Jean Farup

2024

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

Liu, S., Ezran, C., Wang, M. F. Z., Li, Z., Awayan, K., Long, J. Z., De Vlaminck, I., Wang, S., Epelbaum, J., Kuo, C. S., Terrien, J., Krasnow, M. A., Ferrell, J. E. & Tabula Microcebus Consortium , Mar 2024, In: Nature Communications. 15, 1, p. 2188 1 p., 2188.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

1 Citation (Scopus)

Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

Espino-Gonzalez, E., Dalbram, E., Mounier, R., Gondin, J., Farup, J., Jessen, N. & Treebak, J. T., Jun 2024, In: Cell Metabolism. 36, 6, p. 1204-1236 33 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

Open Access

4 Citations (Scopus)

2023

Fluorescence-activated cell sorting and phenotypic characterization of human fibro-adipogenic progenitors

Billeskov, T. B., Jensen, J. B., Jessen, N. & Farup, J., 17 Mar 2023, In: STAR Protocols. 4, 1, 26 p., 102008.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

1 Citation (Scopus)

Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals

Wang, J., Mogensen, A.-M. G., Thybo, F., Brandbyge, M., Jensen, J. B., van Hall, G., Agergaard, J., de Paoli, F. V., Miller, B. F., Bøtker, H. E., Farup, J. & Vissing, K., Apr 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 134, 4, p. 1047-1062 16 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

9 Citations (Scopus)

MME+ fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle

Fitzgerald, G., Turiel, G., Gorski, T., Soro-Arnaiz, I., Zhang, J., Casartelli, N. C., Masschelein, E., Maffiuletti, N. A., Sutter, R., Leunig, M., Farup, J. & De Bock, K., Dec 2023, In: Communications Biology. 6, 1, 21 p., 111.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

24 Citations (Scopus)

Regulation of adult stem cell function by ketone bodies

Andersen, O. E., Poulsen, J. V., Farup, J. & de Morree, A., Aug 2023, In: Frontiers in Cell and Developmental Biology. 11, 9 p., 1246998.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

Open Access

1 Citation (Scopus)

Six weeks of high-load resistance and low-load blood flow restricted training increase Na/K-ATPase sub-units α2 and β1 equally, but does not alter ClC-1 abundance in untrained human skeletal muscle

Wang, J., Rindom, E., Groennebaek, T., Sieljacks, P., Jakobsgaard, J. E., Farup, J., Vissing, K., Pedersen, T. H. & de Paoli, F. V., Apr 2023, In: Journal of Muscle Research and Cell Motility. 44, 1, p. 25-36 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

2 Citations (Scopus)

2022

Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets

Zhao, J., Wang, G., Ming, J., Lin, Z., Wang, Y., The Tabula Microcebus Consortium, Wu, A. R. & Yang, C., May 2022, In: Nature Computational Science. 2, 5, p. 317-330 14 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

13 Citations (Scopus)

A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals

Jensen, J. B., Dollerup, O. L., Møller, A. B., Billeskov, T. B., Dalbram, E., Chubanava, S., Damgaard, M. V., Dellinger, R. W., Trošt, K., Moritz, T., Ringgaard, S., Møller, N., Treebak, J. T., Farup, J. & Jessen, N., Oct 2022, In: JCI Insight. 7, 19, 15 p., e158314.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

18 Citations (Scopus)

FIRM: Flexible integration of single-cell RNA-sequencing data for large-scale multi-tissue cell atlas datasets

Ming, J., Lin, Z., Zhao, J., Wan, X., Yang, C., Wu, A. R. & Tabula Microcebus Consortium , Sept 2022, In: Briefings in bioinformatics. 23, 5, 14 p., bbac167.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

File

9 Citations (Scopus)

36 Downloads (Pure)

Sex Hormones and Satellite Cell Regulation in Women

Oxfeldt, M. S., Dalgaard, L. B., Farup, J. & Hansen, M., Apr 2022, In: Translational Sports Medicine. 2022, 12 p., 9065923.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

Open Access

File

62 Downloads (Pure)

2021

Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs

Xiang, X., Zhao, X., Pan, X., Dong, Z., Yu, J., Li, S., Liang, X., Han, P., Qu, K., Jensen, J. B., Farup, J., Wang, F., Petersen, T. S., Bolund, L., Teng, H., Lin, L. & Luo, Y., Jun 2021, In: Molecular Therapy - Nucleic Acids. 24, p. 403-415 13 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

