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Jens Randel Nyengaard

Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain

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Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain. / Khan, Ahmad Raza; Chuhutin, Andrey; Wiborg, Ove; Kroenke, Christopher D; Nyengaard, Jens R.; Hansen, Brian; Jespersen, Sune Nørhøj.

In: Data in Brief, Vol. 8, 2016, p. 934-937.

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@article{a8ed7ed516a54ad9a7baf3e9e8e11fe3,
title = "Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain",
abstract = "Abstract This data article describes a large, high resolution diffusion MRI data set from fixed rat brain acquired at high field strength. The rat brain samples consist of21adult rat brain hemispheres from animals exposed to chronic mild stress (anhedonic and resilient) and controls. Histology from amygdala of the same brain hemispheres is also included with three different stains: DiI and Hoechst stained microscopic images (confocal microscopy) andALDH1L1 antibody based immunohistochemistry.These stains may be used to evaluate neurite density (DiI), nuclear density (Hoechst) and astrocytic density (ALDH1L1). This combination of high field diffusion data and high resolution images from microscopy enables comparison of microstructural parameters derived from diffusion MRIto histological microstructure. The data provided here is used in the article (Jespersen, 2016) [1].",
keywords = "Chronic mild stress, Diffusion MRI, Neurite, Histology",
author = "Khan, {Ahmad Raza} and Andrey Chuhutin and Ove Wiborg and Kroenke, {Christopher D} and Nyengaard, {Jens R.} and Brian Hansen and Jespersen, {Sune N{\o}rh{\o}j}",
year = "2016",
doi = "10.1016/j.dib.2016.06.061",
language = "English",
volume = "8",
pages = "934--937",
journal = "Data Brief",
issn = "2352-3409",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain

AU - Khan, Ahmad Raza

AU - Chuhutin, Andrey

AU - Wiborg, Ove

AU - Kroenke, Christopher D

AU - Nyengaard, Jens R.

AU - Hansen, Brian

AU - Jespersen, Sune Nørhøj

PY - 2016

Y1 - 2016

N2 - Abstract This data article describes a large, high resolution diffusion MRI data set from fixed rat brain acquired at high field strength. The rat brain samples consist of21adult rat brain hemispheres from animals exposed to chronic mild stress (anhedonic and resilient) and controls. Histology from amygdala of the same brain hemispheres is also included with three different stains: DiI and Hoechst stained microscopic images (confocal microscopy) andALDH1L1 antibody based immunohistochemistry.These stains may be used to evaluate neurite density (DiI), nuclear density (Hoechst) and astrocytic density (ALDH1L1). This combination of high field diffusion data and high resolution images from microscopy enables comparison of microstructural parameters derived from diffusion MRIto histological microstructure. The data provided here is used in the article (Jespersen, 2016) [1].

AB - Abstract This data article describes a large, high resolution diffusion MRI data set from fixed rat brain acquired at high field strength. The rat brain samples consist of21adult rat brain hemispheres from animals exposed to chronic mild stress (anhedonic and resilient) and controls. Histology from amygdala of the same brain hemispheres is also included with three different stains: DiI and Hoechst stained microscopic images (confocal microscopy) andALDH1L1 antibody based immunohistochemistry.These stains may be used to evaluate neurite density (DiI), nuclear density (Hoechst) and astrocytic density (ALDH1L1). This combination of high field diffusion data and high resolution images from microscopy enables comparison of microstructural parameters derived from diffusion MRIto histological microstructure. The data provided here is used in the article (Jespersen, 2016) [1].

KW - Chronic mild stress

KW - Diffusion MRI

KW - Neurite

KW - Histology

U2 - 10.1016/j.dib.2016.06.061

DO - 10.1016/j.dib.2016.06.061

M3 - Journal article

C2 - 27508246

VL - 8

SP - 934

EP - 937

JO - Data Brief

JF - Data Brief

SN - 2352-3409

ER -