Iver Kristiansen Nordentoft

  1. 2021
  2. Published

    SPTAN1, APC, and FGFR3 Mutation Status and APOBEC Mutation Signatures are Predictive of Mitomycin C Response in Non-muscle-invasive Bladder Cancer. / Skydt Lindgren, Maria; Lamy, Philippe; Lindskrog, Sia Viborg; Christensen, Emil; Nordentoft, Iver Kristiansen; Birkenkamp-Demtröder, Karin; Ulhøi, Benedicte Parm; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: European Urology, 05.11.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer. / Lindskrog, Sia Viborg; Prip, Frederik; Lamy, Philippe; Taber, Ann; Groeneveld, Clarice S.; Birkenkamp-Demtröder, Karin; Jensen, Jørgen Bjerggaard; Strandgaard, Trine; Nordentoft, Iver; Christensen, Emil; Sokac, Mateo; Birkbak, Nicolai J.; Maretty, Lasse; Hermann, Gregers G.; Petersen, Astrid C.; Weyerer, Veronika; Grimm, Marc Oliver; Horstmann, Marcus; Sjödahl, Gottfrid; Höglund, Mattias; Steiniche, Torben; Mogensen, Karin; de Reyniès, Aurélien; Nawroth, Roman; Jordan, Brian; Lin, Xiaoqi; Dragicevic, Dejan; Ward, Douglas G.; Goel, Anshita; Hurst, Carolyn D.; Raman, Jay D.; Warrick, Joshua I.; Segersten, Ulrika; Sikic, Danijel; van Kessel, Kim E.M.; Maurer, Tobias; Meeks, Joshua J.; DeGraff, David J.; Bryan, Richard T.; Knowles, Margaret A.; Simic, Tatjana; Hartmann, Arndt; Zwarthoff, Ellen C.; Malmström, Per Uno; Malats, Núria; Real, Francisco X.; Dyrskjøt, Lars.

    In: Nature Communications, Vol. 12, No. 1, 2301, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2020
  5. Published

    Pervasive chromosomal instability and karyotype order in tumour evolution. / Watkins, Thomas B.K.; Lim, Emilia L.; Petkovic, Marina; Elizalde, Sergi; Birkbak, Nicolai J.; Wilson, Gareth A.; Moore, David A.; Grönroos, Eva; Rowan, Andrew; Dewhurst, Sally M.; Demeulemeester, Jonas; Dentro, Stefan C.; Horswell, Stuart; Au, Lewis; Haase, Kerstin; Escudero, Mickael; Rosenthal, Rachel; Bakir, Maise Al; Xu, Hang; Litchfield, Kevin; Lu, Wei Ting; Mourikis, Thanos P.; Dietzen, Michelle; Spain, Lavinia; Cresswell, George D.; Biswas, Dhruva; Lamy, Philippe; Nordentoft, Iver; Harbst, Katja; Castro-Giner, Francesc; Yates, Lucy R.; Caramia, Franco; Jaulin, Fanny; Vicier, Cécile; Tomlinson, Ian P.M.; Brastianos, Priscilla K.; Cho, Raymond J.; Bastian, Boris C.; Dyrskjøt, Lars; Jönsson, Göran B.; Savas, Peter; Loi, Sherene; Campbell, Peter J.; Andre, Fabrice; Luscombe, Nicholas M.; Steeghs, Neeltje; Tjan-Heijnen, Vivianne C.G.; Szallasi, Zoltan; Turajlic, Samra; Jamal-Hanjani, Mariam; Van Loo, Peter; Bakhoum, Samuel F.; Schwarz, Roland F.; McGranahan, Nicholas; Swanton, Charles.

