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Jens Christian Jensenius

Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera

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Heterologous anti-rabbit IgG antisera have been examined by radioimmunoassay for the occurrence of anti-VH antibody. Most of the sera contained antibody specific for VH allotype determinants (Aal). The antisera contained as much or more anti-al antibody as estimated in conventional alloantisera. It has further been shown that the anti-L chain antibody in all these sera was specific for L chain allotype determinants. Antibody against H chain-dependent L chain conformational determinants or cross-reacting determinants in CHlgamma and CHlalpha could not be demonstrated.
Original languageEnglish
JournalEuropean Journal of Immunology
Pages (from-to)253-7
Number of pages5
Publication statusPublished - 1978

    Research areas

  • Animals, Antibodies, Anti-Idiotypic, Antibody Specificity, Binding Sites, Antibody, Cross Reactions, Immunoglobulin Allotypes, Immunoglobulin G, Immunoglobulin Heavy Chains, Immunoglobulin Light Chains, Immunoglobulin Variable Region, Isoantigens, Rabbits, Radioimmunoassay

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