Jens Peter Andersen

  1. 2019
  2. Published

    Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic. / Tadini-Buoninsegni, Francesco; Mikkelsen, Stine A; Mogensen, Louise S; Molday, Robert S.; Andersen, Jens Peter.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 33, 13.08.2019, p. 16332-16337.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. E-pub ahead of print

    Expression and Functional Characterization of Missense Mutations in ATP8A2 Linked to Severe Neurological Disorders. / Choi, Hanbin; Andersen, Jens P; Molday, Robert S.

    In: Human Mutation, 09.08.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. / Mikkelsen, Stine A; Mogensen, Louise S; Vilsen, Bente; Molday, Robert S; Vestergaard, Anna L; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 294, No. 15, 04.2019, p. 5970-5979.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. / Liou, Angela Y; Molday, Laurie L; Wang, Jiao; Andersen, Jens Peter; Molday, Robert S.

    In: Journal of Biological Chemistry, Vol. 294, No. 17, 04.2019, p. 6809-6821.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. / Roenn, Christian P; Li, Melody; Schack, Vivien R; Forster, Ian C; Holm, Rikke; Toustrup-Jensen, Mads S; Andersen, Jens P; Petrou, Steven; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 294, No. 1, 04.01.2019, p. 269-280.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Distinct effects of Q925 mutation on intracellular and extracellular Na+ and K+ binding to the Na+, K+-ATPase. / Nielsen, Hang N; Spontarelli, Kerri; Holm, Rikke; Andersen, Jens Peter; Einholm, Anja P.; Artigas, Pablo; Vilsen, Bente.

    In: Scientific Reports, Vol. 9, No. 1, 13344, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2018
  9. Published

    Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. / Wang, Jiao; Molday, Laurie L; Hii, Theresa; Coleman, Jonathan A; Wen, Tieqiao; Andersen, Jens P; Molday, Robert S.

    In: Scientific Reports, Vol. 8, No. 1, 17.07.2018, p. 10795.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. / Betzer, Cristine; Lassen, Louise Berkhoudt; Olsen, Anders; Kofoed, Rikke Hahn; Reimer, Lasse; Gregersen, Emil; Zheng, Jin; Calì, Tito; Gai, Wei-Ping; Chen, Tong; Moeller, Arne; Brini, Marisa; Fu, Yuhong; Halliday, Glenda; Brudek, Tomasz; Aznar, Susana; Pakkenberg, Bente; Andersen, Jens Peter; Jensen, Poul Henning.

    In: EMBO Reports, Vol. 19, No. 5, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b. / Mikkelsen, Stine A; Vangheluwe, Peter; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 293, 16.03.2018, p. 3880-3889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. 2017
  13. Published

    Dynamics of P-type ATPase transport cycle revealed by single-molecule FRET. / Dyla, Mateusz; Terry, Daniel; Kjærgaard, Magnus; Sørensen, Thomas Lykke-Møller; Andersen, Jacob Lauwring; Andersen, Jens Peter; Knudsen, Charlotte Rohde; Altman, Roger; Nissen, Poul; Blanchard, Scott.

    In: Nature, Vol. 551, No. 7680, 16.11.2017, p. 346-351.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Arginine replacement of Cys932 converts Na,K-ATPase to an electroneutral pump. Poster presented by Rikke Holm at the 15th International Conference on Na,K-ATPase and related Transport ATPases, Otsu, Japan, 2017. / Jensen, Rikke Holm; Khandelwal, Jaanki; Einholm, Anja P.; Andersen, Jens Peter; Artigas, Pablo; Vilsen, Bente.

    2017. Poster session presented at The 15th International Conference on Na,K-ATPase and related transport ATPases, Japan.

    Research output: Contribution to conferencePosterResearch

  15. Published
  16. Published
  17. Published
  18. Published

    Towards the structure of yeast and mammalian P4-ATPases : Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017. / Lyons, Joseph; Laban, Milena; Mikkelsen, Stine; Ulstrup, Jakob; Mogensen, Louise S; Montigny, Cédric; Ash, Miriam-Rose; Molday, Robert S.; Frauenfeld, Jens; Andersen, Jens Peter; Lenoir, Guillaume; Nissen, Poul.

    2017.