20 Citations (Scopus)

Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs

Xiang, X., Zhao, X., Pan, X., Dong, Z., Yu, J., Li, S., Liang, X., Han, P., Qu, K., Jensen, J. B., Farup, J., Wang, F., Petersen, T. S., Bolund, L., Teng, H., Lin, L. & Luo, Y., 4 Jun 2021, In: Molecular Therapy - Nucleic Acids. 24, p. 403-415 13 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H. & Rossi, F. M. V. & 2 others, Puri, P. L. & Jessen, N., Nov 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e10 25 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

58 Citations (Scopus)

Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors and macrophages from human skeletal muscle biopsies

Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, R. G., Pers, T. H., Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., Aug 2021, In: American journal of physiology. Cell physiology. 321, 2, p. C257-C268 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

9 Citations (Scopus)

Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S. & Jessen, N. & 1 others, Treebak, J. T., Nov 2021, In: Molecular Metabolism. 53, 19 p., 101271.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

32 Citations (Scopus)

2020

Blood flow-restricted resistance exercise alters the surface profile, miRNA cargo and functional impact of circulating extracellular vesicles

Just, J., Yan, Y., Farup, J., Sieljacks, P., Sloth, M., Venø, M., Gu, T., de Paoli, F. V., Nyengaard, J. R., Bæk, R., Jørgensen, M. M., Kjems, J., Vissing, K. & Drasbek, K. R., 2020, In: Scientific Reports. 10, 1, 13 p., 5835.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

44 Citations (Scopus)

Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signalling

Solagna, F., Nogara, L., Dyar, K. A., Greulich, F., Mir, A. A., Türk, C., Bock, T., Geremia, A., Baraldo, M., Sartori, R., Farup, J., Uhlenhaut, H., Vissing, K., Kruger, M. & Blaauw, B., 2020, In: Acta Physiologica. 230, 1, 13 p., e13496.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

File

27 Citations (Scopus)

58 Downloads (Pure)

Mitochondrial Structure and Function in the Metabolic Myopathy Accompanying Patients with Critical Limb Ischemia

Groennebaek, T., Billeskov, T. B., Schytz, C. T., Jespersen, N. R., Bøtker, H. E., Olsen, R. K. J., Eldrup, N., Nielsen, J., Farup, J., De Paoli, F. V. & Vissing, K., Mar 2020, In: Cells. 9, 3, 20 p., 570.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

13 Citations (Scopus)

Role of Metabolic Stress and Exercise in Regulating Fibro/Adipogenic Progenitors

Collao, N., Farup, J. & De Lisio, M., 2020, In: Frontiers in Cell and Developmental Biology. 8, 10 p., 9.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

Open Access

19 Citations (Scopus)

2019

Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function

de Morree, A., Klein, J. D. D., Gan, Q., Farup, J., Urtasun, A., Kanugovi, A., Bilen, B., Van Velthoven, C. T. J., Quarta, M. & Rando, T. A., Nov 2019, In: Science. 366, 6466, p. 734-738 5 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

52 Citations (Scopus)

CIRCULATING EXTRACELLULAR VESICLES RELEASED AFTER ISCHEMIC EXERCISE EXHIBIT AN ALTERED MIRNA PROFILE AND INDUCE PROLIFERATION OF SKELETAL MUSCLE PRECURSOR CELLS

Vissing, K., Just, J., Yan, Y., Farup, J., Larsen, M. S., Venø, M. T., Sieljacks, P., Paoli, F. D., Kjems, J. & Drasbek, K. R., 6 May 2019.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Molecular and cellular adaptations to exercise training in skeletal muscle from cancer patients treated with chemotherapy

Møller, A. B., Lønbro, S., Farup, J., Voss, T. S., Rittig, N., Wang, J., Højris, I., Mikkelsen, U. R. & Jessen, N., Jun 2019, In: Journal of Cancer Research and Clinical Oncology. 145, 6, p. 1449-1460 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

30 Citations (Scopus)

2018

Skeletal muscle stem cell characteristics and myonuclei content in patients with rheumatoid arthritis: a cross-sectional study

Boutrup, R. J., Farup, J., Vissing, K., Kjaer, M. & Mikkelsen, U. R., 1 Jun 2018, In: Rheumatology International. 38, 6, p. 1031-1041 11 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

12 Citations (Scopus)

2017

Differentiation of human fibro-adipogenic progenitors is associated with differential regulation of the non-coding RNAs in a COL1A1 dependent manner

Farup, J., de Paoli, F. V., Giordani, L., Madaro, L., Puri, P. L. & Jessen, N., Jun 2017.

