Jens Peter Andersen

Professor

 

FULL LIST OF INTERNATIONAL PUBLICATIONS BY JENS PETER ANDERSEN 2018

By September 2018 a total of 144 papers on molecular structure, mechanism, and pathophysiology of ion pumps and channels: 115 peer reviewed journal articles (A), 29 articles in non-peer reviewed books and conference proceedings (B). 55 articles in J Biol Chem, 6 in Proc Natl Acad Sci USA, 2 in Nature, 3 in other Nature series. 28 first and sole authorships. 90 corresponding authorships. Citations: 5087 (4293 without self citations). H-index 43 (by September 2018, Web of Science, all databases).

 

A. Peer reviewed journal articles

+ = corresponding authorship

 

115. Wang, J., Molday, L.L., Hii, T., Coleman, J.A., Wen, T., Andersen, J.P., Molday, R.S.+ 2018

Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues.

Scientific Reports 8:10795 (14 pages)

 

114. Betzer, C., Lassen, L.B., Olsen, A., Kofoed, R.H., Reimer, L., Gregersen, E., Zheng, J., Calì, T., Gai, W.P., Chen, T., Moeller, A., Brini, M., Fu, Y., Halliday, G., Brudek, T., Aznar, S., Pakkenberg, B., Andersen, J.P., Jensen, P.H.+ 2018

Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.

EMBO Reports 19:e44617 (21 pages)

 

113. Mikkelsen, S.A., Vangheluwe, P., Andersen, J.P.+ 2018

A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b.

The Journal of Biological Chemistry 293:3880-3889

Highlighted as one of Editor’s picks

 

112. Dyla, M., Terry, D.S., Kjaergaard, M., Sørensen, T.L., Lauwring Andersen, J. Andersen, J.P., Rohde Knudsen, C., Altman, R.B., Nissen, P.+, Blanchard, S.C.+ 2017

Dynamics of P-type ATPase transport revealed by single-molecule FRET.

Nature 551:346-351

 

111. Gantzel, R.H., Mogensen, L.S., Mikkelsen, S.A., Vilsen, B., Molday, R.S., Vestergaard, A.L., Andersen, J.P.+ 2017

Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates.

Scientific Reports 7:10418 (11 pages)

 

110. Holm, R., Khandelwal, J., Einholm, A.P., Andersen, J.P., Artigas, P., Vilsen, B.+ 2017

Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase.

Proceedings of the National Academy of Sciences U.S.A. 114:316-321

 

109. Holm, R., Toustrup-Jensen, M.S., Schack, V., Andersen, J.P., Vilsen, B.+ 2016

Neurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function. Review.

Biochimica et Biophysica Acta - Bioenergetics 1857:1807-1828

 

108. Andersen, J.P., Vestergaard, A.L., Mikkelsen, S.A., Mogensen, L.S., Chalat, M., Molday, R.S.+ 2016

P4-ATPases as Phospholipid Flippases - Structure, Function, and Enigmas. Review.

Frontiers in Physiology, 7:275 (23 pages)

 

107. van der Woerd, W.L, Wichers, C.G.K., Vestergaard, A.L., Andersen, J.P., Paulusma, C.C. Houwen, R.H.J., van de Graaf, S.F.J.+ 2016

Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis.

Journal of Hepatology 64:1339-1347

 

106. Clausen, J.D., Bublitz, M., Arnou, B. J.-P., Olesen, C., Andersen, J.P., Møller, J.V., Nissen, P.+ 2016

Crystal structure of the vanadate-inhibited Ca2+-ATPase.

Structure 24:617-623

 

105. Vestergaard, A.L.+, Mikkelsen, S.A., Coleman, J.A., Molday, R.S., Vilsen, B., Andersen, J.P. 2015

Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit.

FEBS Letters 589:3908-3914

 

104. Holm, R., Einholm, A.P., Andersen, J.P., Vilsen, B+ 2015

Rescue of Na+ affinity in aspartate-928 mutants of Na+,K+-ATPase by secondary mutation of glutamate-314.

The Journal of Biological Chemistry 290:9801-9811

 

103. Clausen, J.D., Holdensen, A.N., Andersen, J.P.+ 2014

Critical roles of interdomain interactions for modulatory ATP binding to sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 289:29123-29134

 

102. Vestergaard, A.L., Coleman, J.A., Lemmin, T., Mikkelsen, S.A., Molday, L.L., Vilsen, B., Molday, R.S., Dal Peraro, M., Andersen, J.P.+ 2014

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.

Proceedings of the National Academy of Sciences U.S.A. 111:E1334-E1343

Research Highlight in Nature Chemical Biology 2014 10:409

 

101. Toustrup-Jensen, M.S., Einholm, A.P., Nielsen, H.N., Holm, R., Sobrido, M.-J., Andersen, J.P., Clausen, T., Vilsen, B.+ 2014

Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.

The Journal of Biological Chemistry 289:3186-3197

 

100. Clausen, J.D., Bublitz, M., Arnou, B., Montigny, C., Jaxel, C, Møller, J.V., Nissen, P.+, Andersen, J.P.+, le Maire, M.+ 2013

SERCA mutant E309Q binds two Ca2+ ions but adopts a catalytically incompetent conformation.