    Research output: Contribution to conferencePosterResearch

  19. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATE SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne; Olsen, Anders; Kofoed, Rikke Hahn; Zheng, Jin; Cali, Tito; Brini, Marisa; Gai, Wei-Ping; Andersen, Jens Peter; Jensen, Poul Henning.

    2017. Poster session presented at 20 years of alpha-synuclein in Parkinson's disease and related synucleinopathies, Greece.

    Research output: Contribution to conferencePosterResearch

  20. Published

    Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates. / Gantzel, Rasmus H; Mogensen, Louise S; Mikkelsen, Stine A; Vilsen, Bente; Molday, Robert S; Vestergaard, Anna L; Andersen, Jens P.

    In: Scientific Reports, Vol. 7, No. 1, doi: 10.1038/s41598-017-10741-z., 05.09.2017, p. 10418.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATES SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne; Kofoed, Rikke Hahn; Zheng, Jin; Calì, Tito; Brini, Marisa; Gai, Wei Ping; Andersen, Jens Peter; Jensen, Poul Henning.

    2017. Poster session presented at AD/PD 2017 , Vienna, Austria.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase. / Holm, Rikke ; Khandelwal, J; Einholm, Anja P.; Andersen, Jens Peter; Artigas, Pablo; Vilsen, Bente.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 2, 10.01.2017, p. 316-321.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. 2016
  24. Published

    Neurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function. / Holm, Rikke ; Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien; Andersen, Jens Peter; Vilsen, Bente.

    In: B B A - Bioenergetics, Vol. 1857, No. 11, 11.2016, p. 1807–1828.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  25. Published

    Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis. / van der Woerd, Wendy L; Wichers, Catharina G K; Vestergaard, Anna L; Andersen, Jens Peter; Paulusma, Coen C; Houwen, Roderick H J; van de Graaf, Stan F J.

    In: Journal of Hepatology, Vol. 64, No. 6, 06.2016, p. 1339-47.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand Jean-Paul; Olesen, Claus; Andersen, Jens Peter; Møller, Jesper Vuust; Nissen, Poul.

    In: Structure, Vol. 24, No. 4, 05.04.2016, p. 617-623.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published
  28. Published

    Determination of the ATP Affinity of the Sarcoplasmic Reticulum Ca(2+)-ATPase by Competitive Inhibition of [γ-(32)P]TNP-8N3-ATP Photolabeling. / Clausen, Johannes D; McIntosh, David B; Woolley, David G; Andersen, Jens Peter.

    In: Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, p. 233-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Review: P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas. / Andersen, Jens P; Vestergaard, Anna L; Mikkelsen, Stine A; Mogensen, Louise S; Chalat, Madhavan; Molday, Robert S.

    In: Frontiers in Physiology, Vol. 7, 2016, p. 275 (23 pages).

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2015
  31. Published

    Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit. / Vestergaard, Anna L; Mikkelsen, Stine A; Coleman, Jonathan A; Molday, Robert S; Vilsen, Bente; Andersen, Jens Peter.

    In: FEBS Letters, Vol. 589, 22.11.2015, p. 3908-3914.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Biochemical characterization of P4-ATPase mutations associated with Intrahepatic Cholestatic Disease. / Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Molday, Robert S.; Andersen, Jens Peter.

    2015. Abstract from Scandinavian Physiological Society Annual Meeting, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  33. Published

    Analysis of amino acid residues of potential importance for phosphatidylserine specificity of P4-type ATPase ARP8A2. / Mogensen, Louise; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2015. Poster session presented at 4th International Workshop on Expression, Structure and Function of Membrane Proteins, Firenze, Italy.

    Research output: Contribution to conferencePosterResearch

  34. Published

    Scanning mutagenesis of transmembrane segments M5 and M6 of the mammalian flippase ATP8A2 – evidence for a classic transport pathway? / Mikkelsen, Stine; Vestergaard, Anna Lindeløv; Coleman, Jonathan Allan; Vilsen, Bente; S. Molday, Robert; Andersen, Jens Peter.

    2015.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Rescue of Na+ affinity in aspartate 928 mutants of Na+,K+-ATPase by secondary mutation of glutamate 314. / Holm, Rikke; Einholm, Anja P; Andersen, Jens P; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 290, No. 15, 10.04.2015, p. 9801-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease. / Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; S. Molday, Robert; Andersen, Jens Peter.

