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Jens Christian Jensenius

Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera

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Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera. / Jensenius, Jens Christian; Mole, L E.

In: European Journal of Immunology, Vol. 8, No. 4, 1978, p. 253-7.

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@article{f9a4f8cdb822463a8d65dfb01487d347,
title = "Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera",
abstract = "Heterologous anti-rabbit IgG antisera have been examined by radioimmunoassay for the occurrence of anti-VH antibody. Most of the sera contained antibody specific for VH allotype determinants (Aal). The antisera contained as much or more anti-al antibody as estimated in conventional alloantisera. It has further been shown that the anti-L chain antibody in all these sera was specific for L chain allotype determinants. Antibody against H chain-dependent L chain conformational determinants or cross-reacting determinants in CHlgamma and CHlalpha could not be demonstrated.",
keywords = "Animals, Antibodies, Anti-Idiotypic, Antibody Specificity, Binding Sites, Antibody, Cross Reactions, Immunoglobulin Allotypes, Immunoglobulin G, Immunoglobulin Heavy Chains, Immunoglobulin Light Chains, Immunoglobulin Variable Region, Isoantigens, Rabbits, Radioimmunoassay",
author = "Jensenius, {Jens Christian} and Mole, {L E}",
year = "1978",
doi = "10.1002/eji.1830080407",
language = "English",
volume = "8",
pages = "253--7",
journal = "European Journal of Immunology",
issn = "0014-2980",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "4",

}

RIS

TY - JOUR

T1 - Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera

AU - Jensenius, Jens Christian

AU - Mole, L E

PY - 1978

Y1 - 1978

N2 - Heterologous anti-rabbit IgG antisera have been examined by radioimmunoassay for the occurrence of anti-VH antibody. Most of the sera contained antibody specific for VH allotype determinants (Aal). The antisera contained as much or more anti-al antibody as estimated in conventional alloantisera. It has further been shown that the anti-L chain antibody in all these sera was specific for L chain allotype determinants. Antibody against H chain-dependent L chain conformational determinants or cross-reacting determinants in CHlgamma and CHlalpha could not be demonstrated.

AB - Heterologous anti-rabbit IgG antisera have been examined by radioimmunoassay for the occurrence of anti-VH antibody. Most of the sera contained antibody specific for VH allotype determinants (Aal). The antisera contained as much or more anti-al antibody as estimated in conventional alloantisera. It has further been shown that the anti-L chain antibody in all these sera was specific for L chain allotype determinants. Antibody against H chain-dependent L chain conformational determinants or cross-reacting determinants in CHlgamma and CHlalpha could not be demonstrated.

KW - Animals

KW - Antibodies, Anti-Idiotypic

KW - Antibody Specificity

KW - Binding Sites, Antibody

KW - Cross Reactions

KW - Immunoglobulin Allotypes

KW - Immunoglobulin G

KW - Immunoglobulin Heavy Chains

KW - Immunoglobulin Light Chains

KW - Immunoglobulin Variable Region

KW - Isoantigens

KW - Rabbits

KW - Radioimmunoassay

U2 - 10.1002/eji.1830080407

DO - 10.1002/eji.1830080407

M3 - Journal article

C2 - 97086

VL - 8

SP - 253

EP - 257

JO - European Journal of Immunology

JF - European Journal of Immunology

SN - 0014-2980

IS - 4

ER -