EMBO Journal 32:3231-3243

 

99. Clausen, J.D., Vandecaetsbeek, I., Wuytack. F., Vangheluwe, P., Andersen, J.P.+ 2012

Distinct roles of the C-terminal 11th transmembrane helix and luminal extension in the partial reactions determining the high Ca2+ affinity of sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2b (SERCA2b).

The Journal of Biological Chemistry 287:39460-39469

 

98. Nagarajan, A., Andersen, J.P., Woolf, T.B.+ 2012

Coarse-grained simulations of transitions in the E2-to-E1 conformations for Ca ATPase (SERCA) show entropy-enthalpy compensation.

Journal of Molecular Biology 422:575-593

 

97. Nagarajan, A., Andersen, J.P., Woolf, T.B.+ 2012

The role of domain:domain interactions versus domain:water interactions in the coarse-grained simulations of the E1P to E2P transitions in Ca-ATPase (SERCA).

Proteins 80:1929-1947

 

96. Coleman, J.A., Vestergaard, A.L., Molday, R.S.,Vilsen, B., Andersen, J.P.+ 2012

Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2.

Proceedings of the National Academy of Sciences U.S.A. 109:1449-1454

 

95. Clausen, J.D., McIntosh, D.B., Woolley, D.G., Andersen, J.P.+ 2011

Modulatory ATP binding affinity in intermediate states of E2P dephosphorylation of sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 286:11792-11802

 

94.Morth, J.P., Pedersen, B.P., Buch-Pedersen, M.J., Andersen, J.P., Vilsen, B., Palmgren, M.G., Nissen, P.+ 2011

A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. Review.

Nature Reviews Molecular Cell Biology 12:60-70

 

93. Baekgaard, L., Mikkelsen, M.D., Sørensen, D.M., Hegelund, J.N., Persson, D.P., Mills, R.F., Yang, Z., Husted, S., Andersen, J.P., Buch-Pedersen, M.J., Schjoerring, J.K., Williams, L.E., Palmgren, M.G.+ 2010

A combined zinc/cadmium sensor and zinc/cadmium export regulator in a heavy metal pump.

The Journal of Biological Chemistry, 285:31243-31252

 

92.Einholm, A.P., Toustrup-Jensen, M.S., Holm, R., Andersen, J.P., Vilsen, B+. 2010

The rapid-onset dystonia parkinsonism mutation D923N of the Na+,K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site.

The Journal of Biological Chemistry, 285:26245-26254

 

91.Cardi, D., Pozza, A., Arnou, B., Marchal, E., Clausen, J.D., Andersen, J.P., Krishna, S., Møller, J.V., le Maire, M.+, Jaxel, C+. 2010

Purified E255L mutant SERCA1a and purified PfATP6 are sensitive to SERCA-type inhibitors but insensitive to artemisinins.

The Journal of Biological Chemistry 285:26406-26416

 

90.Clausen, J.D., Andersen, J.P.+ 2010
Glutamate 90 at the luminal ion gate of sarcoplasmic reticulum Ca2+-ATPase is critical for Ca2+ binding on both sides of the membrane.

The Journal of Biological Chemistry 285:20780-20792

 

89.Toustrup-Jensen, M.S., Holm, R., Einholm, A.P., Schack, V.R., Morth, J.P., Nissen, P., Andersen, J.P., Vilsen, B.+ 2009

The C-terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.

The Journal of Biological Chemistry 284:18715-18725.

Selected as JBC Paper of the Week.

 

88. Yatime, L., Buch-Pedersen, M.J., Musgaard, M., Morth, J.P., Lund Winther, A.M., Pedersen, B.P., Olesen, C., Andersen, J.P., Vilsen, B., Schiøtt. B., Palmgren, M.G., Møller, J.V., Nissen, P.+, Fedosova, N. 2009

P-type ATPases as drug targets: tools for medicine and science. Review.

Biochimica et Biophysica Acta. 1787:207-220

 

87. Holdensen, A. N., Andersen, J. P.+ 2009

The length of the A-M3 Linker is a crucial determinant of the rate of the Ca2+ transport cycle of sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 284:12258-12265

Selected as JBC Paper of the Week.

 

86. Morth, J.P., Poulsen, H., Toustrup-Jensen, M.S., Schack, V.R., Egebjerg, J., Andersen, J.P., Vilsen, B., Nissen, P.+ 2009

The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations

Philosophical Transactions of the Royal Society London B Biological Sciences 364:217-227

 

85. Clausen, J.D., McIntosh, D.B., Woolley, D.G., Andersen, J.P.+ 2008

Critical interaction of actuator domain residues arginine 174, isoleucine 188, and lysine 205 with modulatory nucleotide in sarcoplasmic reticulum Ca2+-ATPase

The Journal of Biological Chemistry 283:35703-35714

 

84. Schack, V.R., Morth, J.P., Toustrup-Jensen, M.S., Anthonisen, A.N., Nissen, P., Andersen, J.P., Vilsen, B.+ 2008

Identification and function of a cytoplasmic K+ site of the Na+,K+-ATPase.

The Journal of Biological Chemistry 283:27982-27990

 

83. Marchand, A., Winther, A.-M.L., Holm, P.J., Olesen, C., Montigny, C., Arnou, B., Champeil, P., Clausen, J.D., Vilsen, B., Andersen, J.P., Nissen, P.+, Jaxel, C.+, Møller, J.V.+, le Maire, M.+ 2008.

Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca2+-ATPase reveals key events in phosphorylation and Ca2+ release.

The Journal of Biological Chemistry 283:14867-14882

 

82. Morth, J.P., Pedersen, B.P., Toustrup-Jensen, M.S., Sørensen, T.L, Petersen, J., Andersen, J.P., Vilsen, B.+, and Nissen, P.+ 2007

Crystal structure of the sodium-potassium pump.

Nature 450:1043-1049 (“Article”) + cover of this issue

Selected as favourite structural biology paper in Nature 2007

 

81. Einholm, A.P., Andersen, J.P., Vilsen, B.+ 2007

Roles of transmembrane segment M1 of Na+,K+-ATPase and Ca2+-ATPase, the gatekeeper and the pivot. Review.

Journal of Bioenergetics and Biomembranes 39:357-366

 

80. Einholm, A.P., Andersen, J.P., Vilsen, B.+ 2007

Importance of Leu99 in transmembrane segment M1 of the Na+,K+-ATPase in the binding and occlusion of K+

The Journal of Biological Chemistry 282:23854-23866.

 

79. Clausen, J.D., McIntosh, D.B., Anthonisen, A.N., Woolley, D.G., Vilsen, B, Andersen, J.P.+ 2007

ATP-binding modes and functionally important interdomain bonds of sarcoplasmic reticulum Ca2+-ATPase revealed by mutation of glycine 438, glutamate 439, and arginine 678

The Journal of Biological Chemistry 282:20686-20697

 

78. Anthonisen, A.N., Clausen, J.D., Andersen, J.P.+ 2006

Mutational analysis of the conserved TGES loop of sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 281:31572-31582

 

77. Clausen, J.D., McIntosh, D.B., Woolley, D.G., Anthonisen, A.N., Vilsen, B., Andersen, J.P.+ 2006

Asparagine-706 and glutamate-183 at the catalytic site of sarcoplasmic reticulum Ca2+-ATPase play critical but distinct roles in E2/E2P states

The Journal of Biological Chemistry281:9471-9481

 

76. Dally, S., Bredoux, R., Corvazier, E., Andersen, J.P., Clausen, J.D., Dode, L., Fanchaouy, M., Gelebart, P., Monceau, V., Del Monte, F., Gwathmey, J.K., Hajjar, R., Chaabane, C., Bobe, R., Enouf, J.+ 2006

Ca2+-ATPases in non-failing and failing heart: Evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c)

Biochemical Journal 395:249-258

 

75. Dode, L.+, Andersen, J.P.+, Vanoevelen, J., Raeymaekers, L. Missiaen, L. Vilsen, B., Wuytack, F. 2006

Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.

The Journal of Biological Chemistry 281:3182-3189

 

74. Dode, L.+, Andersen, J.P.+, Vanoevelen, J., Raeymaekers, L. Missiaen, L. Vilsen, B., Wuytack, F. 2005

Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses

The Journal of Biological Chemistry 280:39124-39134

 

73. Einholm, A.P., Toustrup-Jensen, M., Andersen, J.P., Vilsen, B.+ 2005

Mutation of Gly-94 in transmembrane segment M1 of Na+,K+-ATPase interferes with Na+ and K+ binding in E2P conformation.

Proceedings of the National Academy of Sciences U.S.A. 101:2776-2781

 

72. Clausen, J.D., Andersen, J.P.+ 2004

Functional consequences of alterations to Thr247, Pro248, Glu340, Asp813, Arg819, and Arg822 at the interfaces between domain P, M3, and L6-7 of sarcoplasmic reticulum Ca2+-ATPase: Roles in Ca2+ interaction and phosphoenzyme processing.

The Journal of Biological Chemistry 279:54426-54437

 

71. Lykke-Møller Sørensen, T., Clausen, J.D., Jensen, A.-M- L., Vilsen, B., Møller, J.V.+, Andersen, J.P.+, Nissen, P.+ 2004

Localization of a K+-binding site involved in dephosphorylation of the sarcoplasmic reticulum Ca2+-ATPase

The Journal of Biological Chemistry, Accelerated Publication, 279:46355-46358

 

70. McIntosh, D.B.+, Clausen J.D., Woolley, D.G., MacLennan, D.H., Vilsen, B., Andersen J.P.+ 2004

Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 279: 32515-32523

 

69. Bobe, R., Bredoux, R., Corvazier, E., Andersen. J.P., Clausen, J.D., Dode, L., Kovács, T., Enouf, J.+ 2004

Identification, expression, function, and localization of a novel (sixth) isoform of the human sarco/endoplasmic reticulum Ca2+ATPase 3 Gene.

The Journal of Biological Chemistry 279: 24297-24306

 

68. Clausen, J.D., Vilsen, B., McIntosh, D.B., Einholm, A.P., Andersen, J.P.+ 2004

Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions.

Proceedings of the National Academy of Sciences U.S.A. 101:2776-2781

 

67. Einholm, A.P., Vilsen, B., Andersen J.P.+ 2004

Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing.

The Journal of Biological Chemistry 279: 15888-15896

 

66. Dode, L.+, Andersen, J.P.+, Leslie, N., Dhitavat, J., Vilsen, B., Hovnanian, A. 2003

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses

The Journal of Biological Chemistry 278: 47877-47889

 

65. Fairclough R.J, Dode L, Vanoevelen J, Andersen J.P., Missiaen L, Raeymaekers L, Wuytack F, Hovnanian A.+ 2003

Effect of Hailey-Hailey disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1).

