Jørgen Frøkiær

  1. 2008
  2. Published

    How accurate is dynamic contrast-enchanced MRI in the assessment of Renal Glomerular Filtration Rate? A critical appraisal. / Mendichovszky, I; Pedersen, Michael; Frøkiær, Jørgen; Dissing, Thomas Heide; Greiner, N; Anderson, P; McHugh, K; Yang, Q; Gordon, Isky.

    In: Journal of Magnetic Resonance Imaging, Vol. 4, 2008, p. 925-931.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    MR Measurement of Glomerular filration rate: Principles, Limiations and Expectations. / Greiner, N; Mendichovszky, I; de Seneville, BD; Desbarat, P; Pedersen, Michael; Frøkiær, Jørgen; Gordon, Isky.

    In: Clinical Nuclear Medicine, Vol. 38, No. 1, 2008, p. 47-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Measurement of glomerular filtration rate with magnetic resonance imaging: principles, limitations, and expectations. / Grenier, Nicolas; Mendichovszky, Iosif; de Senneville, Baudouin Denis; Roujol, Sébastien; Desbarats, Pascal; Pedersen, Michael; Wells, Kevin; Frøkiær, Jørgen; Gordon, Isky.

    In: Seminars in Nuclear Medicine, Vol. 38, No. 1, 2008, p. 47-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Normal differential renal function does not indicate a normal kidney after partial ureteropelvic obstruction and subsequent relief in 2-week-old piglets. / Dissing, Thomas; Eskild-Jensen, Anni; Mikkelsen, Mette; Pedersen, Michael; Frøkiær, Jørgen; Djurhuus, Jens; Gordon, Isky.

    In: European Journal of Nuclear Medicine and Molecular Imaging, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Pathophysiology of urinary tract obstruction: Treatment of ureteral stone colics. / Jensen, Anja Møller; Stødkilde-Jørgensen, Lene; Nørregaard, Rikke; Madsen, Mia Gebauer; Frøkiær, Jørgen.

    In; Aspects of pharmacology of the pyeloureter with clinical perspectives.. Vol. 15 Mortensen J, Andreasen F, Simonsen U, 2008. p. 193.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  7. Published

    Predicting GFR in children aged 2 - 14 years based on serum cystatin C and bodycell mass. / Andersen, Trine Borup; Brøchner-Mortensen, Jens; Eskild-Jensen, Anni; Arveschoug, Anne Kirstine; Rittig, Søren; Erlandsen, Erland; Frøkiær, Jørgen.

    2008. Poster session presented at Forskningens Dag 2007, Aalborg, Denmark.

    Research output: Contribution to conferencePosterResearch

  8. Published

    Reduction of ischemic stroke in rat brain by alpha melanocyte stimulating hormone. / Chen, Gang; Frøkiær, Jørgen; Pedersen, Michael; Nielsen, Søren; Si, Zhichao; Pang, Qi; Stødkilde-Jørgensen, Hans.

    In: Neuropeptides, Vol. 42, No. 3, 2008, p. 331-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Regulation of AQP4 protein expression in rat brain astrocytes: Role of P2X7 receptor activation. / Lee, M; Lee, SJ; Choi, HJ; Hybg, YW; Frøkiær, Jørgen; Nielsen, Søren; Kwon, TH.

    In: Brain Research, Vol. 1195, No. 1, 2008, p. 1-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Reproducibility and repeatability of differential renal function in 4-week-old piglets. / Dissing, Thomas H; Eskild-Jensen, Anni; Pedersen, Michael; Anderson, Peter J; Rittig, Nikolaj; Frøkiaer, Jørgen; Gordon, Isky.

    In: Nuclear Medicine Communications, Vol. 29, No. 1, 2008, p. 76-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    The influence of high and low levels of estrogen on diurnal urine regulation in young women. / Graugaard-Jensen, Charlotte; Hvistendahl, Gitte M; Frøkiær, Jørgen; Bie, Peter; Djurhuus, Jens Christian.

    In: B M C Urology, Vol. 8, 2008, p. 16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    The little difference in urine production. / Graugaard-Jensen, Charlotte; Hvistendahl, Gitte M.; Frøkiær, Jørgen; Djurhuus, Jens Christian.

    2008. Poster session presented at PhD Day 2008, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  13. Published

    Ureter obstruction alters expression of renal acid-base transport proteins in rat kidney. / Wang, Guixian; Li, Chunling; Kim, SW; Ring, Troels; Wen, J; Djurhuus, Jens Christian; Wang, W; Nielsen, Søren; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, Vol. 295, No. 2, 2008, p. 497-506.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Urinary tract obstruction. / Frøkiær, Jørgen; Zeidel, ML.

