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Jens Randel Nyengaard

Sex differences in regional specialisation across the placental surface

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Sex differences in regional specialisation across the placental surface. / Alwasel, S H; Harrath, A H; Aldahmash, W M; Abotalib, Z; Nyengaard, J R; Osmond, C; Dilworth, M R; Al Omar, S Y; Jerah, A A; Barker, D J P.

In: Placenta, Vol. 35, No. 6, 06.2014, p. 365-9.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Alwasel, SH, Harrath, AH, Aldahmash, WM, Abotalib, Z, Nyengaard, JR, Osmond, C, Dilworth, MR, Al Omar, SY, Jerah, AA & Barker, DJP 2014, 'Sex differences in regional specialisation across the placental surface', Placenta, vol. 35, no. 6, pp. 365-9. https://doi.org/10.1016/j.placenta.2014.03.003

APA

Alwasel, S. H., Harrath, A. H., Aldahmash, W. M., Abotalib, Z., Nyengaard, J. R., Osmond, C., Dilworth, M. R., Al Omar, S. Y., Jerah, A. A., & Barker, D. J. P. (2014). Sex differences in regional specialisation across the placental surface. Placenta, 35(6), 365-9. https://doi.org/10.1016/j.placenta.2014.03.003

CBE

Alwasel SH, Harrath AH, Aldahmash WM, Abotalib Z, Nyengaard JR, Osmond C, Dilworth MR, Al Omar SY, Jerah AA, Barker DJP. 2014. Sex differences in regional specialisation across the placental surface. Placenta. 35(6):365-9. https://doi.org/10.1016/j.placenta.2014.03.003

MLA

Vancouver

Alwasel SH, Harrath AH, Aldahmash WM, Abotalib Z, Nyengaard JR, Osmond C et al. Sex differences in regional specialisation across the placental surface. Placenta. 2014 Jun;35(6):365-9. https://doi.org/10.1016/j.placenta.2014.03.003

Author

Alwasel, S H ; Harrath, A H ; Aldahmash, W M ; Abotalib, Z ; Nyengaard, J R ; Osmond, C ; Dilworth, M R ; Al Omar, S Y ; Jerah, A A ; Barker, D J P. / Sex differences in regional specialisation across the placental surface. In: Placenta. 2014 ; Vol. 35, No. 6. pp. 365-9.

Bibtex

@article{8af97e42082a4f4a97aaae2454d15021,
title = "Sex differences in regional specialisation across the placental surface",
abstract = "There may be regional specialisation in structure and function across the placental surface. In Riyadh, Saudi Arabia, the length and the breadth of the placental surface at birth were highly correlated, but the breadth was more closely associated with the size of the baby. To replicate this we studied 321 pregnant Saudi women in the town of Baish. We measured the size of the newborn babies and their placentas. The association of the length and breadth of the placental surface on the baby's body size differed in boys and girls. Among boys the breadth had a stronger association with all birth measurements except crown-heel length. This was similar to the findings in Riyadh. Placental surface length was related to crown-heel length. For each centimetre in surface length, crown-heel length increased by 0.27 cm (95% CI 0.09-0.44, p = 0.004). Among girls placental surface breadth was related to crown-heel length, whereas surface length was related to birth weight, head and thigh circumferences. For each centimetre in surface breadth, crown-heel length increased by 0.33 cm (0.13-0.53, p = 0.001). We conclude that, within Saudi Arabia, there are both geographical and sex differences in regional specialisation across the placental surface. In the adverse circumstances of Baish, linked to the mothers' short stature, boys were smaller at birth than girls. Boys may have compensated for under-nutrition by increasing the depth of spiral artery invasion rather than by recruiting additional spiral arteries. Girls may have had more effective regional specialisation across the placental surface.",
keywords = "Anthropometry, Birth Weight, Body Height, Body Size, Female, Fetal Development, Gestational Age, Humans, Infant, Newborn, Male, Maternal Age, Mothers, Parity, Placenta, Pregnancy, Saudi Arabia, Sex Characteristics",
author = "Alwasel, {S H} and Harrath, {A H} and Aldahmash, {W M} and Z Abotalib and Nyengaard, {J R} and C Osmond and Dilworth, {M R} and {Al Omar}, {S Y} and Jerah, {A A} and Barker, {D J P}",
note = "Copyright {\textcopyright} 2014 Elsevier Ltd. All rights reserved.",
year = "2014",
month = jun,
doi = "10.1016/j.placenta.2014.03.003",
language = "English",
volume = "35",
pages = "365--9",
journal = "Placenta",
issn = "0143-4004",
publisher = "Elsevier Ltd",
number = "6",