    In: Nature, Vol. 587, 11.2020, p. 126-132.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published
  7. Published

    Mutational Analysis of Field Cancerization in Bladder Cancer. / Strandgaard, Trine; Nordentoft, Iver Kristiansen; Lamy, Philippe; Christensen, Emil; Thomsen, Mathilde Borg Houlberg; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: Bladder Cancer, Vol. 6, No. 3, 09.2020, p. 253-264.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Epigenetic and transcriptomic consequences of excess X-chromosome material in 47,XXX syndrome-A comparison with Turner syndrome and 46,XX females. / Nielsen, Morten Muhlig; Trolle, Christian; Vang, Søren; Hornshøj, Henrik; Skakkebaek, Anne; Hedegaard, Jakob; Nordentoft, Iver; Pedersen, Jakob Skou; Gravholt, Claus Højbjerg.

    In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, Vol. 184, No. 2, 06.2020, p. 279-293.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Representative Sequencing : Unbiased Sampling of Solid Tumor Tissue. / Litchfield, Kevin; Stanislaw, Stacey; Spain, Lavinia; Gallegos, Lisa L.; Rowan, Andrew; Schnidrig, Desiree; Rosenbaum, Heidi; Harle, Alexandre; Au, Lewis; Hill, Samantha M.; Tippu, Zayd; Thomas, Jennifer; Thompson, Lisa; Xu, Hang; Horswell, Stuart; Barhoumi, Aoune; Jones, Carol; Leith, Katherine F.; Burgess, Daniel L.; Watkins, Thomas B.K.; Lim, Emilia; Birkbak, Nicolai J.; Lamy, Philippe; Nordentoft, Iver; Dyrskjøt, Lars; Pickering, Lisa; Hazell, Stephen; Jamal-Hanjani, Mariam; PEACE Consortium; Larkin, James; Swanton, Charles; Alexander, Nelson; Turajlic, Samra.

    In: Cell Reports, Vol. 31, No. 5, 107550, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2019
  11. Published

    Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer. / Reinert, Thomas; Henriksen, Tenna Vesterman; Christensen, Emil; Sharma, Shruti; Salari, Raheleh; Sethi, Himanshu; Knudsen, Michael; Nordentoft, Iver; Wu, Hsin-Ta; Tin, Antony S; Heilskov Rasmussen, Mads; Vang, Søren; Shchegrova, Svetlana; Frydendahl Boll Johansen, Amanda; Srinivasan, Ramya; Assaf, Zoe; Balcioglu, Mustafa; Olson, Alexander; Dashner, Scott; Hafez, Dina; Navarro, Samantha; Goel, Shruti; Rabinowitz, Matthew; Billings, Paul; Sigurjonsson, Styrmir; Dyrskjøt, Lars; Swenerton, Ryan; Aleshin, Alexey; Laurberg, Søren; Husted Madsen, Anders; Kannerup, Anne-Sofie; Stribolt, Katrine; Palmelund Krag, Søren; Iversen, Lene H; Gotschalck Sunesen, Kåre; Lin, Cheng-Ho Jimmy; Zimmermann, Bernhard G; Lindbjerg Andersen, Claus.

    In: JAMA Oncology, Vol. 5, No. 8, 01.08.2019, p. 1124-1131.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma. / Christensen, Emil; Birkenkamp-Demtröder, Karin; Sethi, Himanshu; Shchegrova, Svetlana; Salari, Raheleh; Nordentoft, Iver; Wu, Hsin-Ta; Knudsen, Michael; Lamy, Philippe; Lindskrog, Sia Viborg; Taber, Ann; Balcioglu, Mustafa; Vang, Søren; Assaf, Zoe; Sharma, Shruti; Tin, Antony S; Srinivasan, Ramya; Hafez, Dina; Reinert, Thomas; Navarro, Samantha; Olson, Alexander; Ram, Rosalyn; Dashner, Scott; Rabinowitz, Matthew; Billings, Paul; Sigurjonsson, Styrmir; Andersen, Claus Lindbjerg; Swenerton, Ryan; Aleshin, Alexey; Zimmermann, Bernhard; Agerbæk, Mads; Lin, Cheng-Ho Jimmy; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: Journal of Clinical Oncology, Vol. 37, No. 18, 06.2019, p. 1547-1557.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Cellular Requirements for Sensing and Elimination of Incoming HSV-1 DNA and Capsids. / Sun, Chenglong; Luecke, Stefanie; Bodda, Chiranjeevi; Jønsson, Kasper L.; Cai, Yujia; Zhang, Bao Cun; Jensen, Søren B.; Nordentoft, Iver; Jensen, Jacob M.; Jakobsen, Martin R.; Paludan, Sren R.