The Journal of Biological Chemistry 278:24721-24730

 

64. Clausen J.D., McIntosh, D.B., Vilsen, B., Woolley, D.G., Andersen J.P.+ 2003

Importance of conserved N-domain residues Thr441, Glu442, Lys515, Arg560, and Leu562 of sarcoplasmic reticulum Ca2+-ATPase for MgATP binding and subsequent catalytic steps: Plasticity of the nucleotide binding site.

The Journal of Biological Chemistry 278:20245-20258

 

63. Clausen, J.D., Andersen, J.P.+ 2003

Roles of Leu249, Lys252, and Leu253 in membrane segment M3 of sarcoplasmic reticulum Ca2+-ATPase in control of Ca2+ migration and long-range intramolecular communication.

Biochemistry 42:2585-2594

 

62. Dode, L., Vilsen, B., Van Baelen, K., Wuytack, F., Clausen, J.D., Andersen, J.P.+ 2002

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPases (SERCA) 1 and 3 isoforms by steady-state and transient kinetic analyses.

The Journal of Biological Chemistry 277:45579-45591

 

61. Clausen J.D., McIntosh D.B., Woolley D.G., Andersen J.P.+ 2001

Importance of Thr-353 of the conserved phosphorylation loop of the sarcoplasmic reticulum Ca2+-ATPase in MgATP binding and catalytic activity.

The Journal of Biological Chemistry 276:35741-35750

 

60. Andersen, J.P.+, Sørensen, T.L.-M., Povlsen K., Vilsen, B. 2001

Importance of transmembrane segment M3 of the sarcoplasmic reticulum Ca2+-ATPase for control of the

gateway to the Ca2+-sites.

The Journal of Biological Chemistry 276:23312-23321

 

59. Sørensen, T.L.-M., Andersen J.P.+ 2000

Importance of stalk segment S5 for intramolecular communication in the sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 275:28954-28961

 

58. Sørensen, T.L.-M., Dupont, Y., Vilsen, B., Andersen, J.P.+ 2000

Fast kinetic analysis of conformational changes in mutants of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 275:5400-5408

 

57. McIntosh, D.B.+, Woolley, D.G., MacLennan, D.H., Vilsen, B., Andersen, J.P.+ 1999

Interaction of nucleotides with Asp351 and the conserved phosphorylation loop of sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 274:25227-25236

 

56. Vilsen, B.+, Andersen, J.P.+ 1998

Mutation to the glutamate in the fourth membrane segment of Na+,K+-ATPase and Ca2+-ATPase affects cation binding from both sides of the membrane and destabilizes the occluded enzyme forms.

Biochemistry 37:10961-10971

 

55. Andersen, J.P.+, Vilsen, B. 1998

Mutagenesis of sarcoplasmic reticulum Ca2+-ATPase.

Trends in Cardiovascular Medicine 8:41-48.

 

54. Sørensen, T., Vilsen, B., Andersen, J.P.+ 1997

Mutation Lys758Ile of the sarcoplasmic reticulum Ca2+-ATPase enhances dephosphorylation of E2P and inhibits the E2 to E1Ca2 transition.

The Journal of Biological Chemistry 272:30244-30253

 

53. McIntosh, D.B.+, Woolley, D.G., Vilsen, B., Andersen, J.P.+ 1996

Mutagenesis of segment 487FSRDRK492 of sarcoplasmic reticulum Ca2+-ATPase produces pumps defective in ATP binding.

The Journal of Biological Chemistry 271:25778-25789

 

52. Andersen, J.P. + 1995

Functional consequences of alterations to amino acids at the M5S5 boundary of the Ca2+-ATPase of sarcoplasmic reticulum. Mutation Tyr763Gly uncouples ATP hydrolysis from Ca2+ transport.

The Journal of Biological Chemistry 270:908-914

 

51. Andersen, J.P. + 1995

Dissection of the functional domains of the sarcoplasmic reticulum Ca2+-ATPase by site-directed mutagenesis.

Review.

Bioscience Reports 15:243-261

 

50. Andersen, J.P.+, Vilsen, B. 1995

Structure-function relationships of cation translocation by Ca2+- and Na+,K+-ATPases studied by site-directed mutagenesis. Review.

FEBS Letters 359:101-106 + cover of this issue

 

49. Andersen, J.P. + 1994

Mutational analysis of Glu771 of the Ca2+-ATPase of sarcoplasmic reticulum.

Effect of positive charge on dephosphorylation.

FEBS Letters 354:93-96

 

48. Treves, S.+, Larini, F., Menegazzi, P., Steinberg, T.H., Koval, M., Vilsen, B., Andersen, J.P., Zorzato, F. 1994

Alteration of intracellular Ca2+ transients in COS-7 cells transfected with the cDNA encoding skeletal-muscle ryanodine receptor carrying a mutation associated with malignant hyperthermia.

Biochemical Journal 301:661-665

 

47. Nørregaard, A., Vilsen, B. +, Andersen, J.P. + 1994

Transmembrane segment M3 is essential to thapsigargin sensitivity of the sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 269:26598-26601

 

46. Andersen, J.P. +, Vilsen, B. 1994

Amino acids Asn796 and Thr799 of the Ca2+-ATPase of sarcoplasmic reticulum bind Ca2+ at different sites.