}

RIS

TY - JOUR

T1 - Sex differences in regional specialisation across the placental surface

AU - Alwasel, S H

AU - Harrath, A H

AU - Aldahmash, W M

AU - Abotalib, Z

AU - Nyengaard, J R

AU - Osmond, C

AU - Dilworth, M R

AU - Al Omar, S Y

AU - Jerah, A A

AU - Barker, D J P

N1 - Copyright © 2014 Elsevier Ltd. All rights reserved.

PY - 2014/6

Y1 - 2014/6

N2 - There may be regional specialisation in structure and function across the placental surface. In Riyadh, Saudi Arabia, the length and the breadth of the placental surface at birth were highly correlated, but the breadth was more closely associated with the size of the baby. To replicate this we studied 321 pregnant Saudi women in the town of Baish. We measured the size of the newborn babies and their placentas. The association of the length and breadth of the placental surface on the baby's body size differed in boys and girls. Among boys the breadth had a stronger association with all birth measurements except crown-heel length. This was similar to the findings in Riyadh. Placental surface length was related to crown-heel length. For each centimetre in surface length, crown-heel length increased by 0.27 cm (95% CI 0.09-0.44, p = 0.004). Among girls placental surface breadth was related to crown-heel length, whereas surface length was related to birth weight, head and thigh circumferences. For each centimetre in surface breadth, crown-heel length increased by 0.33 cm (0.13-0.53, p = 0.001). We conclude that, within Saudi Arabia, there are both geographical and sex differences in regional specialisation across the placental surface. In the adverse circumstances of Baish, linked to the mothers' short stature, boys were smaller at birth than girls. Boys may have compensated for under-nutrition by increasing the depth of spiral artery invasion rather than by recruiting additional spiral arteries. Girls may have had more effective regional specialisation across the placental surface.

AB - There may be regional specialisation in structure and function across the placental surface. In Riyadh, Saudi Arabia, the length and the breadth of the placental surface at birth were highly correlated, but the breadth was more closely associated with the size of the baby. To replicate this we studied 321 pregnant Saudi women in the town of Baish. We measured the size of the newborn babies and their placentas. The association of the length and breadth of the placental surface on the baby's body size differed in boys and girls. Among boys the breadth had a stronger association with all birth measurements except crown-heel length. This was similar to the findings in Riyadh. Placental surface length was related to crown-heel length. For each centimetre in surface length, crown-heel length increased by 0.27 cm (95% CI 0.09-0.44, p = 0.004). Among girls placental surface breadth was related to crown-heel length, whereas surface length was related to birth weight, head and thigh circumferences. For each centimetre in surface breadth, crown-heel length increased by 0.33 cm (0.13-0.53, p = 0.001). We conclude that, within Saudi Arabia, there are both geographical and sex differences in regional specialisation across the placental surface. In the adverse circumstances of Baish, linked to the mothers' short stature, boys were smaller at birth than girls. Boys may have compensated for under-nutrition by increasing the depth of spiral artery invasion rather than by recruiting additional spiral arteries. Girls may have had more effective regional specialisation across the placental surface.

KW - Anthropometry

KW - Birth Weight

KW - Body Height

KW - Body Size

KW - Female

KW - Fetal Development

KW - Gestational Age

KW - Humans

KW - Infant, Newborn

KW - Male

KW - Maternal Age

KW - Mothers

KW - Parity

KW - Placenta

KW - Pregnancy

KW - Saudi Arabia

KW - Sex Characteristics

U2 - 10.1016/j.placenta.2014.03.003

DO - 10.1016/j.placenta.2014.03.003

M3 - Journal article

C2 - 24709557

VL - 35

SP - 365

EP - 369

JO - Placenta

JF - Placenta

SN - 0143-4004

IS - 6

ER -