    In: Journal of Interferon and Cytokine Research, Vol. 39, No. 4, 2019, p. 191-204.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2018
  15. Published

    Optimized targeted sequencing of cell-free plasma DNA from bladder cancer patients. / Christensen, Emil; Nordentoft, Iver; Vang, Søren; Birkenkamp-Demtröder, Karin; Jensen, Jørgen Bjerggaard; Agerbæk, Mads; Pedersen, Jakob Skou; Dyrskjøt, Lars.

    In: Scientific Reports, Vol. 8, No. 1, 1917, 01.12.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Discordant molecular subtype classification in the basal-squamous subtype of bladder tumors and matched lymph-node metastases. / Sjödahl, Gottfrid; Eriksson, Pontus; Lövgren, Kristina; Marzouka, Nour-Al-Dain; Bernardo, Carina; Nordentoft, Iver; Dyrskjøt, Lars; Liedberg, Fredrik; Höglund, Mattias.

    In: Modern Pathology, Vol. 31, No. 12, 12.2018, p. 1869-1881.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Serial plasma ctDNA sequencing for early detection of metastatic relapse and monitoring of therapeutic efficacy in Bladder Cancer. / Birkenkamp-Demtröder, Karin; Christensen, Emil; Sethi, Himanshu; Sharma, Shruti; Wu, Hsin-Ta; Nordentoft, Iver Kristiansen; Taber, Ann; Vang, Søren; Lamy, Philippe; Knudsen, Michael; Salari, Raheleh; Shchegrova, Svetlana; Lin, Cheng-Ho Jimmy; Agerbæk, Mads; Zimmermann, Bernhard; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    2018. Poster session presented at 2nd Annual Research Meeting at the Department of Clinical Medicine, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  18. Published

    #3653 Sequencing of plasma cfDNA from patients with locally advanced bladder cancer for surveillance and therapeutic efficacy monitoring. / Birkenkamp-Demtröder, Karin; Christensen, Emil; Sharma, Shruti; Taber, Ann; Agerbæk, Mads; Sethi, Himanshu; Lamy, Philippe; Nordentoft, Iver Kristiansen; Moshkevich, Solomon ; Zimmermann, Bernhard; Lin, Cheng-Ho Jimmy; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    2018. Poster session presented at AACR ANNUAL MEETING 2018, Chicago, .

    Research output: Contribution to conferencePosterResearchpeer-review

  19. Published

    Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures. / Árnadóttir, Sigrid S; Jeppesen, Maria; Lamy, Philippe; Bramsen, Jesper B; Nordentoft, Iver; Knudsen, Michael; Vang, Søren; Madsen, Mogens R; Thastrup, Ole; Thastrup, Jacob; L Andersen, Claus.

    In: Molecular Oncology, Vol. 12, No. 1, 2018, p. 132–147.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2017
  21. Published