The Journal of Biological Chemistry 269:15931-15936

 

45. Clarke, D.M., Loo, T.W., Rice W.R., Andersen, J.P., Vilsen, B., MacLennan, D.H.+ 1993

Functional consequences of alterations to hydrophobic amino acids located in the M4 transmembrane sector of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 268:18359-18364

 

44. Nørregaard, A., Vilsen, B.+, Andersen, J.P.+ 1993

Chimeric Ca2+-ATPase/Na+,K+-ATPase molecules. Their phosphoenzyme intermediates and sensitivity to Ca2+ and thapsigargin.

FEBS Letters 336:248-254

 

43. Andersen, J.P. +, Vilsen, B. 1993

Functional consequences of substitution of the seven-residue segment LysIleArgAspGlnMetAla240 located in the stalk helix S3 of the Ca2+-ATPase of sarcoplasmic reticulum.

Biochemistry 32:10015-10020

 

42. Vilsen, B.+, Andersen, J.P.+ 1992

CrATP-induced Ca2+ occlusion in mutants of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 267:25739-25743

 

41. Andersen, J.P.+, Vilsen, B. 1992

Functional consequences of alterations to Glu309, Glu771, and Asp800 in the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 267:19383-19387

 

40. Vilsen, B.+, Andersen, J.P. + 1992

Mutational analysis of the role of Glu309 in the sarcoplasmic reticulum Ca2+-ATPase of frog skeletal muscle.

FEBS Letters 306:247-250

 

39. Vilsen, B.+, Andersen, J.P. 1992

Deduced amino acid sequence and E1-E2 equilibrium of the sarcoplasmic reticulum Ca2+-ATPase of frog skeletal muscle. Comparison with the Ca2+-ATPase of rabbit fast twitch muscle.

FEBS Letters 306:213-218

 

38. Treves, S.+, Vilsen, B., Chiozzi, P., Andersen, J.P., Zorzato, F. 1992

Molecular cloning, functional expression and tissue distribution of the cDNA encoding frog skeletal muscle calsequestrin.

Biochemical Journal 283:767-772

 

37. Vilsen, B.+, Andersen J.P.+ 1992

Interdependence of Ca2+ occlusion sites in the unphosphorylated sarcoplasmic reticulum Ca2+-ATPase complex with CrATP.

The Journal of Biological Chemistry 267:3539-3550

 

36. Andersen, J.P.+, Vilsen B., MacLennan, D.H. 1992

Functional consequences of alterations to Gly310, Gly770, and Gly801 located in the transmembrane domain of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 267:2767-2774

 

35. Vilsen, B.+, Andersen, J.P.+, MacLennan, D.H. 1991

Functional consequences of alterations to hydrophobic amino acids located at the M4S4 boundary of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 266:18839-18845

 

34. Vilsen, B.+, Andersen, J.P.+, MacLennan, D.H. 1991

Functional consequences of alterations to amino acid residues located in the hinge domain of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 266:16157-16164

 

33. Andersen, J.P.+, Vilsen, B. 1990

Primary ion pumps. Review.

Current Opinion in Cell Biology 2:722-730

 

32. Vilsen, B., Andersen, J.P., Clarke, D.M., MacLennan, D.H.+ 1989

Functional consequences of proline mutations in the cytoplasmic and transmembrane sectors of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 264:21024-21030

 

31. Andersen, J.P., Vilsen, B., Leberer, E., MacLennan, D.H. + 1989

Functional consequences of mutations in the b-strand sector of the Ca2+-ATPase of sarcoplasmic reticulum.

The Journal of Biological Chemistry 264:21018-21023

 

30. Everts, M.E.+, Andersen, J.P., Clausen, T., Hansen, O. 1989

Quantitative determination of Ca2+-dependent Mg2+-ATPase from sarcoplasmic reticulum in muscle biopsies.

Biochemical Journal 260:443-448

 

29. Andersen, J.P. + 1989.

Monomer-oligomer equilibrium of sarcoplasmic reticulum Ca-ATPase and the role of subunit interaction in the Ca2+ pump mechanism. Review.

Biochimica et Biophysica Acta, Reviews on Biomembranes 988:47-72

 

28. Andersen, J. P. +, Vilsen, B. 1988

Radiation inactivation analysis of sarcoplasmic reticulum Ca-ATPase in membrane-bound form and in detergent-solubilized monomeric states.

FEBS Letters 234:120-126

 

27. Jørgensen, P.L.+, Andersen, J.P. 1988

Structural basis for E1-E2 conformational transitions in Na,K-pump and Ca-pump proteins. Review.

The Journal of Membrane Biology 103:95-120

 

26. Vilsen, B., Andersen, J.P.+ 1988

Use of a small TSK GSW high-performance liquid chromatographic column for large-zone chromatographic studies of monomer-oligomer equilibria of membrane protein.

Journal of Chromatography 442:229-236

 

25. Vilsen, B., Andersen, J.P. + 1987

Effect of phospholipid, detergent and protein-protein interaction on stability and phosphoenzyme isomerization of soluble sarcoplasmic reticulum Ca-ATPase.

