This paper reviews the present knowledge of B-L antigens encoded by the chicken B complex as regards to the following aspects: (1) identification and cellular expression, (2) structural studies, (3) evidence for two distinct populations of B-L antigens, (4) mapping of B-L loci of the B complex, (5) B-L and immune response, and (6) the role of the B-L antigens for the control of mixed lymphocyte reactions (MLR) and graft-versus-host (GVH) reactions. It is concluded that B-L antigens of the chicken exhibit extensive homology with mammalian Ia antigens. A genetic map of the B complex is presented.
Original language
English
Journal
Scandinavian Journal of Immunology
Volume
14
Issue
6
Pages (from-to)
591-7
Number of pages
7
ISSN
0300-9475
Publication status
Published - 1981
Research areas
Animals, Chickens, Chromosome Mapping, Fluorescent Antibody Technique, Genes, MHC Class II, Histocompatibility Antigens Class II, Lymphocyte Culture Test, Mixed, Major Histocompatibility Complex