    Brenner and Rectors, The Kidney, ed. BM Brenner 8th  Edition. 8. ed. W. B. Saunders Company, 2008. p. 1239-1264.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  15. Published

     A novel method of ligand peptidomics to identify peptide ligands binding to AQP2-expressing plasma membranes and intracellular vesicles of rat kidney.  . / Lee, YJ; Choi, HJ; Lim, JS; Earm, JH; Bee, BH; Kim, IS; Frøkiær, Jørgen; Nielsen, Søren; Kwon, TH.

    In: American Journal of Physiology: Renal Physiology, Vol. 295, No. 1, 2008, p. 300-309.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

     AP214, an analouge of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced actute kidney injury and mortality. / Doi, K; Hu, X; Yuen, PS; Leelahavanichkul, A; Yasuda, H; Kim, SM; Schnermann, J; Jonassen, TE; Frøkiær, Jørgen; Nielsen, Søren.

    In: Kidney International, Vol. 73, No. 11, 2008, p. 1266-1274.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

     Increased renal adrenomedullin expression in rats with ureteral obstruction. / Nørregaard, Rikke; Bødker, Tina; Jensen, BL; Stødkilde-Jørgensen, Lene; Nielsen, Søren; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2007
  19. Published

    Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice. / Rojek, Aleksandra M.; Skowronski, Mariusz T.; Füchtbauer, Ernst Martin; Füchtbauer, Annette C.; Fenton, Robert A.; Agre, Peter; Frøkiær, Jørgen; Nielsen, Søren.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 9, 27.02.2007, p. 3609-3614.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Characterization of a rat model of right-sided heart failure induced by pulmonary trunk banding. / Schou, Uffe K.; Peters, Christian Daugaard; Wan Kim, Soo; Frøkiær, Jørgen; Nielsen, Søren.

    In: Journal of Experimental Animal Science, Vol. 43, No. 4, 26.02.2007, p. 237-254.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism. / Skowronski, Mariusz; Lebeck, Janne; Rojek, Aleksandra; Prætorius, Jeppe; Füchtbauer, Ernst-Martin; Frøkiær, Jørgen; Nielsen, Søren.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, No. 3, 2007, p. F956-65.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    AT1 receptor blockade prevents interstitial and glomerular apoptosis but not fibrosis in pigs with neonatal induced partial unilateral ureteral obstruction. / Eskild-Jensen, Anni; Paulsen, LF; Wogensen, Lise; Olesen, P; Pedersen, Lene; Frøkiær, Jørgen; Nyengaard, Jens Randel.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, No. 6, 2007, p. 1771-1781.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Acute growth hormone administration induces antidiuretic and antinatriuretic effects and increases phosphorylation of NKCC2. / Dimke, Henrik Anthony; Flyvbjerg, Allan; Bourgeois, Soline; Thomsen, Klaus; Frøkiær, Jørgen; Houillier, P; Nielsen, Søren; Frische, Sebastian.

    In: American Journal of Physiology: Renal Physiology, Vol. 92, No. 2, 2007, p. 723-735.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction. / Li, Chunling; Wang, W; Nørregaard, Rikke; Knepper, Mark A; Nielsen, Søren; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, Vol. 293, No. 1, 2007, p. 333-341.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence. / Liu, Y; Promeneur, D; Rojek, Aleksandra; Kumar, N; Frøkiær, Jørgen; Nielsen, Søren; King, LS; Agre, Peter; Carbrey, JM.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 30, 2007, p. 12560-12564.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Aquaporin Water Channels in Mammalian Kidney. / Nielsen, Søren; Kwon, Th.; Dimke, Henrik Anthony; Frøkiær, Jørgen.

    4th edition ed. In the Kidney, 2007.

    Research output: Book/anthology/dissertation/reportBookResearch

  27. Published

    Basis and therapeutical rationale of the urinary concentrating mechanism. / Rittig, S; Frøkiaer, J.

    In: International Journal of Clinical Practice. Symposium Supplement, No. 155, 2007, p. 2-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Biodistribution and tracer kinetics in small and large animals of 99mTc-HYNIC-lactadherin compared to 99mTc-HYNIC-annexin V. / Falborg, Lise; Wæhrens, Lasse Neumann; Alsner, Jan; Dissing, Thomas Heide; Eilersen, J; Frøkiær, Jørgen; Heegaard, Christian Wurtz; Horsman, Michael Robert; Rasmussen, Jan Trige; Nielsen, Søren Steen; Rehling, Michael.