    2015. Poster session presented at 4th International Workshop on Expression, Structure and Function of Membrane Proteins, Firenze, Italy.

    Research output: Contribution to conferencePosterResearch

  37. 2014
  38. Published

    Critical Roles of Interdomain Interactions for Modulatory ATP Binding to Sarcoplasmic Reticulum Ca2+-ATPase. / Clausen, Johannes D; Holdensen, Anne Nyholm; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, 05.09.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease. / Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien; Nielsen, Hang Nguyen; Holm, Rikke; Sobrido, Maria-Jesus; Andersen, Jens Peter; Clausen, Torben; Vilsen, Bente.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  40. Published

    Rescue of Na+ and H+ binding in Na+,K+-ATPase M8 aspartate mutants by secondary mutation. / Holm, Rikke; Einholm, Anja P.; Andersen, Jens Peter; Vilsen, Bente.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  41. Published

    Analysis of Amino Acid Residues of Potential Importance for Phosphati-dylserine Specificity of P4-type ATPase ATP8A2. / Mogensen, Louise; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  42. Published

    Darier disease mutation E917K of SERCA2b relieves the inhibitory influence of the 11th transmembrane segment. / Mikkelsen, Stine; Holdensen, Anne Nyholm; Vangheluwe, Peter; Vilsen, Bente; Andersen, Jens Peter.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  43. Published

    Stability cluster links hydrofobic gate to K873 in ATP8A2. / Mikkelsen, Stine; Vestergaard, Anna Lindeløv; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session presented at 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  44. Published

    Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2. / Vestergaard, Anna L; Coleman, Jonathan A; Lemmin, Thomas; Mikkelsen, Stine A; Molday, Laurie L; Vilsen, Bente; Molday, Robert S; Dal Peraro, Matteo; Andersen, Jens Peter.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 14, 08.04.2014, p. E1334-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease. / Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien; Nielsen, Hang Nguyen; Holm, Rikke; Sobrido, María-Jesús; Andersen, Jens Peter; Clausen, Torben; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 289(6), 07.02.2014, p. 3186-3197.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease. / Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session presented at Na,K-ATPase and related transport ATPases, structure, mechanism, cell biology, health and disease, Lunteren, Netherlands.

    Research output: Contribution to conferencePosterResearch

  47. Published
  48. 2013
  49. Published

    SERCA mutant E309Q binds two Ca ions but adopts a catalytically incompetent conformation. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand; Montigny, Cédric; Jaxel, Christine; Møller, Jesper Vuust; Nissen, Poul; Andersen, Jens Peter; le Maire, Marc.

    In: E M B O Journal, Vol. 32, No. 24, 11.12.2013, p. 3231-3243.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published
  51. Published
  52. Published
  53. 2012
  54. Published

    Distinct Roles of the C-terminal 11th Transmembrane Helix and Luminal Extension in the Partial Reactions Determining the High Ca2+ Affinity of Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2b (SERCA2b). / Clausen, Johannes D; Vandecaetsbeek, Ilse; Wuytack, Frank; Vangheluwe, Peter; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 287, No. 47, 28.09.2012, p. 39460-39469.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Na+,K+-ATPase amino acids involved in transport of the 3rd sodium ion. / Holm, Rikke; Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Andersen, Jens Peter; Vilsen, Bente.

    2012. Poster session presented at 3rd International Workshop on Expression, Structure and Function of Membrane Proteins, Florence, Italy.

    Research output: Contribution to conferencePosterResearch

  56. Published

    Flip i cellemembranen. / Vestergaard, Anna Lindeløv; Vilsen, Bente; Andersen, Jens Peter.

    In: Aktuel Naturvidenskab, Vol. 2012-2, 09.05.2012, p. 18-19.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  57. Published

    Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2. / Coleman, Jonathan A; Vestergaard, Anna L; Molday, Robert S; Vilsen, Bente; Andersen, Jens Peter.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 5, 31.01.2012, p. 1449-54.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Coarse-Grained Simulations of Transitions in the E2-to-E1 Conformations for Ca ATPase (SERCA) Show Entropy-Enthalpy Compensation. / Nagarajan, Anu; Andersen, Jens Peter; Woolf, Thomas B.

    In: Journal of Molecular Biology, Vol. 422, No. 4, 2012, p. 575-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Functional impacts of the Darier Disease mutation E917K/E918K and addition of two different tails to SERCA. / Mikkelsen, Stine; Holdensen, Anne Nyholm; Vilsen, Bente; Andersen, Jens Peter.