    Liquid Biopsies for monitoring treatment response and metastatic relapse in bladder cancer patients. / Birkenkamp-Demtröder, Karin; Christensen, Emil; Nordentoft, Iver Kristiansen; Knudsen, Michael; Taber, Ann; Høyer, Søren; Lamy, Philippe; Agerbæk, Mads; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    2017. Poster session presented at 1st Annual Research Meeting at the Department of Clinical Medicine, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Monitoring treatment response and metastatic relapse in advanced bladder cancer by liquid biopsy analysis. / Birkenkamp-Demtröder, Karin; Christensen, Emil; Nordentoft, Iver Kristiansen; Knudsen, Michael; Taber, Ann; Høyer, Søren; Lamy, Philippe; Agerbæk, Mads; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: European Urology, 25.09.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer. / Thomsen, Mathilde Borg Houlberg; Nordentoft, Iver; Lamy, Philippe; Vang, Søren; Reinert, Line; Mapendano, Christophe Kamungu; Høyer, Søren; Ørntoft, Torben F; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: Scientific Reports, Vol. 7, No. 1, 15.09.2017, p. 11702.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Clinical implications of monitoring circulating tumor DNA in patients with colorectal cancer. / Schøler, Lone V; Reinert, Thomas; Ørntoft, Mai-Britt W; Kassentoft, Christine Gaasdal; Árnadóttir, Sigrid S; Vang, Søren; Nordentoft, Iver; Knudsen, Michael; Lamy, Philippe; Andreasen, Ditte; Mortensen, Frank V; Knudsen, Anders Riegels; Stribolt, Katrine; Sivesgaard, Kim; Mouritzen, Peter; Nielsen, Hans Jørgen; Laurberg, Søren; Ørntoft, Torben F; Andersen, Claus L.

    In: Clinical Cancer Research, Vol. 23, No. 18, 09.2017, p. 5437-5445.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer. / Christensen, Emil; Birkenkamp-Demtröder, Karin; Nordentoft, Iver; Høyer, Søren; van der Keur, Kirstin; van Kessel, Kim; Zwarthoff, Ellen; Agerbæk, Mads; Ørntoft, Torben Falck; Jensen, Jørgen Bjerggaard; Dyrskjøt, Lars.

    In: European Urology, Vol. 71, No. 6, 06.2017, p. 961-969.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Profiling of long non-coding RNAs identifies LINC00958 and LINC01296 as candidate oncogenes in bladder cancer. / Seitz, Anna Katharina; Christensen, Lise Lotte; Christensen, Emil; Faarkrog, Kasper; Ostenfeld, Marie Stampe; Hedegaard, Jakob; Nordentoft, Iver; Nielsen, Morten Muhlig; Palmfeldt, Johan; Thomson, Michelle; Jensen, Michael Theis Solgaard; Nawroth, Roman; Maurer, Tobias; Orntoft, Torben Falck; Jensen, Jorgen Bjerggaard; Damgaard, Christian Kroun; Dyrskjot, Lars.

    In: Scientific Reports, Vol. 7, 395, 24.03.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. / Møller, Andreas Buch; Kampmann, Ulla; Hedegaard, Jakob; Thorsen, Kasper; Nordentoft, Iver; Vendelbo, Mikkel Holm; Møller, Niels; Jessen, Niels.

    In: Scientific Reports, Vol. 7, 43775, 02.03.2017, p. 1-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Liquid biopsy analysis of FGFR3 and PIK3CA hotspot mutations for disease surveillance in bladder cancer. / Christensen, Emil; Birkenkamp-Demtröder, Karin; Nordentoft, Iver Kristiansen.

    2017.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  29. Published

    RHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy. / Strand, Siri; Switnicki, Michal; Moller, Mia; Haldrup, Christa; Storebjerg, Tine M; Hedegaard, Jakob; Nordentoft, Iver; Hoyer, Soren; Borre, Michael; Pedersen, Jakob S; Wild, Peter J; Park, Jong Y; Orntoft, Torben F; Sorensen, Karina D.

    In: OncoTarget, Vol. 8, No. 4, 2017, p. 5774-5788.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2016
  31. Published

    Spatial and temporal clonal evolution during development of metastatic urothelial carcinoma. / Thomsen, Mathilde B H; Nordentoft, Iver; Lamy, Philippe; Høyer, Søren; Vang, Søren; Hedegaard, Jakob; Borre, Michael; Jensen, Jørgen B; Ørntoft, Torben F; Dyrskjøt, Lars.

    In: Molecular Oncology, Vol. 10, No. 9, 11.2016, p. 1450-1460.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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