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Jesper Lykkegaard Karlsen

Special Consultant

Profile photoJesper Lykkegaard Karlsen
Member of Administrative Staff
Department of Molecular Biology and Genetics - Structural Biology
Gustav Wieds Vej 10, 3135, 209
8000, Aarhus C
Denmark
E-mail: jlk@mb.au.dk
Phone: 87155467
Mobile: 50906203

Publications

Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase

Amstrup, S. K., Ong, S. C., Sofos, N., Karlsen, J. L., Skjerning, R. B., Boesen, T., Enghild, J. J., Hove-Jensen, B. & Brodersen, D. E., Feb 2023, In: Nature Communications. 14, 1001.

Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity

Neumann, C., Rosenbaek, L. L., Flygaard, R. K., Habeck, M., Karlsen, J. L., Wang, Y., Lindorff-Larsen, K., Gad, H. H., Hartmann, R., Lyons, J. A., Fenton, R. A. & Nissen, P., Dec 2022, In: The EMBO Journal. 41, 23, 15 p., e110169.

Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase

Amstrup, S. K., Sofos, N. E., Karlsen, J. L., Skjerning, R. B., Boesen, T., Enghild, J. J., Hove-Jensen, B. & Brodersen, D. E., Jun 2022, bioRxiv, 34 p.

Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family

Nielsen, N. S., Zarantonello, A., Harwood, S. L., Jensen, K. T., Kjøge, K., Thøgersen, I. B., Schauser, L., Karlsen, J. L., Andersen, G. R. & Enghild, J. J., May 2022, In: Nature Communications. 13, 1, 15 p., 3033.

Structural Remodelling of the Carbon-Phosphorus Enzymatic Machinery by a Dual ATP-Binding Cassette Module

Brodersen, D. E., Amstrup, S. K., Sofos, N. E., Karlsen, J., Skjerning, R., Boesen, T., Enghild, J. J. & Jensen, B. H., May 2022, In: The FASEB Journal. 36 , S1

Structure and autoregulation of a P4-ATPase lipid flippase

Timcenko, M., Lyons, J. A., Januliene, D., Ulstrup, J. J., Dieudonné, T., Montigny, C., Ash, M. R., Karlsen, J. L., Boesen, T., Kühlbrandt, W., Lenoir, G., Moeller, A. & Nissen, P., Jul 2019, In: Nature. 571, 7765, p. 366-370 5 p.

Namdinator - Automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

Kidmose, R. T., Juhl, J., Nissen, P., Boesen, T., Karlsen, J. L. & Pedersen, B. P., 2019, In: IUCrJ. 6, 4, p. 526-531 6 p.

Initiating heavy-atom-based phasing by multi-dimensional molecular replacement

Pedersen, B. P., Gourdon, P., Liu, X., Karlsen, J. L. & Nissen, P., 1 Mar 2016, In: Acta crystallographica Section D: Structural biology . 72, Pt 3, p. 440-445 6 p.

How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations: The P-Type ATPase Example

Karlsen, J. L. & Bublitz, M., 2016, Methods in Molecular Biology: Methods and Protocols. Bublitz, M. (ed.). New York: Springer, Vol. 1377. p. 523-39 17 p. (Methods in molecular biology (Clifton, N.J.)).

Initiating Heavy-atom Based Phasing by Multi-Dimensional Molecular Replacement

Pedersen, B. P., Gourdon, P., Liu, X., Lykkegaard Karlsen, J. & Nissen, P., 28 Mar 2014, In: arXiv. 1403.7484

The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm

Winther, A-M. L., Bublitz, M., Karlsen, J. L., Møller, J. V., Hansen, J. B., Nissen, P. & Buch-Pedersen, M. J., 14 Mar 2013, In: Nature. 495, 7440, p. 265-269 5 p.

The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor

Hamming, O. J., Kang, L., Svensson, A., Karlsen, J. L., Rahbek-Nielsen, H., Paludan, S. R., Hjorth, S. A., Bondensgaard, K. & Hartmann, R., 16 Mar 2012, In: Journal of Biological Chemistry. 287, p. 9454-9460 7 p.

Structural models of the human copper P-type ATPases ATP7A and ATP7B

Gourdon, P., Sitsel, O., Karlsen, J. L., Møller, L. B. & Nissen, P., 1 Mar 2012, In: Biological Chemistry. 393, 4, p. 205-216 12 p.