    2012. Poster session presented at 3rd International Workshop on Expression, Structure and Function of Membrane Proteins , Florence, Italy.

    Research output: Contribution to conferencePosterResearch

  60. Published
  61. Published

    The role of domain-domain interactions versus domain-water interactions in the coarse-grained simulations of the E1P to E2P transitions in Ca-ATPase (SERCA). / Nagarajan, Anu; Andersen, Jens Peter; Woolf, Thomas B.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 80, No. 8, 2012, p. 1929-47.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published
  63. 2011
  64. Published

    Characterization of the P4-ATPase ATP8A2: Critical Roles of Key Residues in the Fourth Transmembrane Segment in Aminophospholipid Transport : Poster for the 13th international ATPase conference, Pacific Grove, CA, USA. / Vestergaard, Anna Lindeløv; Coleman, Jonathan A.; Molday, Robert S.; Vilsen, Bente; Andersen, Jens Peter.

    2011. Poster session presented at 13th International ATPase conference, .

    Research output: Contribution to conferencePosterResearch

  65. Published
  66. Published

    Characterization of the P4-ATPase ATP8A2: Identification of Key Residues Involved in Catalysis and Lipid Transport : Poster for the 13th international ATPase conference, Pacific Grove, CA, USA. / Coleman, Jonathan Allan; Vestergaard, Anna Lindeløv; Molday, Robert S.; Vilsen, Bente; Andersen, Jens Peter.

    2011. Poster session presented at 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, United States.

    Research output: Contribution to conferencePosterResearch

  67. Published

    A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. / Morth, Jens Preben; Pedersen, Bjørn Panella; Buch-Pedersen, Morten Jeppe; Andersen, Jens Peter; Vilsen, Bente; Palmgren, Michael G; Nissen, Poul.

    In: Nature Reviews. Molecular Cell Biology, Vol. 12, 01.2011, p. 60-70.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    Modulatory ATP binding affinity in intermediate states of E2P dephosphorylation of sarcoplasmic reticulum Ca2+-ATPase. / Clausen, Johannes D.; McIntosh, David B.; Woolley, David G.; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 286, No. 13, 2011, p. 11792-11802.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Na+,K+-ATPase amino acids involved in transport of the 3rd sodium ion. / Holm, Rikke; Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Andersen, Jens Peter; Vilsen, Bente.

    2011. Poster session presented at 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, United States.

    Research output: Contribution to conferencePosterResearch

  70. Published

    The rapid-onset dystonia parkinsonism mutation D923N of the Na+,K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site and leads to a rise in intracellular Na+ in cell cultur. / Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Holm, Rikke; Andersen, Jens Peter; Vilsen, Bente.

    2011. Poster session presented at 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, United States.

    Research output: Contribution to conferencePosterResearch

  71. 2010
  72. Published

    Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins. / Cardi, Delphine; Pozza, Alexandre; Arnou, Bertrand; Marchal, Estelle Lucette; Clausen, Johannes D.; Andersen, Jens Peter; Krishna, Sanjeev; Møller, Jesper Vuust; le Maire, Marc; Jaxel, Christine.

    In: Journal of Biological Chemistry, Vol. 285, No. 34, 20.10.2010, p. 26406-26416.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    The rapid-onset dystonia Parkinsonism mutation D923N of the Na+,K+-ATPase alpha-3 isoform disrupts Na+interaction at the third Na+ site. / Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Holm, Rikke; Andersen, Jens Peter; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 285, No. 34, 20.08.2010, p. 26245-26254.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Glutamate 90 at the Luminal Ion Gate of Sarcoplasmic Reticulum Ca2+-ATPase Is Critical for Ca2+ Binding on Both Sides of the Membrane. / Clausen, Johannes D.; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 285, No. 27, 02.07.2010, p. 20780-20792.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    A Combined Zinc/Cadmium Sensor and Zinc/Cadmium Export Regulator in a Heavy Metal Pump. / Bækgaard, Lone; Mikkelsen, Maria D. ; Sørensen, Danny M.; Hegelund, Josefine N.; Persson, Daniel P.; Mills, Rebecca F.; Yang, Zhang; Husted, Søren ; Andersen, Jens Peter; Buch-Pedersen, Morten J.; Schjoerring, Jan K.; Williams, Lorraine E.; Palmgren, Michael G.

