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Jens Stougaard

Professor

Curriculum Vitae

Professor Jens Stougaard, Director of Centre for Carbohydrate Recognition and Signalling.

Department of Molecular Biology, Aarhus University, Gustav Wieds Vej 10, Aaarhus 8000 C, Denmark. 

Phone: +45 87155504 or 60202649, e-mail: stougaard@mb.au.dk

 

Employment:

2006 –             Professor, Department of Molecular Biology, University of Aarhus

1994 – 2006    Associate Professor, Department of Molecular and Structural Biology,

1990 – 1994    Assistant Professor, Department of Molecular Biology, University of Aarhus.

1986 – 1989    Department of Molecular Biology, University of Aarhus. Post-doctoral fellowship from the Danish FTU program.

1983 – 1986    Department of Molecular Biology, University of Aarhus. Post-doctoral fellowship from the Danish Agricultural Research Council.

1979 – 1983    AFRC-Unit of Nitrogen Fixation, University of Sussex, Brighton, U.K.


Education and Training:

1990               Visiting scientist at The Sainsbury Laboratory, Norwich, UK.

1984               Max-Planck Institut für Züchtungsforschung, Cologne, Germany,OECD Fellowship

1983-1989      Post-doctoral Research, Department of Molecular Biology, University of Aarhus

1979-1983      PhD, AFRC-Unit of Nitrogen Fixation, University of Sussex, Brighton, U.K.,

1975-1979      MSc, The Royal Veterinary and Agricultural University. University of Copenhagen.

                       

Scientific summary:

Plant-microbe interactions. Receptors involved in endosymbiosis. Signal transduction processes in plants. Plant genes and small RNAs regulating root nodule development.  Legume seed development. Carbohydrate signal in symbiosis and plant development. 

 

Professional distinctions:

2016                Knighted by the Queen of Denmark

2016                The Villum Kann Rasmussen Annual Award for Technical and Scientific Research

2016                Elected member of Academia Europaea

2014                Highly Cited Researchers 2014, ranked among the top 1% most cited

2014                Elected member of The Danish Academy of Technical Sciences (ATV)

2012                Leader of Advanced Grant project awarded by the European Research Council 

2007                Director of the Centre for Carbohydrate Recognition and Signalling, a Centre of Excellence funded by the Danish National Research Foundation

2005                Elected member of European Molecular Biology Organization (EMBO)

 

 

Current funding and projects:

Centre for Carbohydrate Recognition and Signalling (CARB), Centre of Excellence the Danish National Reseach Foundation. 2012-2017

Carbohydrate Signals Controlling Nodulation (CASINO), ERC Advanced Grant. 2012 -2017

Engineering Nitrogen Symbiosis for Africa (ENSA), Bill & Melinda Gates Foundation. 2013-2018. This project has 8 international partners.

Decoding ligand-receptor specificities of LYSM-proteins by plant immity and symbiosis (SIPIS), ERA-CAPS. 2015 – 2018

NORFAB: Protein for the Northern Hemisphere (NORFAB), Innovationsfonden. 2016 – 2021

 

 

Supervision:

1988-2016       Ph.D supervisor for 35 students

1984-2016       Supervisor for more than twenty final year projects in Plant Molecular Biology/Molecular Genetics

 

Professional Society Memberships:

Elected to the International Society of Molecular Plant Microbe Interactions (MPMI) board of directors, 2016

Elected member of EMBO the European Molecular Biology Organization

Experimental Biology Society

The American Phytopathological Society.

International Society for Molecular Plant-Microbe Interactions.

Scandinaviam Plant Physiology Society

 

Organization of meetings:

President of the Board for the European Nitrogen Fixation Conferences.

Member of the International Scientific Advisory Board on the EuroConferences; Molecular Genetics of Model Legumes.

Member of the International Scientific Advisory Board for the International Conference on Legume Genetics and Genomics.

Member of the International Scientific Advisory Board for the International Congress on Molecular Plant-Microbe Interactions

Member of The International Advisory Board for the International Congress on Nitrogen Fixation

Forskningsdag om Planteforædling og Bioteknologi, 1996 and 1997, University of Odense.

1st International Workshop on Lotus japonicus. University of Aarhus, Denmark, 1998.

