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Jens Christian Jensenius

Preoperative mannan-binding lectin pathway and prognosis in colorectal cancer

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Deficiency of the mannan-binding lectin (MBL) pathway of innate immunity is associated with increased susceptibility to infections. In patients with colorectal cancer (CRC), postoperative infection is associated with poor prognosis. The aim of the present study was to evaluate (1) the relation between the MBL pathway and postoperative infectious complications and survival of patients resected for CRC, and (2) the role of MBL in acute phase response compared to C-reactive protein (CRP).
Original languageEnglish
JournalCancer Immunology, Immunotherapy
Pages (from-to)265-72
Number of pages8
Publication statusPublished - 2005

    Research areas

  • Acute-Phase Reaction, C-Reactive Protein, Colorectal Neoplasms, Female, Humans, Male, Mannose-Binding Lectin, Mannose-Binding Protein-Associated Serine Proteases, Prognosis, Proportional Hazards Models, Serine Endopeptidases, Time Factors, Treatment Outcome

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