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Jens Christian Jensenius

Clinical manifestations of mannan-binding lectin deficiency

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Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency may lead to disease. With examples, this review illustrates the diversity of results obtained so far.
Original languageEnglish
JournalMolecular Immunology
Volume43
Issue1-2
Pages (from-to)86-96
Number of pages11
ISSN0161-5890
DOIs
Publication statusPublished - 2006

    Research areas

  • Animals, Autoimmune Diseases, Blood Proteins, Humans, Immunity, Innate, Infection, Mannose-Binding Lectin, Mice, Mice, Knockout, Systemic Inflammatory Response Syndrome, Vascular Diseases

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