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Jens Christian Jensenius

Serum mannan-binding lectin-associated serine protease 2 levels in colorectal cancer: relation to recurrence and mortality

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Mannan-binding lectin-associated serine protease 2 (MASP-2) is a plasma protein involved in inflammatory processes. MASP-2 circulates in complex with the protein mannan-binding lectin (MBL) or ficolins, and is activated to recruit the complement system when MBL binds to its targets. The level of MASP-2 is genetically determined, and the aim of the present study was to evaluate the effect of MASP-2 levels on postoperative infection, recurrence and survival.
Original languageEnglish
JournalClinical Cancer Research
Pages (from-to)1441-6
Number of pages6
Publication statusPublished - 2005

    Research areas

  • Adult, Aged, Aged, 80 and over, Cohort Studies, Colorectal Neoplasms, Female, Follow-Up Studies, Humans, Infection, Male, Mannose-Binding Protein-Associated Serine Proteases, Middle Aged, Multivariate Analysis, Neoplasm Recurrence, Local, Neoplasm Staging, Postoperative Complications, Serine Endopeptidases, Survival Analysis, Survival Rate, Time Factors

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