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Jens Randel Nyengaard

Naturally occurring variation in the glutathione-s-transferase 4 gene determines neurodegeneration after traumatic brain injury

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Faiez Al Nimer
  • ,
  • Mikael Ström
  • ,
  • Rickard Lindblom
  • ,
  • Shahin Aeinehband
  • ,
  • Bo-Michael Bellander
  • ,
  • Jens R Nyengaard
  • Olle Lidman
  • ,
  • Fredrik Piehl
Genetic factors are important for outcome after traumatic brain injury (TBI), although exact knowledge of relevant genes/pathways is still lacking. We here used an unbiased approach to define differentially activated pathways between the inbred DA and PVG rat strains. The results prompted us to study further if a naturally occurring genetic variation in glutathione-S-transferase alpha 4 (Gsta4) affects the outcome after TBI.
Original languageEnglish
JournalAntioxidants & Redox Signaling
Volume18
Issue7
Pages (from-to)784-94
Number of pages11
ISSN1523-0864
DOIs
Publication statusPublished - 1 Mar 2013

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