European Journal of Biochemistry 170:421-429

 

24. Vilsen, B., Andersen, J.P., Petersen, J., Jørgensen, P.L.+ 1987

Occlusion of 22Na+ and 86Rb+ in membrane-bound and soluble protomeric ab-units of Na,K-ATPase.

The Journal of Biological Chemistry 262:10511-10517

 

23. Vilsen, B., Andersen, J.P.+ 1987

Characterization of CrATP-induced calcium occlusion in membrane-bound and soluble monomeric sarcoplasmic reticulum Ca-ATPase.

Biochimica et Biophysica Acta 898:313-322

 

22. Champeil, P., le Maire, M., Andersen, J.P., Guillain, F., Gingold, M., Lund, S., Møller, J.V.+ 1986

Kinetic characterization of the normal and detergent-perturbed reaction cycles of the sarcoplasmic reticulum calcium pump. Rate-limiting step(s) under different conditions.

The Journal of Biological Chemistry 261:16372-16384

 

21. Andersen, J.P.+, Vilsen, B., Collins, J.H., Jørgensen, P.L. 1986

Localization of E1-E2 conformational transitions of sarcoplasmic reticulum Ca-ATPase by tryptic cleavage and hydrophobic labeling.

The Journal of Membrane Biology 93:85-92

 

20. Andersen, J.P.+, Vilsen, B., Nielsen, H., Møller, J.V. 1986

Characterization of detergent-solubilized sarcoplasmic reticulum Ca-ATPase by high-performance liquid chromatography.

Biochemistry 25:6439-6447

 

19. le Maire+, M., Aggerbeck, L.P., Monteilhet, C., Andersen, J.P., Møller, J.V. 1986

The use of high-performance liquid chromatography for the determination of size and molecular weight of proteins: A caution and a list of membrane proteins suitable as standards.

Analytical Biochemistry 154: 525-535

 

18. Jørgensen, P.L.+, Andersen, J.P. 1986

Thermoinactivation and aggregation of ab units in soluble and membrane-bound (Na,K)-ATPase.

Biochemistry 25:2889-2897

 

17. Vilsen, B., Andersen, J.P.+ 1986

Occlusion of Ca2+ in soluble monomeric sarcoplasmic reticulum Ca2+-ATPase.

Biochimica et Biophysica Acta 855:429-431

 

16. Klemens, M.R., Andersen, J.P., Grisham, C.M.+ 1986

Occluded calcium sites in soluble sarcoplasmic reticulum Ca2+-ATPase.

The Journal of Biological Chemistry 261:1495-1498

 

15. Andersen, J.P.+, Jørgensen, P.L. 1985

Conformational states of sarcoplasmic reticulum Ca2+-ATPase as studied by proteolytic cleavage.

The Journal of Membrane Biology 88:187-198

 

14. Andersen, J.P.+, Vilsen, B. 1985

Equilibrium between monomers and oligomers of soluble Ca2+-ATPase during the functional cycle.

FEBS Letters 189:13-17

 

13. Andersen, J.P.+, Jørgensen, P.L., Møller, J.V. 1985

Direct demonstration of structural changes in soluble, monomeric Ca2+-ATPase associated with Ca2+ release during the transport cycle.

Proceedings of the National Academy of Sciences U.S.A. 82:4573-4577

 

12. Andersen, J.P.+, Møller, J.V.+ 1985

The role of Mg2+ and Ca2+ in the simultaneous binding of vanadate and ATP at the phosphorylation site of sarcoplasmic reticulum Ca2+-ATPase.

Biochimica et Biophysica Acta 815:9-15

 

11. Andersen, J.P.+, Lassen, K., Møller, J.V. 1985

Changes in Ca2+ affinity related to conformational transitions in the phosphorylated state of soluble monomeric Ca2+-ATPase from sarcoplasmic reticulum.

The Journal of Biological Chemistry 260:371-380

 

10. Andersen, J.P., le Maire, M., Kragh-Hansen, U., Champeil, P., Møller, J.V.+ 1983

Perturbation of the structure and function of a membraneous Ca2+-ATPase by non-solubilizing concentrations of a non-ionic detergent.

European Journal of Biochemistry 134:205-214

 

9. le Maire, M., Kwee, S., Andersen, J.P., Møller, J.V.+ 1983

Mode of interaction of polyoxyethyleneglycol detergents with membrane proteins.

European Journal of Biochemistry 129:525-532

 

8. Andersen, J.P. +, Skriver, E., Mahrous, T.S., Møller, J.V. 1983

Reconstitution of sarcoplasmic reticulum Ca2+-ATPase with excess lipid. Dispersion of the pump units.

Biochimica et Biophysica Acta 728:1-10

 

7. Andersen, J.P.+, Møller, J.V., Jørgensen, P.L. 1982

The functional unit of sarcoplasmic reticulum Ca2+-ATPase. Active site titration and fluorescence measurements.

The Journal of Biological Chemistry 257:8300-8307

 

6. Møller, J.V.+, Andersen, J.P.+, le Maire, M.+ 1982

The sarcoplasmic reticulum Ca2+-ATPase. Review.

Molecular and Cellular Biochemistry 42:83-107

 

5. Andersen, J.P., Fellmann, P., Møller, J.V., Devaux, P.F. + 1981

Immobilization of a spin-labeled fatty acid chain covalently attached to Ca2+-ATPase from sarcoplasmic reticulum suggests an oligomeric structure.

