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Jens Christian Jensenius

Antithrombin 3. Protection against death after injection of thromboplastin

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Intravenous injection of autologous lipoprotein (thromboplastin) or thrombin produced a lethal, hemorrhagic syndrome in chicken embryos. The embryos could be protected from this fatal result by injection of antithrombin III, an alpha(2)-globulin (molecular weight 60,000 to 80,000) purified from human, bovine, and guinea pig blood. Heparin also protected the embryos, but other inhibitors were less protective.
Original languageEnglish
Pages (from-to)517-8
Number of pages2
Publication statusPublished - 1969

    Research areas

  • Alpha-Globulins, Animals, Antithrombins, Blood Protein Electrophoresis, Cattle, Chick Embryo, Electrophoresis, Disc, Guinea Pigs, Hemorrhage, Heparin, Humans, Injections, Intravenous, Molecular Weight, Thromboplastin

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