    In: European Journal of Nuclear Medicine and Molecular Imaging, 2007, p. S395.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  29. Published

    COX-2 activity transiently contributes to increased water and NaCl excretion in the polyuric phase after release of ureteral obstruction. / Nørregaard, Rikke; Jensen, BL; Topcu, Sükrü; Aamann, Maria Aaen Diget; Schweer, H; Knepper, Mark A; Nielsen, Søren; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, No. 5, 2007, p. 1322-1333.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Candesartan prevents long-term impairment of renal function in response to neonatal partial unilateral ureteral obstruction. / Topcu, Sükrü; Pedersen, Michael; Nørregaard, Rikke; Wang, Guixian; Knepper, Mark; Djurhuus, Jens Christian; Nielsen, Søren; Jørgensen, Troels Munk; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, 2007, p. F736-748.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  31. Submitted

    Downregulation of key renal acid-base transport proteins in associated with urinary acidification defect in response to uniary tract obstruction. / Wang, Guixian; Li, Chunling; Kim, SW; Wen, JG; Djurhuus, Jens Christian; Wang, W; Nielsen, Søren; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Dynamic Gd-DTPA enhanced MRI renal vasopression deficiency. / Pedersen, Michael; Wen, JG; Frøkiær, Jørgen; Djurhuus, Jens Christian.

    In: Vet Radiol Med Ultrasound, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Effects of a-Lipoic Acid on Ischemia/Reperfusion-Induced Renal Dysfunction in Rats. / Bae, EH; Lee, KS; Lee, J; Ma, SK; Choi, KC; Frøkiær, Jørgen; Nielsen, Søren; Kim, SY; Kim, SH; Kim, SW.

    In: American Journal of Physiology: Renal Physiology, Vol. 294, No. 1, 2007, p. F272-F280.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Effects of alpha-lipoic acid on ischemia-reperfusion-induced renal dysfunction in rats. / Bae, Eun Hui; Lee, Kyun Sang; Lee, Jongun; Ma, Seong Kwon; Kim, Nam Ho; Choi, Ki Chul; Frøkiaer, Jørgen; Nielsen, Søren; Kim, Sun Young; Kim, Sung Zoo; Kim, Suhn Hee; Kim, Soo Wan.

    In: American Journal of Physiology: Renal Physiology, Vol. 294, No. 1, 2007, p. F272-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Furosemide increases water content in renal tissue. / Pedersen, Michael; Vajda, Zsolt; Stødkilde-Jørgensen, Hans; Nielsen, Søren; Frøkiær, Jørgen.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, No. 5, 2007, p. F1645-F1651.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Gender Differences in Nighttime Plasma Arginine Vasopressin and Delayed Compensatory Urine Output in the Elderly Population After Desmopressin. / Hvistendahl, Gitte M.; Frøkiær, Jørgen; Nielsen, Søren; Djurhuus, Jens Christian.

    In: J. Urol., Vol. 178, No. 6, 2007, p. 2671-2676.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Hemodynamic and molecular changes in the solitary kidney in response to neonatal partial ureteral obstruction. / Topcu, Sükrü; Nørregaard, Rikke; Pedersen, Michael; Wang, Guixian; Jørgensen, Troels Munch; Frøkiær, Jørgen.

    Ikke angivet. ed. / Jan Adolfsson. Vol. 41 Scandinavian Journal of Urology and Nephrology, 2007. p. 17.

    Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  38. Published

    Increased AQP2 targeting in primary cultured IMCD cells in response to angiotensin II through AT1 receptor. / Lee, Yu-Jung; Song, In-Kyung; Jang, Kyung-Jin; Nielsen, Jakob; Frøkiær, Jørgen; Nielsen, Søren; Kwon, Tae-Hwan.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, No. 1, 2007, p. F340-50.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Interobserver and within-subject variances of T(2)-relaxation time and (1)H-metabolite ratios in the normal hippocampus. / Højrup, Steen; Jensen, Finn Taagehøj; Simonsen, Carsten; Christensen, T.; Frøkiær, Jørgen; Pedersen, Michael.

    In: J Neuroradiol, Vol. 34, No. 3, 2007, p. 192-204.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney. / Seigneux, Sophie de; Nielsen, Jakob; Olesen, Emma T.B.; Dimke, Henrik Anthony; Kwon, Tae-Hwan; Frøkiær, Jørgen; Nielsen, Søren.

