Aarhus University Seal / Aarhus Universitets segl

Jens Christian Jensenius

Interaction between a synthetic polypeptide, TIGAL, and Fc receptors on non-bursa-derived chicken lymphoid cells

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Standard

Interaction between a synthetic polypeptide, TIGAL, and Fc receptors on non-bursa-derived chicken lymphoid cells. / Crone, Manni; Jensenius, Jens Christian; Koch, C.

In: Scandinavian Journal of Immunology, Vol. 6, No. 12, 1977, p. 1339-44.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{d322c7fcfb96437d8404726316f996b4,
title = "Interaction between a synthetic polypeptide, TIGAL, and Fc receptors on non-bursa-derived chicken lymphoid cells",
abstract = "Autoradiographic studies have shown that radioiodinated TIGAL binds in vitro to a small but varying fraction of lymphoid cells from bursectomized, agammaglobulinemic chickens, whereas no binding of radioiodinated TGAL or a variety of other radioiodinated antigens can be observed. The binding of [125I]TIGAL is inhibited by antigen-antibody complexes. Radioiodinated antigen-antibody complexes are bound to a similar proportion of the lymphoid cells from bursectomized chickens, and this binding is inhibited by preincubation of the cells with unlabeled TIGAL but not with TGAL. These results indicate a cross-reaction at the level of Fc receptors between determinants on TIGAL and on IgG.",
keywords = "Albumins, Animals, Antigen-Antibody Complex, Autoradiography, Binding Sites, Antibody, Bursa of Fabricius, Chickens, Ferritins, Immunoglobulin Fc Fragments, Iodine Radioisotopes, Leukocytes, Peptides, Rats",
author = "Manni Crone and Jensenius, {Jens Christian} and C Koch",
year = "1977",
language = "English",
volume = "6",
pages = "1339--44",
journal = "Scandinavian Journal of Immunology",
issn = "0300-9475",
publisher = "Wiley-Blackwell Publishing Ltd.",
number = "12",

}

RIS

TY - JOUR

T1 - Interaction between a synthetic polypeptide, TIGAL, and Fc receptors on non-bursa-derived chicken lymphoid cells

AU - Crone, Manni

AU - Jensenius, Jens Christian

AU - Koch, C

PY - 1977

Y1 - 1977

N2 - Autoradiographic studies have shown that radioiodinated TIGAL binds in vitro to a small but varying fraction of lymphoid cells from bursectomized, agammaglobulinemic chickens, whereas no binding of radioiodinated TGAL or a variety of other radioiodinated antigens can be observed. The binding of [125I]TIGAL is inhibited by antigen-antibody complexes. Radioiodinated antigen-antibody complexes are bound to a similar proportion of the lymphoid cells from bursectomized chickens, and this binding is inhibited by preincubation of the cells with unlabeled TIGAL but not with TGAL. These results indicate a cross-reaction at the level of Fc receptors between determinants on TIGAL and on IgG.

AB - Autoradiographic studies have shown that radioiodinated TIGAL binds in vitro to a small but varying fraction of lymphoid cells from bursectomized, agammaglobulinemic chickens, whereas no binding of radioiodinated TGAL or a variety of other radioiodinated antigens can be observed. The binding of [125I]TIGAL is inhibited by antigen-antibody complexes. Radioiodinated antigen-antibody complexes are bound to a similar proportion of the lymphoid cells from bursectomized chickens, and this binding is inhibited by preincubation of the cells with unlabeled TIGAL but not with TGAL. These results indicate a cross-reaction at the level of Fc receptors between determinants on TIGAL and on IgG.

KW - Albumins

KW - Animals

KW - Antigen-Antibody Complex

KW - Autoradiography

KW - Binding Sites, Antibody

KW - Bursa of Fabricius

KW - Chickens

KW - Ferritins

KW - Immunoglobulin Fc Fragments

KW - Iodine Radioisotopes

KW - Leukocytes

KW - Peptides

KW - Rats

M3 - Journal article

C2 - 605365

VL - 6

SP - 1339

EP - 1344

JO - Scandinavian Journal of Immunology

JF - Scandinavian Journal of Immunology

SN - 0300-9475

IS - 12

ER -