Biochemistry 20:4928-4936

 

4. Fellmann, P.+, Andersen, J., Devaux, P.F., le Maire, M., Bienvenue, A. 1980

Photoaffinity spin-labeling of the Ca2+-ATPase in sarcoplasmic reticulum: Evidence for oligomeric structure.

Biochemical and Biophysical Research Communications 95:289-295

 

3. Andersen, J.P., le Maire, M., Møller, J.V.+ 1980

Properties of detergent-solubilized and membranous (Ca2+ + Mg2+)-activated ATPase from sarcoplasmic reticulum as studied by sulfhydryl reactivity and ESR spectroscopy. Effect of protein-protein interactions.

Biochimica et Biophysica Acta 603:84-100

 

2. Møller, J.V.+, Lind, K.E., Andersen, J.P. 1980

Enzyme kinetics and substrate stabilization of detergent-solubilized and membraneous (Ca2+ + Mg2+)-activated ATPase from sarcoplasmic reticulum. Effect of protein-protein interactions.

The Journal of Biological Chemistry 255:1912-1920

1. Andersen, J.P., Møller, J.V.+ 1977

Reaction of sarcoplasmic reticulum Ca2+-ATPase in different functional states with 5,5'-Dithiobis (2-nitrobenzoate).

Biochimica et Biophysica Acta 485:188-202

 

 

B. Articles in books and conference proceedings

 

29. Clausen, J.D.+, McIntosh, D.B., Woolley, D.G., Andersen, J.P. 2016

Determination of the ATP affinity of the sarcoplasmic reticulum Ca2+-ATPase by competitive inhibition of [γ-32P]TNP-8N3-ATP photolabeling.

Methods in Molecular Biology Vol. 1377 pp. 233-259, ISBN 978-1-4939-3178-1

 

28. Anthonisen, A.N., Andersen, J.P.+ 2008

Chemistry of calcium pump

Wiley Encyclopedia of Chemical Biology Vol. 1 pp. 212-218, ISBN 978-0-471-75477-0

 

27. Dode, L.+, Raeymaekers, L. Missiaen, L. Vilsen, B., Andersen, J.P., Wuytack, F. 2005

Methods for studying calcium pumps

In: Calcium Signaling (CRC Methods in Signal Transduction Series, 2nd ed. by Putney, J. W.) pp. 335-385 CRC Press, Boca Raton, Fl., U.S.A.

 

26. McIntosh, D.B.+, Clausen, J.D., Woolley, D.G., MacLennan, D.H., Vilsen, B., Andersen, J.P.+ 2003.

ATP binding residues of sarcoplasmic reticulum Ca2+-ATPase.

Annals of the New York Academy of Sciences 986: Proceedings of the 10th International Conference on Na,K-ATPase and Related Cation Pumps. 101-105

 

25. Einholm, A.P., Vilsen, B., Andersen, J.P.+ 2003

Functional consequences of charge reversals of acidic residues in M1 of the SR Ca2+-ATPase.

Annals of the New York Academy of Sciences 986: Proceedings of the 10th International Conference on Na,K-ATPase and Related Cation Pumps. 310-311

 

24. Clausen, J.D., Andersen, J.P.+ 2003

Mutational analysis of Lys252 and its interaction with loop 6-7 in the SR Ca2+-ATPase.

Annals of the New York Academy of Sciences 986: Proceedings of the 10th International Conference on Na,K-ATPase and Related Cation Pumps. 335-337

 

23. Andersen, J.P.+, Clausen, J.D., Einholm, A.P., Vilsen, B. 2003

Mutagenesis of residues involved in control of the Ca2+ entry pathway and conformational changes associated with Ca2+ binding in the SR Ca2+-ATPase.

Annals of the New York Academy of Sciences 986: Proceedings of the 10th International Conference on Na,K-ATPase and Related Cation Pumps. 72-81

 

22. Clausen, J.D., Andersen, J.P.+ 2000

Mutational analysis of the role of Thr353 in phosphorylation of the SR Ca2+-ATPase

In:Na/K ATPase and Related ATPases (Taniguchi, K., and Kaya, S. eds.), Excerpta Medica, Elsevier Science Amsterdam, pp. 409-412

 

21. Sørensen, T.L.-M., Dupont, Y., Vilsen, B., Andersen, J.P.+ 2000

Fast kinetic measurements of mutational effects on conformational changes in SR Ca2+-ATPase.

In:Na/K ATPase and Related ATPases (Taniguchi, K., and Kaya, S. eds.), Excerpta Medica, Elsevier Science Amsterdam, pp. 405-408

 

20. McIntosh, D.B.; Woolley, D.G., MacLennan, D.H., Vilsen, B., Andersen, J.P.+ 2000

Transition state like configuration of the active site in Ca2+-ATPase mutant Asp351®Ala following activation by Ca2+.

In:Na+/K+ ATPase and Related ATPases (Taniguchi, K., and Kaya, S. eds.), Excerpta Medica, Elsevier Science Amsterdam, pp. 401-404

 

19. Andersen, J.P.+, Vilsen, B. 1998

Structure-function relationships of the calcium binding sites of the sarcoplasmic reticulum Ca2+-ATPase.

