Jan Asad

  1. 2022
  2. Published

    GLP-1-Receptor Agonists in Neurodegeneration : Neurovascular Unit in the Spotlight. / Monti, Giulia; Gomes Moreira, Diana; Richner, Mette et al.

    In: Cells, Vol. 11, No. 13, 2023, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  3. Published

    Recombinant adeno-associated virus mediated gene delivery in the extracranial nervous system of adult mice by direct nerve immersion. / Richner, Mette; Gonçalves, Nádia Pereira; Jensen, Poul Henning et al.

    In: STAR Protocols, Vol. 3, No. 1, 101181, 03.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2021
  5. Published

    The Prion-Like Spreading of Alpha-Synuclein in Parkinson's Disease : Update on Models and Hypotheses. / Jan, Asad; Gonçalves, Nádia Pereira; Vaegter, Christian Bjerggaard et al.

    In: International Journal of Molecular Sciences , Vol. 22, No. 15, 8338, 08.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  6. Published

    α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. / Delaidelli, Alberto; Richner, Mette; Jiang, Lixiang et al.

    In: Acta Neuropathologica Communications, Vol. 9, No. 1, 105, 06.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy. / Ferreira, Nelson; Richner, Mette; van der Laan, Amelia et al.

    In: Brain Communications, Vol. 3, No. 2, fcab104, 05.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain. / Ferreira, Nelson; Gonçalves, Nádia Pereira; Jan, Asad et al.

    In: Acta Neuropathologica Communications, Vol. 9, 31, 02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2019
  10. Published

    Gene Transfer in Rodent Nervous Tissue Following Hindlimb Intramuscular Delivery of Recombinant Adeno-Associated Virus Serotypes AAV2/6, AAV2/8, and AAV2/9. / Asad, Jan; Richner, Mette; Vægter, Christian Bjerggaard et al.

    In: Neuroscience Insights, Vol. 14, No. November-December, 11.2019, p. 1-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Translational control in brain pathologies : biological significance and therapeutic opportunities. / Delaidelli, Alberto; Jan, Asad; Herms, Jochen et al.

    In: Acta Neuropathologica, Vol. 137, No. 4, 04.2019, p. 535-555.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  12. 2018
  13. Published

    Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. / Jan, Asad; Jansonius, Brandon; Delaidelli, Alberto et al.

    In: Acta Neuropathologica Communications, Vol. 6, No. 1, 54, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2017
  15. Published

    MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation. / Delaidelli, Alberto; Negri, Gian Luca; Jan, Asad et al.

    In: Cell Death and Differentiation, Vol. 24, No. 9, 09.2017, p. 1564-1576.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response. / Jan, Asad; Jansonius, Brandon; Delaidelli, Alberto et al.

    In: Acta Neuropathologica, Vol. 133, No. 1, 01.2017, p. 101-119.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. 2015
  18. Published

    Direct intracerebral delivery of a miR-33 antisense oligonucleotide into mouse brain increases brain ABCA1 expression. [Corrected]. / Jan, Asad; Karasinska, Joanna M; Kang, Martin H et al.

    In: Neuroscience Letters, Vol. 598, 26.06.2015, p. 66-72.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. 2012
  20. Published

    Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation. / Kroth, Heiko; Ansaloni, Annalisa; Varisco, Yvan et al.

    In: The Journal of biological chemistry, Vol. 287, No. 41, 2012, p. 34786-800.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Establishing the links between Aβ aggregation and cytotoxicity in vitro using biophysical approaches. / Jan, Asad; Lashuel, Hilal A.

    In: Methods in molecular biology (Clifton, N.J.), Vol. 849, 2012, p. 227-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2011
  23. Published

    Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species. / Jan, Asad; Adolfsson, Oskar; Allaman, Igor et al.

    In: The Journal of biological chemistry, Vol. 286, No. 10, 11.03.2011, p. 8585-96.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2010
  25. Published

    Preparation and characterization of toxic Abeta aggregates for structural and functional studies in Alzheimer's disease research. / Jan, Asad; Hartley, Dean M; Lashuel, Hilal A.

    In: Nature Protocols (Print), Vol. 5, No. 6, 06.2010, p. 1186-209.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. 2008
  27. Published

    The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity. / Jan, Asad; Gokce, Ozgun; Luthi-Carter, Ruth et al.

    In: Journal of Biological Chemistry, Vol. 283, No. 42, 2008, p. 28176-89.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review