    In: Journal of Biological Chemistry, Vol. 285, No. 41, 2010, p. 31243-31252.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published
  77. 2009
  78. Published

    The length of the A-M3 linker is a crucial determinant of the rate of the Ca2+ transport cycle of sarcoplasmic reticulum Ca2+-ATPase. / Holdensen, Anne Nyholm; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 284, No. 18, 01.05.2009, p. 12258-12265.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    A-M3 Linker Length is a Crucial Determinant of the Ca2+ Transport Cycle Rate of Sarcoplasmic Reticulum Ca2+-ATPase. / Holdensen, Anne Nyholm; Andersen, Jens Peter.

    2009. Poster session presented at 2nd International Workshop on Expression, Structure and Function on Membrane Proteins20.–24., Florence, Italy.

    Research output: Contribution to conferencePosterResearch

  80. Published

    Calcium Pump, Chemistry of. / Anthonisen, Anne Nyholm; Andersen, Jens Peter.

    WILEY ENCYCLOPEDIA OF CHEMICAL BIOLOGY. Vol. 1 1. ed. John Wiley & Sons Ltd, 2009. p. 212-218.

    Research output: Contribution to book/anthology/report/proceedingEncyclopedia entryResearch

  81. Published

    Crystal Structure of a type IIC P-type ATPase. / Morth, Jens Preben (Inventor); Andersen, Jens Peter (Inventor); Vilsen, Bente (Inventor); Nissen, Poul (Inventor).

    Patent No.: PCT/DK2008/050307. Dec 12, 2008.

    Research output: PatentResearch

  82. Published

    P-type ATPases as drug targets: Tools for medicine and science. / Yatime, Laure; Buch-Pedersen, Morten Jeppe; Musgaard, Maria; Morth, Jens Preben; Winther, Anne-Marie Lund; Pedersen, Bjørn Panyella; Olesen, Claus Elsborg; Andersen, Jens Peter; Vilsen, Bente; Schiøtt, Hanne Birgit; Palmgren, Michael; Møller, Jesper Vuust; Nissen, Poul; Fedosova, Natalya.

    In: B B A - Bioenergetics, Vol. 1787, No. 4, 2009, p. 207-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    The C Terminus of Na+,K+-ATPase Controls Na+ Affinity on Both Sides of the Membrane through Arg935. / Toustrup-Jensen, Mads Schak; Holm, Rikke; Einholm, Anja P.; Schack, Vivien Rodacker; Morth, Jens Preben; Nissen, Poul; Andersen, Jens Peter; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 284, No. 28, 2009, p. 18715-18725.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. / Morth, J Preben; Poulsen, Hanne; Toustrup-Jensen, Mads S; Schack, Vivien Rodacker; Egebjerg, Jan; Andersen, Jens Peter; Vilsen, Bente; Nissen, Poul.

    In: Royal Society of London. Philosophical Transactions. Biological Sciences, Vol. 364, No. 1514, 2009, p. 217-27.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. 2008
  86. Published

    Critical Interaction of Actuator Domain Residues Arginine 174, Isoleucine 188, and Lysine 205 with Modulatory Nucleotide in Sarcoplasmic Reticulum Ca2+-ATPase. / Clausen, Johannes D.; McIntosh, David B; Woolley, David G; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 283, No. 51, 2008, p. 35703-14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Crystal Structure of D351A and P312A Mutant Forms of the Mammalian Sarcoplasmic Reticulum Ca2+-ATPase Reveals Key Events in Phosphorylation and Ca2+ Release. / Marchand, Alexandre; Winther, Anne-Marie Lund; Holm, Peter; Olesen, Claus; Montigny, Cedric; Arnou, Bertrand; Champeil, Philippe; Clausen, Johannes D.; Vilsen, Bente; Andersen, Jens Peter; Nissen, Poul; Jaxel, Christine; Møller, Jesper Vuust; le Maire, Marc.

    In: Journal of Biological Chemistry, Vol. 283, No. 21, 2008, p. 14867-14882.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Identification and function of a cytoplasmic K+ site of the Na+,K+-ATPase. / Schack, Vivien Rodacker; Morth, Jens Preben; Toustrup-Jensen, Mads Schak; Anthonisen, Anne Nyholm; Nissen, Poul; Andersen, Jens Peter; Vilsen, Bente.