7th European Nitrogen Fixation Conference, 2006 Aarhus Denmark

 

Services to the scientific community:

Elected to the International Society of Molecular Plant-Microbe Interaction (IS-MPMI) board of Directors in 2016

Serving member of the EMBO committee for Courses and Workshops

External peer reviewer  for NSF, National Science Foundation and USDA, Washington DC; The Royal Society, London; BBSRC, Biotechnology and Biological Sciences Research Council, London; DFG, Germany; Marsden Foundation, New  Zealand; Research Foundation Flanders-FWO; ERC-European Research Council.

 

Referee for several international journals including Nature, Science, PNAS, EMBO Journal, Genes and Development, Plant Cell, Plant Journal, Plant Physiology, Plant Molecular Biology, Molecular Plant-Microbe Interactions, and others.

 

2001-2003 Senior Editor for (MPMI)  Molecular Plant-Microbe Interactions

2003- 2006 Editor-in-Chief, (MPMI) Molecular Plant-Microbe Interactions

2004–2007 Member of the American Phytopathology Associations publication board

 

2004- 2008 Co-ordinator for Større Tværgående Forskergrupper project

Member of manager group for EU-INTEGRAL project with 10 partners

 

University committees:

Member of advisory committee for the Science Faculty Dean

Head of Research Committee for Department of Molecular Biology

University representative in Plant Biotech Denmark Consortium steering committee

Member of the PhD committee at the Science Faculty

 

Ministerial appointments:

2011 – 2014 Member of Innovationsfondens program committee for Health, Food and Welfare.

2005 Member of Ministry of Food, Agriculture and Fisheries Steering Committee for Strategy paper on Non-Food

2004 Member of Ministry of Food, Agriculture and Fisheries Steering Committee for Strategy paper on Biotechnology.

2005 – 07 Member of the Danish Research Council for Production and Technology 

2003 – 07 Danish Representative in ERA-NAT Plant Genomics Network Steering Committee

2001 – 04 Member of the Ministry of Food,Agriculture and Fisheries, Scientific Advisory Committee

2000 – 05 Member of the Danish Agricultural and Veterinary Research Council

 

Current projects:

2015 – 2021. NORFAB: Proteins for the Northern Hemisphere. Innovation Fund Denmark

2015 – 2018. SIPIS ERA-CAPS. Innovation Fund Denmark

2016 – 2021. Engineering Nitrogen Symbiosis for Africa (ENSA), 2016-2021. Bill & Melinda Gates Foundation.

 

Publications: 

137 publications, including 10 in Nature and Science.

15 reviews in peer reviewed journals

4 submitted manuscripts under review or revision

12 laboratory manuals in cell biology and genetics

1 Monograph, 8 book chapters

3 licensed patents or patent applications

Numerous Abstracts and Proceedings from International Meetings

Highly Cited Researchers, ranked among the top 1% most cited in animal and plant science

h-index WoS 57, Google Scholar 62

 

Central publications:

Handberg, K., and Stougaard, J. (1992) Lotus japonicus, an autogamous diploid legume species for classical and molecular genetics.       Plant  J. 2, 487-496.

 

Schauser, L., Roussis, A., Stiller, J., and Stougaard, J. (1999) A plant regulator controlling development of symbiotic root nodules. Nature, 402, 191-195.

 

Krusell,  L., Madsen L.H,, Genua, A., Szczyglowski, K., Aubert, G., Duc, G., Sato, S., Tabata, S., de Bruijn, F., Pajuelo, E., Sandal, N., Stougaard, J. (2002) Shoot control of root development and nodulation is mediated by a receptor-like kinase. Nature, 420, 422-426.

 

Radutoiu, S., Madsen, L.H, Madsen, E.B, Felle, H., Umehara, Y., Grønlund, M., Kaneko, T., Sato, S., Tabata, S., Sandal N. and Stougaard, J. (2003) Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases. Nature 425, 585-592.

 

Madsen, E.B., Madsen, L.H., Radutoiu, S., Olbryt, M., Rakwalska, M., Szczyglowski, K., Kaneko, T., Sato, S., Tabata, S., Sandal, N. and Stougaard, J.  (2003) A receptor-like kinase gene involved in legume perception of rhizobial signal molecules. Nature, 425, 637-640.

