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Jens Christian Jensenius

A haemolytic spot test for the estimation of alloantibody against antigens of the major histocompatibility complex

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A haemolytic technique for the assay of alloantibody has been developed. Titration of alloantiserum was accomplished by placing microdroplets of serum dilutions on agarose layers containing the appropriate erythrocytes. Complement-mediated lysis was procured after the addition of rabbit serum. The assay appeared specific for products of the major histocompatibility gene complex in the rat and in the mouse.
Original languageEnglish
JournalTransplantation
Volume22
Issue5
Pages (from-to)415-9
Number of pages5
ISSN0041-1337
Publication statusPublished - 1976

    Research areas

  • Animals, Antibody Specificity, Antigen-Antibody Reactions, Complement System Proteins, Erythrocytes, Hemolysis, Histocompatibility Antigens, Immune Sera, Immunity, Cellular, Immunologic Techniques, Isoantibodies, Mice, Mice, Inbred DBA, Rabbits, Rats, Rats, Inbred BN, Rats, Inbred Lew, Skin Transplantation, Transplantation, Homologous

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