Acta Physiologica Scandinavica, 163 Suppl.643:45-54

 

18. Vilsen, B.+, Ramlov, D., Andersen, J.P.+ 1997

Functional consequences of mutations in the transmembrane core region for cation translocation and energy transduction in the Na+,K+-ATPase and SR Ca2+-ATPase.

Annals of The New York Academy of Sciences 834:297-309

 

17. Andersen, J.P.+, Sørensen, T., Vilsen, B. 1997

Site-directed mutagenesis analysis of the role of the M5S5 sector of the sarcoplasmic reticulum Ca2+-ATPase.

Annals of The New York Academy of Sciences 834:333-338

 

16. Andersen, J.P.+, Sørensen, T. 1996

Site-directed mutagenesis studies of energy coupling in the sarcoplasmic reticulum Ca2+-ATPase.

Biochimica et Biophysica Acta 1275:118-122

 

15. Andersen, J.P.+, Vilsen, B. 1996

Primary Ion Pumps.

In: Principles of Medical Biology (Bittar & Bittar Eds.) JAI Press Inc.

Cell Chemistry and Physiology: Part III pp. 1-66

 

14. Andersen, J.P.+, Vilsen, B. 1994

Functional domains of sarcoplasmic reticulum Ca2+-ATPase studied by site-directed mutagenesis.

In: The Sodium Pump, Structure, Mechanism, Hormonal Control and its Role in Disease (Bamberg, E., Schoner, W. eds.), Steinkopff, Darmstadt, pp. 98-109

 

13. Vilsen, B.+, Andersen, J.P.+, MacLennan, D.H. 1992

Mutational analysis of the role of Lys684 in the Ca2+-ATPase of sarcoplasmic reticulum.

Acta Physiologica Scandinavica 146:279-284

 

12. Andersen, J.P.+, Vilsen, B. 1992

Structural basis for E1/E1P-E2/E2P conformation changes in the sarcoplasmic reticulum Ca2+-ATPase studied by site-specific mutagenesis.

Acta Physiologica Scandinavica 146:151-159

 

11. Møller, J.V.+, le Maire, M.+, Andersen, J.P.+ 1988

Use of detergents to solubilize the Ca2+-pump protein as monomers and defined oligomers.

Methods in Enzymology 157:261-270

 

10. Vilsen, B.+, Andersen, J.P., Petersen, J., Jørgensen, P.L. 1988

Occlusion of 22Na+ and 86Rb+ in membrane-bound and soluble protomeric ab-units of Na,K-ATPase.

In: The ion pumps: Structure, function and regulation (eds. W.D. Stein) Alan R. Liss, Inc., New York, pp. 33-38

 

9. Vilsen, B., Andersen, J.P.+ 1988

Ca2+ occlusion in monomeric sarcoplasmic reticulum Ca-ATPase.

In: The ion pumps: Structure, function and regulation (ed. W.D. Stein) Alan R. Liss, Inc., New York, pp. 147-154

 

8. Andersen, J.P.+, Vilsen, B.+ 1988

Subunit interaction and conformational states, Ca-ATPase and Na,K-ATPase compared.

In: The Na+,K+-Pump, Part A: Molecular Aspects

Progress in Clinical and Biological Research 268A, 603-622

 

7. Vilsen, B., Andersen, J.P., Petersen, J., Jørgensen, P.L.+ 1988

Occlusion of 22Na+ and 86Rb+ in membrane-bound and soluble protomeric ab-units of Na,K-ATPase.

In: The Na+,K+-Pump, Part A: Molecular Aspects

Progress in Clinical and Biological Research 268A, 383-390

 

6. Andersen, J.P.+, Jørgensen, P.L., Collins, J.H. 1987

Structural basis for E1-E2 transition accompanying active cation transport by Na,K-ATPase and Ca-ATPase. Implications for the pump mechanism.

In: Perspectives of biological energy transduction (M. Mukohata et al eds.) Academic Press, pp. 249-255

 

5. Andersen, J.P.+, le Maire, M., Vilsen, B., Møller, J.V.+ 1987

The selfassociated state of sarcoplasmic reticulum Ca-ATPase and Ca2+ translocation.

In: Perspectives of biological energy transduction (M. Mukohata et al. eds.) Academic Press, pp. 139-146

 

4. Møller, J.V.+, le Maire, M.+, Andersen, J.P.+ 1986

Uses of non-ionic and bile salt detergents in the study of membrane proteins.

In: Progress in protein-lipid interactions (Watts, A. and De Pont J.J.H.H.M., eds) Vol 2, pp. 147-196

 

3. Andersen, J.P.+, Møller, J.V., Jørgensen, P.L. 1983

Conformational transitions in detergent treated and membrane bound Ca2+-ATPase from sarcoplasmic reticulum.

In: Structure and function of membrane proteins (E. Quagliariello and F. Palmieri eds.) Elsevier, Amsterdam, pp. 53-56

 

2. Andersen, J.P.+, Gerdes, U., Møller, J.V. 1983

ATP induced Ca2+ release from monomeric sarcoplasmic reticulum Ca2+-ATPase.

In: Structure and function of membrane proteins (E. Quagliariello and F. Palmieri eds.) Elsevier, Amsterdam, pp. 57-61

1. Møller, J.V.+, Mahrous, T.S., Andersen, J.P., le Maire, M. 1982

Functional significance of quaternary organization of the sarcoplasmic reticulum Ca2+-ATPase.

Z. Naturforsch. 37c:517-521