, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  41. Published

    Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway. / Thorsen, Kasper; Mansilla, Francisco; Schepler, Troels; Øster, Bodil; Rasmussen, Mads Heilskov; Andersen, Lars Dyrskjøt; Karni, Rotem; Akerman, Martin; Krainer, Adrian R; Laurberg, Søren; Andersen, Claus Lindbjerg; Ørntoft, Torben Falck.

    In: Molecular and Cellular Proteomics, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells. / Ortis, Fernanda; Naamane, Najib; Flamez, Daisy; Ladrière, Laurence; Moore, Fabrice; Cunha, Daniel A.; Colli, Maikel L.; Thykjaer, Thomas; Thorsen, Kasper; Ørntoft, Torben Falck; Eizirik, Decio L.

    In: Diabetes, Vol. 59, No. 2, 2010, p. 358-374.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. 2009
  44. Published

    DNA microarrays and genetic testing. / Andersen, Lars Dyrskjøt; Sørensen, Karina Dalsgaard; Ostenfeld, Marie Stampe; Thorsen, Kasper; Tørring, Niels; Andersen, Claus Lindbjerg; Birkenkamp-Demtröder, Karin; Kruhøffer, Mogens; Ørntoft, Torben Falck.

    Molecular Diagnostics. 2009.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  45. Published

    Downstream targets of SMARCC1, a transcription regulator deregulated in colorectal cancer. / Jensen, Hanne Bak; Mansilla, Francisco; Thorsen, Kasper; Ørntoft, Torben Falck; Birkenkamp-Demtröder, Karin.

    2009. Abstract from   1ooth Annual Meeting of the American Association of Cancer Research (AACR), Denver, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  46. Published

    Dysregulation of the transcription factors SOX4, CBFB, and SMARCC1 correlates with outcome of colorectal cancer. / Andersen, Claus Lindbjerg; Christensen, Lise Lotte; Thorsen, Kasper; Schepeler, Troels; Sørensen, Flemming Brandt; Verspaget, Hein W.; Simon, Ronald; Kruhøffer, Mogens; Aaltonen, Lauri A.; Laurberg, Søren; Ørntoft, Torben Falck.

    In: British Journal of Cancer, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Transcription regulator SMARCC1 is deregulated in colorectal cancer. Implications for the SWI/SNF complex and other down-stream targets. / Mansilla, Francisco; Jensen, Hanne Bak; Thorsen, Kasper; Ørntoft, Torben Falck; Birkenkamp-Demtröder, Karin.

    2009. Poster session presented at 46. CANCER PROTEOMICS CONFERENCE, Mechanistic Insights, Technological Advances & Molecular Medicine, Dublin, Ireland.

    Research output: Contribution to conferencePosterResearch

  48. 2008
  49. Published

    Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis. / Thorsen, Kasper; Sørensen, Karina D; Brems-Eskildsen, Anne Sofie; Modin, Charlotte; Gaustadnes, Mette; Hein, Anne-Mette K; Kruhøffer, Mogens; Laurberg, Søren; Borre, Michael; Wang, Kai; Brunak, Søren; Krainer, Adrian R; Tørring, Niels; Dyrskjøt, Lars; Andersen, Claus L; Ørntoft, Torben Falck.

    In: Molecular and Cellular Proteomics, Vol. 7, No. 7, 2008, p. 1214-24.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. 2007
  51. Published

    Clusterin expression in normal mucosa and colorectal cancer. / Andersen, Claus Lindbjerg; Schepeler, Troels; Thorsen, Kasper; Birkenkamp-Demtröder, Karin; Mansilla, Francisco; Aaltonen, Lauri A.; Laurberg, Søren; Ørntoft, Torben Falck.

    In: Molecular and Cellular Proteomics, Vol. 6, No. 6, 2007, p. 1039-1048.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review