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Association between deficiency of mannose-binding lectin ...
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Jens Christian Jensenius
Association between deficiency of mannose-binding lectin and severe infections after chemotherapy
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
- N A Peterslund, Denmark
- C Koch, Denmark
- Jens Christian Jensenius
- S Thiel
The plasma protein mannose-binding lectin (MBL) activates the complement system by binding to carbohydrate structures presented by microorganisms and thus could be an important component of the innate immune defence system. We measured MBL in patients with leukaemia who were scheduled to undergo chemotherapy (ie, a population especially susceptible to infection) and related the results to severity of infection after chemotherapy. We showed a significant association between low concentrations of MBL and serious infections related to chemotherapy (p
| Original language | English |
|---|---|
| Journal | Lancet |
| Volume | 358 |
| Issue | 9282 |
| Pages (from-to) | 637-8 |
| Number of pages | 2 |
| ISSN | 0140-6736 |
| DOIs | |
| Publication status | Published - 2001 |
- Adult, Bacteremia, Carrier Proteins, Collectins, Denmark, Disease Susceptibility, Female, Humans, Leukemia, Male, Pneumonia, Severity of Illness Index
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ID: 43921830