Jørgen Frøkiær

Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

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  • Munsoor A. Hanifa, Department of Chemistry and Bioscience, Aalborg University, Department of Anaesthesia and Intensive Care, Danish Center for Clinical Health Services Research
  • ,
  • Martin Skott
  • Raluca G. Maltesen, Department of Anaesthesia and Intensive Care, Aalborg University
  • ,
  • Bodil S. Rasmussen, Department of Anaesthesia and Intensive Care, Aalborg University, Danish Center for Clinical Health Services Research
  • ,
  • Søren Nielsen, 2A Pharma AB
  • ,
  • Jørgen Frøkiær
  • Troels Ring, University of Pittsburgh
  • ,
  • Reinhard Wimmer, Aalborg University

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have been reported elsewhere (https://doi.org/10.1007/s11306-019-1569-3 [1]). The data could be useful to researchers working with human CKD or rat models of the disease. In addition, several different types of NMR spectra were recorded, including 1D NOESY, CPMG, and 2D J-resolved spectra, and the data could be useful for method comparison and algorithm development, both in terms of NMR spectroscopy and multivariate analysis.

Original languageEnglish
Article number106567
JournalData in Brief
Volume33
ISSN2352-3409
DOIs
Publication statusPublished - Dec 2020

Bibliographical note

Publisher Copyright:
© 2020 The Authors

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

    Research areas

  • 5/6 Nephrectomy, Chronic kidney disease, Metabolomics, NMR, Rat

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