Research output: Contribution to conference › Poster › Research

Lean body mass, muscle fibre size and muscle function in cancer patients during chemotherapy and 10 weeks exercise

Lønbro, S., Farup, J., Bentsen, S., Voss, T. S., Rittig, N., Wang, J., Ørskov, M., Højris, I. & Mikkelsen, U. R., 22 Mar 2017, In: Journal of Cachexia, Sarcopenia and Muscle. 2, 1, p. 1-15 15 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

99 Citations (Scopus)

The role of satellite cells in activity-induced adaptations: breathing new life into the debate

De Lisio, M. & Farup, J., 2017, In: The Journal of Physiology. 595, 19, p. 6225-6226 2 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

1 Citation (Scopus)

2016

Associated decrements in rate of force development and neural drive after maximal eccentric exercise

Farup, J., Rahbek, S. K., Bjerre, J., de Paoli, F. & Vissing, K., 1 May 2016, In: Scandinavian Journal of Medicine and Science in Sports. 26, 5, p. 498-506 9 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

18 Citations (Scopus)

Contraction mode and whey protein intake affect the synthesis rate of intramuscular connective tissue

Holm, L., Klejs Rahbek, S., Farup, J., Vendelbo, M. H. & Vissing, K., 7 Sept 2016, In: Muscle & Nerve. 55, 1, p. 128-130 3 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

22 Citations (Scopus)

Effect of degree of hydrolysis of whey protein on in vivo plasma amino acid appearance in humans

Farup, J., Rahbek, S. K., Storm, A. C., Klitgaard, S., Jørgensen, H., Bibby, B. M., Serena, A. & Vissing, K., 12 Apr 2016, In: SpringerPlus. 5, 1, 18 p., 382.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

19 Citations (Scopus)

Effect of protein quality on recovery after intense resistance training

Rindom, E., Nielsen, M. H., Kececi, K., Jensen, M. E., Vissing, K. & Farup, J., 20 Sept 2016, In: European Journal of Applied Physiology. 116, 11, p. 2225–2236 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

17 Citations (Scopus)

High Intensity Training May Reverse the Fiber Type Specific Decline in Myogenic Stem Cells in Multiple Sclerosis Patients

Farup, J., Dalgas, U., Keytsman, C., Eijnde, B. O. & Wens, I., 31 May 2016, In: Frontiers in Physiology. 7, MAY, p. 193 11 p., 193.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

16 Citations (Scopus)

Satellite cell response to erythropoietin treatment and endurance training in healthy young men

Hoedt, A., Christensen, B., Nellemann, B., Mikkelsen, U. R., Hansen, M., Schjerling, P. & Farup, J., 1 Feb 2016, In: The Journal of Physiology. 594, 3, p. 727-743 17 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

20 Citations (Scopus)

Skeletal muscle stem cell defects in burn-induced cachexia

Farup, J., Torcinaro, A. & Madaro, L., 15 Dec 2016, In: The Journal of Physiology. 594, 24, p. 7153-7154 2 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

2015

Blood flow restricted and traditional resistance training performed to fatigue produce equal muscle hypertrophy

Farup, J., de Paoli, F. V., Bjerg, K. C., Riis, S., Ringgaard, S. & Vissing, K., 19 Nov 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 6, p. 754-763 10 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Enhanced Glycogen Storage of a Subcellular Hot Spot in Human Skeletal Muscle during Early Recovery from Eccentric Contractions

Nielsen, J., Farup, J., Rahbek, S. K., de Paoli, F. V. & Vissing, K., 21 May 2015, In: PLOS ONE. 10, 5, p. e0127808

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

15 Citations (Scopus)

Fibro-adipogenic progenitors in response to acute and prolonged resistance exercise.

Farup, J., Mikkelsen, U. R., Bjerre, J., Rahbek, S. K., de Paoli, F. V., Vendelbo, M., Schjerling, P. & Vissing, K., 13 Jul 2015.

