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Jens Christian Jensenius

In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin

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In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin. / Friis-Christiansen, P; Thiel, S; Svehag, S E; Dessau, R; Svendsen, P; Andersen, O; Laursen, S B; Jensenius, J C.

In: Scandinavian Journal of Immunology, Vol. 31, No. 4, 01.04.1990, p. 453-60.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Friis-Christiansen, P, Thiel, S, Svehag, SE, Dessau, R, Svendsen, P, Andersen, O, Laursen, SB & Jensenius, JC 1990, 'In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin', Scandinavian Journal of Immunology, vol. 31, no. 4, pp. 453-60.

APA

Friis-Christiansen, P., Thiel, S., Svehag, S. E., Dessau, R., Svendsen, P., Andersen, O., Laursen, S. B., & Jensenius, J. C. (1990). In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin. Scandinavian Journal of Immunology, 31(4), 453-60.

CBE

Friis-Christiansen P, Thiel S, Svehag SE, Dessau R, Svendsen P, Andersen O, Laursen SB, Jensenius JC. 1990. In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin. Scandinavian Journal of Immunology. 31(4):453-60.

MLA

Friis-Christiansen, P et al. "In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin". Scandinavian Journal of Immunology. 1990, 31(4). 453-60.

Vancouver

Friis-Christiansen P, Thiel S, Svehag SE, Dessau R, Svendsen P, Andersen O et al. In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin. Scandinavian Journal of Immunology. 1990 Apr 1;31(4):453-60.

Author

Friis-Christiansen, P ; Thiel, S ; Svehag, S E ; Dessau, R ; Svendsen, P ; Andersen, O ; Laursen, S B ; Jensenius, J C. / In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin. In: Scandinavian Journal of Immunology. 1990 ; Vol. 31, No. 4. pp. 453-60.

Bibtex

@article{904a80cfb20f46c2aa09fe7dfbb25154,
title = "In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin",
abstract = "Conglutinin is a mammalian C-type lectin which agglutinates iC3b-coated erythrocytes. Ingram [13] found that euglobulin from bovine serum may confer partial protection against experimental infections in mice. We now present evidence that the protective activity in euglobulin against infections of BALB/c mice with Salmonella typhimurium is mediated by conglutinin. Conglutinin also demonstrated antibacterial activity against E. coli and S. typhimurium in vitro. The expression of this activity required the presence of heat-labile serum factors and peritoneal exudate or spleen cells, but not antibodies to the bacteria. Antibacterial activity was also demonstrated when the bacteria were pretreated with serum at 37 degrees C before incubation with conglutinin and cells. The activity of conglutinin was not observed when factor I-deficient or EDTA-treated serum was used instead of normal serum. The active peritoneal exudate or spleen cells showed adherence to plastic.",
keywords = "Animals, Bacteria, Blood Physiological Phenomena, Collectins, Escherichia coli, Lectins, Mice, Mice, Inbred BALB C, Phagocytosis, Serum Globulins, Staphylococcal Infections, Thymidine",
author = "P Friis-Christiansen and S Thiel and Svehag, {S E} and R Dessau and P Svendsen and O Andersen and Laursen, {S B} and Jensenius, {J C}",
year = "1990",
month = apr,
day = "1",
language = "English",
volume = "31",
pages = "453--60",
journal = "Scandinavian Journal of Immunology",
issn = "0300-9475",
publisher = "Wiley-Blackwell Publishing Ltd.",
number = "4",

}

RIS

TY - JOUR

T1 - In vivo and in vitro antibacterial activity of conglutinin, a mammalian plasma lectin

AU - Friis-Christiansen, P

AU - Thiel, S

AU - Svehag, S E

AU - Dessau, R

AU - Svendsen, P

AU - Andersen, O

AU - Laursen, S B

AU - Jensenius, J C

PY - 1990/4/1

Y1 - 1990/4/1

N2 - Conglutinin is a mammalian C-type lectin which agglutinates iC3b-coated erythrocytes. Ingram [13] found that euglobulin from bovine serum may confer partial protection against experimental infections in mice. We now present evidence that the protective activity in euglobulin against infections of BALB/c mice with Salmonella typhimurium is mediated by conglutinin. Conglutinin also demonstrated antibacterial activity against E. coli and S. typhimurium in vitro. The expression of this activity required the presence of heat-labile serum factors and peritoneal exudate or spleen cells, but not antibodies to the bacteria. Antibacterial activity was also demonstrated when the bacteria were pretreated with serum at 37 degrees C before incubation with conglutinin and cells. The activity of conglutinin was not observed when factor I-deficient or EDTA-treated serum was used instead of normal serum. The active peritoneal exudate or spleen cells showed adherence to plastic.

AB - Conglutinin is a mammalian C-type lectin which agglutinates iC3b-coated erythrocytes. Ingram [13] found that euglobulin from bovine serum may confer partial protection against experimental infections in mice. We now present evidence that the protective activity in euglobulin against infections of BALB/c mice with Salmonella typhimurium is mediated by conglutinin. Conglutinin also demonstrated antibacterial activity against E. coli and S. typhimurium in vitro. The expression of this activity required the presence of heat-labile serum factors and peritoneal exudate or spleen cells, but not antibodies to the bacteria. Antibacterial activity was also demonstrated when the bacteria were pretreated with serum at 37 degrees C before incubation with conglutinin and cells. The activity of conglutinin was not observed when factor I-deficient or EDTA-treated serum was used instead of normal serum. The active peritoneal exudate or spleen cells showed adherence to plastic.

KW - Animals

KW - Bacteria

KW - Blood Physiological Phenomena

KW - Collectins

KW - Escherichia coli

KW - Lectins

KW - Mice

KW - Mice, Inbred BALB C

KW - Phagocytosis

KW - Serum Globulins

KW - Staphylococcal Infections

KW - Thymidine

M3 - Journal article

C2 - 2185533

VL - 31

SP - 453

EP - 460

JO - Scandinavian Journal of Immunology

JF - Scandinavian Journal of Immunology

SN - 0300-9475

IS - 4

ER -