    2008. Poster session presented at 12th International ATPase Conference:  Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  89. Published

    Identification and function of a cytoplasmic K+ site of the Na+,K+ATPase. / Schack, Vivien Rodacker; Morth, Jens Preben; Toustrup-Jensen, Mads S; Anthonisen, Anne Nyholm; Nissen, Poul; Andersen, Jens Peter; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 283, No. 41, 2008, p. 27982-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  90. Published

    Importance of A-M3 Linker Length for Ca2E1P-E2P Conformational Transition of Sarcoplasmic Reticulum Ca2+-ATPase. / Holdensen, Anne Nyholm; Andersen, Jens Peter.

    2008. Poster session presented at PUMPkin annual meeting, 2008, Denmark.

    Research output: Contribution to conferencePosterResearch

  91. Published

    Importance of A-M3 linker length for Ca2E1P-E2P conformational transition of sarcoplasmic reticulum Ca2+-ATPase. / Holdensen, Anne Nyholm; Andersen, Jens Peter.

    2008. Poster session presented at 12th International ATPase Conference: Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  92. Published

    Importance of Ser938 for Na+ binding to Na+,K+-ATPase. / Einholm, Anja P.; Jensen, Rikke Holm; Toustrup-Jensen, Mads Schak; Andersen, Jens Peter; Vilsen, Bente.

    2008. Poster session presented at 12th International ATPase Conference: Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease., Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  93. Published

    Insertion of Gly/Pro loops in the A-M3 Linker of SR Ca2+-ATPase – Importance of Linker Length in Movement of the A Domain. / Holdensen, Anne Nyholm; Andersen, Jens Peter.

    2008. Poster session presented at PhD day 2008, Faculty of Health Sciences, AU, Denmark.

    Research output: Contribution to conferencePosterResearch

  94. Published

    Involvement of the actuator domain of sarcoplasmic reticulum Ca2+-ATPase in modulatory modes of ATP binding. / Clausen, Johannes D.; McIntosh, David B.; Woolley, David G.; Andersen, Jens Peter.

    2008. Poster session presented at   12th International ATPase Conference: Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  95. 2007
  96. Published

    ATP-binding Modes and Functionally Important Interdomain Bonds of Sarcoplasmic Reticulum Ca2+-ATPase Revealed by Mutation of Glycine 438, Glutamate 439, and Arginine 678. / Clausen, Johannes D.; McIntosh, David B.; Anthonisen, Anne Nyholm; Woolley, David G.; Vilsen, Bente; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 282, No. 28, 2007, p. 20686-20697.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  97. Published

    Crystal structure of the sodium-potassium pump. / Morth, J Preben; Pedersen, Bjørn Panyella; Toustrup-Jensen, Mads S; Sørensen, Thomas L-M; Petersen, Janne; Andersen, Jens Peter; Vilsen, Bente; Nissen, Poul.

    In: Nature, Vol. 450, No. 7172, 2007, p. 1043-1049.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. Published

    Importance of Leu99 in transmembrane segment M1 of the Na+, K+ -ATPase in the binding and occlusion of K+. / Einholm, Anja P.; Andersen, Jens Peter; Vilsen, Bente.

    In: Journal of Biological Chemistry, Vol. 282, No. 33, 2007, p. 23854-23866.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    Roles of transmembrane segment M1 of Na(+),K (+)-ATPase and Ca (2+)-ATPase, the gatekeeper and the pivot. / Einholm, Anja P.; Andersen, Jens Peter; Vilsen, Bente.

    In: Journal of Bioenergetics and Biomembranes, Vol. 39, No. 5-6, 2007, p. 357-366.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  100. Published

     Insertions of Gly/Pro Loops in the A-M3 Linker of SR Ca2+-ATPase - Importance of Linker Length in Movement of the A Domain. / Anthonisen, Anne Nyholm; Andersen, Jens Peter.

    2007. Poster session presented at  Membrane Protein Isolation, Crystallization and Structure Determination (TRAMP-6 Symposium), PUMPkin, Denmark.