Research output: Contribution to conference › Poster › Research › peer-review

Interactions between muscle stem cells, mesenchymal-derived cells and immune cells in muscle homeostasis, regeneration and disease

Farup, J., Madaro, L., Puri, P. L. & Mikkelsen, U. R., 23 Jul 2015, In: Cell Death & Disease. 6, p. e1830 13 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

112 Citations (Scopus)

No differential effects of divergent isocaloric supplements on signaling for muscle protein turnover during recovery from muscle-damaging eccentric exercise

Rahbek, S. K., Farup, J., de Paoli, F. V. & Vissing, K., Apr 2015, In: Amino Acids. 47, 4, p. 767-778 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

20 Citations (Scopus)

Pericyte Response to Contraction Mode-Specific Resistance Exercise Training in Human Skeletal Muscle

Farup, J., De Lisio, M., Rahbek, S. K., Bjerre, J., Vendelbo, M. H., Boppart, M. D. & Vissing, K., 15 Nov 2015, In: Journal of Applied Physiology. 119, 10, p. 1053-1063 11 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

24 Citations (Scopus)

The Acute Response of Pericytes to Muscle-Damaging Eccentric Contraction and Protein Supplementation in Human Skeletal Muscle

De Lisio, M., Farup, J., Sukiennik, R. A., Clevenger, N., Nallabelli, J., Nelson, B., Ryan, K., Rahbek, S. K., de Paoli, F., Vissing, K. & Boppart, M. D., 15 Oct 2015, In: Journal of Applied Physiology. 119, 8, p. 900-907 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

19 Citations (Scopus)

2014

Effects of divergent resistance exercise contraction mode and dietary supplementation type on anabolic signalling, muscle protein synthesis and muscle hypertrophy

Rahbek, S. K., Farup, J., Møller, A. B., Vendelbo, M. H., Holm, L., Jessen, N. & Vissing, K., 2014, In: Amino Acids. 46, 10

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

40 Citations (Scopus)

Exercise contraction mode and whey protein modulate human skeletal muscle satellite cell activity and muscle cell growth in fiber type specific manners.

Farup, J., Rahbek, S. K., Riis, S., Vendelbo, M., de Paoli, F. V. & Vissing, K., May 2014.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Exercise contraction mode specific regulation of p-mTORC1 pathway signaling.

Rahbek, S. K., Farup, J., Møller, A. B., Vendelbo, M., Holm, L. & Vissing, K., May 2014.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Human Skeletal Muscle Stem Cells in Adaptations to Exercise; Effects of Resistance Exercise Contraction Mode and Protein Supplementation

Farup, J., 2014

Research output: Book/anthology/dissertation/report › Ph.D. thesis

Influence of divergent exercise contraction mode and whey protein supplementation on atrogin-1, MuRF1 and FOXO1/3A in human skeletal muscle

Stefanetti, R. J., Lamon, S., Rahbek, S. K., Farup, J., Zacharewicz, E., Wallace, M. A., Vendelbo, M. H., Russell, A. P. & Vissing, K., 23 Jan 2014, In: Journal of Applied Physiology. 116, 11

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

27 Citations (Scopus)

Influence of exercise contraction mode and protein supplementation on human skeletal muscle satellite cell content and muscle fiber growth.

Farup, J., Rahbek, S. K., Riis, S., Vendelbo, M., de Paoli, F. V. & Vissing, K., 2014, In: Journal of Applied Physiology. 117, 8, p. 898-909 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

58 Citations (Scopus)

Muscle strength and functional performance is markedly impaired at the recommended time point for sport return after anterior cruciate ligament reconstruction in recreational athletes

Larsen, J. B., Farup, J., Lind, M. & Dalgas, U., 24 Nov 2014, In: Human Movement Science. 39C, p. 73-87 15 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

65 Citations (Scopus)

Similar changes in muscle fiber phenotype with differentiated consequences for rate of force development: Endurance versus resistance training

Farup, J., Sørensen, H. & Kjølhede, T., Apr 2014, In: Human Movement Science. 34, p. 109-19

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

16 Citations (Scopus)

Whey protein hydrolysate augments tendon and muscle hypertrophy independent of resistance exercise contraction mode

Farup, J., Rahbek, S. K., Vendelbo, M. H., Matzon, A. S. L., Hindhede, J., Bejder, A., Ringgaard, S. & Vissing, K., Oct 2014, In: Scandinavian Journal of Medicine & Science in Sports Online. 24, 5, p. 788-898 11 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

91 Citations (Scopus)

Jean Farup

Research output

Search results