    In: American Journal of Physiology: Renal Physiology, Vol. 293, No. 1, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney. / de Seigneux, Sophie; Nielsen, Jakob; Olesen, Emma T B; Dimke, Henrik; Kwon, Tae-Hwan; Frøkiaer, Jørgen; Nielsen, Søren; Dimke, Henrik Anthony.

    In: American Journal of Physiology: Renal Physiology, Vol. 293, No. 1, 2007, p. F87-99.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade. / Nielsen, Jakob; Kwon, Tae-Hwan; Frøkiær, Jørgen; Knepper, Mark A; Nielsen, Søren.

    In: American Journal of Physiology: Renal Physiology, Vol. 1, No. 292, 2007, p. F382-394.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Ovariectomy in rats is associated with increased renal aquaporin-2, -3, -1 and Na, K-ATPase expression and decreased urine output. / Sardeli, Chris; Kwon, Thomas H; Li, Chunling; Wang, Guixian; Knepper, Mark A; Nielsen, Søren; Frøkiær, Jørgen.

    In: Nephrology, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Pathogenesis of oedema in nephrotic syndrome: Role of epithelial sodium channel. / Kim, SW; Frøkiær, Jørgen; Nielsen, Søren.

    In: Nephrology, No. 12, 2007, p. 8-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Regional changes in renal cortical glucose, lactate and urea during acute unilateral ureteral obstruction. / Krarup, Peter Martin; Stolle, LB; Rawashdeh, Yazan F. H.; Skott, O; Djurhuus, Jens Christian; Frøkiær, Jørgen.

    In: Scandinavian Journal of Urology and Nephrology, Vol. 41, No. 1, 2007, p. 47-53.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Regulation of AQP4 protein expression in rat brain astrocytes: Roles of P2X7 receptor activation. / Lee, MH; Lee, SJ; Choi, H-J; Frøkiær, Jørgen; Nielsen, Søren; Kwon, TH.

    In: Brain Research, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Regulation of Water Balance: Urine Concentration and Dilution. / Nielsen, Søren; Knepper, Mark A.; Kwon, Tae-Hwan; Frøkiær, Jørgen.

    Diseases of the Kidney & Urinary Tract. ed. / Robert W. Schrier. Vol. 1 8. ed. Philadelphia, USA : Lippincott Williams & Wilkins, 2007. p. 96.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  48. Published

    Regulation of water balance: Urine Concentration and dilution. / Nielsen, Søren; Knepper, Mark A; Kwon, Th; Frøkiær, Jørgen.

    Diseases of the kidney and urinary tract, 8th. Edition. 8. ed. Ed. Robert W. Schrier, Lippencott and Wilkins, 2007. p. 96-123.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  49. Published

    Renal compensation to chronic hypoxic hypercapnia: downregulation of pendrin and adaptation of the proximal tubule. / Seigneux, Sophie de; Malte, H.; Dimke, Henrik Anthony; Frøkiær, Jørgen; Nielsen, Søren; Frische, Sebastian.

    In: AJP-Renal, Vol. 292, No. 4, 2007, p. F1256-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Renal compensation to chronic hypoxic hypercapnia: downregulation of pendrin and adaptation of the proximal tubule. / de Seigneux, Sophie; Malte, Hans; Dimke, Henrik; Frøkiaer, Jørgen; Nielsen, Søren; Frische, Sebastian; Dimke, Henrik Anthony.

    In: American Journal of Physiology: Renal Physiology, Vol. 292, No. 4, 2007, p. F1256-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. Published

    Telmisartan attenuates chronic ciclosporin A nephrotoxicity in a pig model. / Cibulskyte, Donata; Pedersen, Michael; Hørlyck, Arne; Marcussen, Niels; Hansen, Hans Erik; Frøkiær, Jørgen; Madsen, Melvin; Mortensen, Jens.

    In: Nephrology, Dialysis, Transplantation, Vol. 22, No. 2, 2007, p. 369-375.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    Vacuolar H+-ATPase expression is increased in acid-secreting intercalated cells in kidneys of rats with hypercalcaemia-induced alkalosis. / Wang, Weidong; Prætorius, Jeppe; Li, Chunling; Prætorius, Helle; Kwon, Tae-Hwan; Frøkiær, Jørgen; Nielsen, Søren.

    In: Acta Physiol (Oxf.), Vol. 189, No. 4, 2007, p. 359-68.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review