    Research output: Contribution to conferencePosterResearch

  101. 2006
  102. Published

    Asparagine 706 and glutamate 183 at the catalytic site of sarcoplasmic reticulum Ca2+-ATPase play critical but distinct roles in E2 states. / Clausen, Johannes D.; McIntosh, David B.; Woolley, David G.; Anthonisen, Anne Nyholm; Vilsen, Bente; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 281, 2006, p. 9471-9481.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  103. Published

    Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c). / Dally, Saoussen; Bredoux, Raymonde; Corvazier, Elisabeth; Andersen, Jens Peter; Clausen, Johannes D.; Dode, Leonard; Fanchaouy, Mohammed; Gelebart, Pascal; Monceau, Virginie; del Monte, Frederica; Gwathmey, Judith K.; Hajjar, Roger; Chaabane, Chiraz; Bobe, Régis; Raies, Aly; Enouf, Jocelyne.

    In: Biochemical Journal, Vol. 395, 2006, p. 249–258.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. Published

    Mutational analysis of the conserved TGES loop of sarcoplasmic reticulum Ca2+-ATPase. / Anthonisen, Anne Nyholm; Clausen, Johannes D.; Andersen, Jens Peter.

    In: Journal of Biological Chemistry, Vol. 281, 2006, p. 31572-31582.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  105. 2005
  106. Published

    Functional Comparison between Secretory Pathway Ca2+/Mn2+-ATPase (SPCA) 1 and Sarcoplasmic Reticulum Ca2+-ATPase (SERCA) 1 Isoforms by Steady-state and Transient Kinetic Analyses. / Dode, L.; Andersen, Jens Peter; Raeymaekers, L.; Missiaen, L.; Vilsen, Bente; Wuytack, F.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 39124-39134.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. Published

    Mutation of Gly-94 in transmembrane segment M1 of Na+, K+-ATPase interferes with Na+ and K+ binding in E2P conformation. / Einholm, Anja P.; Jensen, Mads Toustrup; Andersen, Jens Peter; Vilsen, Bente.

    In: Proceedings of the National Academy of Science, USA, Vol. 102, 2005, p. 11254-11259.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. 2004
  109. Published

    Functional consequences of alterations to Thr247, Pro248, Glu 340, Asp813, Arg819, and Arg822, at the interfaces between domain P, M3, and L6-7 of sarcoplasmic reticulum Ca2+-ATPase: Roles in Ca2+ interaction and phosphoenzyme processing. / Clausen, J.D.; Andersen, J.P.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 54426-54437.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  110. Published

    Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions. / Clausen, J.D.; Vilsen, B.; McIntosh, D.B.; Einholm, A.P.; Andersen, J.P.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, 2004, p. 2776-2781.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  111. Published

    Identification, expression, function, and localization of a novel (sixth) isoform of the human sarco/endoplasmic reticulum Ca2+-ATPase 3 gene. / Bobe, R.; Bredoux, R.; Corvazier, E.; Andersen, J.P.; Clausen, J.D.; Dode, L.; Enouf, J.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 24297-24306.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  112. Published

    Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing. / Einholm, A.P.; Vilsen, B.; Andersen, J.P.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 15888-15896.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  113. Published

    Localization of a K+-binding Site Involved in Dephosphorylation of the Sarcoplasmic Reticulum Ca2+-ATPase. / Sørensen, Thomas Lykke-Møller; Clausen, Johannes D.; Jensen, A.-M., L.; Vilsen, Bente; Møller, J.V.; Andersen, Jens Peter; Nissen, Poul.

    In: Journal of Biological Chemistry, Vol. 279, No. 45, 2004, p. 46355-46358.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  114. Published

    Roles of conserved P-domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase. / McIntosh, D.B.; Clausen, J.D.; Woolley, D.G.; MacLennan, D.H.; Vilsen, B.; Andersen, J.P.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 32515-32523.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  115. 2003
  116. Published

    ATP binding residues of sarcoplasmic reticulum Ca2+-ATPase. / McIntosh, D.B.; Clausen, J.D.; Woolley, D.G.; MacLennan, D.H.; Vilsen, B.; Andersen, J.P.

    In: New York Academy of Sciences. Annals, Vol. 986, 2003, p. 101-105.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  117. Published

    Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transientkinetic analyses. / Dode, L.; Andersen, J.P.; Leslie, N.; Dhitavat, J.; Vilsen, B.; Hovnanian, A.

    In: Journal of Biological Chemistry, Vol. 278, 2003, p. 47877-47889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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