 

Kanamori, N., Madsen, L.H., Radutoiu, S., Frantescu, M., Quistgaard, E.M.H., Miwa, H., Downie, J.A., James, E., Felle, H.H., Haaning, L.L., Jensen, T.H., Sato, S., Nakamura, Y., Tabata, S., Sandal, N., and Stougaard, J. (2006) A nucleoporin is required for induction of Ca2+ spiking in legume nodulation and is essential for rhizobial and fungal endosymbioses. PNAS, 103, 359-364.

 

Tirichine, L., Imaizumi-Anraku, H., Yoshida, S., Murakami, Y., Madsen, L.H., Miwa, H., Nakagawa, T., Sandal, N., Albrektsen, A., Kawaguchi, M., Downie, A., Sato, S., Tabata, S., Kouchi, H., Parniske, M., Kawasaki, S. and Stougaard, J. (2006) Deregulation of a Ca2+/calmodulin-dependent kinase leads to spontaneous nodule development.Nature441, 1153-1156.

 

Tirichine, L., Sandal, N., Madsen, L.H., Radutoiu, S., Albrektsen, A., Sato, S., Asamizu, E., TabataS. and Stougaard, J. (2007) A gain of function mutation in a cytokinin receptor triggers spontaneous root nodule organogenesis.  Science 315, 104-107

 

Radutoiu, S., Madsen, L.H., Madsen, E.B., Jurkiewicz, A., Fukai, E., Quistgaard E.M.H., Albrektsen, A.S., James, E.K,. Thirup, S., and Stougaard, J. (2007) LysM domains mediate lipochitin-oligosaccharide recognition and Nfr genes extend the symbiotic host range. EMBO J 26, 3923- 3935.

 

Madsen, L.H., Tirichine, L., Jurkiewicz, A., Sullivan, J.T., Heckmann, A.B., Bek, A.S., Ronson, C.W., James, E.K.,  and Stougaard J. (2010) The molecular network governing nodule organogenesis and infection in the model legume Lotus japonicus. Nature Communications, DOI:10.1038/ncomms1009.

 

Broghammer, A., Krusell, L., Blaise, M., Sauer, J., Sullivan, J.T.,  Maolanon, N., Vinther, M., Lorentzen, A., Madsen, E.B.,  Jensen, K.J., Roepstorff, P., Thirup, S., Ronson, C.W., ThygesenM.B. and Stougaard, J.(2012) . Legume receptors perceive the rhizobial lipochito-oligosaccharide signal molecules by direct binding. PNAS 109, 13859-13864.

 

Wong, J., Alsarraf, H., Kaspersen, J., Pedersen, J., Stougaard, J., Thirup, S., and Blaise, M. (2014) Cooperative binding of LysM domains determines the carbohydrate affinity of a bacterial endopeptidase protein. FEBS J. 281, 1196-1208.

 

Holt, D.B., Gupta, V., Meyer, D., Abel, N., Andersen, S.U., Stougaard, J. and Markmann, K. (2015) miR172 signals epidermal infection and is expressed in cells primed for bacterial invasion in Lotus japonicus roots and nodules. New Phytol 208, 241-256.

 

Kawaharada Y., Kelly S., Wibroe Nielsen M., Hjuler C.T, Gysel K., Muszyński A., Carlson, RW., Thygesen, M.B., Sandal N., Asmussen M.H., Vinther M., Andersen S.U., Krusell L., Thirup, S., Jensen, K.J., Ronson, C.W., Blaise, M., Radutoiu, S. & Stougaard, J. (2015) Receptor-mediated exopolysaccharide perception controls bacterial infection. Nature523, 308-312.

 

Reid,D.E., Heckmann,A.B., Novák,O., Kelly,S., and Stougaard,J. (2016) CYTOKININ OXIDASE/DEHYDROGENASE3 maintains cytokinin homeostasis assuring optimal root and nodule development in Lotus japonicus. Plant Phys170, 1060-1074.

 

Malolepszy, A., Mun, T., Sandal, N., Gupta, V., Dubin, M., Urbański, D., Shah, N., Bachmann, A., Fukai, E., Hirakawa, H., Tabata, S., Nadzieja, M., Markmann, K., Su, J., Umehara, Y., Soyano, T., Miyahara, A., Sato, S., Hayashi, M., Stougaard, J., Andersen, S.U.(2016) The LORE1 insertion mutant resource. Plant Journal. DOI: 10.1111/tpj.13243