Jesper Møller Jensen

Coronary Computed Tomography Angiography Derived Fractional Flow Reserve and Plaque Stress

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Bjarne Linde Nørgaard
  • ,
  • Jonathon Leipsic
  • ,
  • Bon-Kwon Koo
  • ,
  • Christopher K Zarins
  • ,
  • Jesper Møller Jensen
  • Niels Peter Sand
  • ,
  • Charles A Taylor

Fractional flow reserve (FFR) measured during invasive coronary angiography is an independent prognosticator in patients with coronary artery disease and the gold standard for decision making in coronary revascularization. The integration of computational fluid dynamics and quantitative anatomic and physiologic modeling now enables simulation of patient-specific hemodynamic parameters including blood velocity, pressure, pressure gradients, and FFR from standard acquired coronary computed tomography (CT) datasets. In this review article, we describe the potential impact on clinical practice and the science behind noninvasive coronary computed tomography (CT) angiography derived fractional flow reserve (FFRCT) as well as future applications of this technology in treatment planning and quantifying forces on atherosclerotic plaques.

Original languageEnglish
JournalCurrent cardiovascular imaging reports
Pages (from-to)2
Publication statusPublished - 5 Mar 2016

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