Aarhus University Seal / Aarhus Universitets segl

Jørgen Frøkiær

Melamine-Related Urinary Stones in 195 Infants and Young Children: Clinical Features within 2 Years of Follow-Up

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Jian Guo Wen, Klinisk Medicin
  • ,
  • Qing Long Chang
  • ,
  • An Feng Lou
  • ,
  • Zhen Zhen Li
  • ,
  • Shan Lu
  • ,
  • Yan Wang
  • ,
  • Ya Lun Wang
  • ,
  • Jin Hua Hu
  • ,
  • Shu Ping Mao
  • ,
  • Yan Zhang
  • ,
  • Rui Xue
  • ,
  • Chuanchuan Ren
  • ,
  • Lu Xing
  • ,
  • Guo Xian Zhang
  • ,
  • Shengjun Zhang
  • ,
  • Jens Christian Djurhuus
  • Jørgen Frøkiaer
Objective: To summarize the clinical features and follow-up, the effects of melamine-tainted milk powder (MMP) consumption on kidney and body growth in children who suffered from melamine-related urinary stones (MUS) 2 years earlier were checked. Measurements: Body height and weight, kidney and bladder morphology monitored by ultrasound, urinalysis and renal function were recorded. Plain abdominal radiography was performed for differential diagnosis. The first follow-up was carried out at 15 months and the second 2 years later for patients who showed any abnormality at the first follow-up. Two hundred age- and gender-matched cohorts were included. Results: All cases received conservative treatment in hospital. Fifteen months of follow-up was successfully carried out in 167 cases. 91 children had residual MUS at the time of discharge, 58 MUS disappeared completely, 25 dissolved partially, 1 increased in size, and 7 did not change. At 2 years of follow-up, the residual stones all disappeared except for 1 case; the patient who showed a delayed development with regard to height caught up at 24 months of follow-up. Conclusions: Conservative treatment shows a high effectiveness in cases with residual MUS. Consumption of MMP with timely treatment did not demonstrate an evident impact on kidney and bladder although body height is slightly affected in a few cases.
Original languageEnglish
JournalUrologia Internationalis
ISSN0042-1138
DOIs
Publication statusPublished - 2011

See relations at Aarhus University Citationformats

ID: 41569026