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Jens Randel Nyengaard

Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy

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Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy. / Mechlenburg, Inger; Nyengaard, Jens R; Gelineck, John; Søballe, Kjeld; Troelsen, Anders.

In: Clinical Orthopaedics and Related Research, 2010.

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@article{8fce3da0418811df9806000ea68e967b,
title = "Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy",
abstract = "BACKGROUND: Untreated hip dysplasia can result in a degenerative process joint and secondary osteoarthritis at an early age. While most periacetabular osteotomies (PAOs) are performed to relieve symptoms, the osteotomy is presumed to slow or prevent degeneration unless irreparable damage to the cartilage has already occurred. QUESTIONS/PURPOSES: We therefore determined (1) whether changes in the thickness of the cartilage in the hip occur after PAO, and (2) how many patients had an acetabular labral tear and whether labral tears are associated with thinning of the cartilage after PAO. PATIENTS AND METHODS: We prospectively followed 22 women and four men with hip dysplasia with MRI before PAO and again 1 year and 2(1/2) years postoperatively to determine if cartilage thinning (reflecting osteoarthritis) occurred. The thickness of the femoral and acetabular cartilage was estimated with a stereologic method. Three and one-half years postoperatively, 18 of 26 patients underwent MR arthrography to investigate if they had a torn acetabular labrum. RESULTS: The acetabular cartilage thickness differed between 1 and 2(1/2) years postoperatively (preoperative 1.40 mm, 1 year postoperatively 1.47 mm, and 2(1/2) years postoperatively 1.35 mm), but was similar at all times for the femoral cartilage (preoperative 1.38 mm, 1 year postoperatively 1.43 mm, and 2(1/2) years postoperatively 1.38 mm.) Seventeen of 18 patients had a torn labrum. The tears were located mainly superior on the acetabular rim. CONCLUSION: Cartilage thickness 2(1/2) years after surgery compared with preoperatively was unchanged indicating the osteoarthritis had not progressed during short-term followup after PAO.",
author = "Inger Mechlenburg and Nyengaard, {Jens R} and John Gelineck and Kjeld S{\o}balle and Anders Troelsen",
year = "2010",
doi = "10.1007/s11999-010-1310-z",
language = "English",
journal = "Clinical Orthopaedics and Related Research",
issn = "0009-921X",
publisher = "Springer New York LLC",

}

RIS

TY - JOUR

T1 - Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy

AU - Mechlenburg, Inger

AU - Nyengaard, Jens R

AU - Gelineck, John

AU - Søballe, Kjeld

AU - Troelsen, Anders

PY - 2010

Y1 - 2010

N2 - BACKGROUND: Untreated hip dysplasia can result in a degenerative process joint and secondary osteoarthritis at an early age. While most periacetabular osteotomies (PAOs) are performed to relieve symptoms, the osteotomy is presumed to slow or prevent degeneration unless irreparable damage to the cartilage has already occurred. QUESTIONS/PURPOSES: We therefore determined (1) whether changes in the thickness of the cartilage in the hip occur after PAO, and (2) how many patients had an acetabular labral tear and whether labral tears are associated with thinning of the cartilage after PAO. PATIENTS AND METHODS: We prospectively followed 22 women and four men with hip dysplasia with MRI before PAO and again 1 year and 2(1/2) years postoperatively to determine if cartilage thinning (reflecting osteoarthritis) occurred. The thickness of the femoral and acetabular cartilage was estimated with a stereologic method. Three and one-half years postoperatively, 18 of 26 patients underwent MR arthrography to investigate if they had a torn acetabular labrum. RESULTS: The acetabular cartilage thickness differed between 1 and 2(1/2) years postoperatively (preoperative 1.40 mm, 1 year postoperatively 1.47 mm, and 2(1/2) years postoperatively 1.35 mm), but was similar at all times for the femoral cartilage (preoperative 1.38 mm, 1 year postoperatively 1.43 mm, and 2(1/2) years postoperatively 1.38 mm.) Seventeen of 18 patients had a torn labrum. The tears were located mainly superior on the acetabular rim. CONCLUSION: Cartilage thickness 2(1/2) years after surgery compared with preoperatively was unchanged indicating the osteoarthritis had not progressed during short-term followup after PAO.

AB - BACKGROUND: Untreated hip dysplasia can result in a degenerative process joint and secondary osteoarthritis at an early age. While most periacetabular osteotomies (PAOs) are performed to relieve symptoms, the osteotomy is presumed to slow or prevent degeneration unless irreparable damage to the cartilage has already occurred. QUESTIONS/PURPOSES: We therefore determined (1) whether changes in the thickness of the cartilage in the hip occur after PAO, and (2) how many patients had an acetabular labral tear and whether labral tears are associated with thinning of the cartilage after PAO. PATIENTS AND METHODS: We prospectively followed 22 women and four men with hip dysplasia with MRI before PAO and again 1 year and 2(1/2) years postoperatively to determine if cartilage thinning (reflecting osteoarthritis) occurred. The thickness of the femoral and acetabular cartilage was estimated with a stereologic method. Three and one-half years postoperatively, 18 of 26 patients underwent MR arthrography to investigate if they had a torn acetabular labrum. RESULTS: The acetabular cartilage thickness differed between 1 and 2(1/2) years postoperatively (preoperative 1.40 mm, 1 year postoperatively 1.47 mm, and 2(1/2) years postoperatively 1.35 mm), but was similar at all times for the femoral cartilage (preoperative 1.38 mm, 1 year postoperatively 1.43 mm, and 2(1/2) years postoperatively 1.38 mm.) Seventeen of 18 patients had a torn labrum. The tears were located mainly superior on the acetabular rim. CONCLUSION: Cartilage thickness 2(1/2) years after surgery compared with preoperatively was unchanged indicating the osteoarthritis had not progressed during short-term followup after PAO.

U2 - 10.1007/s11999-010-1310-z

DO - 10.1007/s11999-010-1310-z

M3 - Journal article

C2 - 20232180

JO - Clinical Orthopaedics and Related Research

JF - Clinical Orthopaedics and Related Research

SN - 0009-921X

ER -